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Vacation rentals in Santa Maria

Find and book unique accommodations on Airbnb

Top-rated vacation rentals in Santa Maria

Guests agree: these stays are highly rated for location, cleanliness, and more.

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Guest favourite
A modern kitchen area features a granite island with two barstools and pendant lighting above. A stainless steel refrigerator and stove are visible, along with gray cabinetry. The living area includes a television set on a wooden stand, and a comfortable seating arrangement is present.
Condo in Mercedes
4.89 out of 5 average rating, 54 reviews

Peaceful spacious 3 bed condo by the outlets!

Centrally located in the Rio Grande Valley. This quiet 2 bedroom condominium is a shoppers paradise only two miles away from the Mercedes Outlets! Travel into the most tourist friendly border city in Mexico, the city of Progreso, only 10 miles away! Head to the beach at South Padre Island, about 50 miles away. Be mesmerized by Elon's Space X at Boca Chica Beach 67 miles away! Level 2 charging outlet (nema 14-50R) reserved for you, bring your own EV charger. Unlimited free parking on premises.

Top guest favourite
A spacious outdoor deck features wooden furniture, including a dining table with several chairs, offering views of the serene lake. The area is surrounded by lush greenery, with a hammock and a decorative trellis visible, enhancing the connection to nature.
Guesthouse in McAllen
4.97 out of 5 average rating, 301 reviews

Rm 101 Ethereal @ PeculiarNest Lake Conception

A beautiful lakefront one-bedroom cabin overlooking a 7-acre private lake and situated inside a one acre permaculture food forest/garden. It is a haven for birders and naturalists as well as the wildlife we share the space with. Enjoy feeding the roaming peacocks, viewing the sunrise and sunset, and sipping coffee on the private porch or pier. Additional units (apartment style&private rooms) are available to meet our guests' varying needs. Please check out my other listings in the profile.

Guest favourite
An open living space features a large sectional sofa adorned with decorative pillows. A staircase leads to an upper level, while a stylish chandelier hangs from the ceiling, illuminating the area. Dining and kitchen spaces are observable in the background.
Home in Mercedes
4.84 out of 5 average rating, 70 reviews

Cozy 4 bedroom home

🏡 Cozy Home Cozy, fully 4-bedroom, 2-bath home in the Mid Valley, just off the expwy. Located on the 2nd & 3rd floors (stairs required) with a private back entrance. The 1st floor is a separate business. Enjoy your morning coffee on the private balcony as the day begins. Inside, you’ll find a clean, comfortable space perfect for relaxing and gathering. Free parking in a well-lit carport. 📍 3 mins to Mercedes Outlets 📍 15 mins to McAllen Check-out: 10:00 AM $50/hr late check-out fee

Top guest favourite
The living area features two comfortable sofas adorned with yellow cushions, positioned around a round coffee table. A patterned area rug lies beneath, complementing the tiled floor. A ceiling fan is installed above, and natural light fills the space from the nearby dining area.
Home in Harlingen
5 out of 5 average rating, 141 reviews

Cozy Spacious 3BR Home w/King Bed/Near Airport

Welcome to our spacious three-bedroom, two-and-a-half-bath home located in the vibrant city of Harlingen, Texas! Nestled near the airport, our property offers both convenience and comfort, making it the perfect choice for your stay in the Rio Grande Valley. A short drive will take you to Brownsville, the stunning South Padre Island beckons with its pristine sandy shores, and Space X launch site, offering a unique opportunity to witness the marvels of modern space exploration up close.

Top guest favourite
Home in Edinburg
4.99 out of 5 average rating, 106 reviews

The Serene Home

Welcome to our Serene Home, where tranquility meets luxury for the ultimate escape. Nestled in the heart of Edinburg, this vacation home is a haven for those seeking a peaceful and rejuvenating gateway. The design blends Japanese with elements of zen-inspired architecture, creating a harmonious space that fosters relaxation. Natural light floods through large windows, illuminating the open living spaces. Embrace the serenity, and create lasting memories in this peaceful vacation home.

