Family-friendly vacation rentals in Rochester

A cozy living area features a patterned sofa with a red accent pillow, complemented by warm wooden flooring. A brick wall provides texture, and natural light filters through the windows. In the background, a dining area with a wooden table and chairs can be seen, along with a staircase.

4.97 out of 5 average rating, 118 reviews

Cottage in Lowertown–Perfect for Mayo & Downtown

In Lowertown-this quaint cottage with modern updates is your home away from home! Fully furnished and a well stocked kitchen make it a wonderful place for overnight stays or longer term rentals. Beautiful patio provides an urban sanctuary at the end of a long day. Close proximity to Mayo Clinic-downtown restaurants, grocery stores and shopping are within walking distance. Two blocks in either direction puts you on the trail system. Public transit 1 ½ blocks away and a laundromat is ½ block away.

A garden-level apartment is accessed via a gravel driveway that leads to a charming home. Lush greenery surrounds the path, and the structure features a mix of siding colors, with large windows framed by blue shutters, creating an inviting exterior appearance.

4.94 out of 5 average rating, 231 reviews

Woodland Retreat, Full private walkout lower level

Peaceful retreat down gravel driveway 15 min from Mayo Clinic. Enjoy your own apartment with private backyard walkout entrance to the lower level of our home. You will have a bedroom, living area, kitchenette with mini fridge, microwave and toaster oven (no conventional stove/oven), bathroom w/ tub & shower, pingpong table, laundry, and patio with fire ring. You may hear piano music weekday afternoons, since I give lessons (usually 3-6 pm; a bit earlier in summer) NEW HEATED FLOORS w/thermostat

4.98 out of 5 average rating, 335 reviews

A charming two-story structure is shown with a welcoming red exterior and a large wrap-around covered deck. Brightly colored flower pots accent the porch, and two decorative wagon wheels enhance the façade. Well-maintained grass and a concrete path lead to the entrance.

Guest suite in Rochester

Porch on 4th

Welcome to your home, away from home. Private, Clean & Comfortable ! 1200 square feet in a 2nd floor apartment with 2 bedrooms & spacious living area. We are a 5 minute drive to downtown Mayo Clinic, St. Mary's Hospital & many shopping areas. Walking distance to convenience store. We are in an easy access area to get to the many things Rochester has to offer. Inspected & licensed as rental property by the City of Rochester. Smoke free. We allow service animals & 1 small dog under 25 pounds.

A single-story home is shown, featuring a red front door and a well-maintained exterior. Vibrant autumn trees with golden leaves line the walkway, and a grassy area is depicted in front of the house, inviting a sense of tranquility to the setting.

4.87 out of 5 average rating, 417 reviews

Mayo Downtown's Prairie Home Retreat

Nestled in a serene corner, this home offers a perfect blend of tranquility and accessibility; being near the Mayo campus and Rochester's key attractions. Enjoy comfortable beds, a well-appointed kitchen, and a fenced yard with patio gardens. It's an excellent spot for family bonding, featuring three smart TVs, rapid Wi-Fi, and a variety of indoor and outdoor entertainment options. We strive to accommodate flexible check-in/check-out arrangements whenever feasible. Rollator accessible.

A cozy living room space features a beige couch adorned with decorative pillows and a low coffee table. The white brick wall serves as a backdrop for a fireplace, which is framed by a wooden mantle decorated with artwork and a wreath. Natural light enters through a window.

4.97 out of 5 average rating, 272 reviews

Restful sanctuary close to Mayo Clinic

This cozy space has private, self-entrance with off-street parking at no cost...a mere 2.5 miles or 10 minute drive to the Mayo Clinic downtown. Located in a quiet neighborhood in northwest Rochester. Easy access to highways, grocery store, coffee shop, Target, restaurants and biking/walking trail. Completely furnished with linens, hair-dryer, Netflix and Hulu, Smart TV and Wi-fi....and a Keurig Coffee maker with enough coffee pods to get you started. Truly, a home away from home!

