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Vacation rentals in Santa Maria

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Top-rated vacation rentals in Santa Maria

Guests agree: these stays are highly rated for location, cleanliness, and more.

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Guest favourite
A modern kitchen features a spacious island with three high-backed bar stools. The countertops are light-colored, complemented by dark cabinetry and a decorative backsplash. Stainless steel appliances are visible, and a small tray with flowers is placed on the island.
Condo in Mercedes
4.94 out of 5 average rating, 145 reviews

Quiet huge 4 bed condo 2 miles by the Outlets!

Centrally located in the Rio Grande Valley. This quiet 3 bedroom condominium is a shoppers paradise only two miles away from the Mercedes Outlets! Travel into the most tourist friendly border city in Mexico, the city of Progreso, only 10 miles away! Head to the beach at South Padre Island, about 50 miles away. Be mesmerized by Elon's Space X at Boca Chica Beach 67 miles away! Level 2 charging outlet (nema 14-50R) reserved for you, bring your own EV charger. Unlimited free parking on premises.

Top guest favourite
A small wooden pier extends over calm waters, flanked by trees and palmettos. Two white chairs are positioned beside softly glowing lamps, providing gentle illumination as the sun sets in the distance, creating a serene ambiance.
Guesthouse in McAllen
4.97 out of 5 average rating, 299 reviews

Rm 101 Ethereal @ PeculiarNest Lake Conception

A beautiful lakefront one-bedroom cabin overlooking a 7-acre private lake and situated inside a one acre permaculture food forest/garden. It is a haven for birders and naturalists as well as the wildlife we share the space with. Enjoy feeding the roaming peacocks, viewing the sunrise and sunset, and sipping coffee on the private porch or pier. Additional units (apartment style&private rooms) are available to meet our guests' varying needs. Please check out my other listings in the profile.

Top guest favourite
An open living area features a spacious brown sectional sofa, accompanied by a coffee table, over a textured area rug. Large glass doors provide seamless access to the outdoor space, while modern pendant lights hang above a sleek kitchen island in the background.
Home in Edinburg
4.99 out of 5 average rating, 105 reviews

The Serene Home

Welcome to our Serene Home, where tranquility meets luxury for the ultimate escape. Nestled in the heart of Edinburg, this vacation home is a haven for those seeking a peaceful and rejuvenating gateway. The design blends Japanese with elements of zen-inspired architecture, creating a harmonious space that fosters relaxation. Natural light floods through large windows, illuminating the open living spaces. Embrace the serenity, and create lasting memories in this peaceful vacation home.

Guest favourite
Home in Weslaco
5 out of 5 average rating, 12 reviews

NuSpace

Welcome to NuSpace, a modern 3-bedroom, 2-bath retreat in a quiet, established neighborhood. Sleeps six with one king and two queen beds. Enjoy the open layout, sunroom, fully equipped kitchen, and a backyard oasis with a courtyard, pecan tree, and BBQ area. Stay entertained with WiFi, Netflix, local cable, and Apple TV (log into your own apps). Perfect for families, friends, or business travelers seeking comfort, space, and a touch of tranquility.

Top guest favourite
A single-story home featuring a brick façade and a manicured front yard. Two palm trees stand nearby, while a concrete driveway accommodates multiple vehicles. Windows are framed by greenery, creating a welcoming exterior view under a partly cloudy sky.
Home in Weslaco
4.94 out of 5 average rating, 154 reviews

My House

Mi Casa Tu Casa Weslaco Tx, a small city that has everything. Enjoy every moment in this home that is made especially for you!.. 16 Minutes to Progreso bridge (Progreso México) 16 Minutes to Donna bridge (México Rio bravo) 31 Minutes to Valley International Airport (Harlingen tx) 23 Minutes to Mcallen International Airport and Plaza Mall 13 Minutes to Rio grande Valley Premium Outlet 6 Min from 83 Hwy 1:12 Min to south Padre island via 1-2

Guest favourite
A charming guesthouse exterior is framed by a neat garden bed featuring potted plants and decorative stones. The well-maintained pathway leads to a welcoming door, complemented by two windows that allow natural light to fill the interior spaces.
Guesthouse in Harlingen
4.84 out of 5 average rating, 211 reviews

Harlingen Guesthouse with a Pool

This place is a guesthouse located at the outskirts of Harlingen Texas. Very peaceful being it is out of city limits but still very close to restaurants, shopping etc. Just a 4 minute drive. You will have access to the pool and outdoor furniture as well as a charcoal grill. It is also a 45 minute drive to South Padre Island and 35 minute drive to the big city of Mcallen, Tx. and 15 minutes away from the outlets in Mercedes Tx.

