
Vacation rentals in Seneca
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Top-rated vacation rentals in Seneca
Guests agree: these stays are highly rated for location, cleanliness, and more.

Treehouse at Keowee Hollow
Welcome to the treehouse at Keowee Hollow!!! A CHARMING space nestled in a hollow - with a view of Lake Keowee - perfect for a ROMANTIC getaway or a peaceful retreat. This COZY, brand new, 1 bedroom, 1 bath treehouse offers rest and relaxation. Perfect location. We are minutes from Seneca, 10 miles from Clemson, under an hour to downtown Greenville, Highlands or Cashiers. The outdoor seating area is a perfect place to unwind at the end of a busy day, also features a fire pit & outdoor grill.

Destination Keowee
A rustic industrial style Lake Keowee lakefront escape that places you right on a panoramic point in a private cove. Welcome the outdoors in with the 6ft kitchen hinge bar window to the upper deck or enjoy the 6-seat hot tub on lower deck. Deep water dock tie off space is available. Guests enjoy the use of 2 standup paddle boards, and lakeside fire pit (guest provide firewood). Great cove sunsets! 15 minutes to Clemson and 1 min Lighthouse Restaurant. Please read all details prior to booking!

Modern Lake Vibes – Kayaks, Dock & Fireplace
The perfect home for lake lovers and college football fans. Located just ~5 minutes away from Clemson and Death Valley, the newly renovated lakefront cottage will be the perfect stay for you, your family, and friends. With an outdoor fire pit, amazing views, boat dock, kayaks, and a modern kitchen, this retreat has all the amenities you're looking for inside and out! Whether you spend your time relaxing at the house, cheering on the Tigers, or fishing the lake, the Hideaway is sure to please.

Farm Geodome Near Lake Jocassee, Hot Tub, Zip Line
Glamping: where luxury meets the outdoors. This geodesic structure offers a rare opportunity to experience the outdoors without the elements. Complete with kitchen, AC & heat, dual control heated mattress pad, fully functioning bathroom, and sunrise views over the pasture. Whether you are looking to relax and enjoy feeding the farm animals, have an adventure riding the zip line, or indulge in a romantic evening sipping wine in the hot tub under the stars, you will leave with lasting memories.

The Wildflower
Enjoy a relaxing experience at this centrally-located spot, away from the hustle and bustle but only 6 min from Clemson (10 min from Clemson University), nestled in the country in a peaceful, safe neighborhood with lots of privacy surrounding. The cottage has a front porch with 2 chairs, a 2 person hammock, grill, and a fire pit (wood is provided) with three lawn chairs. There’s a queen bed and also a CordaRoy beanbag (*bed #2) that opens up to a soft bed that sleeps 1 adult or two children.

THE BELLA LUNA Romantic Treehouse - Outdoor Shower
This is the perfect ROMANTIC ESCAPE! Located in the Sumter National Forest the Bella Luna is just 5 minutes from Stumphouse Tunnel, Issaqueena Falls, Yellow Branch Falls hiking trail, and Stumphouse Mountain Bike Park and within an hour of Clemson, Lake Jocassee and Clayton, GA. Our romantic retreat features carefully curated vintage furnishings, an outdoor shower, napping net, relaxing seating areas and an outdoor fire pit stocked with firewood and a S’mores kit! We can't wait to host you!

Clemson Mom Apartment
Roomy 1 bedroom, 1 bath apartment in Seneca, SC. Approximately 2.5 miles from Wal-Mart and 2 miles from Waffle House. 9 miles from Clemson football stadium. Excellent location with a short drive to restaurants, shopping, 3 24-hour gyms, and grocery stores. Located in a quiet subdivision with minimal traffic. This is the perfect spot, close to Seneca, but away from highly trafficked areas. Great for a working adult and quiet enough during the day for someone working third shift to sleep.

Cozy Lake House 5 miles from Clemson w Dock
Only 5 miles from Clemson's campus, this retreat is perfectly situated on almost a full acre. You’ll love the cozy feel, with lots of amenities, including a well stocked kitchen, three-season screened-in porch, & open floor plan. Though the house isn’t directly on the water, our private dock on Hartwell is only a 1-2 min walk away! Nestled between Greenville and the mountains, this home is great for Clemson trips, lake adventures, close night life, restaurants, family entertainment, & more!

