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House vacation rentals in Santa Cruz de la Sierra

Find and book unique houses on Airbnb

Top-rated house rentals in Santa Cruz de la Sierra

Guests agree: these houses are highly rated for location, cleanliness, and more.

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Top guest favourite
Home in Centro
4.95 out of 5 average rating, 22 reviews

Modern Detached House with BBQ Area + Private Garage

💎 Modern, detached house in the heart of the city, located in the best and safest area of Santa Cruz, ideal for meetings 🥳. Just a short walk from 24-hour supermarkets, a shopping centre, hospitals, and pharmacies. It has 3 bedrooms (1 en suite), 4 full bathrooms, a spacious living and dining room, an equipped kitchen, and a barbecue grill in the private patio. Ideal for families or friends 🫂 looking for comfort and privacy, conveniently located to enjoy the best of the city in total comfort, style, and safety. Private parking for one vehicle

Superhost
A tranquil area is featured, showcasing a large, shimmering lagoon with palm trees lining the shore. Colorful, casual seating is visible on the sandy ground, providing spots for relaxation. The clear blue sky is dotted with a few clouds, enhancing the serene environment.
Home in Santa Cruz de la Sierra
4.87 out of 5 average rating, 23 reviews

Davezies House, A Unique Experience, Inland Sea

​Discover a sublime and captivating haven! A gem with two suites, including an impressive master suite. Enjoy spacious and refined spaces in the living-dining room and an open-concept gourmet kitchen. Relax by the pool or at the barbecue, perfect for creating memorable moments with family and friends. Air conditioning, TV and high-speed Wi-Fi—comfort is guaranteed. Access to elite areas: beach, restaurant, tiki bar, children's areas, and more We look forward to seeing you! Book now and secure your dates!

Guest favourite
An open living space features a light-colored sofa, coffee table, and accent chairs, complemented by an area rug. The dining area includes a table with high-backed chairs, while the kitchen is visible in the background, showcasing a well-lit and functional layout.
Home in Santa Cruz de la Sierra
4.96 out of 5 average rating, 97 reviews

Nice 2 bedroom house, the best rest.

Charming 2-bedroom house, equipped and decorated with timeless style. Located in a quiet and ultra-safe condominium, just 10 minutes from Viru Viru Airport and 30 minutes from downtown. Enjoy the condo's amenities: Swimming pool with slides Supermarket and ATM within walking distance Gym, saunas and jacuzzi to relax Walking circuits and tennis and soccer courts to stay active. Great for: Relaxing away from the hustle and bustle A stop after a flight Families and groups of friends.

Guest favourite
A bright living area is presented with two light-colored sofas adorned with colorful pillows. A wooden coffee table is centered between the sofas, while two stylish chairs are positioned nearby. Large windows allow natural light to fill the space, showcasing indoor plants.
Home in Santa Cruz de la Sierra
5 out of 5 average rating, 5 reviews

Beautiful house, private condominium

Hermosa casa de 320 m² construidos, ubicada en la Av. Milton Parra, esquina prolongación Av. Beni. Ideal para familias, cuenta con 2 dormitorios, una oficina y 1.5 baños. Dispone de un comedor espacioso y confortable, así como una cocina grande y bien equipada. Esta propiedad se encuentra en un condominio privado que ofrece áreas verdes y zonas de entretenimiento, tales como: - Piscina - Gimnasio - Cancha de fútbol de césped sintético - Cancha de baloncesto - Salón de eventos

Guest favourite
A spacious living area features a large white sectional sofa adorned with decorative pillows. A dark coffee table sits at the center, surrounded by a plush area rug. A pendant light hangs above, illuminating the space, while a piece of wall art adds a touch of color.
Home in Centro
4.94 out of 5 average rating, 34 reviews

Centrally located and spacious house 50 meters from 2nd Ring

One-story house with an unbeatable location and well-lit spaces. It has 4 spacious bedrooms (2 en suite). Fully furnished and very well decorated to make you feel at home. Located 50 meters from the 2nd Ring between Av. Alemana and Beni avenues, a safe and easily accessible residential area. Assisted by supermarkets, restaurants, such as the traditional “Casa del Camba” and others. Spacious social areas, living room, dining room, and barbecue. A fully-equipped kitchen.

Guest favourite
The two-story house features a terracotta roof and a welcoming entrance. The patio area is paved and includes potted plants. A carport is visible on the right side, providing shelter for vehicles. Surrounding greenery adds a touch of nature to the space.
Home in Santa Cruz de la Sierra
4.93 out of 5 average rating, 15 reviews

Comfortable and safe house SC

The house is very nice, comfortable and safe. Located 12 minutes from historic downtown Santa Cruz. Within walking distance are the Military Engineering School (EMI), the Military Aviation College and the Center cinema. In the surroundings you can find food businesses, pharmacies, mini supermarkets, health centers, urban park, squares and availability of transportation to all latitudes. Excellent location to rest with total peace of mind and security.

