
Vacation home accommodations in Upstate South Carolina
Find and book unique vacation houses on Airbnb
Top-rated vacation houses in Upstate South Carolina
Guests agree: these vacation houses are highly rated for location, cleanliness, and more.

Wake surrounded by views of the beautiful Blue Ridge Mountains in this lovely 1 bedroom vacation home.
Forget your worries in this spacious and serene space with indoor fireplace,full kitchen,laundry room,air, covered parking,large deck and outdoor fire pit/dining area. Minutes from hiking,biking,fishing,golf, 200+ waterfalls, dining, downtown Brevard, shopping,local breweries. Located between Pisgah National and DuPont State Forests. 30 minutes from Asheville airport and 20 minutes from historic Hendersonville. Brevard Music Center, Cradle of Forestry,Flat Rock Playhouse, Biltmore House nearby

Mountain Retreat - All New - Intown Waynesville NC
Your family will be close to everything when you stay at this centrally-located home in Waynesville, NC with Hot Tub, Fire pit and Game Room. This Mountain Retreat is the best of both worlds - amazing mountain views with easy walkability right in town. In the heart of the Smoky Mountains and Blue Ridge Parkway. Just 35 minutes to Asheville and Biltmore House. Closeby Harrah's Casino, Maggie Valley & Cataloochee Ski Area & Lake Junaluska. Enjoy white water rafting, skiing, hiking, Ziplining.

City Dream Spacious 2BR/2B & Walk the Heart of GVL
City escape w holiday decorations & hot cocoa bar. Enjoy 2 FULL BATHROOMS. Prime location to walk,trolley,bike downtown or to trail. This gem is 5 min walk to Bcycle/trolley @Fluor Field.10 min walk to Falls.Uber friendly.See shops-art galleries-museums-tours-eateries-breweries-outdoor activities.Newly remodeled spacious historic bldg w 10’ ceilings, wood floors & new baths.1300 sq.ft entire 1st floor.1 King &1 Queen bed.Large private patio,full kitchen/living/dining. Games & records.PARK FREE

Home for Holidays Villa Stony Woods by Asheville
The Villa at Stony Woods Estate, 4-acre estate home in the splendor of Western North Carolina, centered on an 85 acre estate. Rent the Villa or the entire property (with luxury tree house rentals) for your next memorable vacation getaway or special event. Welcome to the tranquility that comes from elevation, calming and majestic views, and the breathtaking awe of spacious, well-built masterpiece of a home designed by renowned architect, Robert Griffin. This home creates memories of a lifetime.

Studio in the heart of Greenville
We look forward to hosting you at this centrally located studio apartment only 2 miles from Furman University and 6 miles from downtown Greenville and TR, in a quiet established neighborhood beautifully landscaped. Spacious studio with sitting area & built in office, HS Wi-Fi, *NO TV*! Full size wroght iron bed with pillow top mattress, comfy couch, and lots of natural light. In unit laundry. Kitchenette amenities - toaster oven, 2 burner hot plate and hot water kettle, French Pressed Coffee.

Cozy cottage 15 mins Clemson, 7 mins lake Keowee
Has Stairs This efficiency apt has it all. Kitchen with convection micro, fridge, coffee maker & hot plate. Not a full size home, it’s an apartment. Space surrounded by Oconee County Country Club golf course. 1 mile to Walmart and shopping. 30 mins to the Blue Ridge Mountains. We are 7 mins to beautiful Lake Keowee. Please note 5 people should be family as it is tight. The person booking the property must be staying on the property. No construction equipment or trucks allowed on the property.

The Parlor #1
After family used this unit for several years, we are back in Airbnb mode as of 12/25! Updated pics coming soon! Come relax and enjoy life in the country! Our apartment is an actual renovated milking parlor! While the dairy is no longer in operation, we have beef cattle that you may see as you sit and enjoy your coffee on the front porch! There is a one queen bed but we are ok with a couple children on floor beds or couches. Just ask! We are 6 minutes from Abbeville and 12 minutes from Due We

Nantahala River 2BR - Bear Cave Boat Parade
Closest rental to the Nantahala Outdoor Center! 1.5 miles upriver. Trains daily. Read this: NO SMOKING, NO PETS, no exceptions, please don't ask. Service animal excepted. Read CANCELLATION POLICY before booking and house rules before booking. NO TRASH SERVICE in area, guest must remove when checking out. NO TRAILERS. Parking too small Two vehicles MAX. NOT SAFE for small children due to powerful water. WI-FI provided. CELL Coverage: Verizon = Excellent. T Mobile = None. ATT = Outdoors only.

