Hotel vacation rentals in Southern Oregon

Find and book unique hotels on Airbnb

Top-rated hotels in Southern Oregon

Guests agree: these hotels are highly rated for location, cleanliness, and more.

0 of 0 items showing

1 of 3 pages

Top guest favourite

Hotel room in Ashland

4.89 out of 5 average rating, 9 reviews

Swank Suites/ Boutique Travel

Swank Boutique Suites | King Suite with Soaking Tub | Downtown Ashland Experience detailed hospitality and plush amenities while exploring Ashland. STEPS TO ALL ASHLAND HAS TO OFFER. STAY AND PLAY AT SWANK HOUSE SUITES. 🔹 1 block to grocery store 🔹 2 blocks to Ashland Escape Room 🔹 3 blocks to start exploring all the downtown restaurants 🔹 4 blocks to Growler Guys 🔹 6 blocks to Ashland's Plaza Center 🔹 7 minute walk to Chozu Bath & Tea Gardens 🔹 BIKE & HIKE (ride from your front door

Superhost

Hotel room in Eugene

4.81 out of 5 average rating, 37 reviews

Market District, walk to Autzen, Downtown, River!

Stylish, newly renovated boutique motel in the heart of Eugene! Steps from great food, nightlife, and shopping, and just minutes from the University of Oregon and Hayward Field. Enjoy free parking, WiFi, HD streaming, mini fridge, microwave, coffee station, and upscale bath amenities. Keyless, contactless check-in/out for convenience. Easy access to downtown and the freeway. Designed and operated by a local, offering charm & comfort in every detail. Stay close to everything Eugene has to offer!

Guest favourite

Hotel room in Bandon

4.9 out of 5 average rating, 125 reviews

Seaside Suite | Full Kitchen + Living Room

Originally designed as our innkeeper's suite, this apartment is truly made to be your home away from home! Nestled on the coast of Bandon, our inn offers the perfect blend of contemporary amenities and seaside enchantment. With its prime location just steps from the marina and minutes from world-renowned golf courses, Bandon Marina Inn is the ultimate destination for those seeking excitement and relaxation. Come discover your slice of paradise and make us your home away from home in Bandon.

Superhost

Hotel room in Eugene

4.91 out of 5 average rating, 74 reviews

Chic + Luxe ApartHotel in the pulse of the city

Effortless style and muted pastel accents offer sophistication and simplicity. Completely restored 1910 apartment building. Comfortable loft style space with every detail considered. Perfect kitchen for cooking a full meal. Smart 65" TV in the living/sleeping area ready for streaming. West Elm sofabed with Brooklinen luxury linens and towels. Public Goods bath essentials. Dining table for 2 and also a dedicated desk workspace with hi-speed wi-fi throughout. AC/Heat with a digital thermostat.

Guest favourite

Hotel room in Gold Beach

4.96 out of 5 average rating, 120 reviews

Coastal King Room at Endicott Gardens 21 & Over

Welcome to Endicott Gardens Bed & Breakfast, Spa and Tea House! We are a smoke free, pet free, 21 and over venue where you can get away from it all and relax! You can also add on our organic, innovative farm to table breakfast to your stay (breakfast is additional). All rooms have private ensuite bathrooms and your own heat and air! This room features a King Bed, with private bath and tub/shower combo! We are located 7 minutes from the ocean and right across the street from the river!

Superhost

Hotel room in Redmond

4.78 out of 5 average rating, 23 reviews

Bell Air Motel | Cottagecore Room

Perfectly located & appropriately priced. Our Cottagecore Rm is perfect for explorers seeking beauty & adventure in Central Oregon. Our 1940s roadside motel is undergoing a facelift. The Cottagecore Rm is our 2nd available to vacationers in decades. This room has a RELAXINGVIBE. 10 miles south to Bend, 10 min. north to Redmond, 15 min. to Smith Rock, 20 min. to Sisters, a western town, 45 min. to Mt Bachelor world-class 6th largest ski resort in North America- KOWABUNGA!!!

Superhost

Hotel room in Ashland

4.8 out of 5 average rating, 5 reviews

The Peerless Hotel| Signature Room 6| Clawfoot Tub

Located on the second floor, our most petite yet whimsical guest room features exposed brickwork, a clawfoot tub for soaking, and one of the original cast iron beds from the hotel dating back to the 1920s. Its period inspired décor and floral details welcome you home as one of the best examples of “vintage coziness” our historic hotel has to offer. Every Peerless room is walking distance from all the restaurants, seasonal activities, and OSF performances Ashland has to offer!

Guest favourite

Hotel room in Medford

4.86 out of 5 average rating, 44 reviews

City Center Motel - Queen Room

City Center Motel, your go-to for modern comfort and convenience. Family-owned with a personal touch, our rooms are designed to make your stay easy and relaxing. Enjoy amenities like air conditioning, a refrigerator, microwave, K-cup coffee maker, hair dryer, iron and board, and free Wi-Fi. Whether you’re here for work or leisure, our dedicated team is committed to providing excellent service and ensuring a memorable stay. Experience comfort and care, all in one place.

Superhost

Hotel room in Yachats

4.75 out of 5 average rating, 712 reviews

Pedal Out - Blue

This hostel-style space is located within an eclectic complex of boutique lodging at The Drift Inn, Yachats, Oregon. This tiny room offers a step up from "bare essentials." It includes a flat-screen TV, storage for luggage under the bed, and a small fold-down table with chair for seating. The bed dominates the majority of the room, so be aware when booking - this is a very tiny private bedroom. (Shared restrooms, showers, and kitchenette are across the hall.)

Superhost

Hotel room in Sisters

4.67 out of 5 average rating, 6 reviews

King Suite|Kitchenette| HOT TUB|Dog Friendly

Enjoy our newly remodeled, 11 unit, boutique lodge in downtown Sisters! Come stay in one of our 2 room King Suite's featuring a kitchenette, bathroom and king bed. Second adjoining room adds additional living space to safely store bikes, skis, and other gear. Also has a couch, TV, table, and desk that can serve as a work from home or additional living room space. Monthly rental available. There is a $35 fee and a $20 fee for an additional pet

Guest favourite

Hotel room in Sisters

4.96 out of 5 average rating, 133 reviews

Ski Inn Taphouse Hotel, Downtown Sisters- Room 104

Enjoy our brand-new, 6 unit, boutique hotel located in the heart of downtown Sisters, Oregon. This listing is for Room 104 featuring a king bed, seating area, private bathroom, and access to the shared, wrap-around patio with breathtaking views of the Three Sisters mountain peaks. You'll experience a private, unique setting upstairs while having the option to eat and drink as a local downstairs at the Ski Inn Taphouse.

Superhost

Hotel room in Bandon

4.82 out of 5 average rating, 101 reviews

B. Iconic: Feel the POWER in this 2-bed room

Welcome to the B-Side Motel & RV Park located in gorgeous Bandon on the famous Oregon Coast! Come enjoy year-round fishing, hiking, beach-combing, golf or simply relaxation in one of Oregon’s most beautiful gems. Your private room includes two queen beds with plush linens, private bathroom with shower and access to on-site facilities such as free wi-fi, clean bathrooms, shared outdoor spaces, and a coin-op laundry.