
Hotel vacation rentals in Central Business District
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Top-rated hotels in Central Business District
Guests agree: these hotels are highly rated for location, cleanliness, and more.
Vacation rentals for every style
Get the amount of space that is right for you.
Popular amenities for Central Business District hotels
Family-friendly hotels

First Floor One Bedroom King Suite

Second Floor King Standard

Galt House | Exec Suite 2 Queens | Walk to Museums

First Floor Queen Standard

Petite King Standard

Hawthorn Louisville | 1 King Suite | Pet-Friendly

Queen Suite (ADA) at The Bellwether Hotel

King Standard First Floor
Hotels with a pool

Experience True Southern Comfort | Free Breakfast

The Perch at The Purple Martin in Louisville!

The Nook at The Purple Martin in Louisville!

The Plume at The Purple Martin in Louisville

The Odd Bird at The Purple Martin in Louisville

Spacious Stay | Pool | Muhammad Ali Center–0.35mi

The Stop Over at The Purple Martin in Louisville

Southern Comfort In Downtown Louisville
Hotels with a patio

Modern stay-near Fort Knox

Welcome to the Bourbon Lifestyle

Elegant & New I-65 Sophisticated Model Home

Unique and Cozy Front Upper Unit

Stay at the Mod Pod!
Destinations to explore
- House rentals Downtown
- Rentals with a firepit Downtown
- Rentals with a patio Downtown
- Waterfront rentals Downtown
- Rentals with outdoor seating Downtown
- Pet-friendly rentals Downtown
- Loft rentals Downtown
- Condo rentals Downtown
- Fitness-friendly rentals Downtown
- Rentals with a washer and dryer Downtown
- Rentals with breakfast Downtown
- Rentals with an EV charger Downtown
- Rentals with pools Downtown
- Family-friendly rentals Downtown
- Rentals with an accessible height toilet Downtown
- Apartment rentals Downtown
- Rentals with a hot tub Downtown
- Hotel rentals Louisville
- Hotel rentals Kentucky
- Hotel rentals United States
- Buffalo Trace Distillery
- Kentucky Kingdom & Hurricane Bay
- Kentucky Derby Museum
- Valhalla Golf Club
- Angel's Envy Distillery
- Muhammad Ali Center
- Louisville Slugger Field
- Louisville Slugger Museum & Factory
- Heritage Hill Golf Club
- Turtle Run Winery
- Charlestown State Park
- Waterfront Park
- Big Four Bridge
- Kentucky Science Center
- Falls of the Ohio State Park
- River Run Family Water Park
- Frazier History Museum
- Evan Williams Bourbon Experience
- Big Spring Country Club
- Rising Sons Home Farm Winery
- Bruners Farm and Winery
- McIntyre's Winery
- Lovers Leap Vineyards and Winer
- Best Vineyards