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Pet-friendly vacation rentals in Cape Girardeau

Find and book unique pet-friendly homes on Airbnb

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Popular amenities for Cape Girardeau pet-friendly home rentals

Pet-friendly house rentals

Guest favourite
Home in Murphysboro
5 out of 5 average rating, 28 reviews

Sleeps 16! 7 Bedrooms! 8 Bathrooms! 8 Beds!

KevinRating, 5 stars4 months ago
Wonderful house and location to SIU. Weather didn't cooperate, but served its purpose!! Thank you for the hospitality and the amazing weekend that was very comfortable for our family of 10! I highly recommend this place, especially for large groups and SIU events!!
Superhost
Home in Murphysboro
4.88 out of 5 average rating, 72 reviews

Hilltop Retreat 2: Spacious, pondfront home for 12

SaigeRating, 5 stars5 months ago
In town for a hunting trip with a group of friends, house was perfect for the occasion. Will be back!
Guest favourite
Home in Makanda
4.88 out of 5 average rating, 56 reviews

Cedar Lake Retreat

LoganRating, 5 stars5 days ago
This is a beautiful area of southern Illinois. It’s a quick drive to murphysboro and Makanda and Carbondale. Also wineries are scattered throughout the area. Also a nice little private patio, grill and fire pit. Two bedrooms, nice kitchen and one bathroom. Will definitely stay here again.
Guest favourite
Home in Carbondale
5 out of 5 average rating, 14 reviews

Owls Nest

GustaboRating, 5 stars1 month ago
The Owls Nest was a perfect place to stay with our family and our 2 dogs. The fenced in back yard had plenty of room, a fire pit and nice sized deck. The bedrooms were all cozy and had comfortable beds. The living room has plenty of room to play games or watch a movie and the kitchen has everything you need . We love to hike and Mt Bike and this location was close to many hiking trails and about a 5 min drive to Touch of Nature trails for riding. We would definitely book another stay at the Owls Nest!
Guest favourite
Home in Cape Girardeau
4.96 out of 5 average rating, 23 reviews

Located near downtown and casino

DavidRating, 5 stars1 week ago
We had a great stay at your home! It was very nice and clean. We had everything we needed and it went very smooth.
Guest favourite
Home in Cape Girardeau
4.94 out of 5 average rating, 17 reviews

Clean home great Neighborhood - central location

FeliciaRating, 5 stars1 month ago
Great home, nice location, & safe area. Owner is very responsive and great communication. Would recommend for a person or a business stay.
Guest favourite
Home in Pomona
4.85 out of 5 average rating, 13 reviews

Shawnee Forest Vacation Lodge

DestinyRating, 5 stars1 week ago
This is a half way point for my grandma and I to meet up with my cousin. The place was amazing. Beautiful surroundings, pet friendly, and perfectly secluded for a peaceful getaway. Kevin was a great host and very responsive.
Superhost
Home in Cape Girardeau
4.8 out of 5 average rating, 10 reviews

Cottage Near Casino

KristinRating, 5 stars5 months ago
This was my 2nd extended stay at this home. Host is very responsive. It is a quick walk to the Riverwalk or the casino if you want. I stayed with my dog and appreciated the fenced in yard.

Pet-friendly home rentals with a pool

Top guest favourite
Camper/RV in De Soto
4.97 out of 5 average rating, 32 reviews

Glamping W/Hotub, pool, & lake

BrittanyRating, 5 stars1 month ago
The perfect place for a peaceful weekend getaway! I really enjoyed walking through the woods, playing fetch with their sweet pup, and soaking in the hot tub after hiking in the nearby Shawnee National Forest. Kevin was super helpful and responsive. I would love to come back sometime!
Home in Carbondale
4.52 out of 5 average rating, 82 reviews

Peaceful Custom Carbondale Home w/ Pool, Near SIU!

