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Apartment vacation rentals in Santa Cruz de la Sierra

Find and book unique apartments on Airbnb

Quick stats about apartment rentals in Santa Cruz de la Sierra

  • Total vacation rentals

    Explore 2,650 vacation rentals in Santa Cruz de la Sierra

  • Nightly prices starting at

    Santa Cruz de la Sierra vacation rentals start at $14 CAD per night before taxes and fees

  • Verified guest reviews

    Over 37,120 verified reviews to help you choose

  • Family-friendly vacation rentals

    680 properties offer extra space and kid-friendly amenities

  • Pet-friendly vacation rentals

    Find 630 rentals that welcome pets

  • Vacation rentals with a pool

    2,050 properties feature pools

  • Rentals with dedicated workspaces

    1,660 properties have a dedicated workspace

  • Wifi availability

    2,520 of Santa Cruz de la Sierra vacation rentals include wifi access

  • Popular amenities for guests

    Guests love Kitchen, Wifi, and Pool across Santa Cruz de la Sierra rentals

  • 4.7 Average rating

    Santa Cruz de la Sierra stays receive an average rating of 4.7 out of 5 from guests

Top-rated apartment rentals in Santa Cruz de la Sierra

Guests agree: these apartments are highly rated for location, cleanliness, and more.

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Top guest favourite
A modern living area is furnished with a gray sofa and a brown accent chair. A wooden coffee table sits on a textured rug in front of the sofa. Natural light floods in through large windows, illuminating the open layout that connects to an equipped kitchen.
Apartment in Santa Cruz de la Sierra
4.98 out of 5 average rating, 55 reviews

Luxury and comfort in every detail

This apartment combines luxury, style, and comfort in every detail. Designed as a boutique hotel, it offers a unique experience with impeccable finishes, an equipped kitchen, a cozy living room, spacious bedrooms, and a beautiful balcony to relax. Located in the heart of Equipetrol and a short walk from restaurants, shops and attractions. Perfect for business trips or relaxation, this modern and elegant space is ideal for relaxing and enjoying an unforgettable stay. You'll love it! Parking is included!

Guest favourite
Apartment in Santa Cruz de la Sierra
5.0 out of 5 average rating, 7 reviews

Skyline Luxury • Rooftop, Piscina, Billar & Lounge

Designed for discerning guests seeking a superior experience to a 5-star hotel. Located in Equipetrol, the most exclusive and secure area of Santa Cruz, this elegant apartment on the penultimate floor offers a double balcony with unique views! Premium amenities such as a sky pool, lounge, billiards, barbecues, a fully equipped gym, and more! Surrounded by the best restaurants, bars, cafes, theatres, shops and business centres. Ideal for executive travel, luxury getaways or unforgettable stays.

Top guest favourite
Apartment in Santa Cruz de la Sierra
5.0 out of 5 average rating, 8 reviews

Beautiful, spacious and unique apartment in the best area.

Create unforgettable memories in this unique and family home. Exceptional 122 m2 apartment in the heart of Equipetrol. Very quiet place to rest or work, but at the same time close to fun. You'll have an amazing stay! Spacious, modern, furnished and decorated apartment, A/C, Wi-Fi, 65" and 55" 4K Smart TVs, kitchen, 2 bedrooms, 3 bathrooms, private laundry and drying area, ample free parking at the entrance 24 hours a day. Beautiful pool and sauna. Large balcony with a lovely view of the city.

Top guest favourite
A modern living area features a comfortable sofa adorned with decorative pillows, alongside a sleek TV unit. Large windows offer panoramic city views, while two round mirrors enhance the brightness of the space. A small chair and indoor plant add a touch of decor.
Apartment in Santa Cruz de la Sierra
4.99 out of 5 average rating, 84 reviews

Equipetrol · 13th floor, great view and pool

✨ Enjoy a comfortable stay in Equipetrol, one of Santa Cruz’s most exclusive areas. The building offers shared areas: on the 4th floor you’ll find a spacious lounge with sofa, TV, air conditioning, and a pool table, along with a swimming pool and barbecue area; on the 17th floor you can enjoy the gym, another barbecue area, and city views. The apartment includes fast 293 Mbps Wi-Fi, an in-unit washer, 4K TV, air conditioning, and a fully equipped kitchen, ideal for business or leisure stays.

