
Vacation rentals in Chepo
Find and book unique accommodations on Airbnb
Top-rated vacation rentals in Chepo
Guests agree: these stays are highly rated for location, cleanliness, and more.

Apto 4 min from Tocumen Airport | 24-hr check-in
Layover in Panama? Stay where everything is easy and comfortable Just 4 minutes from Tocumen International Airport – perfect for early flights or quick stopovers A modern, comfortable, and secure apartment with: • Fast WiFi and air conditioning • Smart lock and flexible check-in • 24/7 security • Pool, gym, and fully equipped kitchen • Steps from the ITSE Metro station Ideal for layover travelers, curious tourists, or business trips. 🌴 Just arrive — everything’s ready for you. We’ll be waiting!

Mountain Retreat
Relax and unwind at this peaceful property nestled on two hectares of lush tropical vegetation surrounded by the sights & sounds of nature. Located at Panama's Blue Mountain(Cerro Azul), 30 kilometres from Panama City. This cozy & comfortable home is equipped with modern amenities & chic decorative touches. It consists of a main house with 2 bedrooms & a 2 bedroom cottage. It has a spacious terrace, pool & jacuzzi overlooking Panama City. The property also boasts its own spring water well

The Crystal House: Luxury Modern Wood Cabin
Crea recuerdos inolvidables en este alojamiento único e ideal para familias. Quédate en una cabaña en medio del Parque Nacional Chagres a 50 minutos de la ciudad. Podrás estar en contacto con la naturaleza contando con todas las comodidades de un alojamiento de lujo. Con una de las mejores vistas a la ciudad puedes disfrutar de una buena barbacoa, una siesta en la hamaca o una reunión alrededor de la chimenea. Relájate y conéctate con el lindo verde de Panamá. Te esperamos!

Entire Villa with pool in front of beach!
Beautiful spacious 4 bedroom villa right in front of the sea. Enjoy the swimming pool with your family, then take a dip into the sea only steps away. Very pet friendly! Take a boat trip for the day with a local certified tour guide from portobelo town. Every room has full AC, including the living room - but please be conscious of the environment when using ACs. Excellent WiFi ! Open Kitchen, with breakfast included. We can also arrange for lunch - fresh lobster!

Patty’s Casco 2BR Loft | Balcony & Personal Touch
“Feel at home in Casco Viejo—personally welcomed by your hosts, Patty & Rudy.” Stay in the Heart of Casco Viejo with Patty’s Casitas! Prime Casco Viejo Location | Quiet, Convenient & Charming Stay steps from restaurants, cafés, bars, and plazas—right by the El Rey boutique supermarket and the waterfront promenade. This peaceful spot is rare in Casco, tucked away from rooftop noise and perfectly located at the entrance of the neighborhood for easy in & out access!

Cabin near the city, luxurious treehouse
Without leaving the city, live a unique experience, stay in a real tree house, inside you will find a double bed for 2 people, sofa bed ideal for a child, full bathroom, kitchen, breakfast, balcony, WiFi TV, inflatable jacuzzi and hammocks, the garden has a camping area with bathrooms if you want to camp with friends *extra price per person. Boat tour to the waterfall* extra price. Gazebo with outdoor kitchen, gas grill, to enjoy outdoor meals and campfire area.

Casa Rosie - Dream Home on Tabogá Island
Casa Rosie is a gorgeous villa on Taboga island with an intimate vibe and spectacular views of the ocean. The perfect place for couples, small groups, and families to unwind and make magical memories! . With great wifi, fully equipped kitchen, 3 inviting bedrooms, and a spacious yet personal feel… Casa Rosie is your home away from home. Included in every stay is free pick up and drop off to the ferry terminal - please let us know the details of your arrival.

Airport 7 km away | 24-hour check-in
✈️ Perfect for layovers, late or early flights and short stays Stay just 10 minutes from Tocumen Airport and recharge comfortably before your next flight. • Easy Check-in 🛏️ Private studio for up to 2 guests ❄️ Air conditioning 📶 Fast WiFi 🚿 Hot shower 🍳 Equipped kitchen 🔒 Safe residential community 🚗 Airport shuttle available (pre-book) 🕒 Flexible self check-in after 3pm Ideal for travelers in transit, couples, or short stays without hassle.

Loft 3b Old Town Best! It's 150 m2 (492 feet)
Immerse yourself in the historic charm and modern elegance of our 3-bedroom, 150 m2 loft in the heart of the Old Town. With wooden floors that radiate warmth and a modern open-plan kitchen ideal for sharing, this space guarantees a memorable vacation. Located on Avenida A, you'll find yourself just a few steps away from exquisite restaurants, museums, colonial churches, and the Casco's coveted rooftops, making every day an adventure.

Altos de Cerro Azul | AC, Full Kitchen, 2 Rooms
Some escapes stay with you. This is one of them. Located in the highlands of Altos de Cerro Azul, this modern mountain home is perfect for disconnecting without giving up comfort. Wake up to panoramic views, breathe cooler air, and enjoy true peace. Ideal for couples, small families, or remote workers seeking a calm retreat in nature. Traveling as a couple? Ask us about a special rate. No pets allowed.

Private Studio 10 Min from the Airport!
Apartamento Entero 10 MINUTES FROM the Airport! The apartment is fully furnished, including appliances and kitchen items, cleaning products, a living/dining room, a work table, and more. Just a few minutes' walk from the SAN ANTONIO and METROMALL METRO stations. We offer tours to San Blas -Tours to Monkey Island and the Panama Canal to make the most of your trip. Our home is Your home in Panama 🇵🇦

Luxury Centric 2BR Apartment in Casco Viejo
Welcome to our charming and spacious apartment in the heart of Casco Viejo. We are located directly across the street from the landmark Hotel La Compañia. From the balcony you can look at the remaining structure of the centuries-old La Compañia de Jesus, a former Jesuit temple and convent. In the apartment, you can relax in the spacious and comfortable space.
Popular amenities for Chepo vacation rentals
Other great vacation rentals in Chepo

Most Beautiful Loft in the Heart of Casco Viejo

Villa la Vista - majestic mountain hideaway

Blue Pine House, Natural Escape + Jacuzzi + Relax

Casa Condal - Your Private Nature Eco-Retreat

Cozy Apartment in the Heart of Casco Viejo

Gorgeous Flat in the best location in Casco Viejo

Carmen's House

Hyde hill Luxury Cabin with amazing views
Destinations to explore
- Panama City Vacation rentals
- San Andrés Vacation rentals
- Puerto Viejo de Talamanca Vacation rentals
- Boquete Vacation rentals
- Playa Blanca Vacation rentals
- Valle de Antón Vacation rentals
- Coveñas Vacation rentals
- Ancón Vacation rentals
- Limon Vacation rentals
- David Vacation rentals
- Playa Venao Vacation rentals
- Cahuita Vacation rentals





