House vacation rentals in Simpsonville

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Top-rated house rentals in Simpsonville

Guests agree: these houses are highly rated for location, cleanliness, and more.

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Guest favourite
A screened porch is highlighted, featuring comfortable wooden seating with light cushions and a matching table. Natural light is allowed through large windows and a skylight, providing a view of the surrounding greenery. A small potted plant decorates the table, enhancing the relaxing atmosphere.
Home in Greenville
4.96 out of 5 average rating, 132 reviews

The Greenville Nest - Retreat & Relaxation Home

This beautifully one-level home offers 3 queen beds and 2 baths, accommodating up to 6 guests. Centrally located in a peaceful neighborhood. 8-minute drive to GSP airport, 15-minute drive to downtown Greenville, minutes from I-85/385, and minutes from Woodruff and Pelham Rd. You'll appreciate the easy access to food delivery and restaurants. Enjoy a stylish Experience for entertaining, working, and relaxing with high-speed Wi-Fi. Quiet and safe with an enjoyable private screened porch and Grill.

Superhost
A cozy living area features a leather couch adorned with pink cushions, positioned near a decorative glass coffee table. Sunlight filters through the windows, illuminating a flat-screen television above a white mantel. A small side table and a bookshelf add functional charm to the space.
Home in Greenville
4.82 out of 5 average rating, 166 reviews

Fenced in Yard, 2 Queen Beds, Downtown!

Hard to beat this amazing value! Nestled on a quiet street 5 minutes from downtown, this 2bed/1bath property is perfect for your visit to Greenville. Each bedroom has a queen bed and plenty of closet space with hangers. Out back, there's a spacious deck to relax on, and the property has a fenced in yard which would be ideal for your curious furry friend. This property is minutes from hospitals & interstate 85. Ideal for work travelers, or simply curious visitors. There's a driveway for parking.

Top guest favourite
The front of the house is showcased with a white exterior and a welcoming porch. Two rocking chairs are positioned on the porch, surrounded by planters displaying seasonal flowers. A well-maintained pathway leads to the entrance, framed by decorative brick steps and a railing.
Home in Greenville
4.97 out of 5 average rating, 237 reviews

Spectacular home 1 mile from Main St Greenville!

Enjoy your stay in this charming up to date house 1 mile from Main St Greenville! Take a walk through the Historic Pinckney district on your way to Greenville’s museums, restaurants, theaters, and stunning Reedy River Falls Park. Easy access to the Swamp Rabbit biking and walking trail, and just 4 blocks from the upcoming Unity Park. House is located on quiet residential street with private driveway. Relax on rocking chairs on front porch or around a portable fire pit in large backyard.

Top guest favourite
Home in Greenville
4.99 out of 5 average rating, 190 reviews

Designer Modern Retreat Near Downtown Greenville

Welcome to your Greenville getaway! Minutes to downtown, GetawayGVL is a designer 1950s ranch that offers the conveniences of a hotel with the comforts of home. This bright and airy 3BR, 1.5BA mid-century modern oasis boasts a stunning outdoor space with yard games for entertaining, a dedicated desk for working, and an updated kitchen for cooking. You're only minutes away from a walk on the Swamp Rabbit Trail, dinner by the Reedy River, or a concert at The Well! Book your getaway today!

Guest favourite
An open living space features a vibrant accent wall adorned with botanical wallpaper. A custom emerald green sofa and accent chair provide seating around a rustic wooden coffee table. The kitchen and dining area are visible, showcasing an inviting atmosphere with modern appliances and ample seating.
Home in Pleasant Valley
4.96 out of 5 average rating, 146 reviews

3BR Retreat Near Augusta Rd & Downtown w/ Patio

Tucked away just off Augusta Rd near Downtown Greenville, Flora Sanctuary is your custom oasis to relax and recharge. At our home, you are less than 2 miles from I-85 for easy access to all the upstate has to offer. Our home is thoughtfully designed to provide an upscale experience for our guests both inside and out. We are: ~Less than a mile from Greenville Country Club Chanticleer Golf Course ~Less than 5 miles from N Main St and Falls Park ~5 miles from Bon Secours Wellness Arena

Guest favourite
A comfortable living space features a gray sofa adorned with decorative pillows, a wooden coffee table, and a small shelf displaying plants and artwork. Light enters through multiple windows, illuminating the dining area equipped with a wooden table and chairs in the background.
Home in Greenville
4.81 out of 5 average rating, 193 reviews

Near Downtown! 1 Bed Minutes to Everything!

Cozy 1 Bedroom duplex within walking distance to restaurants and shopping. One mile to Bon Secours Wellness Arena and 3 minute drive to downtown Greenville. 1.5 Miles to Bob Jones University. Perfect for a business traveler or couple for a getaway trip to our great city! Pet friendly, Free parking, king sized bed, extra comfy linens, clean towels, and a comfortable atmosphere to relax during your stay. Space comes with VERY FAST and FREE WIFI, SMART TV and a fully stocked kitchen.

