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Vacation rentals in Seneca

Vacation rentals in Seneca

Find and book unique accommodations on Airbnb

Top-rated vacation rentals in Seneca

Guests agree: these stays are highly rated for location, cleanliness, and more.

  • Charming Condo Lakefront
    Entire condominium · 8 guests · 3 beds · 2.5 baths
    Charming Condo Lakefront

    Unbelievable water front condo on Lake Keowee perfect for a fun-filled family summer vacation. This 3 bedroom 2.5 bath condo is conveniently located to historical downtown Seneca, shopping, and only minutes away from Clemson University.

    What guests are saying:

    “The condo is amazing... it's waterfront to lake keowee and we had a dockside area to park the boat. Fantastic weekend. Grocery store is a few minutes away, marina with small restaurant and bar along with other restaurant choices all within an easy few minutes drive. We brought in our own food and drinks pretty much stayed right there enjoying the boat on the water and the condo. Plenty of space to enjoy visiting, beds are comfy.”

  • Lake Keowee, SC Vacation Home, up to 14 guests!
    SUPERHOSTEntire house · 14 guests · 8 beds · 3 baths
    Lake Keowee, SC Vacation Home, up to 14 guests!

    Come visit the sunny South any time of the year in a lovely 5 bedroom, 3 bath home! This home was just bought and completely decked out in all new furniture, grill, linens-everything is new! Accommodations and a kitchen actually stocked to cook and serve the up to 14 guests who will be enjoying the lake, mountains, waterfalls, hiking, fishing, boating or just relaxing on the deck, dock, patio or in the 2 large dens with cable-connected TV's. Short and long term rentals are available.

    What guests are saying:

    “Tyler’s lake house is a perfect spot on the lake in a quiet cove. Lake Keowee is a large, deep, fun lake to explore. There is also nearby hiking. The boat dock is very nice and we were able to park our boat under the covered awning. There is a boat ramp nearby at South Cove Park. Everything was clean and in good condition. Our kids took over the two rooms on the lower level where there was a large living space and ping pong. The master suite is beyond expectations. The other two rooms on the main floor are adequate and nice. All mattresses were comfortable. The porches were spacious and great for looking out over the lake. Thanks Tyler! We hope to be back!”

  • Tee House... waterfront on beautiful Lake Keowee
    SUPERHOSTEntire house · 8 guests · 4 beds · 4 baths
    Tee House... waterfront on beautiful Lake Keowee

    Charming Traditional brick home nestled on beautiful Lake Keowee.. Dock on deep water,perfect for water sports,fishing,just enjoying the view. Kayaks, paddle boat,canoe, paddles ,life jackets are available for your enjoyment.. Massive decks ,Gas grill,Home has 4 bedrooms.. 2 kings, 2 queen, a queen air mattress,4 baths Location is a must. Minutes to Clemson Death Valley,for all college sports.Enjoy a short walk or drive to Keowee Marina, have lunch at the TIKI HUT or rent a boat for the day!

    What guests are saying:

    “My family and I had a great stay! Plenty of room for the 7 of us. The short walk down to the lake and easy access to the canoe and kayaks was a huge plus. Beautiful views of Lake Keowee with plenty of deck space to enjoy time outside. Theresa was a great host and really took the time to make us feel welcome, including complimentary coffee and snacks.”

Vacation rentals for every style

Get the amount of space that is right for you.

  • Homes
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Popular amenities for Seneca vacation rentals

  • Kitchen
  • Wifi
  • Pool
  • Free parking on premises
  • Air conditioning

Other great vacation rentals in Seneca

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Entire house
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Price:$129 CAD/night
Blue Cottage Studio
SUPERHOSTPrivate room
Blue Cottage Studio
Price:$61 CAD/night
Lakefront Cabin Lake Hartwell *Hot Tub Dock Kayaks
SUPERHOSTEntire cabin
Lakefront Cabin Lake Hartwell *Hot Tub Dock Kayaks
Price:$184 CAD/night
The Blue Room with Private Entrance
SUPERHOSTPrivate room
The Blue Room with Private Entrance
Price:$66 CAD/night
The Cottage - Entire Upper Level/Apt 2 BR  plus
Entire cottage
The Cottage - Entire Upper Level/Apt 2 BR plus
Price:$203 CAD/night
Clemson Mom Apartment
SUPERHOSTEntire apartment
Clemson Mom Apartment
Price:$69 CAD/night
THE MAJESTIC TREEHOUSE romantic, luxury retreat
SUPERHOSTTreehouse
THE MAJESTIC TREEHOUSE romantic, luxury retreat
Price:$598 CAD/night
Friendly, comfortable home
SUPERHOSTPrivate room
Friendly, comfortable home
Price:$46 CAD/night
Lit'l Bit O' Heaven- Rocky Top Lodge
SUPERHOSTEntire guesthouse
Lit'l Bit O' Heaven- Rocky Top Lodge
Price:$134 CAD/night
Elfwing Carriage House
SUPERHOSTEntire guest suite
Elfwing Carriage House
Price:$102 CAD/night
Mountain Rest Last Resort at Lake Becky
SUPERHOSTEntire cabin
Mountain Rest Last Resort at Lake Becky
Price:$115 CAD/night
Private Rooms, Superb Location, Generous Amenities
SUPERHOSTPrivate room
Private Rooms, Superb Location, Generous Amenities
Price:$66 CAD/night
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