Vacation rentals with a washer and dryer in Cape Girardeau

A view from the front porch showcases a vibrant autumn scene, with trees covered in golden leaves. A cozy seating area is visible, framed by white railings, and a peaceful street with fallen leaves creates a calm atmosphere.

4.98 out of 5 average rating, 432 reviews

Beautiful Historic Boulevard District Apartment

This beautiful, private upstairs apartment is located on a favorite street in Cape Girardeau’s Historic Boulevard District. It is walking distance to SEMO University, Capaha Park, and the downtown riverfront. Recently remodeled for laundry, spacious rooms offer private bedroom spaces and a cozy den for watching movies or reading. The kitchen is fully equipped with amenities. This quiet neighborhood setting even has a front porch swing and sitting area where you can enjoy your morning coffee.

4.99 out of 5 average rating, 106 reviews

Treehouse in Perryville

TreeRise - Unearth Your Calm

Break free from the grasp of our hurried culture and reconnect to a place within at the unforgettable TreeRise. Where the elevated views will inspire you while the comforts of luxury will provide respite and enlightenment to your spirit. We created the TreeRise with an inspired state of mind, and we are hopeful that same inspiration will be experienced and reflected during your stay. Go to sleep counting stars + wake up with the trees! We can't wait to provide you with the TreeRise experience!

The cottage exterior presents a single-story structure with light blue siding and a dark roof. A wooden deck is located at the front, featuring a railing. The yard is grassy, bordered by a privacy fence, with a driveway visible beside the house.

4.84 out of 5 average rating, 127 reviews

Herman's Corner Cottage.

Tucked in historic Cape Girardeau, this charming cottage offers comfort and convenience. Enjoy the cozy back deck with a privacy fence—perfect for relaxing or grilling. With ample off-street parking, your stay is stress-free. The home is equipped with essentials for a smooth, hassle-free visit. Book the entire house for added privacy, providing a peaceful retreat for you and your guests. Experience the perfect blend of comfort, affordability, and convenience during your Cape Girardeau getaway.

A spacious living area features large windows allowing natural light to fill the space. A comfortable grey sofa is paired with a unique coffee table, while stylish dining chairs surround a white table. The kitchen area includes modern appliances and cabinetry.

4.95 out of 5 average rating, 270 reviews

Brand new 2 bedroom unit right in downtown Cape.

This special place is close to everything, making it easy to plan your visit. Walking distance to restaurants, the river and nightlife. Property includes wifi, full kitchen, laundry, deck and private parking for one. One king bed room and a twin bed room in addition to a roll out twin bed along with a 60 inch smart television. Dog bed and bowls included along with board games! Property is conveniently located across the street from "The Bar" the famous spot from the movie "Gone Girl" .

4.93 out of 5 average rating, 110 reviews

The kitchen area features a central island with two sleek stools, complemented by a modern black vent hood. Stainless steel appliances, including a refrigerator and stove, are positioned against a marble countertop. Decorative plants and tableware enhance the stylish design of the space.

Loft in Cape Girardeau

Riverwalk Loft 1

If you are looking for something right in the middle of the excitement, book now! This is your place. Our lofts are right in the heart of Downtown. In walking distance to breweries, casinos, and shopping galore.Our building is directly in front of the Mississippi River entrance. Walk around the corner either to get an ice cream for a late night snack. Beds are super comfortable but downtown isn’t the quiet part of town. The train runs periodically. You will have the typical night life noise.

5 out of 5 average rating, 123 reviews

A modern dome structure features large glass panels creating a bright and inviting environment. Surrounded by lush greenery, the architecture harmonizes with nature. A wooden deck with seating is visible in front, offering a space for relaxation and outdoor enjoyment.

