
House vacation rentals in Punta Santiago, Humacao, Puerto Rico
Find and book unique houses on Airbnb
Top-rated house rentals in Punta Santiago, Humacao, Puerto Rico
Guests agree: these houses are highly rated for location, cleanliness, and more.
Vacation rentals for every style
Get the amount of space that is right for you
Popular amenities for Punta Santiago, Humacao, Puerto Rico house rentals
House rentals with a pool

Villa Estrella PR (near Airport & Beach)

Lake Villa House in Toa Baja

Entre mer et montagne El Yunque

Fabulous Ocean Views /Private Infinity Pool /4 BR

Casa Amor Home Esperanza Salt Pool- close to Beach

Casa Blanca - Enchanting rainforest stay with pool

Hilltop Esperanza with ocean views, saltwater pool

Casa Tesoro-pool home. Walk to beaches/restaurants
Weekly house rentals

Lush OceanView Retreat Near Beach & El Yunque

Vieques ocean view eco villa+pool

Relax Home

Private 2BR/2.5 BA W. Ocean View & Heated Infinity Pool

Casa Manatee

Sexy Blue!!

Casita Mykonos #51 (Descuento para Estudiantes)

Getaway in Naguabo
Private house rentals

Tranquil Countryside Retreat

La Casita de Marcelino

Villa Diana 40 mins del concert piscina privada!

Modern Retreat w/ Great View, Hot Tub, & Pool

Stone House PR romántico y moderno

Private Pool Villa! Get to the point, Puerto Rico

Private Saltwater Pool House w/Generator & Solar E

Respir@ Villa Activities
Quick stats about house rentals in Punta Santiago, Humacao, Puerto Rico
Total rentals
50 properties
Nightly prices starting at
$69 CAD before taxes and fees
Total number of reviews
2.6K reviews
Family-friendly rentals
40 properties are a good fit for families
Pet-friendly rentals
10 properties allow pets
Rentals with a pool
20 properties have a pool
Destinations to explore
- Carolina Vacation rentals
- Culebra Vacation rentals
- Saint Thomas Vacation rentals
- Saint Croix Vacation rentals
- Tortola Vacation rentals
- Luquillo Vacation rentals
- Rincón Vacation rentals
- Aguadilla Vacation rentals
- Santo Domingo Vacation rentals
- Punta Cana Vacation rentals
- San Juan Vacation rentals
- Las Terrenas Vacation rentals
- Rentals with pools Punta Santiago
- Kid-friendly rentals Punta Santiago
- Rentals with outdoor seating Punta Santiago
- Rentals with lake access Punta Santiago
- Waterfront rentals Punta Santiago
- Rentals with a washer and dryer Punta Santiago
- Beachfront rentals Punta Santiago
- Rentals with a patio Punta Santiago
- Pet-friendly rentals Punta Santiago
- Family-friendly rentals Punta Santiago
- Rentals with beach access Punta Santiago
- House rentals Humacao Region
- House rentals Puerto Rico
- Yurt Rentals United States
- Yurt Rentals United Kingdom
- Castle Rentals United States
- Houseboats United States
- Holiday Caravans United Kingdom
- Private Island Rentals United States
- Farm Houses United States
- Farm Cottages United Kingdom
- Cabin Rentals Australia
- Luxury Cabins United Kingdom
- Luxury Cabins United States
- Holiday Chalets United Kingdom
- Cottage Rentals United States
- Holiday Cottages United Kingdom
- Mansion Rentals United States
- Villa Rentals United Kingdom
- Holiday Bungalows United Kingdom
- Bungalow Rentals United States
- Condo Rentals United States
- Holiday Apartments Australia
- Holiday Houses United States
- Holiday Houses United Kingdom
- Private Holiday Rentals United Kingdom
- Big House Rentals United States
- Big Cottages Australia
- Large Villas United Kingdom
- House Rentals with a Pool United States
- Cabin Rentals with a Pool United States
- Villas with a Pool United Kingdom
- Apartments with a Hot Tub United States
- Holiday Cottages with a Hot Tub United Kingdom
- Beach Cabins United States
- Beach Condos United States
- Beachfront Rentals United States
- Beach Houses United Kingdom
- Beach Villas United Kingdom
- Coastal Cottages United Kingdom
- Pet-Friendly Vacation Rentals United States
- Pet-Friendly Beach Rentals United States
- Pet-Friendly Cabin Rentals United States
- Dog-Friendly Cottages United Kingdom
- Luxury Dog-Friendly Cottages United Kingdom
- Flamenco Beach
- Rio Mar Village
- Mosquito Bay Beach
- Distrito T-Mobile
- Praia de Luquillo
- Playa del Dorado
- Playa de Vega
- Liquillo Beach
- Playa Puerto Nuevo
- Playa Sun Bay
- Playa el Convento
- Beach Planes
- Playa de los Cabes
- Toro Verde Adventure Park
- Playa Puerto Real
- Playa Maunabo
- Carabali Rainforest Park
- Coco Beach Golf Club
- Punta Bandera Luquillo PR
- Playa de Cerro Gordo
- The Saint Regis Bahia Golf Course
- Playa Las Palmas
- Punta Guilarte Beach
- Stream Thermal Bath