Patriot Point B, an inviting studio apartment
This patriot themed studio apartment sleeps 5. The apartment includes a queen, pull out queen sofa bed, optional roll out full bed, a full kitchen, 1 bathroom, full laundry area, with areas for relaxing, bonfire and a gas grill. The apartment offers cozy patriotic decor including several historic homes in the area. It's charming and includes a large room with designated areas for the bed and living area, a kitchen and separate bath. We are minutes from downtown Spartanburg. Kerri & Brian

Sandy Plains Fountain Home | King Bed | 3 MI TIEC
2 Bedrooms - 1 king bed & 1 queen, 1 bath Efficiency kitchen ( we are testing an additional space that we have recently added as another bedroom as an extra bonus room ) there will be an extra 100$ added separately by the host for use of 3rd bedroom- 2 night minimum Detached Laundry facility on property where nature surrounds you with additional outside seating & dining . Peaceful and centrally-located 3 miles from Tryon International Equestrian Center TIEC & local wineries .

Lake House and Dock Upscale and Immaculate
Our immaculate 2020 built water-themed home is a luxury furnished lakefront 1.1 acre property on Lake Hartwell with a large boat dock. Our house enjoys amazing lake views and is perfect for the tournament fisherman, the boating enthusiast, golfers, families and those just needing to relax. We are down the street from Stonecreek Cove Golf Course in a countryside atmosphere and are comfortably close to the renowned Green Pond Landing, host to many national fishing tournaments.

Lirio Woods
Lirio Woods is located in a rural setting, 15 minutes from downtown Asheville. The spacious lower level of the house is reserved for guests and is completely private. Next door is Barn Door Ciderworks (on the web - barndoorcw.com) - guests are invited to stop by for a cider on the house and a bite to eat. Lirio Woods is perfect for exploring this spectacular part of Western North Carolina - the Blue Ridge Parkway, Biltmore Estate, Chimney Rock, hiking trails, and more.
Popular amenities for Upstate South Carolina vacation houses
Family-friendly vacation houses

Luxe Studio near Golf Course and Lakes.

LKN Lake Life

Gatlinburg Villa @ WG Smoky Mountain Resort & Spa

The Studio at Gallery339

The Nest. A lovely apartment on Lake Chatuge.

New mountain cabin moments away from attractions!

Suite #3- Creek View- Reopened since Helene

Mountainview Apartment at Sunrise Ridge
Vacation home rentals with a patio

Private mountain oasis with stunning views

Cozy-Modern Retreat with outdoor entertainment

PILOT COVE 1 BR - Modern Luxury w/ Nature!

Peaceful Mountain Cabin

Riverstone Resort 3 Bedroom Condo

Luxury Cabin w/ Hot tub, Game Room, Views!

New Waterfront Home | Amazing Views of Lake James

Straight Line Lodge. Modern. Recently Renovated
Vacation home rentals with a washer and dryer

Lake junaluska resort, easy access and convenient

Walking distance to stadium with 4 parking spots!

Sunset Retreat - Big Deck, Mountain & Lake Views!!

Wright House Retreat

Mountain Views w/ Hot Tub + Fire Pit – World’s Inn

Cozy 3 bedroom home near Downtown Asheville

Stunning Mtn Views in Western NC W/new hot tub

Rocky Ridge Base Camp @ DuPont - Bike from House!
Destinations to explore
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- Blue Ridge Parkway
- The North Carolina Arboretum
- Gorges State Park
- Table Rock State Park
- Chimney Rock State Park
- Ski Sapphire Valley
- Lake Lure Beach and Water Park
- Jump Off Rock
- Wade Hampton Golf Club
- Tryon International Equestrian Center
- Victoria Valley Vineyards
- Discovery Island
- Burntshirt Vineyards
- Carl Sandburg Home National Historic Site
- Haas Family Golf
- City Scape Winery
- Saint Paul Mountain Vineyards
- Overmountain Vineyards
- Russian Chapel Hills Winery
- Wellborn Winery
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