Dome in Cobden

The Dome At Blueberry Hill

Escape to The Dome at Blueberry Hill, where comfort meets nature for a truly unforgettable glamping experience. Set on two private acres along the scenic Shawnee Hills Wine Trail and minutes from the charming village of Cobden- you’ll enjoy peaceful seclusion with easy access to local charm. The fully insulated dome offers cozy, climate-controlled comfort year-round. Sip wine under the stars or unwind in style indoors. Make lasting memories at The Dome- your luxury glamping retreat awaits.

The exterior of a charming brick farmhouse is displayed, featuring a symmetrical layout with two dormer windows. A well-maintained lawn surrounds the house, complemented by flower beds. A walkway leads to the welcoming entryway, which opens to a sunroom on the right.

4.97 out of 5 average rating, 148 reviews

River Run

Charming 1940s farmhouse. Updated 1 1/2 story house in a rural setting overlooking the Mighty Mississippi River, but close to the heart of Cape Girardeau. Our house has lots of room to relax with a large kitchen and sunroom. You can sit by a cozy fire pit and enjoy chilly evenings watching the beautiful sunsets. We look forward to you spending time in our neck of the woods (so to speak). We are located with in seven miles from the Isle casino, SEMO state university and a happening down town.

The building features classic brick architecture with ornate ironwork detailing on the balcony. A large clock is positioned on the exterior wall. Nearby streets and parked vehicles are visible, along with a clear blue sky providing a bright backdrop.

4.98 out of 5 average rating, 102 reviews

Historical Kage House

The Building is reminiscent of eighteenth-century New Orleans architecture, and was built sometime before 1883. The Kage House is located at 120 Broadway in the historical district and is less than a minutes walk to Main Street and less than a 10 minutes walk to the Isle of Capri Casino. On Main Street you will find many fine shops and restaurants, or just enjoy the scenic area as you walkabout. This is by far one of the best places in Cape. Additional reviews can be read on the VRBO website.

A spacious living room is furnished with a large sectional couch, complemented by decorative pillows. A wooden coffee table sits center stage on an area rug. A ceiling fan is visible, and light enters through window treatments, creating a comfortable atmosphere.

4.84 out of 5 average rating, 137 reviews

5 Bed Home in Great Neighborhood - Sleeps 10

Looking for a comfortable and spacious Airbnb in Cape Girardeau? 🏡✨ This 3 bedroom, 2 bathroom home in a great neighborhood is the perfect spot for your next group stay. This home features great living areas to relax and unwind including a living room with a large sectional and 70 inch TV. The game room features an air hockey table, dart board, and other board games. It will sleep 10 comfortably. Make this your destination for your next girls trip, sports tournament, or SEMO event.

Cottage in Cape Girardeau

A charming brick house is presented, featuring a front porch supported by columns. Large windows allow natural light to brighten the interior. The lush green lawn is bordered by a stone pathway leading up to the entrance, surrounded by well-manicured shrubs and trees.

4.98 out of 5 average rating, 370 reviews

The Candle Cottage in downtown Cape.

All the best that downtown Cape Girardeau has to offer just steps away from your front door! Short distance from Isle Casino and just 2 1/2 blocks from the Mississippi River walk, downtown restaurants, shops and minutes from Southeast Missouri State River Campus. Completely renovated with loads of charm and coziness, high ceilings, comfy bed, fully stocked kitchen, and laundry. My place is ideal for couples, solo adventurers, and business travelers. Owner is licensed real estate agent.

4.94 out of 5 average rating, 228 reviews

A modern farmhouse is depicted at sunset, featuring a welcoming entrance with a covered porch. A stone pathway leads to the front door, bordered by a grassy lawn that extends to fields and trees in the background.