Guest favourite
A large outdoor swimming pool glimmers under a clear blue sky, surrounded by a wooden deck. Two lounge chairs are positioned beside the pool, and a wooden structure offers shaded seating. A dressing area with a large window and a privacy fence is visible in the background.
Condo in Mercedes
4.81 out of 5 average rating, 172 reviews

Newly remodeled condo w pool close to everything

This unique place has a style all its own. Enjoy your gateway in this fully stocked closed to everything! You will have access to a huge pool and an assigned private pergola with tv and fire pit! Condo is completely private with private entrance Backyard pool area is shared only with two other Airbnb units Perfectly located in the heart of the valley: 🛍 Just 3 minutes to the outlet mall 🌆 25 minutes to McAllen 🚗 15 minutes to Harlingen 🏖 50 minutes to South Padre Island

Guest favourite
Cabin in Donna
4.91 out of 5 average rating, 126 reviews

La Cabañita - ranch-style home

This unique place has a style all its own. La Cabañita is a 1 bedroom 1 bath modern ranch style home equipped with full kitchen, sofa bed, washer & dryer, and wi-fi for guests. La cabañita is in Donna, Tx. Just 1 min from the expressway. Conveniently located 15 minutes from La Plaza Mall in Mcallen Tx. as well as 15 minutes from Rio Grande Valley Premium Outlets in Mercedes, Tx. Property is completely fenced and parking will be within wooden fence for added privacy.

Guest favourite
The outdoor pool is illuminated in vibrant blue, creating a serene atmosphere. Surrounding the pool, a covered pergola features soft lighting and comfortable seating. The setting is enhanced by palm trees in the background, contributing to a relaxing outdoor space.
Guesthouse in Harlingen
4.84 out of 5 average rating, 212 reviews

Harlingen Guesthouse with a Pool

This place is a guesthouse located at the outskirts of Harlingen Texas. Very peaceful being it is out of city limits but still very close to restaurants, shopping etc. Just a 4 minute drive. You will have access to the pool and outdoor furniture as well as a charcoal grill. It is also a 45 minute drive to South Padre Island and 35 minute drive to the big city of Mcallen, Tx. and 15 minutes away from the outlets in Mercedes Tx.

Top guest favourite
The kitchen showcases wooden cabinetry and modern appliances, including a stainless steel refrigerator and oven. A small table with two chairs is positioned near the entrance. The space features tile flooring with a tiered step leading to the living area.
Guesthouse in Harlingen
4.99 out of 5 average rating, 108 reviews

Peaceful Country Getaway

This private, cozy guest house is next to our home and includes a bedroom, bathroom, full kitchen, and living room. It has a beautiful view of our 2.4 acre property. Amenities include a queen size bed, WiFi, refrigerator, oven, microwave, coffee maker and much more. Valley Baptist Medical Center–12 minutes Valley International Airport-15 minutes Brownsville–30 minutes McAllen–35 minutes South Padre Island–50 minutes

Guest favourite
The kitchen features modern cabinetry and sleek stainless steel appliances, including a refrigerator and microwave. A granite countertop offers ample space for meal preparation, complemented by bar seating for four. Natural light fills the area through large windows, creating a bright and inviting atmosphere.
Apartment in Weslaco
4.92 out of 5 average rating, 137 reviews

Modern comfortable retreat in gated community!

Minutes away from the outlet mall, the Progreso International bridge & much more. Perfectly located in the mid valley so you can decide if you want a beach day or a shopping day!! We welcome long term guests, medical visits, corporate visits etc. We want you to feel as comfortable as possible while you stay with us! Enjoy the best AirBNB experience available!

Guest favourite
Apartment in Harlingen
4.93 out of 5 average rating, 107 reviews

Fresh, Modern + Convenient Apartment

Indulge in the serenity of this exceptional apartment nestled in Harlingen, one of the Rio Grande Valley’s burgeoning locales. Whether you’re seeking a relaxing vacation close to numerous amenities or traveling for business with convenience in mind, this impeccably clean home offers the perfect retreat for any purpose.

Guest favourite
Home in Mercedes
4.92 out of 5 average rating, 59 reviews

Sleeps 10 | Game Room + Pool Table | Truck Parking

Restful and apacious 3BR/2BA home in Mercedes, TX — sleeps 10 for less than two hotel rooms. Built for families, work crews, nurses, and road-trippers exploring the Rio Grande Valley. Base rate covers up to 4 guests. Additional guests just $12/night — still a fraction of booking multiple hotel rooms.

Popular amenities for Santa Maria vacation rentals

  1. Airbnb
  2. United States
  3. Texas
  4. Cameron County
  5. Santa Maria