House vacation rentals in Florence
Find and book unique houses on Airbnb
Top-rated house rentals in Florence
Guests agree: these houses are highly rated for location, cleanliness, and more.
Vacation rentals for every style
Get the amount of space that is right for you.
Popular amenities for Florence house rentals
House rentals with a pool
Home in Myrtle Beach
4.9 out of 5 average rating, 354 reviewsBeach Style Cottage One Block To Beach!
Nov. 28 – Dec. 5
Home in Columbia
4.9 out of 5 average rating, 126 reviewsSouthern Comfort 4bed- saltwater pool- Ft. Jackson
Oct. 12 – 19
Home in Summerton
4.97 out of 5 average rating, 112 reviewsLuxurious Lakefront Log Home W/Pool & hot tub
Feb. 19 – 26
Home in Myrtle Beach
4.89 out of 5 average rating, 184 reviews“Mermaid’s Dream” Short Walk from the Waves & Pool
Feb. 5 – 12
Home in North Myrtle Beach
4.9 out of 5 average rating, 205 reviewsLuxury St. Kitts Villa in Caribbean Style Resort
Oct. 9 – 16
Home in North Myrtle Beach
4.99 out of 5 average rating, 101 reviewsLuxury Ocean View - Private Pool/Jacuzzi, Elevator
Nov. 16 – 23
Home in North Myrtle Beach
4.93 out of 5 average rating, 159 reviewsLuxury Villa in Caribbean-Style Beach Resort
Dec. 14 – 21
Home in Myrtle Beach
4.91 out of 5 average rating, 188 reviewsPrivate Beach Paradise in Ocean Lakes w/ Golf Cart
Jul. 20 – 27
Weekly house rentals
Home in Florence
5.0 out of 5 average rating, 42 reviewsRenovated 2 BR/2 B Townhouse Cozy & Clean
Sep. 30 – Oct. 7
Home in Florence
4.91 out of 5 average rating, 11 reviewsCan do condo!
Jul. 10 – 17
Home in Florence
4.92 out of 5 average rating, 89 reviews** Relax and Rest with Us in Florence **
Jul. 14 – 21
Home in Florence
4.96 out of 5 average rating, 51 reviewsPineapple House Historic Southern Charm Downtown
Sep. 2 – 9
Home in Florence
4.83 out of 5 average rating, 6 reviews2b/1.5bath brand NEW townhouse Closed to MUSC
Sep. 12 – 19
Home in Florence
4.87 out of 5 average rating, 30 reviewsTravelers mid-downtown home work truck parking
Jun. 22 – 29
Home in Latta
4.94 out of 5 average rating, 16 reviewsPrivate Country Escape
Jun. 9 – 16
Home in Florence
4.98 out of 5 average rating, 43 reviewsCozy home in Florence, SC
Apr. 20 – 27
Private house rentals
Home in Hartsville
4.97 out of 5 average rating, 88 reviewsCozy bungalow conveniently located
Nov. 16 – 23
Home in Sumter
4.98 out of 5 average rating, 63 reviewsThe Parkside Retreat
Feb. 28 – Mar. 7
Home in Dalzell
4.99 out of 5 average rating, 81 reviewsHome away from home
Jun. 16 – 23
Home in Bennettsville
4.97 out of 5 average rating, 33 reviewsHistoric Little House in Town
Jun. 4 – 11
Home in Florence
5.0 out of 5 average rating, 10 reviewsDOWNTOWN Boho & Vibrant Cottage on Park
Feb. 4 – 11
Home in Rockingham
5.0 out of 5 average rating, 19 reviewsLittle Yellow Cottage
Dec. 25 – Jan. 1
Home in Hartsville
5.0 out of 5 average rating, 42 reviewsManchester Place
Sep. 6 – 13
Home in Darlington
4.9 out of 5 average rating, 10 reviewsFarmhouse, 6 min from Nascar with great fishing!
Jul. 7 – 14
Quick stats about house rentals in Florence
Total rentals
60 properties
Rentals with dedicated workspaces
40 properties have a dedicated workspace
Pet-friendly rentals
10 properties allow pets
Family-friendly rentals
40 properties are a good fit for families
Total number of reviews
1.3K reviews
Nightly prices starting at
$14 CAD before taxes and fees
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