
Bed and breakfast vacation rentals in Upstate South Carolina
Find and book unique bed and breakfasts on Airbnb
Top-rated bed and breakfasts in Upstate South Carolina
Guests agree: these bed and breakfast rentals are highly rated for location, cleanliness, and more.
Vacation rentals for every style
Get the amount of space that is right for you.
Popular amenities for Upstate South Carolina bed and breakfasts
Family-friendly bed and breakfasts

#7 Rose Room - Oakland Cottage B&B
Erica and Jim are so thoughtful and amazing innkeepers! Their attention to detail was noticable at every turn, right down to the fresh baked cookie every evening! Breakfast was delicious both days! My mom is vegan/gluten free and they where delighted to make a similar dish for her while still accommodating her dietary needs, plus it tasted amazing!! Definitely recommend staying here!! 5 stars *****

Two private rooms with bathroom
Everything about our stay at Diana’s was perfect! Location, cleanliness, attentiveness and all the extras! She made us feel like family and truly cared about us having a nice and relaxing time while visiting! We will be returning guests, cannot say enough great things about this wonderful lady and her place! Go TIGERS!

Practical Elegance
We stayed for 3 nights and had a great experience at Chuck and Diane’s place. It was a home away from home….from the National Park recommendations to the great breakfasts they prepared to the stories shared about their Gatlinburg home and surrounding area. Their desire to be great hosts is evident from your first encounter with them. The bedroom and bathroom are private and cozy while the shared areas in the home are welcoming and homey. We walked to and from the strip in Gatlinburg a time or two but there are free trolleys available if you don’t want to hoof it. Chuck and Diane say that they love what they do because they make new friends along the way. I’m convinced that is true. My wife and I will easily feel like friends coming home the next time we stay with Chuck and Diane.

Great Smoky Mtns- Casino- Outdoor Adventures
Melony was Great to work with, very clear with the instructions and very responsive. The house is a beautiful place in a beautiful spot.

GreenLife Inn at Mimosa Room 202
Oh my gosh! My friend and I had a girls' weekend in the Tryon area visiting the local wineries and we stayed at the Green Life Inn, and it was a great experience! Mary's special touches were amazing! There were snacks & water in the room, top-quality soaps and shampoo were provided, and the bed linens were AMAZING! To top it all off, Mary provided quite the spread of food for breakfast. Homemade (yummy) muffins, cheesy hashbrowns with sausage, hard-boiled eggs, yogurt, fruit, juice, coffee and much more! We will definitely stay there again! Thank you Mary for your hospitality!

Lake Murray Retreat
We so enjoyed staying in Louise's beautiful home. She is such a gracious host and made us feel so comfortable. She is very communicative and we knew everything that we needed to know about our stay. The yard and lake are so beautiful. I felt like my breathing slowed down and my muscles released as soon as we pulled in each time. We were visiting my daughter at USC, so we were on campus a lot. I would love to go back to spend more time relaxing there. It was just a perfect stay!

Amazing Smoky Mt View, hottub, Snacks included
My husband and I thoroughly enjoyed our stay. It was a perfect place for two. The attached room with amenities was also thoughtful. The views were spectacular and it was easily accessible to Gatlinburg, Pigeon Forge, and the National Park. We would happily stay again.

Holly Tree Bed & Breakfast - Maggie's Room
If you are looking for a bed and breakfast experience with a beautiful mountain view, this is a great choice. Mrs. Judy is kind and friendly and served the most yummy breakfast.
Bed and breakfast rentals with breakfast

Quiet Home, Gardens, Qn BR or Single, Kitchens
Loved it Linda was great made me feel at home. Felt like part of the family. Would recommend!

Two Rooms - Sleeps 4 Guests: on beautiful FARM
WONDERFUL stay!! We had the BEST time, and so appreciate John's hospitality... what a beautiful spot to land and connect with our college aged daughter. Absolutely LOVED walking around the grounds, especially the farm and appreciated the cozy and clean accommodations!! Thanks y'all we hope to visit again!!