Top guest favourite
A welcoming living room features a blue sofa with decorative pillows, flanked by two wooden side tables holding lamps. A neutral-colored area rug lies beneath a wooden coffee table, surrounded by a plush armchair and two textured poufs, while soft light fills the spacious area.
Guesthouse in Harlingen
4.99 out of 5 average rating, 106 reviews

Peaceful Country Getaway

This private, cozy guest house is next to our home and includes a bedroom, bathroom, full kitchen, and living room. It has a beautiful view of our 2.4 acre property. Amenities include a queen size bed, WiFi, refrigerator, oven, microwave, coffee maker and much more. Valley Baptist Medical Center–12 minutes Valley International Airport-15 minutes Brownsville–30 minutes McAllen–35 minutes South Padre Island–50 minutes

Guest favourite
A cozy bedroom is equipped with a spacious bed dressed in a patterned gray and white quilt. A ceiling fan with wooden blades provides ventilation. Natural light enters through a window covered by a dark curtain. A side table with a lamp and decorations is also present.
Apartment in Harlingen
4.96 out of 5 average rating, 106 reviews

Lovely 1bed/1bath apartment

This apartment is located 5-10 minutes to the airport, local grocery stores, shopping centers, hospitals, and highway. Rio Grande Valley Premium Outlet shopping center is around 15 minutes away in Mercedes, Tx. McAllen and Edinburg will take you around 35-40 minutes. If you’d like to visit the beach, South Padre Island is around 45-60 minuets away. Please make contact with me if you have any questions.

Guest favourite
Home in Mercedes
4.9 out of 5 average rating, 166 reviews

Shop, swim, & relax private pool 3 min to outlets

Private pool Newly remodeled and furnished ready to make your stay as comfortable and convenient as possible! right off the expressway across from the outlet mall 3 minute drive) , 20 minutes away from McAllen, and 40 minutes away from South Padre Island! 5 minutes away from stock show grounds. Home sits on 1/2 acre in a quiet and peaceful neighborhood! 2 queen beds 2 twin beds Fold out sofa

Guest favourite
Home in Mercedes
4.91 out of 5 average rating, 57 reviews

Sleeps 10 | Game Room + Pool Table | Truck Parking

Restful and apacious 3BR/2BA home in Mercedes, TX — sleeps 10 for less than two hotel rooms. Built for families, work crews, nurses, and road-trippers exploring the Rio Grande Valley. Base rate covers up to 4 guests. Additional guests just $12/night — still a fraction of booking multiple hotel rooms.

Guest favourite
Apartment in Weslaco
5 out of 5 average rating, 10 reviews

Executive Suite

Enjoy your private suite designed for comfort and productivity. Enjoy two full bathrooms, a private office for remote work, and a stylish open living space ideal for short or extended stays. Perfect for professionals seeking peace, privacy, and convenience. It's a four-minute drive to the expressway.

Top guest favourite
A living area features a large gray sofa and a two-seater couch, positioned across from a black entertainment unit with a television. Bright overhead lights illuminate the polished tile floor, while a dining area is visible in the background.
Home in Mercedes
4.95 out of 5 average rating, 75 reviews

Mid Valley Haven

Stay at a location close to everything in the Rio Grande Valley of Texas. The Premium Outlet Mall, the Rio Grande Live Stock Show Grounds, a border crossing to Mexico are all just minutes away. Centrally located to two hospitals (Knapp Medical Center and Valley Baptist Hospital).

Popular amenities for Santa Maria vacation rentals

  1. Airbnb
  2. United States
  3. Texas
  4. Cameron County
  5. Santa Maria