Cottage in the Country w/ Hot Tub/12mi to Clemson
Relax and unwind at our custom built cottage that provides a peaceful space perfect for 2. This cozy retreat is nestled in the woods in a country setting and offers a deck and hot tub to enjoy the beauty of nature. A dedicated work space is also provided if you're here for work or looking for a place for solitude. It's located only 5 miles from Seneca, 12 miles from Clemson, and 40 miles from Greenville and is a short drive as well to beautiful lakes, waterfalls, and hiking trails.

Oak Hill Getaway
Right between Seneca and Clemson you will find our getaway. It's 5 mins from Historic Ram Cat Alley with shopping, restaurants, and breweries with Jazz on the Alley music every Thursday night (April - Oct.) It's only 10 minutes from Clemson University. Surrounded by 3 different lakes Jocassee, Keowee, and Hartwell with just a short drive away. You can ride 30 mins up to the mountains where you can hike trails and see waterfalls the foothills have to offer.

The Cottage
Relax, recharge, and enjoy the quiet. Unwind on the front porch as the sun sets and nature comes alive with the peaceful sounds of evening. Spend time by the pond and cast a line for a simple, relaxing escape (fishing poles not provided). Private and serene, yet just 5 minutes to Walmart and Oconee Memorial Hospital—and only 13 miles to Clemson. The perfect blend of tranquility and convenience. Minimum age to book is 25 years of age.

Tiny house
BRAND NEW 490 sq ft tiny house/cottage nestled in the woods in a country setting. Complete with a queen bedroom, a twin/day bed and then a queen bed in loft ( comfortably sleeps 4 adults and one child). We are conveniently located 10 miles from I-85 exit 1 on S Hwy 11. 20 minutes from Clemson, 8 minutes from Seneca, and just a short drive to many hiking trails, lakes and parks in the beautiful foothills of the Blue Ridge mountains.
Popular amenities for Seneca vacation rentals
Stay near Seneca's top sights
Other great vacation rentals in Seneca