Creekside Inn B&B - Country Suite
We had a wonderful stay at Creekside Inn B&B . Mike was there to great us soon as we arrived and gave us a tour of the entire inn . We felt right at home , Mike suggested several spots for dinner and his wife also had several options for us to try . The restaurant we picked was a great place and was one of their recommended spots . The space was warm and inviting with ample space and great views. We had a restful night and were very pleased with the wonderful breakfast served the next morning . We also meet a nice couple from Raleigh NC who were also enjoying their stay . We will definitely be back soon for another stay , super close to I-40 Easy access in and out

HayGood Manor Bed & Breakfast - Rooms
Haygood Manor is simply amazing! There is deep history and a sense of wonderment in every room. Selena is the ultimate host! Each room is warm and welcoming. Her home is within walking distance to Abbyville's town square where there a plenty of shops and restaurants to visit. We will definitely be back as there is no way you can take in all the Haygood Manor has to offer in one visit!

The Gilded Bat B&B - Lilith Room
Erica is very nice and helpful. The Gilded Bat B&B is a unique experience and the town of Newberry is quaint with local restaurants and art shops. We look forward to returning soon

Pet Friendly, Pretty & Private Suite Near UofSC
This is a gem! Very comfortable bed and great jacuzzi tub. Christal is an amazing host—stocked fridge, so attentive, breakfast with friendly people…! The property is within walking distance to the Soda City Market, which was a blast on. Saturday morning. Highly recommend.

The Historic 1850’s Smith-Stratton Cottage
Beautiful cottage with private room and bathroom and dedicated balcony, access to living room, kitchen and dining. Ken is a gracious host. He had chocolate, beer, wine, cheese and crackers and cookies for me when I checked in. The bedroom was extremely comfortable and quiet. Ken made me a fantastic breakfast of my choice and we had a great conversation. I highly recommend this beautiful home and would loved to have stayed longer. I will definitely book the room again when I return!
Bed and breakfast rentals with a patio

Bed & Breakfast No cleaning fee
Elizabeth's place was exactly how it was described on the website. She even greeted us outside, when we arrived, and made us feel right at home! This B&B is close to the Dupont Forest and the Blue Ridge Parkway which was close to our day trip hiking destinations. Downtown Asheville and Brevard are also close by so there's plenty to do. Or if you want to sit and relax on their back porch and read a book that option is also available. We were so comfortable in their home it felt like visiting a long lost friend. Both Jim and Elizabeth had great stories to tell and also gave us a mini concert in their living room. Her weekend breakfasts were outstanding and she's a fantastic cook! I would highly recommend this place to anyone who wants to stay in this area. We will definitely be back.

B & B/Downtown/Furman/BJU/1
We have really enjoyed stay @ Lindsy’s place. It had served us well on short trip to Greenville. Especially I liked morning refreshments, coffee and bagels with cream cheese, as complimentary addition to our stay. A+++

Cabin Room @ Riverside Blue Heron Inn
Our annual "GoTo". Search is over for our Townsend Tn. vacations. Host provides clear instructions and good communications. The Breakfast is a great bonus.

