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House vacation rentals in Santo Domingo

Find and book unique houses on Airbnb

Quick stats about house rentals in Santo Domingo

  • Total vacation rentals

    Explore 470 vacation rentals in Santo Domingo

  • Nightly prices starting at

    Santo Domingo vacation rentals start at $14 CAD per night before taxes and fees

  • Verified guest reviews

    Over 13,960 verified reviews to help you choose

  • Family-friendly vacation rentals

    190 properties offer extra space and kid-friendly amenities

  • Pet-friendly vacation rentals

    Find 120 rentals that welcome pets

  • Vacation rentals with a pool

    90 properties feature pools

  • Rentals with dedicated workspaces

    180 properties have a dedicated workspace

  • Wifi availability

    440 of Santo Domingo vacation rentals include wifi access

  • Popular amenities for guests

    Guests love Kitchen, Wifi, and Pool across Santo Domingo rentals

  • 4.7 Average rating

    Santo Domingo stays receive an average rating of 4.7 out of 5 from guests

Top-rated house rentals in Santo Domingo

Guests agree: these houses are highly rated for location, cleanliness, and more.

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Guest favourite
A welcoming living area features a comfortable wooden sofa adorned with green cushions, accompanied by two wooden chairs. A round wooden coffee table is centered on a patterned blue and white rug, while a potted plant adds a touch of greenery near a window.
Home in Ciudad Colonial

New - 3 Bd House Zona Colonial + Private Rooftop

🌴🥥 Welcome to the perfect oasis in the Dominican Republic. We are so happy to host you ! We are centrally located in La Zona Colonial, the historic central neighborhood of the Dominican Republic's capital, Santo Domingo. It is the oldest continuously inhabited European-established settlement in the Americas. We are steps away from restaurants, night life, bars, museums and landmarks. Casa Altagracia is an eclectic, unique and curated house welcoming families, couples and friends.

FamilyValueIndoor spaces

4.84 out of 5 average rating, 173 reviews
Top guest favourite
A spacious outdoor patio area is surrounded by tall trees and lush greenery. Seating is provided by white lounge chairs and a sofa. A gas BBQ grill is positioned in one corner, and potted plants add a touch of nature to the serene setting.
Home in Los Prados

Casa Serena: Made for Family & Friends

Welcome to Casa Serena! Enjoy Santo Domingo with the comfort and privacy of an entire home. Ideal for families traveling from abroad to visit relatives and friends, and for groups coming for celebrations, work, or other activities. Up to 10 guests, 4 bedrooms, spacious areas to gather, a fully equipped kitchen, and a cozy patio. Located in La Castellana, a central and easily accessible area in a quiet residential neighborhood. A place to relax, spend time together, and feel at home.

FamilyValueParking

4.99 out of 5 average rating, 151 reviews
Guest favourite
Home in Ciudad Colonial

Casa del Orfebre, circa 1525

Welcome to Casa del Orfebre, a jewel from the past, where history comes alive and the charm of the 16th century is breathed in every corner. This antique house, meticulously restored and consolidated, is located in the heart of the Colonial City and is one of the historical buildings certified by the colonial heritage of Santo Domingo, declared a World Heritage Site by UNESCO. 3 rooms have queen beds and 1 room with 2 double beds. So for 10 guests it is a perfect accommodation.

ValueFamilyAmenities

4.94 out of 5 average rating, 47 reviews
Guest favourite
Home in Ciudad Colonial

Modern apartment in the Colonial City

Exclusive apartment in the Colonial City of Santo Domingo, ideal for those seeking history, comfort and a unique experience. Located in one of the city's most iconic areas, this elegant space combines colonial charm with modern comforts. It has one bedroom, a spacious and bright living room, and a fully equipped kitchen. Its biggest draw is a spectacular private terrace with a hot tub, perfect for relaxing and enjoying the Caribbean climate.

ValueLocationWalkability

5.0 out of 5 average rating, 15 reviews
Guest favourite
A bright and airy entrance leads to a serene outdoor area with a pool. The space is framed by modern glass walls, showcasing inviting seating and greenery. Natural light filters through, enhancing the layout that connects indoor and outdoor living.
Home in Ciudad Colonial

Stunning villa in Zona Colonial

Casa Republic – Historic Charm, Modern Luxury Tucked away in Santo Domingo’s iconic Zona Colonial, Casa Republic is a 4-suite architectural gem where colonial heritage meets contemporary design. Cool off in your private pool, unwind on the rooftop terrace, or relax in elegant indoor-outdoor spaces crafted for comfort and style. With room for up to 8 guests, this one-of-a-kind home offers a refined retreat in the charm of the old city.

