
Guesthouse vacation rentals in Santa Cruz de la Sierra
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Top-rated guesthouses in Santa Cruz de la Sierra
Guests agree: these guesthouses are highly rated for location, cleanliness, and more.

Cozy family home in Santa Cruz de la Sierra
Family house of 320 square meters, on the second floor, with all the utensils and household clothes, wonderful views from its 30 meters of terrace. Ideal for families who want to have a quiet stay of any duration in the City of Santa Cruz de la Sierra. Very well connected with several bus lines that take you to the whole city and surroundings and very close to the Sanctuary of Cotoca. In the vicinity has all kinds of services, breakfasts, meals, markets, shops, etc..

Horizontal duplex in backyard of house with pool
Enjoy a semi-detached duplex (complete) in the backyard of my house. With its own entrance to the duplex, it shares an entrance to the property. Located in a safe and quiet area easily accessible, close to shops, markets, supermarkets, pharmacy, public transportation (blocks from the main avenues), by car 10 min. from the center, 5 min. from the Fexpo, 30 to 40 min. from the airport, 1 block walk from the society of engineers SIB, clinic Montalvo and Urbari.

Spacious house with a patio and parking
Casa de huéspedes, con patio amplio y parrilla (churrasquera), en una zona muy tranquila. Aire acondicionado en todos los ambientes, termotanque (agua caliente), Wi-Fi, amplia sala de estar. Suite con baño privado. Baño común, sofá-cama y sofa amplio en planta baja. (Pueden dormir cómodamente hasta 4 personas) Dirección: km 8, Barrio 14 de Agosto, Calle 3 Entre doble vía la guardia y radial 17 y medio

Room in the center, two minutes from everything!
Experience staying in the heart of Santa Cruz, just 3 blocks from the main square. Our bright and cozy room awaits you in a safe and lively area: museums, cafes, bars, shops and historic spots are just a few steps away. Ideal for those looking for comfort, style and an unbeatable location. With WiFi, thoughtful details for your rest and attention that will make you feel at home.

Complete centric apartment with garden and pool
Complete centric apartment with an enormous garden and pool. Private apartment with fully staffed kitchen, private bathroom and a bedroom with a queensized bed. You'll also have access to the big garden and the pool to relax and refresh yourself. By choosing our accommodation, you’re also supporting Ñañope, a local NGO dedicated to empowering household workers in Santa Cruz.

Lodge surrounded by nature in the city
We renewed our lodge for more comfort for our guests: Imagine a little house surrounded by trees and plants, easy to go and not far away from city center. We´re living on half a hectar and your new place for working o relaxing is inside this paradise. You´re completely independent from us, with all you need for taking a rest or work, including the swimming pool.

Double or Full Room in Downtown
New and elegant building located just 2 blocks from the main square, surrounded by shopping malls, restaurants, cafes, jewelry, perfumerias, perfumerias, it is located a couple of blocks from the house of culture, the cathedral, museums, 1 block, banks, 7 street market and various shops and locals.

Room #4 with private bathroom
Disfruta de la sencillez de este alojamiento tranquilo y céntrico. a 5 cuadras del monumento "El Cristo" a cinco minutos del centeo de la ciudad. a 50 mtrs. de av. principal Cristo redentor, donde pasan multiples lineas de transporte.

Private Apartment In Downtown
Welcome to our cozy guest house in one of the most beautiful and safe areas of the center! Just 6 blocks from Plaza 24 de Septiembre, our historic neighborhood offers you a unique experience.

Casa Portal Holístico # 1
Disfruta de este espacio místico de tranquilidad y armonía dónde tus noches serán restauradas y revitalizantes con la energía del Portal Holístico

Apartment-style room
Desconecta de tus preocupaciones en este espacio tan amplio y sereno.

department to share TamisaIII
Disfruta de la sencillez de este alojamiento tranquilo y céntrico.
Popular amenities for Santa Cruz de la Sierra guesthouses
Family-friendly guesthouses

Casa Portal Holístico # 1

Spacious house with a patio and parking

Complete centric apartment with garden and pool

Separate room with private bathroom

Horizontal duplex in backyard of house with pool

New independent house 5 rooms

Cozy family home in Santa Cruz de la Sierra

CASITA SURROUNDED BY NATURE
Guesthouses with a patio

Room #7 with private bathroom.

El Peregrino Inn 2

Mirador del Cielo - Boutique Apart Hotel 2

El Peregrino Inn 3

Room#6 with private bathroom

family home to share

El Peregrino Inn 4

Room #2 with private bathroom.
Other guesthouse vacation rentals

Casa Portal Holístico # 1

Spacious house with a patio and parking

Complete centric apartment with garden and pool

Separate room with private bathroom

Horizontal duplex in backyard of house with pool

New independent house 5 rooms

Cozy family home in Santa Cruz de la Sierra

CASITA SURROUNDED BY NATURE
Quick stats about guesthouse rentals in Santa Cruz de la Sierra

Total vacation rentals
Explore 50 vacation rentals in Santa Cruz de la Sierra

Nightly prices starting at
Santa Cruz de la Sierra vacation rentals start at $14 CAD per night before taxes and fees

Verified guest reviews
Over 350 verified reviews to help you choose

Pet-friendly vacation rentals
Find 10 rentals that welcome pets

Rentals with dedicated workspaces
20 properties have a dedicated workspace

Wifi availability
50 of Santa Cruz de la Sierra vacation rentals include wifi access

Popular amenities for guests
Guests love Kitchen, Wifi, and Pool across Santa Cruz de la Sierra rentals
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