
House vacation rentals in Central Business District
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Top-rated house rentals in Central Business District
Guests agree: these houses are highly rated for location, cleanliness, and more.

NuLu & Angel’s Envy at Your Door| Great for Groups
This spacious, personality-filled home in the heart of downtown is the perfect base for bourbon trail weekends, weekday corporate stays,or family get-togethers. You can walk everywhere! With 3,000 sq ft of flexible space it's great for group connection; there's a private patio, plenty of gathering zones, comfy beds, a chef’s kitchen, and thoughtful touches that make your stay feel special. The home is soulful and full of character—ideal for groups who value comfort, style, and a great location.

Bourbon Trail Spacious Backyard NEW HotTub Grill!
The Burnt Barrel, discover your vibrant Louisville getaway! Perfect for couples, business travelers, or event visitors, this cozy home offers high-speed Wi-Fi and a dedicated workspace, fully equipped kitchen, and a NEW hot tub and grill for you to enjoy! Guests rave about its comfort, walkable location, and modern amenities. Enjoy nearby bars and restaurants all just minutes from downtown, UofL Health, and the Convention Center. Experience true Louisville charm and convenience! Book a stay now!

2 br home, walking distance to much entertainment
Home located in the historic Irish Hill neighborhood, just a short walk to popular Baxter Ave and Bardstown Rd, famous for its restaurants, coffee shops and nightlife. Downtown and Nulu are a very short drive away, many great bars and distilleries are walking distance. Home built in 1879, entirely renovated with a modern kitchen, fully fenced backyard, private parking and fire pit.Master bedroom has a king size bed and it’s own bathroom with jetted tub. We look forward to your visit, thank you!

Private Parking in GTownWalk to Coffee,Shops,Bars!
Shotgun Rye is ready to host your stay in Louisville! Located close to everything cool in Germantown and Highlands area! People visit for Bourbon Tours, Ky Derby, Conventions, Expo Ctr, UL graduations and sporting events, live music and so much more! Completely remodeled with all the modern conveniences & a comfortable, casual touch. But with so much to see and do in Louisville you’ll load up your itinerary with unforgettable experiences. Great location walk to bars, restaurants and shopping!

Butchertown & NuLu's Shantyboathouse
Welcome to the Shantyboathouse! Recognized as a truly unique property, it has twice been featured in the Courier-Journal and was honored with a historical plaque by the Louisville Landmarks Commission in 2019. According to a 1976 newspaper article, a local legend recounts that the house floated up the river during the 1937 flood, and was later set on a foundation—earning it the enduring nickname, "the shanty boat." This rich history adds to the property's distinctive character and charm.

Quiet Neighborhood Home With Outstanding Location
Situated on a quiet hilltop neighborhood in Clifton Heights, this is the perfect location for a professional or personal visit to Louisville and very animal friendly. It is within 10 minutes of Downtown, Waterfront Park, Nulu, Frankfort Avenue, the Highlands, the Convention Center, and just 15 minutes from historic Churchill Downs. These neighborhoods feature the best dining and entertainment in the city. Just a block away is the Mellwood Arts Center complex with shops and dining.

The House with the Orange Door
Located near Churchill Downs, UofL, downtown, the Convention Center and Fairgrounds, and a short distance to restaurants, bars and coffee shops. This single family home offers two bedrooms with queen beds and a pull-out couch in the living room. Enjoy coffee or a relaxing evening cocktail on the back deck. The kitchen is fully equipped and the open living space provides a great area for socializing. Locally made art and decor is on display, adding to the uniqueness of the space.

Limerick Carriage Company - Happy Holidays!
The Carriage House is ready for Christmas! Our Carriage House is warm and inviting to guests from all over. We are located close to downtown, Central Park, UofL, & the Bardstown Road corridor. There are many unique shops, restaurants, bars, & places to visit close by, and some are walkable in warmer weather. The Carriage House has undergone a complete renovation - we hope you love it as much as we do! Don’t let the outside fool you - the inside of our home is the treasure!

Best Location in the City-2 Story Patio & Hot Tub
The Saddle Inn has everything you need for your upcoming stay. Situated in the heart of the city and walking distance to the best restaurants and bars in town, you are booking convenience when you book our home. This house has vintage Kentucky flare with modern furnishings & updates. It boasts 3 bedrooms, a 2 story patio, hot tub, fire pit, ping-pong table, shuffleboard, and all the bourbon barrels one can hope for in Kentucky. There's no better location than this one.