Home in Historic Southwest

The open-concept living area showcases vaulted ceilings and skylights, enhancing natural light. Two light grey sofas frame a wooden coffee table on a colorful area rug. A dining area with a large table and chairs is visible, with stairs leading to the upper level in the background.

4.97 out of 5 average rating, 196 reviews

Spacious Modern Home Near Mayo, St. Mary's Campus

- 5 min walk to Mayo Clinic, St. Mary’s campus - 3 bedrooms, 3 bathrooms, and a loft - unique design with vaulted ceiling and skylights in the style of Frank Lloyd Wright, one of its kind in the whole neighborhood - two-car garage + another dedicated parking space outside - walkable and safe family-friendly neighborhood close to downtown and all amenities - outside front and back patios - fusball play table - dedicated workspace - high speed wifi - Apple TVs - washer and dryer

4.97 out of 5 average rating, 147 reviews

The living area is highlighted by a modern gray sofa, accentuated with textured cushions. A sleek coffee table holds a glass vase with greenery, while art pieces adorn the wall. Natural light filters through sheer curtains, creating a bright and inviting space.

Home in Kutzky

Entire Boutique Home Kutzky Park ★ Walk to Mayo ★

Welcome to Asfar house! Expertly designed and centrally-located in a desirable Kutzky Park neighborhood, walking distance to Mayo Clinic, restaurants and shops. Whether you are relocating or visiting Rochester, this house will be sure to impress. Blasting fast WIFI, 3 relaxing bedrooms & a fully equipped kitchen. A perfect retreat to enjoy the coffee bar, read, watch a Netflix episode, play and relax. Enjoy the perfect shower, conveniently adjoined with free washer and dryer.

4.96 out of 5 average rating, 175 reviews

The Sierra! Close to Mayo Clinic

Gorgeous Home close to Mayo Clinic. The family room and living include Roku 4K UHD TVs, Foosball, and darts. Free WIFI. Office on Main with great light. Beautiful front porch or patio in the rear. TVs Enjoy luxurious finishes like crown molding, a fireplace in the family room, quartz countertops and a stunning vaulted Primary Ensuite with custom tile work and paneled doors. All of this is conveniently just minutes from downtown!

A modern kitchen is displayed, featuring white cabinetry contrasted against a deep blue wall. A stainless steel oven and a retro-style microwave are present on the countertop, alongside a coffee maker and kitchen utensils. Natural light enters through the window above the sink.

4.82 out of 5 average rating, 572 reviews

Cozy home next to Mayo Clinic & historic parks!

Cozy single level 2 bedroom, 1 bath. Fully furnished kitchen with TV, WiFi, and smart lock. It’s a 1.6 miles to Mayo Clinic. Walking distance to Historic Quarry Hill Park and Silver Lake Park. City bus line to Mayo Clinic 1/2 block away. Newly remodeled bathroom with full linen and toiletries. Quiet neighborhood, with full driveway parking. We also have a baby gate for the stairs. Enjoy your next home away from home !

4.98 out of 5 average rating, 202 reviews

The exterior features a two-story structure with a wooden facade and large garage doors. A set of stairs leads up to the entrance, surrounded by natural stone landscaping and colorful flowers. Trees and greenery provide a serene atmosphere.

Condo in Rochester

Cedar Loft is a tranquil retreat

If you are looking for a quiet retreat w/private entrance outside the city, you are home. Trees are outside every window with palpable serenity yet is still an easy ten-minute drive to downtown Rochester. This is a family-friendly place with crib and changing table. This is not a party house. It has a kitchenette so we will provide information to restaurants and grocery stores within 5 minutes.

A modern kitchen is equipped with stainless steel appliances, including a refrigerator, microwave, and dishwasher. A circular dining table with four white chairs is set in the center, adorned with a vase of flowers. Dark tiles provide contrast to the bright cabinetry, enhancing the functional space.