Superhost
A contemporary living area features a comfortable gray sofa with accent pillows, positioned beside a coffee table. A flat-screen TV is mounted on a shiplap wall above an electric fireplace. Natural light floods the space through window coverings, illuminating the stylish decor.
Home in Simpsonville
4.96 out of 5 average rating, 130 reviews

Modern Farmhouse in Downtown Simpsonville, SC

Newly renovated two-bedroom home located in downtown Simpsonville, within easy walking distance of an excellent variety of restaurants, shops and places of interest. A spacious private balcony, leading off from the main bedroom suite overlooks a peaceful backyard... a great place to relax outdoors! The kitchen is fully equipped for preparing great meals. Our home is thoroughly and professionally cleaned & sanitized. ***Please note there is a train that runs midday and late at night.

Top guest favourite
A bright living room features two leather sofas positioned around a cozy area rug. Large windows provide ample natural light, with a mounted TV above a wooden mantel. Decorative wall frames add character to the space, complemented by a soft throw draped over one of the sofas.
Home in Simpsonville
4.95 out of 5 average rating, 153 reviews

Simpsonville Southern Comfort

Welcome to Simpsonville Southern Comfort! Our home offers a comfortable, completely remodeled space with all of the amenities of home to make your stay enjoyable. This home is in a GREAT location just a 5-minute drive from the conveniences of the Five Forks area, and a short 7-minute drive to the enjoyment of The Square in Downtown Simpsonville. Our home is also a quick 20-minute drive from GSP International Airport, and 20 minutes from Downtown Greenville. Enjoy your stay!

Superhost
The suite features a bright and airy layout, with two windows allowing natural light to illuminate the space. A stylish working desk is placed beside a comfortable sitting area, surrounded by built-in shelving that showcases decorative elements and plants.
Home in Travelers Rest
4.85 out of 5 average rating, 621 reviews

Claire's tearoom / artist suite

One bedroom suite, under the sun-room with 4 windows overlooking the private garden; private entrance and completely separate from the main house; Individual mini split A/C unit in suite for your ultimate comfort; Huge working desk with plenty natural lights. Enjoy your morning tea or coffee in the garden; Relaxing and reading on the custom build banquette; super comfy Queen Size bed (Brand new mattress as of March 2024); separate area of bathroom, shower, sink and KITCHENETTE.

Top guest favourite
A calming bedroom features a spacious bed with crisp white linens and decorative pillows. A ceiling fan enhances airflow, while a large TV is mounted on the wall. A potted plant adds a touch of greenery, and soft light is provided by bedside lamps.
Home in Greenville
4.99 out of 5 average rating, 142 reviews

Family & Pet Friendly Home - Sleeps 8

Our home is absolutely perfect for entertaining, work and relaxation. Enjoy fast wifi and free coffee. Connect over a meal at our spacious dining table. Families will love the large, fenced-in backyard, toys and board games in our huge rec room, complete with ping pong table! Quiet and easy connections to Greenville & Simpsonville. Only 5 mins from Discovery Island Waterpark. Community park and playground accessible with lots of space to roam with family or pets.

Top guest favourite
The treehouse structure features a distinctive A-frame design with large glass paneling allowing for abundant natural light. Surrounded by trees, an outdoor deck with seating complements the lush woodland setting. The rooftop deck above adds to the unique architectural appeal.
Home in Greenville
4.99 out of 5 average rating, 231 reviews

Cozy Treehouse

Situated at the back of a wooded 2 acre lot, only 10 minutes from downtown Greenville, this is a little oasis in the city! While most treehouses take you on a "roughing it" adventure, Cozy Treehouse is the glamping version of treehouses, boasting 9' ceilings, 1.5 baths, 3 LED TV's and many outdoor living options. If you are looking for a unique getaway just minutes from one of the top growing cities in the south, Cozy Treehouse is the perfect destination for you.

Guest favourite
A cozy living space features rich wooden floors and a white brick fireplace as a focal point. Comfortable seating is arranged in front of the fireplace, with soft natural light filtering through the large windows. The adjoining kitchen is visible, showcasing wooden cabinetry.
Home in Simpsonville
4.97 out of 5 average rating, 248 reviews

Willow Oak Retreat // Comfy beds & Large backyard!

Welcome to Willow Oak Retreat! We cant wait to host you! - Private deck with grill and eating area - Fully equipped kitchen with tea, coffee and snacks - Safe and quiet neighborhood - 1 mile to all of downtown Simpsonville's restaurants and shops - 1 mile to huge park including playground, tennis, basketball and farmers market. - Short 20 minute drive to downtown Greenville - Perfect for families and those traveling for work!

Popular amenities for Simpsonville house rentals

When is the best time to visit Simpsonville?

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Quick stats about house rentals in Simpsonville

  • Total vacation rentals

    Explore 70 vacation rentals in Simpsonville

  • Nightly prices starting at

    Simpsonville vacation rentals start at $41 CAD per night before taxes and fees

  • Verified guest reviews

    Over 2,180 verified reviews to help you choose

  • Family-friendly vacation rentals

    40 properties offer extra space and kid-friendly amenities

  • Pet-friendly vacation rentals

    Find 20 rentals that welcome pets

  • Rentals with dedicated workspaces

    40 properties have a dedicated workspace

  • Wifi availability

    70 of Simpsonville vacation rentals include wifi access

  • Popular amenities for guests

    Guests love Kitchen, Wifi, and Pool across Simpsonville rentals

  • 4.8 Average rating

    Simpsonville stays are highly rated by guests—averaging 4.8 out of 5!