Guest favourite
A contemporary entryway featuring sleek, metallic walls and smooth marble flooring. A minimalist reception desk with soft ambient lighting displays the name 'NUU.' A large potted plant adds a touch of greenery, while well-placed lighting creates a bright atmosphere.
Apartment in Santa Cruz de la Sierra
4.93 out of 5 average rating, 81 reviews

apartment with an excellent view

Apartment located in the Equipetrol area. Located on the 13th floor, you'll enjoy stunning views in a comfortable and elegant atmosphere. This apartment has two bedrooms and two bathrooms, ideal for families or groups. It's fully equipped to make you feel at home. Among the building's amenities, you will find a cinema, a swimming pool, a barbecue area, an equipped gym, a playground, and parking for visitors. Easy access to restaurants, shops, and attractions.

Superhost
Apartment in Santa Cruz de la Sierra
5.0 out of 5 average rating, 5 reviews

POX | Green Tower - 21 | Luxury with Private Grill

Experience absolute luxury in this exclusive apartment on the 21st floor of the iconic Green Tower. Elegant design and panoramic city views. Enjoy a sophisticated living room, high-level dining room, fully equipped kitchen and a private balcony with its OWN BARBECUE, a unique luxury in the heights. The building offers a pool, sauna, social areas and 24/7 security, restaurants and bars. We'll make sure you have a memorable stay. Rest - Enjoy - Repeat Pox

Guest favourite
A comfortable sleeping area features a spacious bed adorned with soft pillows and a decorative throw. Warm bedside lamps illuminate the space, while large windows offer views of the surrounding cityscape and allow natural light to brighten the room.
Apartment in Santa Cruz de la Sierra
4.98 out of 5 average rating, 135 reviews

13° SmartLife - Luxury Equipetrol

Welcome to your sanctuary of sophistication and elegance at the top. This exceptionally cozy and stylish studio on the 13th floor invites you to experience luxury and comfort at their finest. Ready to experience the perfect combination of sophistication, comfort, and technology? Don't miss out on this unique opportunity. Book your stay at "13° SmartLife" and be seduced by the charm of this incomparable space! Your urban retreat awaits.

Guest favourite
Apartment in Santa Cruz de la Sierra
5.0 out of 5 average rating, 5 reviews

Luxury Studio|GreenTower|Pool & Parking|Equipetrol

Welcome to a space that combines elegance and comfort in the heart of Equipetrol. Surrounded by cafes, restaurants with authentic gastronomic proposals. Its strategic location will allow you to easily discover the best areas in the city. In this loft you will find a perfect balance between comfort, style and location. Ideal for sightseeing, a quiet getaway, or a business trip. We look forward to welcoming you for a unique stay.

Guest favourite
Apartment in Santa Cruz de la Sierra
4.93 out of 5 average rating, 30 reviews

POX: Green Tower 16th floor | Luxury and elegance - 2H

Live the POX experience! We present our largest apartment in the iconic Green Tower, the most exclusive and luxurious building in Santa Cruz. A fully equipped apartment for you to live a unique experience with your family or friends. Be dazzled by the best view of the city, 24/7 service and close to banks, restaurants, shopping malls, everything you need meters away. We'll make sure you have a great stay, welcome to POX!

Top guest favourite
A spacious bed is positioned against a large window, offering a view of the cityscape. Soft pillows and a neatly arranged blanket enhance the comfort of the sleeping area. A small rug lies on the floor, complementing the modern decor.
Apartment in Santa Cruz de la Sierra
4.89 out of 5 average rating, 152 reviews

Comfortable/modern studio apartment beautiful view 300Mbps

Welcome to the most active area of Santa Cruz! The price already includes all fees, you won't pay anything extra in the app. The apartment is a fully equipped, modern and comfortable studio. It has a double bed and a sofa bed in addition to a private bathroom, washer/dryer, kitchen and all the necessary appliances. Wi-Fi Internet, cable TV and NETFLIX. Close to supermarkets, the best restaurants in town and malls.

Top guest favourite
Apartment in Santa Cruz de la Sierra
5.0 out of 5 average rating, 20 reviews

Luxury Sky Elite| Piscina Infinita + Equipetrol

Enjoy a unique stay in the heart of Equipetrol, the best area of the city. Located on the 3rd floor, this modern and cozy apartment is fully equipped for short or long stays, designed to provide you with maximum comfort. Plus, enjoy upscale social areas with a pool, jacuzzi, movie theater, and an incredible view of the city from the common spaces that will make your experience even more special.

Guest favourite
Apartment in Santa Cruz de la Sierra
4.94 out of 5 average rating, 17 reviews

The best view of Santa Cruz

From this apartment in the best area of Santa Cruz (Equipetrol Norte, in the business center) you will have the best apartment with a pleasant climate. It is located on the 16th floor, unsurpassed views and sunsets. The whole group will enjoy easy access to supermarkets, restaurants, pharmacies, banks, transportation, paddle courts, etc. The Ventura mall is steps away from the apartment.

Popular amenities for Santa Cruz de la Sierra apartment rentals