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Vacation rentals in Santa Maria

Find and book unique accommodations on Airbnb

Top-rated vacation rentals in Santa Maria

Guests agree: these stays are highly rated for location, cleanliness, and more.

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Guest favourite
A modern kitchen features a spacious island with three high-backed bar stools. The countertops are light-colored, complemented by dark cabinetry and a decorative backsplash. Stainless steel appliances are visible, and a small tray with flowers is placed on the island.
Condo in Mercedes
4.95 out of 5 average rating, 147 reviews

Quiet huge 4 bed condo 2 miles by the Outlets!

Centrally located in the Rio Grande Valley. This quiet 3 bedroom condominium is a shoppers paradise only two miles away from the Mercedes Outlets! Travel into the most tourist friendly border city in Mexico, the city of Progreso, only 10 miles away! Head to the beach at South Padre Island, about 50 miles away. Be mesmerized by Elon's Space X at Boca Chica Beach 67 miles away! Level 2 charging outlet (nema 14-50R) reserved for you, bring your own EV charger. Unlimited free parking on premises.

Superhost
A modern, single-story building features a combination of white and wood-paneled exteriors. Large black windows reflect natural light, and minimal landscaping with green grass and small shrubs surrounds the property, creating a welcoming atmosphere.
Apartment in Weslaco
4.86 out of 5 average rating, 66 reviews

Elegant Brand New Apartment in Weslaco

Elegant Serenity Apartment in Prime Weslaco Location Experience elegance in this brand-new, fully furnished Serenity-style apartment in the heart of Weslaco. Perfectly located just 15 minutes from McAllen and 30 minutes from Brownsville, enjoy easy access to major stores, HEB, Weslaco football stadium, and more. Designed with comfort and convenience in mind, this apartment has everything you need for a stylish and hassle-free stay. This property has hot water and all necessary equipment to cook

Top guest favourite
A small wooden pier extends over calm waters, flanked by trees and palmettos. Two white chairs are positioned beside softly glowing lamps, providing gentle illumination as the sun sets in the distance, creating a serene ambiance.
Guesthouse in McAllen
4.97 out of 5 average rating, 301 reviews

Rm 101 Ethereal @ PeculiarNest Lake Conception

A beautiful lakefront one-bedroom cabin overlooking a 7-acre private lake and situated inside a one acre permaculture food forest/garden. It is a haven for birders and naturalists as well as the wildlife we share the space with. Enjoy feeding the roaming peacocks, viewing the sunrise and sunset, and sipping coffee on the private porch or pier. Additional units (apartment style&private rooms) are available to meet our guests' varying needs. Please check out my other listings in the profile.

Guest favourite
Home in La Feria
5 out of 5 average rating, 15 reviews

Fully Stocked*Modern Luxury Retreat*King Bd*WD*BBQ

Ready for the perfect getaway? Relax in this fully stocked 2 bed 2 bath duplex. Conveniently located: Premium Outlets only 6 min; RGV Livestock Show 9min. ▶ Fully-equipped kitchen ▶ Washer/dryer ▶ Fast WiFi & adjustable desk ▶ Pack N Play/high chair ▶ 2 Free Driveway Parking Spots ▶ Comfy Nectar mattresses ▶ Pvt backyard (fully fenced) ▶ Newer appliances/furnishings Ideal for traveling professionals and snowbirds. Centrally located easy HWY access to Harlingen/McAllen. South Padre beaches 1hr.

Guest favourite
An open living space features a large sectional sofa adorned with decorative pillows. A staircase leads to an upper level, while a stylish chandelier hangs from the ceiling, illuminating the area. Dining and kitchen spaces are observable in the background.
Home in Mercedes
4.84 out of 5 average rating, 70 reviews

Cozy 4 bedroom home

🏡 Cozy Home Cozy, fully 4-bedroom, 2-bath home in the Mid Valley, just off the expwy. Located on the 2nd & 3rd floors (stairs required) with a private back entrance. The 1st floor is a separate business. Enjoy your morning coffee on the private balcony as the day begins. Inside, you’ll find a clean, comfortable space perfect for relaxing and gathering. Free parking in a well-lit carport. 📍 3 mins to Mercedes Outlets 📍 15 mins to McAllen Check-out: 10:00 AM $50/hr late check-out fee

Top guest favourite
An open living area features a spacious brown sectional sofa, accompanied by a coffee table, over a textured area rug. Large glass doors provide seamless access to the outdoor space, while modern pendant lights hang above a sleek kitchen island in the background.
Home in Edinburg
4.99 out of 5 average rating, 106 reviews

The Serene Home

Welcome to our Serene Home, where tranquility meets luxury for the ultimate escape. Nestled in the heart of Edinburg, this vacation home is a haven for those seeking a peaceful and rejuvenating gateway. The design blends Japanese with elements of zen-inspired architecture, creating a harmonious space that fosters relaxation. Natural light floods through large windows, illuminating the open living spaces. Embrace the serenity, and create lasting memories in this peaceful vacation home.