Barn in Cape Girardeau

Under the Stars - Farmhouse

Enjoy the tranquility of this modern farmhouse charmer! Custom built minutes from downtown Cape. Relax outside around the fire pit, roast marshmallows and watch the sunset. Finish the night with a long soak in the hot tub. Start the morning on the front porch rocking chairs and take in a sunrise. Open concept, fully equipped kitchen, 3 Bd. including King master/full bath, 2 Queens with full guest bath. Near Trail of Tears and walking distance to classic dive bar/burger joint

4.97 out of 5 average rating, 173 reviews

Cabin in Carbondale

Romantic Cabin w/ Hot Tub Near Carbondale

The Couple’s Retreat – Secluded Romantic Cabin Near Carbondale, Illinois Designed exclusively for one couple, The Couple’s Retreat is a peaceful hideaway where you can relax, reconnect, and rejuvenate. Enjoy a private hot tub surrounded by trees on a screened porch, cozy evenings by the fireplace, and wildlife views of deer grazing near the firepit. This restful cabin includes a grill, modern amenities, and all the comforts needed for a soothing, intimate Southern Illinois escape.

Popular amenities for Cape Girardeau washer and dryer rentals

Kitchen

Wifi

Pool

Free parking on premises

Air conditioning

Apartment rentals with a washer and dryer

Private Nurse Retreat 2 + Walk to SEMO Activities!

4.83 out of 5 average rating, 6 reviews

The living room features a comfortable sofa, an accent chair, and a wooden coffee table. A large TV is mounted on the wall, showcasing various streaming options. Natural light fills the space through windows, and a soothing piece of artwork is displayed.

Apartment in Jackson

Cozy & Comfortable 1 Bedroom Suite

A spacious living area features dark hardwood floors and light gray walls, accented by a comfortable leather sofa and an elegant coffee table. Artwork adorns the walls, and natural light streams in from the nearby windows, illuminating the inviting space.

4.92 out of 5 average rating, 49 reviews

Downtown 4BR with 2 King Beds! Off-street parking

4.83 out of 5 average rating, 29 reviews

Modern 2BR Apt w Electric Fireplace · By KeenStays

A private balcony offers outdoor seating with several chairs and a table. A clear view of the Mighty Mississippi River can be seen in the background, adding a scenic backdrop to the space. The balcony features a neutral-colored floor and walls.

4.84 out of 5 average rating, 38 reviews

The Outlook - Private Balcony

A comfortable living area features a light gray sofa and a dark recliner, arranged around a black coffee table. A patterned area rug adds warmth to the wooden floor. Framed artwork is displayed on the wall, complemented by soft lighting from ceiling fixtures.

4.8 out of 5 average rating, 5 reviews

Downtown Retreat

4.96 out of 5 average rating, 52 reviews

A cozy living area is furnished with two spacious brown reclining sofas, positioned around a soft area rug. A side table is visible, with a small decorative item placed on it. Natural light enters through a window covered by white blinds.

Apartment in Marble Hill

Lovely 2 bedroom apartment with luxury shower.

4.88 out of 5 average rating, 26 reviews

The exterior of a two-story home is shown, featuring a combination of brick and siding. A covered porch is located at the front, and large windows are visible. Lush green grass surrounds the house, with trees providing shade and a peaceful atmosphere.

Apartment in Oak Ridge

The Teal Door

House rentals with a washer and dryer

4.99 out of 5 average rating, 141 reviews

An outdoor seating area features a round table surrounded by four chairs, set on a stone patio. Flowering plants line the edge of a grassy space, and a door leads into the house. The clear blue sky and greenery provide a serene backdrop.

Home in Alto Pass

The Farmhouse in Rhine Valley

4.96 out of 5 average rating, 56 reviews

A charming cottage is framed by tall trees, with a paved walkway leading to the front door. The yellow exterior of the home contrasts with the greenery. Fallen leaves scatter across the grass, creating a serene and inviting visual.

Home in Anna

150 year old charmer!

4.96 out of 5 average rating, 91 reviews

A serene winter landscape is captured at dawn, showcasing trees adorned with shimmering ice. A wooden railing segments the view, emphasizing the vibrant orange and purple hues of the rising sun against a clear sky. Snow blankets the ground, enhancing the tranquil atmosphere.

