
House vacation rentals in Simpsonville
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Top-rated house rentals in Simpsonville
Guests agree: these houses are highly rated for location, cleanliness, and more.

Quaint-n-Quirky Downtown Greer Home
This Quaint & Quirky home is the ideal base to explore Upstate SC! The perfect balance of old and new for your group or family. Located within a short distance to the small city life or scenic country views. Walking distance to downtown Greer, half mile from Greer City Park, 15 min from GSP Airport, and 13 min from BMW. Take a day trip to downtown Greenville or Spartanburg with only a 30 min drive to either! Checkout “T&S’s Guidebook - Greer, South Carolina” for our local recommendations!

Modern Wooded Retreat
Come enjoy this modern, 1.6 acre retreat! Relax with the whole family in a place you'll never want to leave. Located 5 min. to downtown TR and less than 20 min to downtown Greenville! Roast marshmallows by the firepit, play yard jenga, connect 4 and cornhole in the fully fenced, dog friendly back yard. Close to the swamp rabbit trail, and centrally located to lakes, hiking, fishing and exciting nightlife. Let us host you, while you explore everything Greenville and Travelers Rest have to offer.

Greenville GEM Luxurious Retreat in Prime Location
Beautifully renovated 3 beds, 2 baths haven! This gem is a tranquil & stylish retreat, blending modern & cozy charm. Spacious bedrooms, each with plush bedding and storage. Two Bathrooms with soaking tub and a spacious walk-in shower. Cozy living room with a fireplace, TV, and comfy seating. Fully equipped kitchen, Wi-Fi, Private deck and gazebo, fenced yard. Close to the city's best attractions, dining, and entertainment options. This is the perfect home base for your Greenville adventures.

Spectacular home 1 mile from Main St Greenville!
Enjoy your stay in this charming up to date house 1 mile from Main St Greenville! Take a walk through the Historic Pinckney district on your way to Greenville’s museums, restaurants, theaters, and stunning Reedy River Falls Park. Easy access to the Swamp Rabbit biking and walking trail, and just 4 blocks from the upcoming Unity Park. House is located on quiet residential street with private driveway. Relax on rocking chairs on front porch or around a portable fire pit in large backyard.

Chic 3/2 Near Downtown Gvl, Greer & Travelers Rest
Welcome to Taylor's Grove East, a brand-new 3-bedroom, 2-bathroom home located Taylor's, Greenville's Eastside neighborhood . Boasting a modern yet cozy design, this home combines design staples with just the right pop of color. Perfect for up to 6 guests, its strategic location is a dream for explorers. Downtown Greenville, Greer, and Traveler's Rest are all within a swift 20-minute drive. Experience the charm of the Upstate and return to unwind in style. Your relaxing gateway awaits.

Modern Farmhouse in Downtown Simpsonville, SC
Newly renovated two-bedroom home located in downtown Simpsonville, within easy walking distance of an excellent variety of restaurants, shops and places of interest. A spacious private balcony, leading off from the main bedroom suite overlooks a peaceful backyard... a great place to relax outdoors! The kitchen is fully equipped for preparing great meals. Our home is thoroughly and professionally cleaned & sanitized. ***Please note there is a train that runs midday and late at night.

Simpsonville Southern Comfort
Welcome to Simpsonville Southern Comfort! Our home offers a comfortable, completely remodeled space with all of the amenities of home to make your stay enjoyable. This home is in a GREAT location just a 5-minute drive from the conveniences of the Five Forks area, and a short 7-minute drive to the enjoyment of The Square in Downtown Simpsonville. Our home is also a quick 20-minute drive from GSP International Airport, and 20 minutes from Downtown Greenville. Enjoy your stay!

Cozy Swamp Rabbit - Sans Souci Greenville Furman
Welcome to Greenville - 1500 sq ft mill home in Sans Souci area. 5 min to downtown Greenville, quiet area - 10 min to Travelers Rest w bakeries, restaurants, shops, Furman. Half-mile to famous Swamp Rabbit Trail / Cafe (bike/walk). Explore GVL on the two provided bikes. Work here - fast wi-fi. Charge EV using 14-50 AMP port Tesla / other EVs. Hike with SC State Park - All Park Pass - free entry to all 47 SC State Parks. Create an adventure, visit or test-live in Greenville.