Guest favourite
An open-concept living area features stylish gray sofas arranged around a wooden coffee table. A dining table with multiple chairs occupies one side, complemented by modern pendant lighting. A fully equipped kitchen is visible, showcasing wood cabinetry and a neutral color palette.
Home in Santa Cruz de la Sierra
5 out of 5 average rating, 7 reviews

Modern Comfy House

Relax with the whole family at this peaceful place to stay. Located between 6 and 7th ring. Hermosa galera con churrasquera! Pull out couch along with an iron provided! No need to worry about wrinkled clothes. Bus stop, pharmacy, hospital and park located all within walking distance. Top security containing a contact alarm and an electrical wire built on top of the fence, so you can enjoy your vacation worry free.Air condition and heating !!!

Superhost
Home in Centro
5 out of 5 average rating, 3 reviews

Suite for 5 with balcony and hammock | Top area

Suite privada amplia ubicada en el segundo piso de una casa, ideal para 5 personas. Cuenta con dormitorio con dos camas de dos plazas y sofá cama, baño privado, vestidor, comedor privado y balcón con hamaca. Incluye Smart TV 43”, WiFi, microondas, frigobar y utensilios. Además, la propiedad ofrece áreas comunes compartidas como cocina equipada con horno, lavadora, salas, churrasquera, patio, parqueo y espacios recreativos (ping pong y futbolín).

Superhost
The serene pool area is highlighted by clear blue waters, surrounded by lush palm trees and tropical vegetation. Sunlight reflects off the water's surface, offering a calm and inviting atmosphere for relaxation. The space provides access to nearby facilities and is designed for leisure.
Home in Santa Cruz de la Sierra
4.92 out of 5 average rating, 24 reviews

Condominium house near Fexpocruz for 8

New house, cozy, ideal for a large family, one floor with four bedrooms and four bathrooms, garden, gallery and barbecue to enjoy the outdoors. Enjoy the security of a beautiful condominium with multi-functional courts, a children's playground, a large swimming pool, barbecues with a cabin, a micro market, and private streets with 24-hour security. Located very close to Fexpocruz, a few minutes from downtown and Equipetrol.

Superhost
A spacious room is featured, showcasing a large bed with light-colored bedding. A wooden frame holds a large mirror above the bed. A television sits on a wooden dresser, and a small table with a chair is positioned nearby. Light fixtures provide ample illumination.
Home in Santa Cruz de la Sierra
4.73 out of 5 average rating, 30 reviews

Cozy House, WIFI, A/C, Washing Machine

Are you passing through Santa Cruz or do you plan to stay several days in the city? Then enjoy the simplicity of this quiet and central accommodation. Located 2 blocks from the Expocruz fair and minutes from any important point in the city, here you can rest quietly to start the next day with all your energy. We have 2 bedrooms, a kitchen with all amenities, laundry and parking for your vehicle.

Guest favourite
A serene outdoor area features a swing adorned with a fabric covering, surrounded by lush greenery. Decorative stone paths lead through a well-maintained lawn, complemented by minimalist landscaping elements, including potted plants and a grilling area built into the wall.
Home in Santa Cruz de la Sierra
4.91 out of 5 average rating, 33 reviews

Minimalista y vintage

Escápate a esta casa minimalista con toque vintage rodeada de naturaleza, dentro de un complejo completo con piscina, cancha polideportiva, tenis y sauna. Perfecto para disfrutar un fin de semana inolvidable en familia a solo 1 0 minutos del aeropuerto y 20 min de la ciudad. Cuenta con parrillero y jacuzzi dentro de la casa y totalmente automatizada

Superhost
A private pool is framed by lush greenery and vibrant flowers, creating a serene and secluded environment. The clear blue water reflects the sky, and the pool's stone edges blend harmoniously with the natural surroundings.
Home in Santa Cruz de la Sierra
4.83 out of 5 average rating, 6 reviews

House with a pool

Hermosa casa con piscina privada 24/7, ubicada en un barrio tranquilo y seguro. Cuenta con 4 habitaciones (3 en suite), 4 baños, cocina equipada, WiFi rápido y amplios espacios para disfrutar. Se permiten mascotas. Ideal para familias o grupos. Se permiten fiestas, respetando a los vecinos y haciéndose responsables de cualquier daño. 🌴🏡

Popular amenities for Santa Cruz de la Sierra house rentals

Quick stats about house rentals in Santa Cruz de la Sierra

  • Total vacation rentals

    Explore 470 vacation rentals in Santa Cruz de la Sierra

  • Nightly prices starting at

    Santa Cruz de la Sierra vacation rentals start at $14 CAD per night before taxes and fees

  • Verified guest reviews

    Over 2,290 verified reviews to help you choose

  • Family-friendly vacation rentals

    190 properties offer extra space and kid-friendly amenities

  • Pet-friendly vacation rentals

    Find 150 rentals that welcome pets

  • Vacation rentals with a pool

    150 properties feature pools

  • Rentals with dedicated workspaces

    200 properties have a dedicated workspace

  • Wifi availability

    420 of Santa Cruz de la Sierra vacation rentals include wifi access

  • Popular amenities for guests

    Guests love Kitchen, Wifi, and Pool across Santa Cruz de la Sierra rentals

  • 4.7 Average rating

    Santa Cruz de la Sierra stays receive an average rating of 4.7 out of 5 from guests

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