Hotel vacation rentals in South San Francisco

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Top-rated hotels in South San Francisco

Guests agree: these hotels are highly rated for location, cleanliness, and more.

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Superhost
A well-lit room features a spacious bed with a patterned duvet cover. Two accent chairs and a small table are positioned beside a window with sheer curtains, allowing natural light to illuminate the space. A television and a vintage-style cabinet are also present.
Hotel room in Cathedral Hill
4.83 out of 5 average rating, 47 reviews

Broadmoor Studio 429

The Broadmoor - A family-owned business since the 1960s. Step back in time and enjoy staying at a traditional residence hotel. While once a retirement community, The Broadmoor now serves many types of residents and guests. Breakfast in our restaurant is included with each night's stay. Centrally located on Cathedral Hill near Japantown and Lower Pacific Heights, all of San Francisco is easily accessible. If in need of assistance, our 24-hour front desk concierge and security are available.

Superhost
A cozy bedroom features a spacious bed with decorative pillows and a soft blanket. Two bedside lamps provide gentle lighting beside wooden furniture. A large mirror reflects the room's details, while skylights above allow natural light to brighten the space.
Hotel room in Berkeley
4.94 out of 5 average rating, 145 reviews

Rock Roulade Cocoon

Your own space/ no shared rooms, easy access ground floor and convenient location. This unique place has a fresh style all its own. Formally a secret famous recording studio for pop-rock bands, it was known as “The Hearst”. World famous records by the Killers were made here, “Hot fuss” and “Sawdust”. The first room, (now bedroom) was the control room with recording equipment and the second room (now tub room) was where the musicians played. Welcome pets for a fee if $35/per pet -per night.

Superhost
A well-lit room features a spacious bed with gray linens. A small table and chairs are positioned next to a window. A flat-screen TV is mounted on the wall opposite the bed, with a white shelving unit nearby. The room offers a minimalist design.
Hotel room in South Beach
4.81 out of 5 average rating, 52 reviews

SoMa 9 Residences Room 7 Shared Bath

SOMA (short for South of Market St) is top of the list for where to stay in San Francisco for the first time. SOMA 9 Residences is located in the Heart of SF SOMA District, were you'll find everything from shopping to fine dining, plus landmarks such as Yerba Buena, Moscone convention center, SF MOMA, and steps away to Giants Ballpark. The proximity to Market St. makes SOMA one of the most accessible areas of the city. There's buses and rail lines (called BART) on just about every block.

Guest favourite
Hotel room in Yerba Buena
5 out of 5 average rating, 9 reviews

Sophisticated Stay | Cable Cars Tours. Gym

Located on Market Street, Hyatt Regency San Francisco Downtown SOMA is a sophisticated destination hotel close to the city’s most innovatively stimulating sights. Attractions are just nearby: ✔Picturesque picnics at Golden Gate Park ✔Contemporary and modern paintings, photographs, sculptures and designs from the 20th century, all housed at SF MOMA ✔Postcard-worthy shots, at Golden Gate Bridge ✔Beaux-Arts wonder, the Palace of Fine Arts ✔Best views of San Francisco at Twin Peaks

Top guest favourite
A cozy bedroom features a queen size bed adorned with a floral-patterned coverlet and decorative pillows. A colorful chandelier hangs above, while built-in shelves showcase books and decor. Natural light filters through sheer curtains, illuminating the warm, earthy tones of the room.
Casa particular in San Francisco
4.97 out of 5 average rating, 89 reviews

Elegant Noe Valley/Glen Park private suite

Elegant private suite in the Noe Valley/Glen Park neighborhood of San Francisco on a quiet, safe street convenient to transport (J Church Streetcar, 24 Muni bus, BART), restaurants and shopping. Private entrance, queen size bed, high fidelity entertainment system, private white marble bathroom w/ shower and soaking tub, private office with desk and printer; refrigerator, microwave and coffee maker. Free parking on quiet street. Ideal for couples who like to walk. Infants permitted.

Guest favourite
The spacious room features a comfortable bed against a backdrop of elegant decor. A vintage clock adorns the wall, while a plush sofa and glass coffee table create a welcoming seating area. A dark wood desk is positioned next to a flat-screen TV.
Hotel room in Nob Hill
4.9 out of 5 average rating, 63 reviews

San Francisco Suites Studio I on Nob Hill

Experience true hospitality in an Edwardian setting that is filled with European paintings,antique furniture,crystal chandeliers and a full service kitchen in every suite. You can also have your coffee upstairs in the gazebo overlooking the City. In the afternoon wine,cheese and crackers are served in the lobby and sherry is offered in the evening in front of the fireplace. The concierge will make your dinner reservations and when you depart, the cable car awaits on Powell Street.

Superhost
The exterior view of The Marker showcases its Beaux-Arts architecture with elegant detailing. Multiple stories feature large windows, illuminated at dusk, creating a welcoming ambiance. The building is framed by trees and streetlights, set against a softly lit sky.
Hotel room in Tenderloin
4.86 out of 5 average rating, 110 reviews

Union Square Stay | On Site Restaurant & Bar

Steps from San Francisco’s vibrant Union Square, The Marker blends over a century of hospitality with modern elegance. This boutique Beaux-Arts hotel offers curated amenities like PATH water bottles, FloWater stations, and a 24- hour state-of-the-art fitness center. Dine at Tratto, serving rustic Italian dishes and craft cocktails. With concierge service, curbside valet parking, and California Green Lodging certification, The Marker pairs timeless charm with contemporary comfort.