Updated 4 BR Family Friendly Escape w/ Swingset
>>Experienced SuperHosts!<< This stylishly updated home is conveniently located just 3 minutes from the shopping & dining in Downtown Simpsonville & convenient to everything that Greenville has to offer. With 4 bedrooms, 2 full baths & a fenced in yard, this house is perfect for families, groups of friends, and workers on assignment in the area! Located in a safe & quiet neighborhood just 20 minutes from downtown Greenville & 5 minutes to all of your daily needs.

Shalom House with Pool near DT Greer SC
Find a place of peace in Greer, SC at the Shalom House! • Located in a quiet neighborhood • 0.7 miles to historic downtown Greer, SC and Greer Park (accessible by walking 10min) • 12 min to GSP International Airport • 20 min to Greenville city center • 20 min to Spartanburg • 10 min to Lake Cunningham, 17 min to Lake Robinson • Yoga 3 blocks away • Tons of noteworthy restaurants and shops nearby Book now and enjoy this beautiful home! Note: Our pool OPENS May 1st

Family & Pet Friendly Home - Sleeps 8
Our home is absolutely perfect for entertaining, work and relaxation. Enjoy fast wifi and free coffee. Connect over a meal at our spacious dining table. Families will love the large, fenced-in backyard, toys and board games in our huge rec room, complete with ping pong table! Quiet and easy connections to Greenville & Simpsonville. Only 5 mins from Discovery Island Waterpark. Community park and playground accessible with lots of space to roam with family or pets.

Cozy Treehouse
Situated at the back of a wooded 2 acre lot, only 10 minutes from downtown Greenville, this is a little oasis in the city! While most treehouses take you on a "roughing it" adventure, Cozy Treehouse is the glamping version of treehouses, boasting 9' ceilings, 1.5 baths, 3 LED TV's and many outdoor living options. If you are looking for a unique getaway just minutes from one of the top growing cities in the south, Cozy Treehouse is the perfect destination for you.
Popular amenities for Simpsonville house rentals
House rentals with a pool

Upstate Getaway at the Relaxing Ranch

HOT TUB Sleeps 11 Gameroom Cozy Getaway

The Wright Place! 25/min DT G-Ville. Pool/Hottub.

Getaway Home w/ Private Hot Tub & Fenced Huge Pool

Stylist New Woodruff Home.

Greenville Bungalow w/ Stock Tank Pool + Fire pit

Spacious 3 BR house with private backyard oasis.

Brand New Charming home in heart of Moore
Weekly house rentals

Fully Furnished Cozy Cottage

Mountain View Hideaway

Renovated Tiny Ranch

Luxury spacious 4 bedroom home

House Frieda

Cozy Country Cottage edge of town.

Cozy Charming Townhome

Southern Charm Townhome
Private house rentals

Family home • Large yard and pets

18 Hidden Gem - Private Home - 3 BDRM In 5 Forks

Game On! 4BR w/ King & Fireplace

Cozy 2BR Cottage | Close to Clemson & GVL

Downtown Simpsonville/5 Private Bedrooms/Pergola

Cozy home in downtown TR

Duplex near hospitals & downtown monthly discount.

The Little Queen
Quick stats about house rentals in Simpsonville
Total rentals
70 properties
Nightly prices starting at
$42 CAD before taxes and fees
Total number of reviews
2.2K reviews
Family-friendly rentals
40 properties are a good fit for families
Pet-friendly rentals
20 properties allow pets
Rentals with dedicated workspaces
40 properties have a dedicated workspace
Destinations to explore
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- Family-friendly rentals Simpsonville
- Rentals with a fireplace Simpsonville
- Rentals with a patio Simpsonville
- Rentals with outdoor seating Simpsonville
- Rentals with a washer and dryer Simpsonville
- Rentals with a firepit Simpsonville
- Pet-friendly rentals Simpsonville
- House rentals Greenville County
- House rentals South Carolina
- House rentals United States
- Gorges State Park
- Table Rock State Park
- Chimney Rock State Park
- Tugaloo State Park
- Tryon International Equestrian Center
- Lake Lure Beach and Water Park
- Jump Off Rock
- Victoria Valley Vineyards
- Discovery Island
- Carl Sandburg Home National Historic Site
- Haas Family Golf
- Saint Paul Mountain Vineyards
- City Scape Winery
- Enoree River Vineyards and Winery
- Burntshirt Vineyards
- Overmountain Vineyards
- Wellborn Winery
- Russian Chapel Hills Winery