House vacation rentals in South Carolina

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Top-rated house rentals in South Carolina

Guests agree: these houses are highly rated for location, cleanliness, and more.

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Guest favourite

Home in Saint Helena Island

4.98 out of 5 average rating, 117 reviews

The Tidewatch: Beachfront Retreat on Harbor Island

Enjoy the ultimate beach vacation at the Tidewatch! Located directly on the sand with spectacular ocean views. Relax on the home's wrap-around porches while spotting dolphins or take a dip in the ocean right outside your front door. Located within the private, gated community of Harbor Island, a barrier island near Beaufort, SC with easy access to Charleston, Savannah, and Hilton Head. Guests have access to Harbor Islands' miles of sandy beaches, resort style pools, and recreation facilities.

Guest favourite

Home in Westminster

4.94 out of 5 average rating, 265 reviews

Waterfall Views, Lake Hartwell, Highland Architect

Come and enjoy nature with 100+ acres to roam. Paths for long walks. Architect James Fox designed this cliffside home overlooking a beautiful waterfall. Feel like you are in the trees, in an area much as it was when inhabited by Cherokee Indians. Stream feeds into Lake Hartwell. In the summer months on the weekends and holidays kayaks, jet skis and small boats visit the falls. This property is in the foothills of the Appalachian Mountains. Please respect our pet policy, only service animals.

Guest favourite

Home in Chappells

4.95 out of 5 average rating, 151 reviews

Greenwood Lake Front, FirePit, Outside Kitch, Dock

Our place is unlike any other on the lake! The home is fully stocked and includes kayaks, pedal boat and lilly pad for your enjoyment. We have a dock and firepit. You will have no need to go anywhere else while you are here, as Camp Q has so many things to offer. The outside kitchen has 2 grills and a fridge. You’ll love my place because of the outdoors space, and the ambiance. My place is good for couples, solo adventurers, families (with kids), big groups, and furry friends (pets).

Guest favourite

Home in Charleston

4.99 out of 5 average rating, 112 reviews

Waterfront Home Near Downtown!

Roomy waterfront home near Downtown Charleston! This 2 bedroom 1 bath home is perfect for family vacations or trips with friends. This stylish house is less than 5 minutes from Downtown Charleston and 15 minutes from Beautiful Folly Beach. Bring your paddle board or kayak and launch right from the back yard. This property is located right on Lake Francis and right outside you will see egrets, herons, ibis, and tons of other amazing birdlife. You will love your new home away from home!

Guest favourite

Home in Georgetown

4.91 out of 5 average rating, 116 reviews

Maggie Jo’s paradise on the river !

Reconnect with nature at this unforgettable escape. Maggie jo is a 1970 completely restore houseboat. She has got a full size refrigerator , gas range ,microwave and toaster oven. Out on the back deck she has a gas grill. The aft berth has 2 full beds that are extremely comfortable. Galley dinette make into bed and the couch in the saloon pulls out also. While on the decks you will see eagles, dolphins , gator or fishing jumping out of the water. I also have 2 tandem kayaks for your use.

Guest favourite

Home in Greenwood

5 out of 5 average rating, 100 reviews

The Little White House

Kick back and relax in our BRAND NEW guest house. We have put a lot of thought and effort into our space for you to have a comfortable stay. Enjoy a country living feel while being just minutes from shopping, restaurants, and the hospital. The host also live behind the property should you need anything. No pets. No smoking. This space is for paying guest only. No parties! We also have a 2nd listing in Greenwood- The Cottage @ Hill & Dale. *OWNER IS A LICENSED REAL ESTATE AGENT.

Guest favourite

Home in Easley

4.91 out of 5 average rating, 295 reviews

“Lake House Paradise” Waterfront Oasis

“Lake Paradise” is exquisitely furnished with 2 bedrooms and 1 and a half baths. Your Master Suite has its own screened in porch with private lake access. Wake up from your master suite to views from your bed of the water. Your en suite Master Bathroom has a large luxury marble shower. You will spend many hours of relaxation and peace in the most desirable location in the southeast. Visit Greenville SC's downtown just 15 minutes away. Clemson football Stadium is 20 miles away.

Guest favourite

Home in Greenville

4.99 out of 5 average rating, 159 reviews

Cozy Treehouse

Situated at the back of a wooded 2 acre lot, only 10 minutes from downtown Greenville, this is a little oasis in the city! While most treehouses take you on a "roughing it" adventure, Cozy Treehouse is the glamping version of treehouses, boasting 9' ceilings, 1.5 baths, 3 LED TV's and many outdoor living options. If you are looking for a unique getaway just minutes from one of the top growing cities in the south, Cozy Treehouse is the perfect destination for you.

Guest favourite

Home in Prosperity

4.99 out of 5 average rating, 147 reviews

Anchors Aweigh

You'll enjoy this small cabin located less than 2 miles from Dreher Island State Recreation Area. The views from the living area and kitchen are breath-taking. You can sit on the dock & watch the sun set or take your boat out just a few hundred yards to watch the sun rise. This location is great for swimming & a dock is available so you can bring your boat. There is also great fishing from the dock and on a boat. This will provide an unforgettable vacation!

Guest favourite

Home in Surfside Beach

4.93 out of 5 average rating, 195 reviews

Nanny & Pops cozy beach cottage -3 blocks to beach

Great cozy beach house cottage in Surfside beach! A 2 minute walk to the ocean, pier, local restaurants, and bars. South of Myrtle Beach, and minutes from Murrell's Inlet. Nice Large Deck to sit outside and enjoy as well. Professionally decorated interior with top of the line linens. Private driveway, storage shed with beach chairs, nets, and grill included. Brand new outdoor shower! Please do not hesitate to let us know if you have questions at all.

Guest favourite

Home in Folly Beach

4.85 out of 5 average rating, 149 reviews

Luxury Beach Front Pet Friendly

Located minutes from the Morris Island Light House, indulge in the epitome of seaside luxury at our beachfront vacation home, where every detail has been thoughtfully curated to ensure a perfect retreat. Located directly on Folly Beach's pristine shores, this 2023 to the studs renovated cottage seamlessly blends opulence with comfort, offering a harmonious escape for you, your loved ones, and even your four-legged friends.

Guest favourite

Home in Summerton

4.97 out of 5 average rating, 132 reviews

Luxurious Lakefront Log Home W/Pool & hot tub

Gorgeous luxury log home directly on the big waters of Lake Marion with fishing pier/boat dock, brand new salt water pool, hot tub and much more! This custom home boasts 3 large bedrooms and a loft, two large bathrooms with double sinks, one with claw foot soaker tub and separate water closet. Huge screened in back porch for dining and entertainment with custom 12' outdoor bar. This home is 6 minutes from I-95.