4.97 out of 5 average rating, 147 reviews

St. Augustine’s Mint Mayo Clinic WALK GARAGE!

Welcome to St. Augustine’s Mint House Mayo Clinic!! Where comfort and cleanliness meet compassion ❤️. I look forward to hosting you. THE HOUSE IS A DUPLEX! St. Augustine’s Mint House is the main level apt. DO NOT GO UPSTAIRS!! St. Augustine’s Mint Loft is the upstairs apt. Both apartments have separate keyed apartment entries but share the main entry foyer/laundry.

4.92 out of 5 average rating, 102 reviews

A modern multi-story building is displayed, featuring large glass windows and a combination of brick and smooth facade materials. The entrance is framed by a wide overhang, and surrounding trees add greenery to the welcoming exterior.

Apartment in Kutzky

2 bdrm Furnished Apt Across from Saint Marys Hosp

Private wifi network in each unit, garage parking ($20/night), located directly across the street from Saint Mary's Hospital. We have a state of the art fitness center, game simulator, in room complimentary pour over coffee with beans from local cafe/roaster. Walking distance to restaurants and grocery stores.

Popular amenities for Rochester family-friendly rentals

Kitchen

Wifi

Pool

Free parking on premises

Air conditioning

Family-friendly home rentals with a hot tub

A light-filled living room features a soft beige sofa with blue accent pillows. Two teal chairs with decorative pillows are positioned nearby. A small coffee table is centered in the room, with a mirror and lamps providing ambient lighting. Large windows offer views of the outside.

4.86 out of 5 average rating, 7 reviews

Gorgeous Rochester-Mayo Clinic Home

A living area showcases a coffee table with a glass top, positioned in front of a mounted television. Floral-patterned curtains frame a window, while a small vase with flowers and a box are placed on the table, enhancing the inviting atmosphere of the space.

4.7 out of 5 average rating, 10 reviews

Elegant &Secure Family Abode

Modern Cozy house, near Mayo Clinic

A spacious studio apartment is showcased with large windows that allow natural light to fill the room. A comfortable bed sits on one side, complemented by a stylish seating area featuring two chairs. Soft textures are present with a plush rug, enhancing the modern aesthetic.

Guesthouse in Rochester

Private Stay Away From It All

4.99 out of 5 average rating, 77 reviews

A rustic log cabin is framed by a lush green lawn, complemented by a natural stone chimney. A covered porch extends across the front, with large windows allowing ample light into the structure. Nearby greenery and trees add to the serene outdoor setting.

Cabin in Wykoff

Rochester Luxury Log cabin Whispering Oaks Retreat

A well-maintained pathway leads to a welcoming entrance of the home, bordered by lush greenery and colorful flowers. The front porch, featuring comfortable seating, is shaded by a large overhang, while a lamp post adds gentle illumination to the landscaped yard.

5 out of 5 average rating, 23 reviews

Beautiful, Private, Nature & Hot tub! 4m to Mayo

Skyway connected Extended Stay in Rochester

A serene outdoor space is highlighted by a stunning sunset over lush greenery. Comfortable seating is arranged around a fire pit, surrounded by blooming flowers and various plants. A swimming pool is visible in the background, nestled into the landscape.

5 out of 5 average rating, 48 reviews

RARE! Pool, hot tub, garden &chickens! 4m to Mayo

Family- and pet-friendly home rentals

4.92 out of 5 average rating, 38 reviews

A modern kitchen features sleek white cabinetry and a matching countertop. Essential appliances, including a black stove, microwave, and stainless-steel dishwasher, are present. Natural light enters through a window above the sink, which is adorned with stylish fixtures and greenery for a touch of freshness.

Home in Kutzky

Modern 2 Bd Close to Downtown / Mayo, free parking

Camper/RV in Zumbro Falls

An RV is situated among lush greenery, featuring a wooden deck and steps leading to the entrance. A circular arrangement of black Adirondack chairs surrounds a gravel area, creating a cozy gathering space. A BBQ grill is positioned at the side of the RV.

