
House vacation rentals in Punta Santiago, Humacao, Puerto Rico
Find and book unique houses on Airbnb
Top-rated house rentals in Punta Santiago, Humacao, Puerto Rico
Guests agree: these houses are highly rated for location, cleanliness, and more.
Vacation rentals for every style
Get the amount of space that is right for you.
Popular amenities for Punta Santiago, Humacao, Puerto Rico house rentals
House rentals with a pool

Comfortable, private, pool, city location.

Villa Estrella PR (near Airport & Beach)

Renald's Place

Between sea and mountain El Yunque

Fabulous Ocean Views /Private Infinity Pool /4 BR

La Casita: Private Heated Pool W/ Ocean Views

Casa Blanca - Enchanting rainforest stay with pool

Malecon Beach House, Steps to the Caribbean Ocean
Weekly house rentals

Villa Diana surrounded by peace, nature and mountains

Marcelino's Little House

Relax Home

Waterfront, Walk to Restaurants!

Modern Retreat w/ Great View, Hot Tub, & Pool

Rare to Find Two bedrooms House

Mares Tropical house near el Malecon

Private Saltwater Pool House w/Generator & Solar E
Private house rentals

Lush OceanView Retreat Near Beach & El Yunque

Vieques ocean view eco villa+pool

Vista Serena, Salinas PR

Beachfront Family Casa in Paradise

Pool Table-Domino- Family Fun-Lina's House

Chlöe, Colinas del Yunque *Paraiso Escondido* NEW

Seaside, Tennis, Pickleball, Golf, Pool

Private Pool Villa! Get to the point, Puerto Rico
Quick stats about house rentals in Punta Santiago, Humacao, Puerto Rico
Total rentals
50 properties
Nightly prices starting at
$69 CAD before taxes and fees
Total number of reviews
2.6K reviews
Family-friendly rentals
40 properties are a good fit for families
Pet-friendly rentals
10 properties allow pets
Rentals with a pool
20 properties have a pool
Destinations to explore
- Punta Cana Vacation rentals
- San Juan Vacation rentals
- Santo Domingo De Guzmán Vacation rentals
- Las Terrenas Vacation rentals
- Santo Domingo Este Vacation rentals
- La Romana Vacation rentals
- Juan Dolio Vacation rentals
- Bayahibe Vacation rentals
- Carolina Vacation rentals
- Culebra Vacation rentals
- Samana Vacation rentals
- Saint Thomas Vacation rentals
- Family-friendly rentals Punta Santiago, Humacao, Puerto Rico
- Kid-friendly rentals Punta Santiago, Humacao, Puerto Rico
- Rentals with beach access Punta Santiago, Humacao, Puerto Rico
- Rentals with lake access Punta Santiago, Humacao, Puerto Rico
- Beachfront rentals Punta Santiago, Humacao, Puerto Rico
- Rentals with outdoor seating Punta Santiago, Humacao, Puerto Rico
- Rentals with pools Punta Santiago, Humacao, Puerto Rico
- Rentals with a washer and dryer Punta Santiago, Humacao, Puerto Rico
- Rentals with a patio Punta Santiago, Humacao, Puerto Rico
- Pet-friendly rentals Punta Santiago, Humacao, Puerto Rico
- Waterfront rentals Punta Santiago, Humacao, Puerto Rico
- House rentals Humacao Region
- House rentals Puerto Rico
- Yurt Rentals United States
- Yurt Rentals United Kingdom
- Castle Rentals United States
- Houseboats United States
- Holiday Caravans United Kingdom
- Private Island Rentals United States
- Farm Houses United States
- Farm Cottages United Kingdom
- Cabin Rentals Australia
- Luxury Cabins United Kingdom
- Luxury Cabins United States
- Holiday Chalets United Kingdom
- Cottage Rentals United States
- Holiday Cottages United Kingdom
- Mansion Rentals United States
- Villa Rentals United Kingdom
- Holiday Bungalows United Kingdom
- Bungalow Rentals United States
- Condo Rentals United States
- Holiday Apartments Australia
- Holiday Houses United States
- Holiday Houses United Kingdom
- Private Holiday Rentals United Kingdom
- Big House Rentals United States
- Big Cottages Australia
- Large Villas United Kingdom
- House Rentals with a Pool United States
- Cabin Rentals with a Pool United States
- Villas with a Pool United Kingdom
- Apartments with a Hot Tub United States
- Holiday Cottages with a Hot Tub United Kingdom
- Beach Cabins United States
- Beach Condos United States
- Beachfront Rentals United States
- Beach Houses United Kingdom
- Beach Villas United Kingdom
- Coastal Cottages United Kingdom
- Pet-Friendly Vacation Rentals United States
- Pet-Friendly Beach Rentals United States
- Pet-Friendly Cabin Rentals United States
- Dog-Friendly Cottages United Kingdom
- Luxury Dog-Friendly Cottages United Kingdom
- Flamenco Beach
- Rio Mar Village
- Mosquito Bay Beach
- Praia de Luquillo
- Playa del Dorado
- Liquillo Beach
- Playa de Vega
- Distrito T-Mobile
- Playa Puerto Nuevo
- Playa Sun Bay
- Playa el Convento
- Toro Verde Adventure Park
- Playa Maunabo
- Beach Planes
- Playa de los Cabes
- Coco Beach Golf Club
- Playa Puerto Real
- Carabali Rainforest Park
- Punta Bandera Luquillo PR
- Playa de Cerro Gordo
- The Saint Regis Bahia Golf Course
- Playa Las Palmas
- Punta Guilarte Beach
- La Fortaleza