
Boutique hotels in Gainesville
Find and book unique boutique hotels on Airbnb
Top-rated boutique hotels in Gainesville
Guests agree: these boutique hotels are highly rated for location, cleanliness, and more.

Buddha Room: Walk DNTN | Micro Apt | Pet Friendly
Welcome to Depot Village! A unique boutique hotel experience rich w/ traditional Florida charm near Gainesville's lively downtown! Perfect for a cozy luxury base while exploring North-Central Florida. Enjoy downtown living blocks from fantastic dining, cafes, bars, nightclubs, & breweries. Ideal for getaways, business trips, local events, music festivals, springs visits, hiking, biking, & Gator games. Minutes from UF, Shands Hospital, Depot Park, Hawthorne Trail, Heartwood, GNV airport & more!

Green Room: Walk DNTN | Lux Apt | Pet Friendly
Welcome to Depot Village! A unique boutique hotel experience rich w/ traditional Florida charm near Gainesville's lively downtown! Perfect for a cozy luxury base while exploring North-Central Florida. Enjoy downtown living blocks from fantastic dining, cafes, bars, nightclubs, & breweries. Ideal for getaways, business trips, local events, music festivals, springs visits, hiking, biking, & Gator games. Minutes from UF, Shands Hospital, Depot Park, Hawthorne Trail, Heartwood, GNV airport & more!

Treehouse Suite: Walk DNTN | Apt | Pet Friendly
Welcome to Depot Village! A unique boutique hotel experience rich w/ traditional Florida charm near Gainesville's lively downtown! Perfect for a cozy luxury base while exploring North-Central Florida. Enjoy downtown living blocks from fantastic dining, cafes, bars, nightclubs, & breweries. Ideal for getaways, business trips, local events, music festivals, springs visits, hiking, biking, & Gator games. Minutes from UF, Shands Hospital, Depot Park, Hawthorne Trail, Heartwood, GNV airport & more!

Azalea Room at Magnolia Plantation
All rooms inside the main house have TV's, private baths, coffee makers. No children, pets or smoking allowed inside main house. Walking distance to many fine restaurants downtown and Depot Park in a quiet, safe neighborhood. This historic house was restored in 1991 and the owners live onsite. Breakfast is not a part of your stay. We are license and inspected. The owners live onsite to assure your stay is enjoyable.

Magnolia Room at Magnolia Plantation
The Baird Mansion was built in 1885 and has been decorated with period pieces while being updated with modern comforts. The Magnolia Room is the home's master bedroom and is still the home's largest. It has an entrance foyer and a private bath. It is surrounded by windows and has a fireplace. Breakfast is not a part of your stay. We are licensed, inspected and in complete compliance with all life safety codes.

Gardenia Room at Magnolia Plantation
The Gardenia Room invites you to sit & read a book in the bay windows, overlooking the tranquil gardens below. Step outside the 1885 mansion to roam the gardens or to the easily accessible downtown area & Depot Park. Breakfast is not a part of your stay. This property is inspected and licensed, in full compliance with all life safety codes. The owners live on property to be of your assistance.

Aurora's Room - Sweetwater Branch Inn
Aurora Room is located on the second floor of the historic McKenzie House. With its Asian-inspired decor and king-size bed, it is an unbeatable room. Note: this room is street side. May not be a good fit for light sleepers. This room is also able to connect to Giovanna Room if your friends or family want to tag along! Note: this room is street side and may not be suitable for light sleepers.

King ADA Guestroom w/ Roll-in Shower | Near UF
Designed for accessibility and relaxation, this King Guestroom at Hotel Eleo features a spacious layout, roll-in shower, and modern ADA-compliant amenities. Enjoy a plush king bed, mini fridge, Nespresso coffee maker, and TV. Located on the University of Florida campus near UF Health hospitals, this room provides comfort, convenience, and inclusive design for all travelers.

City View Guestroom near UF Campus | Sleeps 4
Experience comfort and modern design in this City View Two Queen Guestroom at Hotel Eleo. With two plush queen beds, TV, mini fridge, and an in-room Nespresso coffee maker, this room is ideal for families, friends, or campus visitors. Enjoy city views and thoughtful amenities while staying just steps from UF Health hospitals and the University of Florida campus.

Tiffany Suite - Sweetwater Branch Inn
Our Tiffany Suite located on the second floor of the Cushman-Colson house really has it all. Located near the balcony and reading nook, it has recently been updated to include a brand-new pull out couch. This room is classy and we have the clawfoot tub and chandelier to prove it. Note: this room is street side and may not be suitable for light sleepers.

Jasmine Room at Magnolia Plantation
Jasmine is the 1st floor room in our inn. This room was the original library & still shows that 1885 charm. There is an antique queen bed with love seat and TV/DVD player. The room has a private bath with an antique clawfoot tub. Breakfast is not a part of your stay. We are licensed & inspected. The owner lives on property for your assistance.

Lake View Two Queen Guestroom near UF Campus
Perfect for families or friends, the Lake View Two Queen Guestroom at Hotel Eleo offers modern comfort with scenic lake views. This room features two plush queen beds, a mini fridge, a Nespresso coffee maker, and TVs. Located on the University of Florida campus, it’s ideal for campus visits, medical stays, or weekend getaways in Gainesville.
Popular amenities for Gainesville boutique hotels
Family-friendly boutique hotels

Buddha Room: Walk DNTN | Micro Apt | Pet Friendly

Magnolia Room at Magnolia Plantation

Luisa's Room - Sweetwater Branch Inn

Green Room: Walk DNTN | Lux Apt | Pet Friendly

Jasmine Room at Magnolia Plantation

Tea Rose Room - Sweetwater Branch Inn

Aurora's Room - Sweetwater Branch Inn

Azalea Room at Magnolia Plantation
Other boutique hotel vacation rentals

Buddha Room: Walk DNTN | Micro Apt | Pet Friendly

Magnolia Room at Magnolia Plantation

Luisa's Room - Sweetwater Branch Inn

Green Room: Walk DNTN | Lux Apt | Pet Friendly

Jasmine Room at Magnolia Plantation

Tea Rose Room - Sweetwater Branch Inn

Aurora's Room - Sweetwater Branch Inn

Heather Room at Magnolia Plantation
Quick stats about boutique hotels in Gainesville

Total vacation rentals
Explore 20 vacation rentals in Gainesville

Nightly prices starting at
Gainesville vacation rentals start at $221 CAD per night before taxes and fees

Verified guest reviews
Over 570 verified reviews to help you choose

Vacation rentals with a pool
10 properties feature pools

Wifi availability
20 of Gainesville vacation rentals include wifi access

Popular amenities for guests
Guests love Kitchen, Wifi, and Pool across Gainesville rentals

4.8 Average rating
Gainesville stays are highly rated by guests—averaging 4.8 out of 5!

Nearby attractions
Gainesville’s top spots, include Depot Park, Florida Museum of Natural History, and Royal Park Stadium 16
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