
Vacation rentals in Santee River
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Top-rated vacation rentals in Santee River
Guests agree: these stays are highly rated for location, cleanliness, and more.
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Vacation rentals for every style
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Popular amenities for Santee River vacation rentals
Other great vacation rentals in Santee River
Top guest favourite

Home in Ridgeville
5 out of 5 average rating, 44 reviewsRiverfront Stay w/ Dock + Kayaks – Pet Friendly
Guest favourite

Home in Andrews
4.86 out of 5 average rating, 22 reviewsSpacious 3-Bed Home w/ Deck
Top guest favourite

Guesthouse in Summerville
5 out of 5 average rating, 48 reviews2 King beds 2 Bath*Gardens* Downtown Summerville
Top guest favourite

Cabin in Summerville
4.97 out of 5 average rating, 37 reviewsThe Cabin at Cool Blow Farms
Guest favourite

Home in Summerton
5 out of 5 average rating, 11 reviewsSunset Serenity Pool/Swim Spa
Top guest favourite

Cottage in McClellanville
4.95 out of 5 average rating, 58 reviewsLove Shack 1 bedroom cottage on 12 acre farm
Top guest favourite

Apartment in Moncks Corner
5 out of 5 average rating, 22 reviewsCozy escape studio apartment
Guest favourite

Home in Eutawville
4.96 out of 5 average rating, 73 reviewsHeated Indoor Pool on Lake Marion with Dock
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- Park Circle
- Huntington Beach State Park
- Sullivan's Island Beach
- Bulls Island
- Garden City Beach
- Magnolia Beach
- Middleton Place
- The Golf Club at Wescott Plantation
- Waterfront Park
- Shem Creek Park
- James Island County Park
- Angel Oak Tree
- Caledonia Golf & Fish Club
- Hampton Park
- The Charleston Museum
- Sandy Point Beach
- Isle of Palms Beach
- Morris Island Lighthouse
- White Point Garden
- Debidue Beach
- Charleston Aqua Park
- Gibbes Museum of Art
- Litchfield Beach and Golf Resort
- Splash Zone Waterpark At James Island County Park