LocationValueGetting around

4.94 out of 5 average rating, 65 reviews
Guest favourite
The living area features a light blue sofa paired with a small neutral-toned coffee table. A colorful piece of wall art hangs above the sofa, and a dining table is visible in the corner. A ceiling fan and green curtains enhance the space, while natural light enters from a nearby window.
Home in Santo Domingo

Cozy, central and well-equipped place

We are located in a central and quiet part of the city, with access to 27 de Febrero, Máximo Gómez, and Jhon F. Kennedy avenues. Nearby are the Ibero-American University (Uníbe), Zambil shopping center, Banco Popular Dominicano Tower, as well as pharmacies and health centers. The apartment is located on the first floor, with independent access, parking, and an electric gate. It has a cable system, high-speed WiFi, and an inverter.

ValueLocationAccess

4.94 out of 5 average rating, 173 reviews
Top guest favourite
A covered terrace features a wooden floor, surrounded by potted plants. Four chairs with colorful cushions face a wooden table. A hammock and a cozy blue chair are positioned nearby, with an open view of the rooftops in the background.
Home in Ciudad Colonial

Charming Old City Corner House

This charming 2 bedroom corner house is located in the walled colonial city of Santo Domingo. It’s only a few steps away from historical attractions, museums, restaurants, coffee shops, bars, souvenir shops, bakeries, supermarket and lovely squares. The beautiful covered terrace, overlooking the rooftops of the old town with living area, hammock and BBQ is perfect for a relaxing afternoon or evening.

ValueLocationLong stay

4.96 out of 5 average rating, 116 reviews
Guest favourite
A bright living area features a comfortable sofa adorned with decorative pillows and a coffee table. Natural light filters through large windows, highlighting the outdoor greenery. A ceiling fan provides airflow, and the entrance door opens to a welcoming patio space.
Home in Ensanche Alma Rosa

Spacious house, gated community of Alma Rosa I

This house is located in a closed and very safe residential area. It is centrally located; only 20 minutes from the airport of Las Americas and a few minutes from the most iconic places in the great Santo Domingo. You can also walk to the restaurants, supermarket and shopping centres in the area. We offer check- in early and late check-out, according to the reservations we have pending.

FamilyLocationAccess

4.81 out of 5 average rating, 145 reviews
Top guest favourite
A two-story building is depicted, featuring a light-colored exterior and a pop of blue accents. The lower level includes a planter box and secured entrances. A person rides a bicycle nearby, adding a sense of activity to the quiet street setting adorned with plants.
Home in Ciudad Colonial

Heart of the colonial zone, Billini 54

At the very heart of the most exclusive part of the colonial city where all the fun and interesting activities take place. This beautiful one-bedroom apartment is on the first floor of a small building next to the colonial gate 4D cinema, electric bike rentals, beer market, food markets, historical landmarks, exclusive boutiques, galleries, restaurants and bars.

ValueFamilyLaundry

4.88 out of 5 average rating, 341 reviews
Guest favourite
A modern living area features two armchairs in rose color opposite a sleek marble coffee table. A television is mounted on the wall, and light filters through sheer curtains, illuminating the space. Decorative elements include a vase of flowers on the side table.
Home in Santo Domingo de Guzman

Cozy & Beautiful City Center House with Jacuzzi

The House is located in " El Cacique", one of the safest areas in the city, with access to Malecón ( Caribbean Sea), supermarket and clinics 5 minutes walk, access to Mirador Sur park, and 15-20 minutes from the most prestigious shopping centers in the city. Located approximately 40 minutes from the airport and 14 minutes from Zona Colonial.

FamilyValueCheckout

4.95 out of 5 average rating, 153 reviews
Guest favourite
Home in Santo Domingo Este

Luxury house in the East Zone

Spacious luxury house with 2 levels, ideal for being with a partner, friends or family. It has all the necessary amenities for a pleasant and luxurious stay. Located in the eastern area, 15 minutes from Las Américas Airport. 2 minutes from Bravo Avenida Hípica and 5 minutes from Avenida Ecológica.

LocationFamilyLong stay

4.95 out of 5 average rating, 119 reviews
Superhost
Home in Santo Domingo Este

Elegant Villa with Private Pool | Casa #8

Enjoy an unforgettable stay in this modern two-storey villa, designed to offer comfort, privacy and an elegant atmosphere. Located just 15 minutes from Las Américas International Airport (SDQ), it is the perfect place for vacations, family trips, weekend getaways or business stays.

CleanlinessPoolIndoor spaces

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