Stay in Historic Butchertown, Blocks From NuLu
With its prime location at 1025 E Main St at the intersection of Louisville's Butchertown and NuLu neighborhoods, you'll be blocks away from the city's most vibrant and exciting districts. With this beautifully renovated, designer-curated home as your base, walk to the area's trendiest shops and restaurants, sample local craft beers at one of the nearby breweries, or enjoy tastings on one of the many bourbon tours that the city is famous for.

The Caldwell Highlands/Germantown
Welcome to The Caldwell, a Germantown/Highland area home that includes three bedrooms, one and half bathrooms and sleeps up to five people. The home is within walking distance of several restaurants, bars, retail and vintage stores, and entertainment venues including the Germantown Gables, Logan Street Market and Old Forester’s Paristown Hall. The home features a covered deck, a fenced-in yard as well as home gym.

Historic Parsonage in heart of NuLu action
Located in a lovingly renovated 1843 church, this small apartment boasts a queen-size bed, full bathroom, kitchenette with table for 3, and comfy sofa. You'll be in the middle of all Market Street has to offer — steps from Rabbit Hole Distillery, Nouvelle Wine Bar, Garage Bar, and tons more. A 10-minute ride from the airport, you'll be half a mile from Slugger Field, and 1 mile from the YUM! and Convention Centers.
Popular amenities for Central Business District house rentals
House rentals with a pool

The Getaway!

The Ville Getaway! Centrally Located

5 Baths• King Beds• Hot Tub • Expo & Bourbon Trail

Germantown Gem - 3BR/2BA Home with Stock Tank Pool

Peppermint Cottage Norton Commons w Breakfast

CIRCO LOCO - uNCommon Stay

Close to everything / Huge

Downtown->Heated Pool, Firepit, Bikes, Grill, Pets
Weekly house rentals

Lil Blue-Cheerful, fully renovated & updated home

Modern stay for Derby minutes from Churchill Downs

Charming Shotgun Style Home, Great Location

Highlands Lookout-3BR 3.5BA-Walk to Tons +Parking

Private 2BR Carriage Home/kitchen/laundry sleeps 4

Germantown gem w/ private parking & fenced in yard

Charming Highlands Home | Walk to Everything

Walkable, 5 King beds, Firepit, Bourbon Trail, BBQ
Private house rentals

Colonel Lou Lou's

~Modern~Luxury 3BR~Walkable~Central AC~

Bourbon Lounge in NULU>Hot Tub>King Beds>Fire Pit!

Lay Low B-Side | NULU | 2BR | Balcony

The NULU Hideaway - downtown Louisville

Peaceful Modern Retreat • Prime Location!

Magical Fairytale Nulu - Historic 2BR Pet Friendly

Louisville Luxury: Expo Center, Large Kitchen
Quick stats about house rentals in Central Business District

Nightly prices starting at
Central Business District vacation rentals start at $291 CAD per night before taxes and fees

Verified guest reviews
Over 240 verified reviews to help you choose

Popular amenities for guests
Guests love Kitchen, Wifi, and Pool across Central Business District rentals

4.9 Average rating
Central Business District stays are highly rated by guests—averaging 4.9 out of 5!

Nearby attractions
Central Business District’s top spots, include Fourth Street Live!, Louisville Slugger Museum & Factory, and Louisville Slugger Field
Destinations to explore
- Rentals with a firepit Downtown
- Rentals with a patio Downtown
- Waterfront rentals Downtown
- Rentals with an EV charger Downtown
- Hotel rooms Downtown
- Loft rentals Downtown
- Condo rentals Downtown
- Fitness-friendly rentals Downtown
- Rentals with a washer and dryer Downtown
- Apartment rentals Downtown
- Rentals with a hot tub Downtown
- Rentals with an accessible height toilet Downtown
- Rentals with breakfast Downtown
- Family-friendly rentals Downtown
- Rentals with outdoor seating Downtown
- Pet-friendly rentals Downtown
- Rentals with pools Downtown
- House rentals Louisville
- House rentals Jefferson County
- House rentals Kentucky
- House rentals United States
- Buffalo Trace Distillery
- Kentucky Kingdom & Hurricane Bay
- Kentucky Derby Museum
- Valhalla Golf Club
- Angel's Envy Distillery
- Muhammad Ali Center
- Charlestown State Park
- Heritage Hill Golf Club
- Louisville Slugger Museum & Factory
- Louisville Slugger Field
- Big Four Bridge
- Turtle Run Winery
- Kentucky Science Center
- Falls of the Ohio State Park
- Waterfront Park
- River Run Family Water Park
- Hurstbourne Country Club
- Frazier History Museum
- Big Spring Country Club
- Evan Williams Bourbon Experience
- Rising Sons Home Farm Winery
- Bruners Farm and Winery
- Best Vineyards
- Lovers Leap Vineyards and Winer




