
House vacation rentals in Seneca
Find and book unique houses on Airbnb
Top-rated house rentals in Seneca
Guests agree: these houses are highly rated for location, cleanliness, and more.
Vacation rentals for every style
Get the amount of space that is right for you.
Popular amenities for Seneca house rentals
House rentals with a pool

Lakeside Family & Dog Retreat Awaits! DWC

Lakefront, Private Pool, Dock, Dogs, Boats,FirePit

Pet + Family Friendly 4BR Pool House Near Furman

Golf view, lake access, 3 pools!

Mountain Laurel Retreat

Historic peaceful 1906 Farmhouse

Cottage close to Clemson

Oconee Belle w/ Pool and Mountain View+ sleeps 10
Weekly house rentals

Basement apartment in Pendleton w/ sep. entrance

Sweet and Cozy Home for Rent

Lakefront Mid-Century Dream Home / 3 mi to Clemson

Modern home near Clemson, Keowee

No cleaning fee farmhouse lake keowee near Clemson

Creekside Escape~ pool table & sleeps 8

A+ Keowee Kustom!*NO Dock!

Race Car Addict Pit Stop 3BR 3BA
Private house rentals

Keowee Cottage: lakefront home

Clemson-cation

The Yellow Quilt in Walhalla

Good Times @ Clemson / Lake Hartwell

New Waterfront House with Big Views & Private Dock

Waterfall Cove - Prime

Anchor Point, Lake Retreat - Clemson, 2-story dock

Keowee’s family house with hot tub, kayaks, & more
Quick stats about house rentals in Seneca
Total rentals
30 properties
Nightly prices starting at
$55 CAD before taxes and fees
Total number of reviews
1.6K reviews
Family-friendly rentals
20 properties are a good fit for families
Pet-friendly rentals
10 properties allow pets
Rentals with dedicated workspaces
10 properties have a dedicated workspace
Destinations to explore
- Western North Carolina Vacation rentals
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- Rentals with lake access Seneca
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- Lake house rentals Seneca
- Rentals with a washer and dryer Seneca
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- House rentals Oconee County
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- House rentals United States
- Black Rock Mountain State Park
- Gorges State Park
- Tugaloo State Park
- Helen Tubing & Waterpark
- Mountaintop Golf & Lake Club
- Table Rock State Park
- Tallulah Gorge State Park
- Bell Mountain
- Ski Sapphire Valley
- Wade Hampton Golf Club
- Jump Off Rock
- Don Carter State Park
- Victoria Bryant State Park
- Old Edwards Club
- Anna Ruby Falls
- Funopolis Family Fun Center
- Victoria Valley Vineyards
- Discovery Island
- Carl Sandburg Home National Historic Site
- Haas Family Golf
- Louing Creek
- Chattooga Belle Farm
- City Scape Winery
- Wellborn Winery