Guest favourite
A shared outdoor pool area is illuminated by string lights overhead, creating a relaxed evening ambiance. A float in the shape of a green alligator drifts on the water, while the pool's clear surface reflects the evening sky.
Condo in Mercedes
4.81 out of 5 average rating, 172 reviews

Newly remodeled condo w pool close to everything

This unique place has a style all its own. Enjoy your gateway in this fully stocked closed to everything! You will have access to a huge pool and an assigned private pergola with tv and fire pit! Condo is completely private with private entrance Backyard pool area is shared only with two other Airbnb units Perfectly located in the heart of the valley: 🛍 Just 3 minutes to the outlet mall 🌆 25 minutes to McAllen 🚗 15 minutes to Harlingen 🏖 50 minutes to South Padre Island

Top guest favourite
The kitchen showcases wooden cabinetry and modern appliances, including a stainless steel refrigerator and oven. A small table with two chairs is positioned near the entrance. The space features tile flooring with a tiered step leading to the living area.
Guesthouse in Harlingen
4.99 out of 5 average rating, 108 reviews

Peaceful Country Getaway

This private, cozy guest house is next to our home and includes a bedroom, bathroom, full kitchen, and living room. It has a beautiful view of our 2.4 acre property. Amenities include a queen size bed, WiFi, refrigerator, oven, microwave, coffee maker and much more. Valley Baptist Medical Center–12 minutes Valley International Airport-15 minutes Brownsville–30 minutes McAllen–35 minutes South Padre Island–50 minutes

Superhost
Home in Weslaco
5 out of 5 average rating, 3 reviews

4BR w/Pool and games

Spacious, fun-filled home perfect for families and groups! Enjoy a large living area with games like Monopoly, UNO, and a foosball table. Cook in a fully equipped kitchen or fire up the BBQ and dine outdoors. Relax in the large private pool with a kiddie pool for little ones. Located just 1 minute from Starbucks, McDonald’s, and Walmart—convenience at your doorstep!

Guest favourite
A spacious living area features a dark leather sectional sofa, paired with a sleek black recliner. Natural light fills the room through three windows, while a central coffee table stands between the seating. Decorative plants and modern light fixtures add a contemporary touch.
Apartment in Weslaco
4.92 out of 5 average rating, 137 reviews

Modern comfortable retreat in gated community!

Minutes away from the outlet mall, the Progreso International bridge & much more. Perfectly located in the mid valley so you can decide if you want a beach day or a shopping day!! We welcome long term guests, medical visits, corporate visits etc. We want you to feel as comfortable as possible while you stay with us! Enjoy the best AirBNB experience available!

Guest favourite
A dining area features a polished table set for four, complete with white dishware and glasses. Soft lighting is provided by a stylish chandelier overhead. A cozy living space is visible in the background, furnished with a couch and decorative accents, creating a harmonious atmosphere.
Apartment in Harlingen
4.93 out of 5 average rating, 107 reviews

Fresh, Modern + Convenient Apartment

Indulge in the serenity of this exceptional apartment nestled in Harlingen, one of the Rio Grande Valley’s burgeoning locales. Whether you’re seeking a relaxing vacation close to numerous amenities or traveling for business with convenience in mind, this impeccably clean home offers the perfect retreat for any purpose.

Top guest favourite
A living area features a large gray sofa and a two-seater couch, positioned across from a black entertainment unit with a television. Bright overhead lights illuminate the polished tile floor, while a dining area is visible in the background.
Home in Mercedes
4.95 out of 5 average rating, 77 reviews

Mid Valley Haven

Stay at a location close to everything in the Rio Grande Valley of Texas. The Premium Outlet Mall, the Rio Grande Live Stock Show Grounds, a border crossing to Mexico are all just minutes away. Centrally located to two hospitals (Knapp Medical Center and Valley Baptist Hospital).

Popular amenities for Santa Maria vacation rentals

  1. Airbnb
  2. United States
  3. Texas
  4. Cameron County
  5. Santa Maria