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Hotel vacation rentals in Panama

Find and book unique hotels on Airbnb

Top-rated hotels in Panama

Guests agree: these hotels are highly rated for location, cleanliness, and more.

Superhost
Boutique hotel in Bajo Boquete
Villa Alejandro - Tastefully Furnished Room
Just 5 minutes walk to centre, calmly situated and close to town located in an extraordinary mansion. Lovely furnished bedroom (King-Size/Orthopedic mattress) with private bathroom and walk-in closet . Affectionately decorated living room with spectacular view to the Boquete valley by large windows and large, full equipped kitchen can be shared with other guests. Lot of space for dining/reading in the living room. Lovely garden and terrace can be used. Gated carport. Fast WiFi, CableTV, Netflix
Jun. 20 – 27
$126 CAD per night
4.91 out of 5 average rating, 105 reviews
Superhost
Boutique hotel in PA
Villa Coco King Room
Villa Coco is a beautiful boutique hotel in Santa Catalina, only footsteps away of the world known surf break “La Punta” and Unesco world heritage Coiba island. The carefully designed cabañas, provide a space of tranquility and a sense of timelessness. Unwind in the hammocks and canvas chairs on your private terrace, dwell on reading your favorite book or sip on a cool drink from the bar. Our Restaurant “Ai Mamita” offers different kinds of meat, fresh seafood and other tasty delights.
Jul. 10 – 17
$234 CAD per night
4.89 out of 5 average rating, 28 reviews
Guest favourite
Casa particular in Lagartero
Private Villa with private pool, in Santa Catalina
A beautiful stand-alone 60 sq mt villa, 1 King bed and 1 queen. King size bed in the master bedroom with black out drapes, Queen size bed and fold out couch in the loft area. Full kitchen, living and dining area, flat screen TV, Bathroom with soaps/shampoos, and rainfall showerhead. Large terrace with views as far as the eye can see, with BBQ, dining table and outdoor sectional sofa. Private swimming pool with seating area, pool lounge chairs, lighted gazebo and sun umbrellas.
Oct. 13 – 20
$143 CAD per night
5.0 out of 5 average rating, 8 reviews

Family-friendly hotels

Guest favourite
Casa particular in Bocas del Toro
Urania House
May 31 – Jun. 7
$119 CAD per night
4.96 out of 5 average rating, 80 reviews
Guest favourite
Nature lodge in Panamá
Casa Momote Loma Limon
Apr. 25 – May 2
$65 CAD per night
4.99 out of 5 average rating, 88 reviews
Superhost
Nature lodge in Taboga Island
Eco Lodge Garden Room 4, Oceanview Plunge Pool
Jun. 25 – Jul. 2
$107 CAD per night
4.68 out of 5 average rating, 41 reviews
Superhost
Nature lodge in Puerto Lindo
Hostel Wunderbar Palm Room
Jul. 8 – 15
$49 CAD per night
4.53 out of 5 average rating, 64 reviews
Aparthotel in Alto Boquete
Cabañas Villa San Miguel #1/noquete
Jul. 3 – 10
$107 CAD per night
4.67 out of 5 average rating, 21 reviews
Nature lodge in Isla Bastimentos
Beach Bungalow on Bastimentos w/ Meals & Transport
Dec. 19 – 26
$264 CAD per night
4.92 out of 5 average rating, 24 reviews
Boutique hotel in San Carlos
B) Beach, surf and Relax with King size bed
Jun. 5 – 12
$94 CAD per night
4.83 out of 5 average rating, 84 reviews
Nature lodge in Santa Catalina
Beachfront - Private double bedroom
Jun. 15 – 22
$81 CAD per night
4.8 out of 5 average rating, 15 reviews
Boutique hotel in Playa Morillo, Mariato
Double room IXORA with partial ocean view balcony
Oct. 27 – Nov. 3
$157 CAD per night
4.97 out of 5 average rating, 33 reviews
Nature lodge in PA
VillaHermosa B&B
Mar. 4 – 11
$266 CAD per night
5.0 out of 5 average rating, 5 reviews
Guest favourite
Boutique hotel in Copecito
B&B Cabanas los hummingbirds
Jan. 27 – Feb. 3
$132 CAD per night
4.79 out of 5 average rating, 29 reviews
Guest favourite
Boutique hotel in Punta Chame
Pink Palace Panama
Aug. 2 – 9
$144 CAD per night
5.0 out of 5 average rating, 7 reviews

