
Hotel vacation rentals in Santa Cruz
Find and book unique hotels on Airbnb
Top-rated hotels in Santa Cruz
Guests agree: these hotels are highly rated for location, cleanliness, and more.
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Vacation rentals for every style
Get the amount of space that is right for you.
Popular amenities for Santa Cruz hotels
Family-friendly hotels
Guest favourite

Private room in El Chaltén
4.88 out of 5 average rating, 105 reviewsCozy Room & WC private, Breakfast. In Hostel.

Hotel room in Lago Argentino Department
Unique and natural landscape
Superhost

Casa particular in Lago Argentino Department
5 out of 5 average rating, 6 reviewsLas Pircas del Sur

Hotel room in El Calafate
New place to stayStandard Double Bedroom

Hotel room in El Calafate
Double room

Hotel room in Perito Moreno
New place to stayHotel Kelman

Shared room in El Chaltén
El Kamaruco Hostel
Superhost

Private room in El Chaltén
4.8 out of 5 average rating, 107 reviewsBeautiful Room & WC private, Breakfast. In Hostel.
Hotels with a pool

Hotel room in El Calafate
4.67 out of 5 average rating, 9 reviewsDouble room with a view of the hill

Hotel room in El Chaltén
5 out of 5 average rating, 8 reviewsDestino Sur Room 3-4-5 pax

Hotel room in El Chaltén
Destination South Double Premium

Hotel room in El Chaltén
Destino Sur Superior Double

Hotel room in El Calafate
5 out of 5 average rating, 3 reviewsDouble room

Hotel room in El Chaltén
4.75 out of 5 average rating, 12 reviewsDestination South Double Standard
Hotels with a patio

Shared room in El Chaltén
4.5 out of 5 average rating, 4 reviewsExcellent base for your hike

Hotel room in El Chaltén
4.57 out of 5 average rating, 7 reviewsBedroom 18

Hotel room in El Calafate
Double room with breakfast

Hotel room in El Calafate
4.67 out of 5 average rating, 6 reviewsKau Kaleshen Double Room

Hotel room in El Chaltén
4.62 out of 5 average rating, 55 reviewsHotel Double Room

Hotel room in El Chaltén
4.79 out of 5 average rating, 14 reviewsPoincenot Double Standard

Casa particular in El Chaltén
4.42 out of 5 average rating, 12 reviewsMono environment 2

Hotel room in El Chaltén
4.55 out of 5 average rating, 22 reviewsPunta Sur in Lago del Desierto 1 TWIN
Destinations to explore
- Rentals with a firepit Santa Cruz
- Private suite rentals Santa Cruz
- Rentals with outdoor seating Santa Cruz
- Rentals with breakfast Santa Cruz
- Beachfront rentals Santa Cruz
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- Waterfront rentals Santa Cruz
- Vacation home rentals Santa Cruz
- Rentals with a patio Santa Cruz
- Loft rentals Santa Cruz
- Rentals with lake access Santa Cruz
- Condo rentals Santa Cruz
- Rentals with a fireplace Santa Cruz
- Serviced apartment rentals Santa Cruz
- Rentals with a washer and dryer Santa Cruz
- Bed and breakfasts Santa Cruz
- Tiny house rentals Santa Cruz
- Hostel rentals Santa Cruz
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- Rentals with a hot tub Santa Cruz
- Hotel rentals Argentina