Superhost
A spacious bedroom features a king bed topped with decorative pillows. Two bedside lamps provide soft lighting. A small desk with a chair is situated near a window adorned with sheer curtains that filter natural light. Metallic wall art enhances the contemporary design.
Hotel room in Downtown / Union Square
4.85 out of 5 average rating, 55 reviews

Studio Suite in the cultural Epicenter of San Fran

Just one block from Union Square, this resort is ideally located to explore all the San Francisco sights. Just a short walk or iconic cable car ride away from popular attractions in the Bay Area & Michelin star eateries. Covid-19: Enhanced cleaning protocols in place. • Guest checking in must be 18+ with valid ID & card for $250 refundable security deposit (credit card only) • Name on reservation must match photo ID at check-in • Valet parking on-site for $57 + tax per night

Superhost
A spacious room is highlighted by a large bed with a white duvet and decorative pillows. A modern artwork featuring a woman and butterflies is mounted above the bed. Two bedside tables flank the bed, and a window with sheer curtains allows natural light to enter.
Hotel room in Downtown / Union Square
4.85 out of 5 average rating, 107 reviews

Book-filled Writer’s Alcove in the lobby

Channeling the spirit of the Beat Generation, every room at Hotel Emblem is a creative retreat featuring a writing desk with an inspiration board. Enjoy plush pillowtop beds with Italian linens, a 55" HD TV, and unique touches like a meditation bowl, typewriter, and coloring books. Thoughtful amenities include in-room coffee and tea, ROIL bath products, and high-speed internet. With pet-friendly options and hotel bikes, your San Francisco stay is both inspiring and comfortable.

Superhost
A room with two double beds is framed by wooden headboards, featuring crisp white linens. A nightstand with a lamp and a phone is positioned between the beds, enhancing the functionality of the space.
Hotel room in Millbrae
4.89 out of 5 average rating, 101 reviews

Bay Area Escape | Hotel Room. Free Breakfast

If you plan to explore the Bay Area, The Millwood Inn & Suites is a great jumping-off point. This quaint hotel is located in Millbrae, California, only minutes from Bay Area attractions such as the Golden Gate Bridge. It is also only a six-minute drive from San Francisco International Airport, perfect for those flying in! Be welcomed into a world of comfort and convenience after a long day of exploring California's best. ✔ Free breakfast ✔ Free parking ✔ Fitness center

Guest favourite
A comfortable living area features a gray sofa and a vibrant orange armchair. A small white table is positioned in front of the sofa. The space includes a flat-screen TV mounted on the wall and a cozy fireplace beneath a decorative mantel.
Hotel room in Glenmoor
5 out of 5 average rating, 9 reviews

Queen Studio w/ Kitchen & Free Breakfast

Enjoy the comforts of home at this Fremont hotel. Perfectly positioned near top shopping, dining, and entertainment, the hotel offers easy access to San Francisco, Oakland, and San Jose. Located near Lake Elizabeth, guests can explore Coyote Hills Park, Olive Hyde Art Gallery, Great America Theme Park, and premier golf courses like Sunol Valley and Pleasant Hills. Our welcoming and knowledgeable staff are dedicated to making your stay truly memorable.

Guest favourite
An outdoor pool area features a rectangular swimming pool surrounded by lounge chairs positioned on wooden decking. Palm trees provide shade, while several seating areas with tables and chairs are visible in the background, all set against a modern architectural backdrop.
Hotel room in Mountain View
4.9 out of 5 average rating, 870 reviews

King Bed at Shashi Hotel in Mountain View

Experience our King room type at Shashi Hotel Mountain View, an Urban Resort. Conveniently, located in the heart of the Silicon Valley - walking distance to Shoreline Amphitheatre. Taste incredible cocktails and delicious bites at our Emerald Hour Bar designed by our Michelin-rated Chef. Enjoy complimentary amenities including our outdoor pool, fitness center, sauna and steam rooms. New for 2025 - daily wine tasting, yoga, zumba, and live music.

Popular amenities for South San Francisco hotels

Quick stats about hotel rentals in South San Francisco

  • Total vacation rentals

    Explore 50 vacation rentals in South San Francisco

  • Nightly prices starting at

    South San Francisco vacation rentals start at $476 CAD per night before taxes and fees

  • Verified guest reviews

    Over 250 verified reviews to help you choose

  • Family-friendly vacation rentals

    20 properties offer extra space and kid-friendly amenities

  • Pet-friendly vacation rentals

    Find 40 rentals that welcome pets

  • Vacation rentals with a pool

    20 properties feature pools

  • Rentals with dedicated workspaces

    50 properties have a dedicated workspace

  • Wifi availability

    50 of South San Francisco vacation rentals include wifi access

  • Popular amenities for guests

    Guests love Kitchen, Wifi, and Pool across South San Francisco rentals

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