
House vacation rentals in Saint Helena Island
Find and book unique houses on Airbnb
Top-rated house rentals in Saint Helena Island
Guests agree: these houses are highly rated for location, cleanliness, and more.
Vacation rentals for every style
Get the amount of space that is right for you.
Popular amenities for Saint Helena Island house rentals
House rentals with a pool

One Particular Harbor

Cozy Coastal Chic - Beach, Pickleball, Golf, Pets

Coastline Cottage

Marsh views with dock, pool, & elevator!

Water Views Treehouse walkable to Harbour Town

Fripp Island, Ocean Front on Tarpon with best view

Whispering Palms Cottage

Peaceful Harbour Town Treehouse with Marsh Views
Weekly house rentals

Relaxing Low Country Living

Marrakesh on the Marsh

August discounts! Views, Pet friendly, Golf Cart

The Tidewatch

The Market Croft

Modern Farmhouse near PI/MCAS and Agapae Oaks!

Grace Cottage - Your Home Away From Home!

Beautiful Water Views, Dock, Yard, Private, Quiet
Private house rentals

Marsh front home with limo cart & cards available

Waterfront Farm- 1.5 Miles from Downtown Beaufort

Little Boho Beach House ( Oceanfront Rental)

Serenity Shore Retreat-Vet-Owned-Minutes from PI

*Cozy Downtown Cottage*

Condo in Beaufort South Carolina

Newly Renovated 3 Bed/2.5 Bath 15 mins to MCRD

Historic | Walk Downtown | Open Concept | Fire-pit
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- Coligny Beach Park
- Forsyth Park
- Hunting Island State Park Beach
- Sullivan's Island Beach
- North Beach, Tybee Island
- Palmetto Dunes Oceanfront Resort
- Harbour Town Golf Links
- Shipyard Beach Access
- Middleton Place
- The Golf Club at Wescott Plantation
- Hampton Park
- Mid Beach
- The Westin Savannah Harbor Golf Resort & Spa
- James Island County Park
- Hilton Head Island Beach
- Dolphin Head Golf Club
- The Charleston Museum
- Shem Creek Park
- Tybee Beach Pier and Pavilion
- Angel Oak Tree
- Wormsloe Historic Site
- Congaree Golf Club
- Edingsville Beach
- Harbor Island Beach