The Cottage upper level

Hearth & Pine Cottage | Cozy Nature Escape

Little Blue Lake House | Minutes from CU

Lakefront Mid-Century Dream Home / 3 mi to Clemson

Lovely 2-bedroom apartment in welcoming Seneca

New! Charming 4/2.5 Modern Home in Clemson, SC

South Cove Cottage ~ Lake Keowee

Hartwell Hideway
When is the best time to visit Seneca?
| Month | Jan | Feb | Mar | Apr | May | Jun | Jul | Aug | Sep | Oct | Nov | Dec |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Avg. price | $211 CAD | $255 CAD | $236 CAD | $218 CAD | $283 CAD | $235 CAD | $263 CAD | $331 CAD | $319 CAD | $275 CAD | $319 CAD | $253 CAD |
| Avg. temp | 6 °C | 8 °C | 12 °C | 16 °C | 21 °C | 25 °C | 27 °C | 26 °C | 23 °C | 17 °C | 11 °C | 7 °C |
Frequently Asked Questions
What are the best things to do in Seneca with kids?
Families can explore local parks, visit playgrounds, or enjoy time by Lake Keowee for swimming and picnics. Educational centers, walking trails, and family-friendly events around town are also frequently suggested.
What are some of the best things to do in Seneca?
Explore Historic Downtown’s boutiques and cafes, relax at Lake Keowee, or visit nearby state parks for hiking and outdoor recreation. Community festivals and farmers markets also add a local touch throughout the year.
How is the weather in Seneca?
Seneca has mild winters around 33–53°F (1–12°C) and warm, humid summers that reach 90°F (32°C). Rain is spread throughout the year, so it is helpful to bring layers and a rain jacket for outdoor plans.
When is the best time to visit Seneca?
Late spring and early autumn are often recommended for comfortable temperatures and colorful scenery. Summer is popular for lake activities, while spring brings local events and blooming landscapes.
What are the best places to visit in Seneca?
Explore Lake Keowee’s shores, browse Historic Downtown’s local shops, or head to South Cove County Park for picnic spots and waterfront access. Cultural centers and museums around town are also frequently suggested.
What are some hiking trails in Seneca?
You will find walking and hiking paths in South Cove County Park and around Lake Keowee. For more variety, nearby state parks are known for scenic trails suitable for most experience levels.
What are some family activities we can do in Seneca?
Families can picnic at local parks, swim or paddle on Lake Keowee, and explore interactive exhibits in community centers. Seasonal festivals and farmers markets often host games, music, and family-friendly vendors.
What are some of the best day trip ideas from Seneca?
Visitors frequently explore nearby state parks for hiking and waterfalls, check out upstate art towns, or tour local vineyards and orchards. Lakes, historic sites, and mountain views are also within easy reach for a full day’s adventure.
Are there any pet friendly accommodations available in Seneca?
Many places in and around Seneca welcome pets, especially those near Lake Keowee or set in rural surroundings. It is helpful to check individual listings for rules on pets and any special amenities, such as fenced yards or easy trail access.
What are some local tips for visiting Seneca?
Try the weekly farmers market for local produce and crafts, and enjoy the lake early or late in the day for quieter moments. Locals appreciate layered clothing due to changing weather and recommend checking for community events during your stay.
What is Seneca known for?
Seneca has a lively lakeside community centered around Lake Keowee, a revitalized Historic Downtown, and access to outdoor recreation in the foothills of the Blue Ridge Mountains. Community events and historic sites reflect the area’s local traditions.
What are the best hidden gems to explore in Seneca?
Many visitors enjoy lesser-known parks, local art galleries, and specialty shops tucked away in Historic Downtown. Quiet coves along Lake Keowee and nearby heritage museums also draw those seeking unique local experiences.
What are the best foods to try in Seneca?
Seneca has locally rooted Southern cuisine, with dishes like barbecue, fried catfish, and homemade pies often recommended. Seasonal farmers markets around the area feature regional produce and handmade treats during parts of the year.
What should I bring for a trip to Seneca?
Pack layers for changing temperatures, a rain jacket for unexpected showers, and comfortable shoes for outdoor activities. A swimsuit, sun protection, and reusable water bottle are helpful for time by the lakeshore or on trails.
What is the nightlife in Seneca like?
Seneca’s nightlife features casual bars, local pubs, and live music venues around Historic Downtown. Events and open-air concerts bring residents and visitors together during warmer months.
What are the most popular events or festivals in Seneca?
Seneca hosts seasonal festivals, including downtown music events, local fairs, and outdoor concerts, especially in the warmer months. Community celebrations around Memorial Day and late spring are frequently highlighted by locals.
Are there family friendly vacation rentals in Seneca?
Seneca has a range of family-friendly rentals, including lakefront homes and properties in quiet residential neighborhoods. Many include amenities such as full kitchens, multiple bedrooms, and outdoor spaces for children to play.
What are the best places to stay in Seneca?
Travelers often stay near Lake Keowee for access to water activities, Historic Downtown for local shops and restaurants, or in the countryside for a quieter experience. Many homes and apartments in these areas welcome visitors looking for both relaxation and recreation.
Quick stats about vacation rentals in Seneca

Total vacation rentals
Explore 70 vacation rentals in Seneca

Nightly prices starting at
Seneca vacation rentals start at $71 CAD per night before taxes and fees

Verified guest reviews
Over 2,520 verified reviews to help you choose

Family-friendly vacation rentals
50 properties offer extra space and kid-friendly amenities

Pet-friendly vacation rentals
Find 20 rentals that welcome pets

Rentals with dedicated workspaces
20 properties have a dedicated workspace

Wifi availability
70 of Seneca vacation rentals include wifi access

Popular amenities for guests
Guests love Gym, BBQ grill, and Laptop-friendly workspace across Seneca rentals

4.9 Average rating
Seneca stays are highly rated by guests—averaging 4.9 out of 5!
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