
Guesthouse vacation rentals in San Luis Obispo
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Top-rated guesthouses in San Luis Obispo
Guests agree: these guesthouses are highly rated for location, cleanliness, and more.
Vacation rentals for every style
Get the amount of space that is right for you.
Popular amenities for San Luis Obispo guesthouses
Family-friendly guesthouses

Romantic Canopy Goddess meets cowboy walk / town

Crooms Moonlight Ranch, Views and Amazing Sunsets!

Baywood Cottage, Private Garden

Bluebird Cottage

The Morro Road Casita

The Mermaid Cabin

Wine Country Bungalow w/ Pool, Spa

Private SLO Lodge: Gym, Sauna, Views, Wineries!
Guesthouses with a patio

Private top floor spacious 1 bedroom retreat

The Cozy Casita

The Shed

Maverick Bungalow

Deerfield Cottage on Paso's wine road

Central Coast Guest House - Private entrance

McClellan Cottage - centrally located studio

Casita By the Sea: Secluded and Serene
Guesthouse rentals with a washer and dryer

Renovated Private Hippy Beach Shack With Full Bath

Bright, Airy and Beautifully Built!

The Cottage - Serene garden/walk downtown & beach

Cedar Pines-Beautiful country getaway in the trees

Mesa View Ranch Avocados

Quiet Coastal-Valley Ranch Home

Historic 1919 carriage house

The Guesthouse
Quick stats about guesthouse rentals in San Luis Obispo
Total rentals
30 properties
Nightly prices starting at
$111 CAD before taxes and fees
Total number of reviews
5.5K reviews
Rentals with dedicated workspaces
10 properties have a dedicated workspace
Wifi availability
30 properties include access to wifi
Popular amenities
Kitchen, Wifi, and Pool
Destinations to explore
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- Rentals with beach access San Luis Obispo
- Rentals with an EV charger San Luis Obispo
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- Family-friendly rentals San Luis Obispo
- Rentals with a fireplace San Luis Obispo
- Cabin rentals San Luis Obispo
- Rentals with breakfast San Luis Obispo
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- Rentals with a patio San Luis Obispo
- Guesthouse rentals San Luis Obispo County
- Guesthouse rentals California
- Guesthouse rentals United States
- Cayucos Beach
- Moonstone Beach
- Montaña de Oro State Park
- Cayucos State Beach
- Natalie's Cove
- Hearst San Simeon State Park
- Morro Strand State Beach
- Mission San Luis Obispo de Tolosa
- Dairy Creek Golf Course
- B & E Vineyard & Winery
- Pismo State Beach
- Morro Rock Beach
- Bianchi Winery
- Pirates Cove Beach
- Olde Port Beach
- Seal Beach
- Paradise Beach
- Allegretto Wines
- Point Sal State Beach
- Au Bon Climat
- Morro Bay Golf Course
- Sand Dollars
- Baywood Park Beach
- Bovino Vineyards
- Things to do San Luis Obispo
- Things to do San Luis Obispo County
- Food and drink San Luis Obispo County
- Nature and outdoors San Luis Obispo County
- Things to do California
- Nature and outdoors California
- Wellness California
- Sightseeing California
- Art and culture California
- Food and drink California
- Sports activities California
- Entertainment California
- Tours California
- Things to do United States
- Tours United States
- Nature and outdoors United States
- Sightseeing United States
- Art and culture United States
- Food and drink United States
- Sports activities United States
- Entertainment United States
- Wellness United States