
Vacation home accommodations in South America
Find and book unique vacation houses on Airbnb
Top-rated vacation houses in South America
Guests agree: these vacation houses are highly rated for location, cleanliness, and more.
Vacation rentals for every style
Get the amount of space that is right for you.
Popular amenities for South America vacation houses
Family-friendly vacation houses

Modern studio apartament close to the beach (4)

Apartment Palermo soho excellent location!

Eco Cabin with Sky Views - Organic Farm

Gated Comunity, 6 Pools, Walk to the Beach or Town

Nice and bright apartment in Barrio Bellavista

Spotless 2BR/2BA in Lastarria, Safe and Secure

Central location for different tourist spots

Zion’s House - Dreamy Surf Beachfront
Vacation home rentals with a patio

A peaceful place in the Patagonian steppe

3 Bedroom Sunset penthouse private jacuzzi

Amazing unobstructed ocean view

25flr Luxury Retreat @Infinitum/Bocagrande

Cepilho's house

Bungalows Drie 1 ~A/C ~Great Location

7th Heaven · 2 Terraces · Panoramic View · +Wi-Fi+

Amazing volcano view villa
Vacation home rentals with a washer and dryer

Apartment in 9 Norte with parking

Cozy apartment in Playa Gorgona

Brand new apt. w/rooftop pool & jacuzzi. Palermo

Morros Epic - Sea view, near to Holiday & Radisson

Beautiful and perfect Studio 300 mb wifi and Location

Port Vell, 4 BR/4 BA, pool, bar and now with A/C

Jungle Oasis: Sea&City Views with Ruby Sunsets

Cavancha Peninsula Beach View + Parking
Destinations to explore
- Hostel rentals South America
- Campsite rentals South America
- Cave rentals South America
- Ski-in/ski-out rentals South America
- Cottage rentals South America
- Rentals with breakfast South America
- Rentals with a home theater South America
- Family-friendly rentals South America
- Yurt rentals South America
- Rentals with pools South America
- Bungalow rentals South America
- Smoking-friendly rentals South America
- Rentals with an EV charger South America
- Rentals with beach access South America
- Tent rentals South America
- Apartment rentals South America
- Villa rentals South America
- Rentals with an accessible height bed South America
- Cabin rentals South America
- Dome rentals South America
- Serviced apartment rentals South America
- Chalet rentals South America
- Rentals with a patio South America
- Rentals with outdoor seating South America
- Luxury rentals South America
- Rentals with lake access South America
- RV rentals South America
- Houseboat rentals South America
- Rentals with a kayak South America
- Tipi rentals South America
- Barn rentals South America
- Bed and breakfasts South America
- Shipping container rentals South America
- Private suite rentals South America
- Rentals with a sauna South America
- Waterfront rentals South America
- Boat rentals South America
- Pet-friendly rentals South America
- Boutique hotel rentals South America
- Condo rentals South America
- House rentals South America
- Loft rentals South America
- Guesthouse rentals South America
- Rentals with a hot tub South America
- Hotel rentals South America
- Nature eco lodge rentals South America
- Entire floor rentals South America
- Treehouse rentals South America
- Farmstay rentals South America
- Townhouse rentals South America
- Aparthotel rentals South America
- Tiny house rentals South America
- Rentals with a balcony South America
- Resort rentals South America
- Island rentals South America
- Rentals with a firepit South America
- Rentals with an accessible height toilet South America
- Fitness-friendly rentals South America
- Ranch rentals South America
- Beachfront rentals South America
- Rentals with a washer and dryer South America
- Earth house rentals South America
- Rentals with a fireplace South America