Home in Cobden

4 mins to Bourbon Bar, wine trail, hot tub, views

4.5 out of 5 average rating, 8 reviews

Happy home for traveling professionals

4.95 out of 5 average rating, 251 reviews

The exterior of a charming A-frame home is surrounded by lush greenery and colorful blooming flowers. A well-maintained pathway leads to the front porch, where a family-friendly atmosphere is suggested by the welcoming design. Two windows are visible on the upper floor.

Home in Carbondale

Cozy 2 Bedroom Garden Oasis Home

4.84 out of 5 average rating, 177 reviews

A ranch-style home is set in a rural setting, featuring a brick exterior and a two-car garage. A curved gravel driveway leads to the entrance, surrounded by a large lawn and mature trees, providing a serene environment.

Home in Makanda

Ranch style home in country setting, near SIU-C

The exterior of a charming brick house is presented, surrounded by manicured green grass and shrubs. Large windows invite natural light, while the roof features a small chimney. A clear blue sky and scattered clouds create a pleasant backdrop to the home.

4.96 out of 5 average rating, 27 reviews

Located near downtown and casino

A vibrant living area features a mix of colorful seating options, including a pink armchair and a blue sofa. A stylish area rug with abstract patterns adds visual interest. A dining space can be seen in the background, inviting gatherings and shared moments.

4.96 out of 5 average rating, 54 reviews

Boho Chic

Other vacation rentals with a washer and dryer

4.97 out of 5 average rating, 62 reviews

An open living space features a kitchen area with modern appliances and a dining table surrounded by chairs. Pendant lights hang from the ceiling, illuminating a cozy seating area with plush sofas. A rustic wooden table is placed against the wall, enhancing the room's charm.

Cabin in Jackson

The Cabin at Timber Creek

4.96 out of 5 average rating, 53 reviews

A charming cabin is set amidst lush greenery, illuminated by soft outdoor lights along the gravel pathway. The exterior features light-colored siding and a sloping roof, with two windows glowing warmly in the evening light. Surrounded by natural landscaping, the cabin offers a serene retreat.

Cabin in Carbondale

Charmful Cabin next to refuge

5 out of 5 average rating, 33 reviews

A historical storefront in Makanda, Illinois, features rustic architecture with large windows and a distinct sign. The landscape is framed by trees and distant hills, while a lunar design adorns the sky above. The name 'Makanda, IL' is prominently displayed at the bottom.

Guest suite in Makanda

Vulture's Roost at the Iconic Makanda Boardwalk

5 out of 5 average rating, 36 reviews

A living room features wooden accent walls and large windows that frame views of the surrounding woods. Comfortable reclining chairs are positioned with a soft throw blanket draped over one. A small table with a lamp adds warmth, inviting relaxation. Natural light fills the space.

Cabin in Dongola

Edgewood Retreat

4.83 out of 5 average rating, 35 reviews

The rustic barn-style house is set against a backdrop of lush greenery, surrounded by trees and open fields. A winding gravel driveway leads to the entrance, providing access to the serene countryside setting.

Home in Advance

Willow Acres- 2BD/2BA w/ BBQ and outdoor patio

4.85 out of 5 average rating, 89 reviews

The kitchen features modern stainless steel appliances, including a large refrigerator, an oven, and a microwave. White cabinetry provides ample storage, while a counter area is equipped with cooking utensils and a coffee maker. A small rug adds comfort underfoot.

Loft in Perryville

A Cut Above Studio (1200 sq ft)

4.99 out of 5 average rating, 72 reviews

A spacious swim spa is featured, showcasing clear turquoise water with gentle jets creating soft splashes. The surrounding area is sunny, with a partial view of a gray building structure in the background. The setting evokes a sense of relaxation and tranquility.

Home in Perryville

Retreat Air *HOT TUB, King Bed, NO cleaning fee*

A charming two-story cottage features a red exterior with stone accents. The covered front porch is furnished with several chairs, providing a welcoming space. Large windows allow natural light to fill the interior, while a path leads to the entrance, framed by well-kept grass and plants.