Hotels with a pool

Guest favourite
Boutique hotel in Lagartero
Charming 1-Bedroom Beachfront Hotel With Pool
Aug. 27 – Sep. 3
$130 CAD per night
5.0 out of 5 average rating, 8 reviews
Guest favourite
Hotel in La Enea
Private apartment with pool/beach access!
Aug. 24 – 31
$73 CAD per night
5.0 out of 5 average rating, 6 reviews
Guest favourite
Hotel room in Colón Island
Deluxe Oceanfront Bungalow - Bird Island Bungalow
Aug. 16 – 23
$223 CAD per night
5.0 out of 5 average rating, 19 reviews
Guest favourite
Boutique hotel in Las Tablas Abajo
Blue Room for 2 - right on the beach!
Jul. 27 – Aug. 3
$82 CAD per night
4.81 out of 5 average rating, 58 reviews
Guest favourite
Room in Panamá
Relax Room
Aug. 12 – 19
$41 CAD per night
4.81 out of 5 average rating, 16 reviews
Superhost
Boutique hotel in Panamá
Pool side, Family suite, two bedroom one bath.
Aug. 30 – Sep. 6
$105 CAD per night
4.88 out of 5 average rating, 17 reviews
Superhost
Hotel in Playa Coronado
Your spot away from home
Feb. 4 – 11
$174 CAD per night
4.83 out of 5 average rating, 18 reviews
Superhost
Hotel in Panama City
Grand International Hotel
Sep. 15 – 22
$62 CAD per night
4.4 out of 5 average rating, 5 reviews
Guest favourite
Hotel in Las Lajas
Beach Apartament Villa Deluxe
Jul. 17 – 24
$113 CAD per night
5.0 out of 5 average rating, 6 reviews
Guest favourite
Nature lodge in Cacique
Isa’s jungle house, Roos
Jan. 29 – Feb. 5
$131 CAD per night
5.0 out of 5 average rating, 5 reviews
Nature lodge in Pueblo Nuevo
Welcome to the heart of the Panama Canal
Mar. 21 – 28
$139 CAD per night
4.86 out of 5 average rating, 7 reviews
Hotel in Bastimentos Island
Selina Red Frog - Teepee Tent
Oct. 2 – 9
$147 CAD per night
4.88 out of 5 average rating, 8 reviews

Hotels with a patio

Superhost
Casa particular in Penonomé
Cozy 1 br 1 bath apartment with free parking
Mar. 15 – 22
$80 CAD per night
5.0 out of 5 average rating, 4 reviews
Casa particular in Río Hato
Villa in Playa Blanca Resort
Mar. 11 – 18
$340 CAD per night
4.5 out of 5 average rating, 4 reviews
Casa particular in Las Lajas
Rent a house in Coronado - Mi Familia
May 2 – 9
$1,174 CAD per night
New place to stay
Superhost
Hotel in Bajo Boquete
Hobbit Home @ Bambuda Castle
Dec. 6 – 13
$217 CAD per night
4.64 out of 5 average rating, 11 reviews
Guest favourite
Room in San Miguelito
Travel break
Sep. 26 – Oct. 3
$39 CAD per night
5.0 out of 5 average rating, 10 reviews
Guest favourite
Shared room in Panama City
Hostal Panama Experience
Mar. 23 – 30
$16 CAD per night
4.86 out of 5 average rating, 7 reviews
Guest favourite
Room in Soná District
SkyRoom- Private room with shared bathroom
Sep. 25 – Oct. 2
$99 CAD per night
4.83 out of 5 average rating, 6 reviews
Nature lodge in San Blas Islands
Natural rooms for disconnecting
Apr. 16 – 23
$87 CAD per night
5.0 out of 5 average rating, 5 reviews
Hotel in Bocas del Toro
Seahorse A/C Mini Garden Cabin
Apr. 16 – 23
$103 CAD per night
4.59 out of 5 average rating, 39 reviews
Guest favourite
Boutique hotel in El Valle de Antón
Suite medievale natura & arte
Mar. 6 – 13
$133 CAD per night
4.38 out of 5 average rating, 8 reviews
Resort in Boca Chica
LIVE WITH MONKEYS ON ISLA BOCA BRAVA (HAB.C.)
Apr. 2 – 9
$50 CAD per night
4.67 out of 5 average rating, 9 reviews
Nature lodge in Bastimentos Island
AC Cabana at Palmar Beach Lodge
Jan. 12 – 19
$333 CAD per night
4.83 out of 5 average rating, 6 reviews

Destinations to explore

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