
House vacation rentals in Isle of Palms
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Top-rated house rentals in Isle of Palms
Guests agree: these houses are highly rated for location, cleanliness, and more.
Vacation rentals for every style
Get the amount of space that is right for you.
Popular amenities for Isle of Palms house rentals
House rentals with a pool

54 Grand Pavilion Wild Dunes, IOP, SC Beach Views

Private Entrance Suite w/ pool, 5 min from beach

SALTWATER OASIS AT THE BEACH, Isle of Palms, SC

Massive hot tub& porch, 3/2, center of Folly!

4 BR Beach House | Heated Pool | Pet Friendly

Escape to this Isle of Palms home w/ private pool

Lux Beach Bungalow Ocean Views Heated Pool

Pineapple Palms 337C Sea Cabin Isle of Palms SC
Weekly house rentals

Isle of Palms Family Beach House

Little Boho Beach House ( Oceanfront Rental)

Cozy Beach Cottage just 3 min. walk to the beach!

Hemingway | Jungle Hideaway

Santorini Cottage

Panoramic Marsh View, Private retreat - 33 Marsh

Pool, Elevator, Ocean Views, Steps from Ocean!

4-min walk to beach, marina, beach gear included!
Private house rentals

Architecture * La Cabaña * Beach 8 min * 2 Bdrm

Easy Beach Access across street! IOP 2BR Condo!

Mt Pleasant Cottage-Downtown, Shem Creek & Beaches

Welcome to Ohana House!

Little Bit O' Heaven

Southern Oasis by AvantStay | Pool + Walk to Beach

Private Pool, Screen Porch, 3 Master Suites!

Gorgeous 4BR | Private Pool | Balcony | W/D
Quick stats about house rentals in Isle of Palms
Total rentals
760 properties
Nightly prices starting at
$41 CAD before taxes and fees
Total number of reviews
11K reviews
Family-friendly rentals
740 properties are a good fit for families
Pet-friendly rentals
230 properties allow pets
Rentals with a pool
560 properties have a pool
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- Rentals with outdoor seating Isle of Palms
- Luxury rentals Isle of Palms
- Villa rentals Isle of Palms
- Apartment rentals Isle of Palms
- Beach house rentals Isle of Palms
- Rentals with a fireplace Isle of Palms
- Fitness-friendly rentals Isle of Palms
- Waterfront rentals Isle of Palms
- Condo rentals Isle of Palms
- Pet-friendly rentals Isle of Palms
- Rentals with a kayak Isle of Palms
- Rentals with a washer and dryer Isle of Palms
- Rentals with an EV charger Isle of Palms
- Rentals with pools Isle of Palms
- Rentals with a patio Isle of Palms
- Beachfront rentals Isle of Palms
- Rentals with a hot tub Isle of Palms
- Rentals with a firepit Isle of Palms
- Rentals with beach access Isle of Palms
- Family-friendly rentals Isle of Palms
- House rentals Charleston County
- House rentals South Carolina
- House rentals United States
- Park Circle
- Hunting Island State Park Beach
- Sullivan's Island Beach
- Bulls Island
- Middleton Place
- James Island County Park
- Waterfront Park
- The Golf Club at Wescott Plantation
- Shem Creek Park
- Angel Oak Tree
- Harbor Island Beach
- Hampton Park
- The Charleston Museum
- Driftwood Beach
- Morris Island Lighthouse
- Isle of Palms Beach
- Seabrook Island Beach
- Charleston Aqua Park
- Gibbes Museum of Art
- White Point Garden
- Seabrook Beach
- Whirlin' Waters Adventure Waterpark
- Splash Zone Waterpark At James Island County Park
- Front Beach IOP