Vacation rentals in Muscatine

Find and book unique accommodations on Airbnb

Top-rated vacation rentals in Muscatine

Guests agree: these stays are highly rated for location, cleanliness, and more.

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Guest favourite
Home in Davenport
4.94 out of 5 average rating, 134 reviews

Small Town Vibes 3bdrm/2 bath house

Kick back and relax in your home away from home. My home offers large quartz island, coffee station, and dining. There's a traditional front porch and covered deck/porch out back as well great for work groups. Alley parking and front street parking with room for a trailer or larger trucks. Small town feel close to the Mississippi, but less than 10 minutes to downtown. Perfect for MVP fair week, Bix, Farmers Market, River Bandits, Credit Island visit, and much more. There are 3 bdrms & 2 baths!

Guest favourite
A historic four-bedroom home is captured with tall trees framing the exterior, set against a clear blue sky. The architectural features include a prominent turret and multiple windows, reflecting the home's charm. A snow-dusted yard leads to a view of the nearby Mississippi River.
Home in Muscatine
4.96 out of 5 average rating, 150 reviews

Historic West Hill Retreat

Beautiful historic 4 bedroom, 4 bath home within walking distance to shopping, bars/restaurants and all that downtown Muscatine has to offer. Enjoy sweeping views of the Mississippi River from several vantage points in and outside this home. The 3000 sf interior offers many places to gather and relax. Two of the bedrooms have on suite full baths. The other two bedrooms share a full bath. Additional amenities include, fully equipped kitchen, laundry, games, grill, outdoor entertainment area.

Guest favourite
A tranquil view of the Rock River is presented, featuring a wooden dock extending into the water. Lush trees line the shore, and the sky displays soft blue hues with wispy clouds. The calm water reflects the natural surroundings, creating a serene atmosphere.
Cabin in Moline
4.94 out of 5 average rating, 233 reviews

Riverfront Firepit, Kayaks, Huge Deck

Firepit ready for relaxing nights by the river. Kayaks included for warm days Wake up to sweeping Rock River views, sip coffee on the wrap-around deck, paddle out in the kayaks, and end your evening by the firepit as the sky glows at sunset. This eclectic riverfront bungalow blends vibrant décor with cozy comfort and seamless indoor-outdoor living. Perfect for girls’ weekends, fishing trips, romantic escapes, or peaceful fall getaways — just steps from the water and minutes to shops and dining

Top guest favourite
Loft in Muscatine
5 out of 5 average rating, 16 reviews

Downtown;Walk to Shops, Restaurants, Entertainment

Located in the heart of Downtown - Enjoy great views of historic downtown Muscatine. - Steps away from restaurants, pubs, museums, and shopping. - Two blocks away from Mississippi Riverfront. - Enjoy a walk or bike ride along the trail system. - 2 bedrooms - one King and one Queen bed - WiFi, Smart TV and charging stations - Secure, safe location There are stairs to climb to reach the loft, and there is no elevator, but the spectacular views of Downtown are worth it when you get there!

Guest favourite
A spacious home is visible with a combination of brick and siding exterior, featuring multiple gables and a large covered porch. A manicured lawn extends toward a serene pond, enhancing the natural surroundings. Clear blue skies contribute to the relaxing outdoor atmosphere.
Home in Morning Sun
4.91 out of 5 average rating, 255 reviews

Buckman's Bed and Breakfast (5 Bedrooms+)

Enjoy the comfort and welcoming atmosphere of a home built to entertain family & friends. There are 5 guest bedrooms rooms: Room 1-King bed, sofa bed & recliner Room 2-Queen & sofa bed Room 3-Twin beds & convertible sofa Room 4-Queen & sofa bed Room 5-King & recliner Rooms 1,2 &5 have in suite bathrooms. Bathroom for room 4 is next door. Rooms 2 &3 share an inner door; ideal for parents with children. Breakfast is included. To book a room instead of the house, see separate listings.

Top guest favourite
Home in Muscatine
5 out of 5 average rating, 17 reviews

Pearl of Mulberry

Welcome to the Pearl of Mulberry! This cozy and elite property is perfect for business travel, families or small groups. Centrally located in Muscatine, you can quickly and easily get to our beautiful downtown area as well as the soccer fields and sports dome. Enjoy the convenience of amenities during your stay with a fully equipped kitchen, outdoor grill and full size washer and dryer. The Pearl of Mulberry will help you feel at home while you're traveling in picturesque Muscatine.

