
House vacation rentals in Simpsonville
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Top-rated house rentals in Simpsonville
Guests agree: these houses are highly rated for location, cleanliness, and more.

The Greenville Nest - Retreat & Relaxation Home
This beautifully one-level home offers 3 queen beds and 2 baths, accommodating up to 6 guests. Centrally located in a peaceful neighborhood. 8-minute drive to GSP airport, 15-minute drive to downtown Greenville, minutes from I-85/385, and minutes from Woodruff and Pelham Rd. You'll appreciate the easy access to food delivery and restaurants. Enjoy a stylish Experience for entertaining, working, and relaxing with high-speed Wi-Fi. Quiet and safe with an enjoyable private screened porch and Grill.

Fenced in Yard, 2 Queen Beds, Downtown!
Hard to beat this amazing value! Nestled on a quiet street 5 minutes from downtown, this 2bed/1bath property is perfect for your visit to Greenville. Each bedroom has a queen bed and plenty of closet space with hangers. Out back, there's a spacious deck to relax on, and the property has a fenced in yard which would be ideal for your curious furry friend. This property is minutes from hospitals & interstate 85. Ideal for work travelers, or simply curious visitors. There's a driveway for parking.

Spectacular home 1 mile from Main St Greenville!
Enjoy your stay in this charming up to date house 1 mile from Main St Greenville! Take a walk through the Historic Pinckney district on your way to Greenville’s museums, restaurants, theaters, and stunning Reedy River Falls Park. Easy access to the Swamp Rabbit biking and walking trail, and just 4 blocks from the upcoming Unity Park. House is located on quiet residential street with private driveway. Relax on rocking chairs on front porch or around a portable fire pit in large backyard.

Designer Modern Retreat Near Downtown Greenville
Welcome to your Greenville getaway! Minutes to downtown, GetawayGVL is a designer 1950s ranch that offers the conveniences of a hotel with the comforts of home. This bright and airy 3BR, 1.5BA mid-century modern oasis boasts a stunning outdoor space with yard games for entertaining, a dedicated desk for working, and an updated kitchen for cooking. You're only minutes away from a walk on the Swamp Rabbit Trail, dinner by the Reedy River, or a concert at The Well! Book your getaway today!

3BR Retreat Near Augusta Rd & Downtown w/ Patio
Tucked away just off Augusta Rd near Downtown Greenville, Flora Sanctuary is your custom oasis to relax and recharge. At our home, you are less than 2 miles from I-85 for easy access to all the upstate has to offer. Our home is thoughtfully designed to provide an upscale experience for our guests both inside and out. We are: ~Less than a mile from Greenville Country Club Chanticleer Golf Course ~Less than 5 miles from N Main St and Falls Park ~5 miles from Bon Secours Wellness Arena

Near Downtown! 1 Bed Minutes to Everything!
Cozy 1 Bedroom duplex within walking distance to restaurants and shopping. One mile to Bon Secours Wellness Arena and 3 minute drive to downtown Greenville. 1.5 Miles to Bob Jones University. Perfect for a business traveler or couple for a getaway trip to our great city! Pet friendly, Free parking, king sized bed, extra comfy linens, clean towels, and a comfortable atmosphere to relax during your stay. Space comes with VERY FAST and FREE WIFI, SMART TV and a fully stocked kitchen.

Modern Farmhouse in Downtown Simpsonville, SC
Newly renovated two-bedroom home located in downtown Simpsonville, within easy walking distance of an excellent variety of restaurants, shops and places of interest. A spacious private balcony, leading off from the main bedroom suite overlooks a peaceful backyard... a great place to relax outdoors! The kitchen is fully equipped for preparing great meals. Our home is thoroughly and professionally cleaned & sanitized. ***Please note there is a train that runs midday and late at night.

Simpsonville Southern Comfort
Welcome to Simpsonville Southern Comfort! Our home offers a comfortable, completely remodeled space with all of the amenities of home to make your stay enjoyable. This home is in a GREAT location just a 5-minute drive from the conveniences of the Five Forks area, and a short 7-minute drive to the enjoyment of The Square in Downtown Simpsonville. Our home is also a quick 20-minute drive from GSP International Airport, and 20 minutes from Downtown Greenville. Enjoy your stay!