4.91 out of 5 average rating, 46 reviews

The Flipping RV: Lake Zumbro

A modern single-story home is showcased, featuring a mix of dark exterior siding and large windows that allow natural light to flood the interior. A small staircase leads up to the front door, framed by well-maintained greenery and potted plants.

5 out of 5 average rating, 7 reviews

Rest Easy in Rochester

The exterior of a spacious single-family home is shown from a street view, featuring a well-maintained lawn with trees lining the property, a wide driveway leading to a two-car garage, and nearby street signage indicating the neighborhood's name.

4.77 out of 5 average rating, 39 reviews

Rose house-4 BR-2 Bath-4 miles from Mayo Clinic

4.97 out of 5 average rating, 135 reviews

Bungalow in Rochester

Betty’s Bungalow: A Dharma Dwellings Home

The exterior of a historic home is displayed, featuring a welcoming porch with a green front door. A spacious lawn surrounds the house, complemented by trees and neighboring structures visible in the background. The roof has distinctive angles, adding to the property’s character.

4.98 out of 5 average rating, 61 reviews

Large 4 Bedroom Downtown Home JUST BLOCKS TO MAYO

4.95 out of 5 average rating, 181 reviews

A log home with a red roof and green accents is surrounded by trees and grass. A front porch with a welcoming entrance features a decorative wreath, and a spacious driveway leads to a garage. Sunlight bathes the exterior in bright colors.

Home in Stewartville

"Walden Pond" Adventure Amidst 44 Private Acres

A charming single-family home with a light green exterior is featured. A concrete pathway leads to the front door, bordered by a well-maintained grassy area. A mailbox stands at the entry, and green waste bins are positioned nearby. The roof has a gable design, enhancing the home's character.

4.93 out of 5 average rating, 42 reviews

“2BR 2BA– Walk to downtown, Silver Lake

Family-friendly home rentals with a pool

4.89 out of 5 average rating, 18 reviews

A modern living area features a grey sofa and a black accent chair, accompanied by two circular ottomans. A flat-screen television is positioned on a wooden console. Large windows allow natural light to fill the space, highlighting the neutral color palette and geometric area rug.

Apartment in Kutzky

One Bedroom Apartment

An open living area showcases a gray sofa and a green chair, complemented by a round wood coffee table. Two framed artworks are displayed on the light-colored wall, while modern kitchen appliances are visible in the background, illuminated by soft natural light.

4.15 out of 5 average rating, 13 reviews

Two Bedroom Luxury in Rochester

4.83 out of 5 average rating, 35 reviews

A modern bathroom is equipped with a spacious vanity featuring a large mirror and ample storage. A bathtub with a shower unit is present, along with a white toilet. Soft towels are neatly arranged on a rack, highlighting a clean and functional space.

Apartment in Kutzky

Studio Apartment

A modern two-story single-family home is depicted, featuring a clean white and black exterior. A large garage door complements the ample driveway. The well-maintained lawn offers a green backdrop, while the sunlit blue sky enhances the overall inviting appearance of the property.

5 out of 5 average rating, 9 reviews

4bd/2.5bth Single-Family Home Close to Mayo

A modern single-family home is depicted, featuring a sleek black exterior with a prominent garage. The driveway leads to a well-maintained lawn, flanked by young trees and ornamental grasses, creating an inviting entrance. Clear blue skies complete the serene setting.

5 out of 5 average rating, 5 reviews

Unit 2377J | 3bd/2bth | Single-Family Home

An open kitchen area features modern appliances, including a stove and refrigerator. A large island with seating provides a central gathering space. Natural light floods the living area through sliding glass doors, which lead to an outdoor patio with green views.

4.88 out of 5 average rating, 8 reviews

Luxury 1 bedroom Serenity