Top guest favourite
Guest suite in Rock Island
4.97 out of 5 average rating, 343 reviews

Large apartment in the lower-level of our house

The lower-living space is 1000+ sq ft in the lower level of our ranch house. It is very quiet and private. The front door is shared and is just 2 steps to the AirbNb entrance. We are 5 min off I-280 / I-74 near Augustana College, John Deere, Rock Island Arsenal, etc. Cozy apartment with kitchen w/dining, large private bathroom, family room w/dining area, couch/hide-a-bed and futon, large bedroom and a 2nd bedroom/workout room. Free parking in our driveway and high speed internet.

Top guest favourite
A vibrant garden of zinnias in shades of pink and orange flourishes in the foreground, leading to a red barn in the background. The barn features a gabled roof and is surrounded by greenery, creating a serene outdoor scene.
Barn in Solon
4.97 out of 5 average rating, 144 reviews

Beautiful, cozy barn in the quiet countryside

Come enjoy a relaxing get away on beautiful Sugar Bottom Road. A great place for the outdoor enthusiast, no matter the season. Ideal also for quiet relaxation and privacy. We are a small acreage just 15 minutes from Iowa City, 7 minutes from Solon, and 30 minutes from the Cedar Rapids airport. Our converted barn is at the back of the property, behind the house. There is a separate road leading back to the barn for super convenient parking. It’s rustic, cozy, warm and inviting.

Guest favourite
An outdoor terrace is visible, featuring a railing with various potted plants and decorative seating. The space offers views of the nearby river and surrounding area, enhancing the ability to enjoy the outdoors. The brick exterior of the building adds a historic element.
Loft in Muscatine
4.94 out of 5 average rating, 244 reviews

The Emerald Loft Apartment

Stay in a Historic District Downtown loft! River views. Nearby park, playground, bike trails, boat ramps & marina. Shopping, live music, & restaurants. Private entry with 1,000 sqr ft of space, open concept, full kitchen, TV, laundry, private bath, literally right in middle of everything. Check in at Creations by Oz "Jewelry, Wine, & Unique Finds". Enjoy a glass of wine upon check-in. Come hungry. Photo comments provide dining options within steps of the Emerald Room.

Top guest favourite
A bright and open kitchen features white cabinetry and a large island with dark granite countertops. A round dining table is set with two place settings, and sliding glass doors provide access to a private outdoor deck area. Natural light fills the space.
Home in Bettendorf
4.93 out of 5 average rating, 188 reviews

Amazing updated 2 bedroom home 2 bath.

Your family will be close to everything when you stay at this centrally-located place. In the heart of Bettendorf. Close to interstates, shopping, Bettendorf Sports Complex, Village of East Davenport. Off street parking. Garage access if needed. Plenty of space two beds and bath on main level. Lower rec room has additional bath and sleeping accommodations. Quiet street. Fenced in back yard. Private deck. This house has everything for a short stay or long stay.

Guest favourite
A wooden deck extends over the serene water, showcasing a calm river reflecting the greenery on the opposite bank. Potted plants sit on the edge of the deck, surrounded by an inviting natural landscape.
Cottage in Rock Island
4.87 out of 5 average rating, 236 reviews

Rock River Escape

Enjoy your coffee, a nice bbq dinner, glass of wine, a good book, or just enjoy the sweeping views out of this cute bungalow. With 180 ft of unobstructed river views and river access, bring your fishing poles and get ready to relax and enjoy watching the water slowly drift by at this centrally located bungalow in a quiet residential neighborhood. Firepit with firewood provided. No parties allowed so please do not inquire about them.

Top guest favourite
A cozy living area features a gray sectional sofa with decorative pillows. A flat-screen smart TV sits on a shelf illuminated in purple tones, displaying various streaming options. Natural light enters through the window, while a door leads outside, enhancing the welcoming atmosphere.
Home in Moline
4.92 out of 5 average rating, 202 reviews

The Little Gem

Kick back and relax in this calm, stylish space. We have 1 bedroom with a queen bed, smart TVs and USB charging lamps. Feel free to prepare a meal in our stocked kitchen or prepare yourself a cup of coffee. This location is right off the Avenue of the Cities and is near grocery stores, restaurants and gas stations.

Popular amenities for Muscatine vacation rentals

When is the best time to visit Muscatine?

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Quick stats about vacation rentals in Muscatine

  • Total vacation rentals

    Explore 20 vacation rentals in Muscatine

  • Nightly prices starting at

    Muscatine vacation rentals start at $110 CAD per night before taxes and fees

  • Verified guest reviews

    Over 800 verified reviews to help you choose

  • Family-friendly vacation rentals

    10 properties offer extra space and kid-friendly amenities

  • Wifi availability

    10 of Muscatine vacation rentals include wifi access

  • Popular amenities for guests

    Guests love Kitchen, Wifi, and Pool across Muscatine rentals

  • 4.8 Average rating

    Muscatine stays are highly rated by guests—averaging 4.8 out of 5!

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