House vacation rentals in Des Moines

Find and book unique houses on Airbnb

Top-rated house rentals in Des Moines

Guests agree: these houses are highly rated for location, cleanliness, and more.

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Guest favourite

Home in Des Moines

4.95 out of 5 average rating, 177 reviews

Cozy Historic Escape

This comfortable bungalow is stylish with historic charm. The front porch is perfect for morning coffee. The main living space has original hardwood floors and classic brick fireplace with craftsman style built-ins. The house also has fenced in backyard with patio for enjoying temperate days. It is centrally and conveniently located close to Des Moines Playhouse, ~6 minutes from Wells Fargo Arena and Downtown Des Moines, ~13 minutes to Jordan Creek Town Center, and ~15 minutes to DSM Airport.

Dec. 12 – 19

$230 CAD per night

Guest favourite

Home in Des Moines

4.99 out of 5 average rating, 160 reviews

Gateway House

Our 100% SMOKE-FREE Gateway House is nestled just west of beautiful Downtown Des Moines. I-235 is 90 seconds away, putting you downtown in 5 minutes, and anywhere else in 15 minutes! Ingersoll Avenue, home to dozens of locally owned restaurants and bars, is a 2–3-minute drive and a 5-10-minute walk. Our charming bungalow has everything you need to function! We proudly display artwork that accents the culture our city has to offer, and you will feel relaxed indoors and out during your stay.

Oct. 3 – 10

$179 CAD per night

Guest favourite

Home in Des Moines

4.9 out of 5 average rating, 199 reviews

Cozy, Quiet & Spacious Home Minutes from Downtown

You will be close to everything when you stay at this centrally-located home, which is right off I-235 and less than 5 minutes from downtown Des Moines and the Drake neighborhood, 10 minutes to the Fair Grounds, and about 40 minutes to Ames for those traveling north. This home offers one king, one queen, and a queen pull-out along with a very large living & dining area, a coffee station, a fully-stocked beverage fridge, a private outdoor patio, and is in a very quiet, peaceful neighborhood.

Nov. 14 – 21

$197 CAD per night

Guest favourite

Home in Winterset

4.97 out of 5 average rating, 195 reviews

The Legacy Stone House

The most unique stay in Winterset! Legacy Stone House AirBnB is a historic residence located one mile east of Winterset, Iowa. Built in 1856 during the Settlement Era of Madison County, it is one of nearly 100 stone houses built during that time in the area. Officially named the William Anzi Nichols House, it is listed on the National Register of Historic Places. Convenient centralized location if visiting Madison County’s six covered bridges and two minutes from grocery, gas and dining.

Mar. 21 – 26

$256 CAD per night

Guest favourite

Home in Des Moines

4.91 out of 5 average rating, 132 reviews

Cheerful 2 bedroom, 3 bed home near Adventureland

You will able to enjoy everything when you stay at this centrally-located small (700 square feet) cottage. A 7 min drive to Adventureland, 11 min drive to the Iowa State Fair Grounds, and 13 min drive to the Iowa Events Center will keep you on your feet with events! Enjoy the entire newly redone 2 bedroom house with free parking, enhanced cleaning, self check in/out, full kitchen with Keurig coffee maker, full washer/dryer, full bathroom, Smart TV, AC/heat, and quality safety features.

May 29 – Jun. 5

$144 CAD per night

Guest favourite

Home in Des Moines

4.99 out of 5 average rating, 140 reviews

Peaceful Setting & Modern Style

Escape the hustle and bustle of the city and retreat to your own private oasis with this charming 2 Bedroom Airbnb. The house provides present-day amenities while still honoring the original 1930s character. You’ll enjoy a new and sparkling clean kitchen, complete with all the appliances and utensils you need. The bathroom, laundry, dining room, reading nook and living room have all been beautifully updated as well, ensuring that you'll feel right at home from the moment you arrive.

Sep. 23 – 30

$182 CAD per night

Guest favourite

Home in Windsor Heights

4.92 out of 5 average rating, 291 reviews

• Iconic Lustron home with 2 king beds •

This Lustron home is located in the peaceful neighborhood of Windsor Heights. This all steel ranch has 2 king beds, one bathroom with shower/tub, and a dining room open to the living room. The four seasons porch is surrounded by trees and over a thousand shade plants. Offering so much privacy you’ll forget you’re in the city! Conveniently located off the interstate near restaurants, grocery stores, shopping, and a 10 minute drive to downtown Des Moines. Complimentary Hulu provided.

Mar. 31 – Apr. 7

$245 CAD per night

Superhost

Home in Des Moines

4.84 out of 5 average rating, 244 reviews

Cozy Spa Home Close to Downtown

Enjoy the feeling of a cozy home while you visit Des Moines! This wonderful home is close to downtown, bike trails, and Riverview park where you can walk the Des Moines river. Lots of light, beautiful fenced backyard with porch, fire pit, and large charcoal grill! Full kitchen with Everything you need to cook an amazing meal. Bathroom with a large double head shower, and large soaking tub. Hulu, Netflix, and Amazon are set up on three televisions. Washer and dryer for your use!

Guest favourite

Home in Ankeny

4.94 out of 5 average rating, 117 reviews

Newly Remodeled Home with Walk-In Shower

My home is located in a safe and quiet neighborhood of Ankeny with a 16 min. drive to downtown Des Moines and Wells Fargo Arena. The high trestle trail is about 8 blocks away with a nice park 1 block away. The highlight of my home is the newly remodeled bedrooms and bathroom. There are queen beds in each of the bedrooms. The living room has a 55” LG OLED 4k TV with a PlayStation 4. I have high-speed cable internet/TV with standard and slingTV cable channels.

Jul. 8 – 13

$143 CAD per night

Guest favourite

Home in Des Moines

4.95 out of 5 average rating, 324 reviews

Quiet Hideaway Retreat/1 King/2 Queen beds

Lower level suite, 1 bedroom with a king size bed and the 2nd bedroom has a queen bed. Queen sofa sleeper couch in the living room. The four season porch walks out to a patio with firepit and gas grill. Walking distance to Waveland Golf Course & Tennis Courts, Neighborhood Diner Waveland Cafe and La Mie Bakery. Minutes away from Ingersoll Avenue, downtown Des Moines, and Court Avenue. 20 minutes from Adventureland amusement park and Prairie Meadows Casino.

Nov. 3 – 10

$202 CAD per night

Guest favourite

Home in Des Moines

4.94 out of 5 average rating, 105 reviews

The Metal House

Discover a rare piece of history right in the heart of Beaverdale, Des Moines. This modular home is entirely built from steel, and continues to shine over 70 years later. It's been tastefully filled with todays amenities including an updated kitchen, bathroom, laundry, Wifi and color TV! Have fun in the bonus game room with ping pong and and arcade version of Ms Pac-man! Take a stroll to downtown Beaverdale, where you'll find bars, shops and restaurants.

Jul. 15 – 22

$233 CAD per night

Guest favourite

Home in Des Moines

4.79 out of 5 average rating, 184 reviews

Charming home minutes from Downtown Des Moines

Whether for business or for fun you will love this home! In a quiet, safe neighborhood this home is located just minutes from Downtown Des Moines and close to the airport. Entertainment and food is just minutes away even within walking distance. This newly remodeled home is the perfect cozy stay. With something always to do in the area. Des Moines is the perfect place to visit!

Aug. 21 – 28

$161 CAD per night