Hotel vacation rentals in Panama

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Top-rated hotels in Panama

Guests agree: these hotels are highly rated for location, cleanliness, and more.

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Superhost

Hotel room in Panamá

4.83 out of 5 average rating, 6 reviews

Avani Eco Hotel ~ Romantic Nature Getaway ~ Patio!

Step into the comfort of this beautiful queen suite in the high-end, eco-friendly Avani Boutique Hotel, offering easy access to sandy beaches and the many stunning amenities and activities of Contadora Island. Spend the day exploring this breathtaking island and then retreat to the attractive suite whose stylish design and scenic surroundings will mesmerize you. ✔ Comfy Queen Bed ✔ Spa-Like Bathroom ✔ Private Patio ✔ Wi-Fi ✔ Hotel Amenities (Breakfast, Transport, Activities) Learn more below!

Guest favourite

Private room in Río Hato

4.94 out of 5 average rating, 16 reviews

Decameron Villas Private Room #2

The perfect location for beach lovers! Just a 5 minute walk to the private Del Mar Beach Club with beach, pool and restaurant. A quiet community pool is also steps away from the villa. This spacious hotel style room with private bath and small balcony overlooking the Mantarraya Golf Course, has 2 double beds (2 adults and 2 children), dresser, closet, coffee pot, mini-fridge, air conditioning, and ceiling fan. A toaster oven is available for stays longer than 5 days. Golf is available for a fee.

Superhost

Private room in Bastimentos Island

5 out of 5 average rating, 3 reviews

Near Attractions & Beach; King Bed; Breakfast Incl

Unwind and indulge at The Lodge at Punta Rica, your favorite Caribbean eco-lodge retreat, privately nestled in the jungle canopy of Bastimentos Island. Located just up the hill from our dock and private beach, you are only 10 minutes from downtown Bocas Del Toro. You’ll have easy access to stunning beaches, water activities, restaurants, local markets & shops, nightlife, lush nature & more. Book your ULTIMATE ADULT GETAWAY now and experience culinary delight & the adventure of off-grid living!

Superhost

Hotel room in Bajo Boquete

4.71 out of 5 average rating, 14 reviews

The Residence - Family Room

Just a 10 minute walk to downtown Boquete this modern & contemporary furnished room for max 4 people is located on the second floor in an extraordinary tastfully furnished mansion. The beautiful terrace with a natural waterfountain is surrounded by gorgeous green areas inside a birdparadise. Stylish room (2 Queen-Size/Orthopedic mattress) with private bathroom & walkin closet. Huge lobby with different sitting areas. Big shared kitchen, dining area, free parking, fast Wifi, cable TV, Netflix.

Superhost

Private room in Taboga Island

4.91 out of 5 average rating, 58 reviews

Eco Lodge Garden Room 5 Oceanview Plunge Pool

Experience Cerrito Tropical Eco Lodge. Relax. Enjoy our refreshing plunge pool. Natural hillside location, interpretive garden. Jaw dropping oceanview from pool/deck (pool chairs, UV umbrellas). Walk to the beach. Comfortable ground floor room with bathroom, airconditioning, free Wifi and local TV. Exterior oceanview /gardenview balcony. Birdwatchers can spot up to 124 species recorded on Taboga. Artisanal pizza made onsite. Local taxes 10%. No pets in the Garden Rooms.

Superhost

Hotel room in Isla Colon

5 out of 5 average rating, 15 reviews

Hotel Palma Royale - 1 bedroom suite w/ kitchen

Luxury suite with separate bedroom with queen size bed, kitchen, and living area, balcony with spectacular sea views, bathroom with rain water shower, office desk, air conditioning, coffee pot with grinder and panamanian coffee beans, flat screen tv with cable, upper floors, free wifi, large quality windows and doors, pillow top mattresses, marble or coral tile, bamboo flooring, non-smoking rooms, beach towels, umbrellas, blow dryers, laundry service, board games.

Superhost

Hotel room in Las Lajas

4.33 out of 5 average rating, 6 reviews

Beach Palace Retreat

Sumérgete en el verdadero paraíso en nuestro "Beach Palace Retreat". Esta espaciosa casa de 3 habitaciones en Show Pony Beach Resort ofrece una combinación perfecta de lujo y comodidad. Relájate en los elegantes espacios interiores, disfruta de las vistas al océano desde la terraza y goza del acceso directo a la arena dorada. Con comodidades modernas y un ambiente sereno, te espera unas vacaciones de ensueño. ¡Descubre ahora la mejor escapada costera!

Guest favourite

Hotel room in Playa Coronado

4.89 out of 5 average rating, 35 reviews

My spot - Panamá

Indulge in charm at this adorable suite, boasting a picturesque pool view. Steps away from Panama's premier golf course and just 750m from the beach, it's an ideal retreat for nature lovers. Enjoy resort luxuries like four restaurants, a bar, golf, gym, beach club, tennis, and kids club. Whether relaxing or exploring, this sanctuary offers pampering and adventure in equal measure.

Superhost

Hotel room in Panamá

4.86 out of 5 average rating, 71 reviews

Corcho rooms #2 - king room with balconies

Enjoy charming “Corcho rooms” in the heart of touristic Casco Viejo district of Panama City. We carefully restored old colonial building and converted it to the restaurant an serviced guest rooms upstairs. “Corcho” is luckily situated in the central, restored part of Casco. Most of the building around are restored and the neighborhood is safe.

Guest favourite

Hotel room in Boquete

5 out of 5 average rating, 7 reviews

Deluxe King

Nestled in the vibrant heart of Boquete's downtown, REBEQUET Boutique Hotel is a charming retreat that combines history, comfort, and convenience. Originally established in 1983, our hotel has been thoughtfully renovated to offer a cozy and enhanced guest experience, making it the perfect base for your Boquete adventures.

Guest favourite

Private room in Bocas del Toro Province

5 out of 5 average rating, 7 reviews

MAR ONDA, the Eco-elegance Resort in Bluff Beach

Only a few steps to the beach, this resort was custom built to be in harmony with it's natural surroundings. Powered by the sun and watered by the rain, Mar onda is self-sufficient while still providing all the comforts of home. Enjoy fresh locally grown food and the comfort and craftsmanship of the accommodations.