HilaryRating, 5 stars5 months ago
Loved staying at this location. So close to restaurants and shops and outdoor adventures. Very quiet. Amazing views of stars. Plenty of sleeping spaces. Very responsive and helpful host!
Top guest favourite
Camper/RV in De Soto
4.96 out of 5 average rating, 24 reviews

Camp in quiet w/ Spa Lake Pool

MegRating, 5 stars1 week ago
What wonderful, peaceful retreat! We were looking for somewhere to unplug and we found it! I honestly can't wait to go back.
Guest favourite
Camper/RV in De Soto
5 out of 5 average rating, 16 reviews

Wooded, Private Lake, Pool & Spa

LindseyRating, 5 stars6 months ago
Kevin's property was perfect. He and his family were very responsive and helpful when we needed some assistance with the RV. We came in late our first night but with Kevin's instructions had no problem finding the spot. the location is very peaceful. We wanted to do some hikes and see fall foliage and Kevin's place was a perfect base camp. We will definitely be back. I'm already shopping the idea with a few other families to find a weekend when we can rent all 3 RVs!

Private, pet-friendly home rentals

Home in Murphysboro
4.7 out of 5 average rating, 158 reviews

2 Bedroom country craftsman

BarbRating, 5 stars1 month ago
This was a great spot for us! We were not at the house but to sleep and it met our needs perfectly. Michael has taken on a restoration of this beautiful home and done a fabulous job!
Guest favourite
Cabin in Alto Pass
4.91 out of 5 average rating, 150 reviews

Hutchins Creek Cabin -2br- Wine Trail & Wilderness

AliceRating, 5 stars2 weeks ago
We enjoyed the beautiful wide porch with lots of bird sitings and the small lake with lots of turtles sunning themselves. Very peaceful!
Top guest favourite
Cabin in Alto Pass
5 out of 5 average rating, 24 reviews

Gram's Cabin at Bald Knob

CamilaRating, 5 stars5 days ago
Home was exactly as as described. We loved sitting on the front porch, enjoying a cup of coffee in the morning. Definitely will stay here again.
Superhost
Cabin in Marble Hill
4.64 out of 5 average rating, 25 reviews

Private Getaway on 270 Acres w/ Lake: Swim & Canoe

PollyRating, 5 stars4 months ago
AWESOME people and place, some of the amenities weren’t ready to use but as far as the cabin that you stay in and the owners were incredible! Great location if you’re doing anything in Advance. They went the extra mile to accommodate traveling duck hunters. Will definitely stay again when I’m in Advance!
Superhost
Apartment in Scott City
4.95 out of 5 average rating, 42 reviews

RiverSide Barn Suite on the Mississippi River.

LaraRating, 5 stars1 month ago
Great place to stay and within walking distance to great restaurant. Deb was amazing to work with and very responsive. Beds were comfortable and we had a great time. We will definitely stay here again.
Home in Cape Girardeau
4.57 out of 5 average rating, 53 reviews

Sweet home Walking distance to Mercy

MichealRating, 5 stars7 months ago
Mrs. Luci was so wonderful and very helpful! Always responsive and really took care of us! Will recommend and will stay again!
Townhouse in Murphysboro
4.83 out of 5 average rating, 48 reviews

Big Cozy 2 Bedroom Condo w/ Large Driveway

JohnRating, 5 stars2 weeks ago
Was a Great Place to stay! We were in the area for a funeral. Catherine was a great Host and very helpful! We were very thankful for being allowed to add 3 guests for 1 night which was my Brother, his Wife, and their 1 yr old Daughter. We weren't expecting the $59 up charge but could understand. We could have given a 5* on Clean, considering that it is a pet friendly place. Would have offered to fix the Laundry / bathroom door if I would've had the time and tools. We can definitely recommend the Place, and Catherine as a Host. Thank You Catherine for giving us a nice place to stay. God Bless You For That! We would consider this place again if we were in the area.

Quick stats about vacation rentals that are pet-friendly in Cape Girardeau

  • Total rentals

    40 properties

  • Nightly prices starting at

    $55 CAD before taxes and fees

  • Total number of reviews

    3.3K reviews

  • Family-friendly rentals

    20 properties are a good fit for families

  • Rentals with dedicated workspaces

    30 properties have a dedicated workspace

  • Wifi availability

    40 properties include access to wifi

Destinations to explore