Claire's tearoom / artist suite
One bedroom suite, under the sun-room with 4 windows overlooking the private garden; private entrance and completely separate from the main house; Individual mini split A/C unit in suite for your ultimate comfort; Huge working desk with plenty natural lights. Enjoy your morning tea or coffee in the garden; Relaxing and reading on the custom build banquette; super comfy Queen Size bed (Brand new mattress as of March 2024); separate area of bathroom, shower, sink and KITCHENETTE.

Family & Pet Friendly Home - Sleeps 8
Our home is absolutely perfect for entertaining, work and relaxation. Enjoy fast wifi and free coffee. Connect over a meal at our spacious dining table. Families will love the large, fenced-in backyard, toys and board games in our huge rec room, complete with ping pong table! Quiet and easy connections to Greenville & Simpsonville. Only 5 mins from Discovery Island Waterpark. Community park and playground accessible with lots of space to roam with family or pets.

Cozy Treehouse
Situated at the back of a wooded 2 acre lot, only 10 minutes from downtown Greenville, this is a little oasis in the city! While most treehouses take you on a "roughing it" adventure, Cozy Treehouse is the glamping version of treehouses, boasting 9' ceilings, 1.5 baths, 3 LED TV's and many outdoor living options. If you are looking for a unique getaway just minutes from one of the top growing cities in the south, Cozy Treehouse is the perfect destination for you.

Willow Oak Retreat // Comfy beds & Large backyard!
Welcome to Willow Oak Retreat! We cant wait to host you! - Private deck with grill and eating area - Fully equipped kitchen with tea, coffee and snacks - Safe and quiet neighborhood - 1 mile to all of downtown Simpsonville's restaurants and shops - 1 mile to huge park including playground, tennis, basketball and farmers market. - Short 20 minute drive to downtown Greenville - Perfect for families and those traveling for work!
Popular amenities for Simpsonville house rentals
House rentals with a pool

Upstate Getaway at the Relaxing Ranch

HOT TUB Sleeps 11 Gameroom Cozy Getaway

The Wright Place! 25/min DT G-Ville. Pool/Hottub.

Shalom House with Pool near DT Greer SC

Pickleball, Ping-Pong, King beds, BonFire Nights!

Spacious 3 BR house with private backyard oasis.

Greenville Bungalow w/ Stock Tank Pool + Fire pit

Brand New Charming home in heart of Moore
Weekly house rentals

18 Hidden Gem - Private Home - 3 BDRM In 5 Forks

Modern Cottage in the Woods w/ Hot Tub & Firepit

Mountain Villa 15min from Downtown Greenville

Bohemian Bungalow

Spacious Retreat w/ Game Room & Outdoor Oasis

West End Cottage

Southern Charm Townhome

Fountain Inn on Main St
Private house rentals

Modern+Treetop+Terrace+Retreat

Mauldin 3bdroom-Maverick Ranch STR23-000002

Downtown Simpsonville/5 Private Bedrooms/Pergola

The Taylor House

Luxury spacious 4 bedroom home

House Frieda

3BR Home • Near Bridgeway, I-85 & GSP•Pet Friendly

Heart of Fountain Inn: 2BR Gem
When is the best time to visit Simpsonville?
| Month | Jan | Feb | Mar | Apr | May | Jun | Jul | Aug | Sep | Oct | Nov | Dec |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Avg. price | $178 CAD | $173 CAD | $169 CAD | $167 CAD | $175 CAD | $175 CAD | $164 CAD | $177 CAD | $171 CAD | $175 CAD | $167 CAD | $184 CAD |
| Avg. temp | 6 °C | 8 °C | 12 °C | 16 °C | 20 °C | 25 °C | 27 °C | 26 °C | 23 °C | 17 °C | 11 °C | 7 °C |
Quick stats about house rentals in Simpsonville

Total vacation rentals
Explore 70 vacation rentals in Simpsonville

Nightly prices starting at
Simpsonville vacation rentals start at $41 CAD per night before taxes and fees

Verified guest reviews
Over 2,180 verified reviews to help you choose

Family-friendly vacation rentals
40 properties offer extra space and kid-friendly amenities

Pet-friendly vacation rentals
Find 20 rentals that welcome pets

Rentals with dedicated workspaces
40 properties have a dedicated workspace

Wifi availability
70 of Simpsonville vacation rentals include wifi access

Popular amenities for guests
Guests love Kitchen, Wifi, and Pool across Simpsonville rentals

4.8 Average rating
Simpsonville stays are highly rated by guests—averaging 4.8 out of 5!
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