
Guesthouse vacation rentals in Charleston County
Find and book unique guesthouse rentals on Airbnb
Top-rated guesthouses in Charleston County
Guests agree: these guesthouses are highly rated for location, cleanliness, and more.
Vacation rentals for every style
Get the amount of space that is right for you.
Popular amenities for Charleston County guesthouses
Family-friendly guesthouses

Island Oasis Hideaway | Easy Beach & City Access

CHS Guest house w/ Pool on Golf Course

Charleston's Coolest Neighborhood

Cozy Lady Ashley Studio Flat on James Island

The Olive FROG in Park Circle! 3 min walk to FUN!

Bungalow Under The Oaks

Riverland Terrace Guesthouse

Charming Charleston StudioOne!
Guesthouses with a patio

*Old Village/Shem Creek Charmer*NEW 2BR Guesthouse

Quaint Cottage Studio in Ashley Forest (Avondale).

Studio 77 in dt Charleston with bikes

Farm Stay w Gardens, Cute Animals, Firepit + Porch

Coastal Charm: Village Hideaway

Driftwood Cottage

My Happy Place

The Violet Villa w/no cleaning fee
Guesthouse rentals with a washer and dryer

Cozy Apartment in Mount Pleasant

Cozy Cottage w Games, Firepit, Grill, and More!

Summerville’s Tiny Oak Hideaway

#1 SC AIRBNB IN MT. PLEASANT OLD VILLAGE. BEACHES!

Serene Location - Next to Hampton Park: Haven Hom

The Guesthouse at Old Orchard

Guesthouse Convenient to Charleston, Shem Creek, and Beaches

Old Mt. Pleasant/Shem Creek close to Sullivans/DT
Destinations to explore
- RV rentals Charleston County
- Beachfront rentals Charleston County
- Rentals with a washer and dryer Charleston County
- Villa rentals Charleston County
- Rentals with breakfast Charleston County
- Fitness-friendly rentals Charleston County
- Pet-friendly rentals Charleston County
- Rentals with beach access Charleston County
- Condo rentals Charleston County
- Rentals with an EV charger Charleston County
- Tiny house rentals Charleston County
- Rentals with a kayak Charleston County
- Apartment rentals Charleston County
- Townhouse rentals Charleston County
- Private suite rentals Charleston County
- Rentals with an accessible height bed Charleston County
- Rentals with a patio Charleston County
- Family-friendly rentals Charleston County
- Rentals with pools Charleston County
- Rentals with lake access Charleston County
- Rentals with a fireplace Charleston County
- House rentals Charleston County
- Hotel rentals Charleston County
- Bed and breakfasts Charleston County
- Rentals with an accessible height toilet Charleston County
- Waterfront rentals Charleston County
- Rentals with a hot tub Charleston County
- Rentals with outdoor seating Charleston County
- Luxury rentals Charleston County
- Rentals with a firepit Charleston County
- Guesthouse rentals South Carolina
- Guesthouse rentals United States
- Park Circle
- Hunting Island State Park Beach
- Sullivan's Island Beach
- Bulls Island
- Middleton Place
- James Island County Park
- Waterfront Park
- The Golf Club at Wescott Plantation
- Shem Creek Park
- Angel Oak Tree
- Hampton Park
- Harbor Island Beach
- Secession Golf Club
- The Charleston Museum
- Driftwood Beach
- Morris Island Lighthouse
- Isle of Palms Beach
- Seabrook Island Beach
- Hunting Island Beach
- Charleston Aqua Park
- The Beach Club
- White Point Garden
- Gibbes Museum of Art
- Seabrook Beach
- Things to do Charleston County
- Sports activities Charleston County
- Nature and outdoors Charleston County
- Tours Charleston County
- Sightseeing Charleston County
- Art and culture Charleston County
- Food and drink Charleston County
- Things to do South Carolina
- Sports activities South Carolina
- Art and culture South Carolina
- Nature and outdoors South Carolina
- Wellness South Carolina
- Entertainment South Carolina
- Food and drink South Carolina
- Sightseeing South Carolina
- Tours South Carolina
- Things to do United States
- Food and drink United States
- Tours United States
- Sightseeing United States
- Wellness United States
- Art and culture United States
- Entertainment United States
- Nature and outdoors United States
- Sports activities United States