Gatlinburg Family Suite! | Trolly Stop! | Wi-Fi!
This is my third stay at Joe's place in Gatlinburg. The convenient location, great amenities, and clean stay has brought me back. The location is waking distance to downtown Gatlinburg, but you can also catch the free trolly across the street and ride to the Aquarium or various food in just minutes.
Destinations to explore
- Pigeon Forge Vacation rentals
- Asheville Vacation rentals
- Augusta Vacation rentals
- Greenville Vacation rentals
- Columbia Vacation rentals
- Atlanta Vacation rentals
- Nashville Vacation rentals
- Gatlinburg Vacation rentals
- Charleston Vacation rentals
- Western North Carolina Vacation rentals
- Myrtle Beach Vacation rentals
- Charlotte Vacation rentals
- Rentals with a sauna Upstate South Carolina
- Rentals with beach access Upstate South Carolina
- Resort rentals Upstate South Carolina
- Tiny house rentals Upstate South Carolina
- Fitness-friendly rentals Upstate South Carolina
- Chalet rentals Upstate South Carolina
- Rentals with an EV charger Upstate South Carolina
- Rentals with lake access Upstate South Carolina
- Farmstay rentals Upstate South Carolina
- Treehouse rentals Upstate South Carolina
- Kid-friendly rentals Upstate South Carolina
- Rentals with a kayak Upstate South Carolina
- Hotel rentals Upstate South Carolina
- Cabin rentals Upstate South Carolina
- Loft rentals Upstate South Carolina
- Guesthouse rentals Upstate South Carolina
- Private suite rentals Upstate South Carolina
- Waterfront rentals Upstate South Carolina
- Townhouse rentals Upstate South Carolina
- Rentals with breakfast Upstate South Carolina
- Rentals with outdoor seating Upstate South Carolina
- Apartment rentals Upstate South Carolina
- Rentals with an accessible height toilet Upstate South Carolina
- Rentals with a hot tub Upstate South Carolina
- Beachfront rentals Upstate South Carolina
- Rentals with a washer and dryer Upstate South Carolina
- Rentals with a firepit Upstate South Carolina
- House rentals Upstate South Carolina
- Family-friendly rentals Upstate South Carolina
- Vacation home rentals Upstate South Carolina
- Cottage rentals Upstate South Carolina
- Condo rentals Upstate South Carolina
- Barn rentals Upstate South Carolina
- Rentals with pools Upstate South Carolina
- Smoking-friendly rentals Upstate South Carolina
- Rentals with a fireplace Upstate South Carolina
- Rentals with a patio Upstate South Carolina
- Pet-friendly rentals Upstate South Carolina
- Bed and breakfasts South Carolina
- Bed and breakfasts United States
- Yurt Rentals United States
- Yurt Rentals United Kingdom
- Castle Rentals United States
- Houseboats United States
- Holiday Caravans United Kingdom
- Private Island Rentals United States
- Farm Houses United States
- Farm Cottages United Kingdom
- Cabin Rentals Australia
- Luxury Cabins United Kingdom
- Luxury Cabins United States
- Holiday Chalets United Kingdom
- Cottage Rentals United States
- Holiday Cottages United Kingdom
- Mansion Rentals United States
- Villa Rentals United Kingdom
- Holiday Bungalows United Kingdom
- Bungalow Rentals United States
- Condo Rentals United States
- Holiday Apartments Australia
- Holiday Houses United States
- Holiday Houses United Kingdom
- Private Holiday Rentals United Kingdom
- Big House Rentals United States
- Big Cottages Australia
- Large Villas United Kingdom
- House Rentals with a Pool United States
- Cabin Rentals with a Pool United States
- Villas with a Pool United Kingdom
- Apartments with a Hot Tub United States
- Holiday Cottages with a Hot Tub United Kingdom
- Beach Cabins United States
- Beach Condos United States
- Beachfront Rentals United States
- Beach Houses United Kingdom
- Beach Villas United Kingdom
- Coastal Cottages United Kingdom
- Pet-Friendly Vacation Rentals United States
- Pet-Friendly Beach Rentals United States
- Pet-Friendly Cabin Rentals United States
- Dog-Friendly Cottages United Kingdom
- Luxury Dog-Friendly Cottages United Kingdom
- Things to do Upstate South Carolina
- Things to do South Carolina
- Food and drink South Carolina
- Nature and outdoors South Carolina
- Tours South Carolina
- Sports activities South Carolina
- Wellness South Carolina
- Entertainment South Carolina
- Art and culture South Carolina
- Sightseeing South Carolina
- Things to do United States
- Sightseeing United States
- Food and drink United States
- Tours United States
- Wellness United States
- Entertainment United States
- Art and culture United States
- Nature and outdoors United States
- Sports activities United States