
Guesthouse vacation rentals in Charleston County
Find and book unique guesthouse rentals on Airbnb
Top-rated guesthouses in Charleston County
Guests agree: these guesthouses are highly rated for location, cleanliness, and more.
Vacation rentals for every style
Get the amount of space that is right for you.
Popular amenities for Charleston County guesthouses
Family-friendly guesthouses

Island Oasis—Near Downtown

Charleston's Coolest Neighborhood

Bungalow Under The Oaks

Green Garden Studio @greengardenstudio2017

Liz Lane Cottage- entire guesthouse

Romantic Beach Style Cottage close to everything!

Mother in Law in James Island Riverland Terrace

5 STAR 1bd/1ba Shem Creek Retreat in #1 MtP area!
Guesthouses with a patio

*Old Village/Shem Creek Charmer*NEW 2BR Guesthouse

Stylish Carriage House+Pool House

Coastal Charm: Village Hideaway

Spacious 1 bedroom cottage in Avondale

Driftwood Cottage

My Happy Place

The Violet Villa w/no cleaning fee

Cozy Cottage! 5 mins from Kiawah!
Guesthouse rentals with a washer and dryer

Peaceful Garden Cottage Retreat

Cozy Apartment in Mount Pleasant

Cozy Cottage w Games, Firepit, Grill, and More!

Private Coastal Cottage-Near Beaches & Charleston!

Cozy Park Circle, Charleston Guest House

#1 SC AIRBNB IN MT. PLEASANT OLD VILLAGE. BEACHES!

Serene Location - Next to Hampton Park: Haven Hom

The Guesthouse at Old Orchard
Destinations to explore
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- Hunting Island State Park Beach
- Sullivan's Island Beach
- Middleton Place
- Hampton Park
- The Golf Club at Wescott Plantation
- James Island County Park
- Shem Creek Park
- The Charleston Museum
- Edingsville Beach
- Harbor Island Beach
- Yeamans Hall Club
- Angel Oak Tree
- Sandy Point Beach
- Waterfront Park
- Isle of Palms Beach
- Secession Golf Club
- Morris Island Lighthouse
- Hunting Island Beach
- Seabrook Island Beach
- Seabrook Beach
- Gibbes Museum of Art
- White Point Garden
- Driftwood Beach
- Deep Water Vineyard
- Things to do Charleston County
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