Guesthouse vacation rentals in Greenville

Find and book unique guesthouse rentals on Airbnb

Top-rated guesthouses in Greenville

Guests agree: these guesthouses are highly rated for location, cleanliness, and more.

0 of 0 items showing

1 of 3 pages

Guest favourite

Guesthouse in Greenville

4.98 out of 5 average rating, 102 reviews

The Spring Valley Retreat

Newly renovated in 2021, very comfortable guesthouse located in a quiet neighborhood just 10 minutes from downtown Greenville. Created by highly experienced bed and breakfast owners, this space is carefully crafted to be a relaxing, restful place for travelers. Two bedrooms, a kitchen with brand-new appliances, dining area, smart TV, a desktop space, WiFi, and an outdoor porch spot to enjoy nice weather days. Note that if you search the address on Google, it will pull up photos before renovation

Guest favourite

Guesthouse in Greenville

4.92 out of 5 average rating, 666 reviews

Historic 19th Century Cabin/Guest House

This 19th century cabin is your perfect cozy getaway. This guest house is located on a 3.5 acre property, secluded from the historic neighborhood, though it's just 3 miles from downtown Greenville and the Bon Secours Wellness Arena. Less than a mile to the Swamp Rabbit Trail, this cottage is perfect for jaunts to downtown Greenville, Furman University, Paris Mountain, Travelers Rest and Unity Park! Micro weddings and events are available upon request and approval with applicable fees applied.

Top guest favourite

Guesthouse in Travelers Rest

4.99 out of 5 average rating, 110 reviews

The Travelers Loft

Light and airy contemporary guest house with upscale furnishings, nestled on 40 acres of woodland and meadows. Perfect for 2-4 guests. 2.5 miles from downtown Travelers Rest and the 'Swamp Rabbit Trail'. Great for biking or walking. 25 minutes to the city of Greenville and 45 to the mountains of Asheville, NC. Located less than 30 minutes from the Greenville Airport. This second story guest house has private parking, and a beautiful deck for grilling out or just relaxing after a busy day.

Top guest favourite

Guesthouse in Fountain Inn

4.98 out of 5 average rating, 100 reviews

Upscale cottage in Downtown Fountain Inn

All new cottage/studio apartment. 5 minutes to CCNB amphitheater at Heritage Park, 10 minutes to downtown Simpsonville, 25 minutes to Bon Secours Wellness Arena in downtown Greenville. 20 minutes from GSP airport. Close to Hillcrest Hospital and Bon Secours in Simpsonville. 25 minutes from Presbyterian College, 30 minutes from Furman University. Guest have access to partially fenced backyard as well as full access to private cottage. Host lives on property! There is NO Bathroom Door.

Top guest favourite

Guesthouse in Greenville

5 out of 5 average rating, 412 reviews

The Cottage at Old Oaks Farm

Built in the early 1900's, this serene cottage is located approximately one mile from Furman University at the base of Paris Mt. It has been lovingly improved, but the floors are a bit slanted and no corner is exactly square. Located in a neighborhood on a five acre farm, it consists of three large rooms, comfortably furnished and lots of natural light. The cottage is convenient to downtown Greenville(5 miles),Travelers Rest, Furman, and the Swamp Rabbit Trail. No pet fee or cleaning fee.

Top guest favourite

Guesthouse in Brevard

4.99 out of 5 average rating, 103 reviews

Probart House - historic and 1 block from Main St

Location is everything! Enjoy a luxurious stay at this guesthouse located one block from downtown Brevard. Located at the former historic Red House Inn, this home has everything from a soaker tub, fireplace, towel warmer, heated flooring, kitchenette, king sized bed & pull out twin sofa. Only 1 block from Main St. shops/restaurants/coffee shops/music venues. The Ecusta Trail is also across the street. Cyclists are welcome to use our bike wash and access our private bike storage area.

Top guest favourite

Guesthouse in Campobello

4.97 out of 5 average rating, 117 reviews

Bungalow on a 3 acre mini farm

This is a tree house like bungalow in beautiful Campobello SC. Enjoy a peaceful, rural retreat that is central to Upstate SC and Western NC. We are about 5 miles to downtown Landrum SC, 25 minutes to Spartanburg SC, 40 minutes to Greenville SC, 45 minutes to Asheville NC, and about 22 minutes to the Tryon Equestrian Center in NC. Inside the unit, downstairs is the kitchen, dining area, and bathroom, Upstairs in the loft are 4 different beds (Queen, Three Singles) &.a common area.

Top guest favourite

Guesthouse in Greenville

4.94 out of 5 average rating, 206 reviews

Gorgeous Downtown Studio & Dog Friendly!

This has moved to 30 days+ starting Jan 2024! Message me if you're trying to book and your dates aren't showing available! This location is unmatched. Steps from Falls Park which includes one of the most majestic waterfalls, green space and Swamp Rabbit Trail for all your running/walking and biking needs. Directly across the street from the Greenville Drive baseball stadium. One block from all the finest restaurants, shopping and best attractions downtown offers.

Top guest favourite

Guesthouse in Greenville

4.97 out of 5 average rating, 236 reviews

Greenville With A View!

ONLY 10-15 MINUTE DRIVE TO THE HEART OF BEAUTIFUL DOWNTOWN GREENVILLE! We are only 11 miles to GSP Airport; 6 miles to Greenville Downtown Airport; and 10 minutes to the Swamp Rabbit Trail. We are minutes to Furman University, Bob Jones University, North Greenville University and Clemson University is only 45 minutes away. We are tucked away open top of Paris Mountain. If you want to bike, hike, paddle, swim, boat or just soak it all in, start here!

Superhost

Guesthouse in Taylors

4.98 out of 5 average rating, 128 reviews

Scandinavian Cottage

This cottage renovation has been uniquely crafted to host travelers with a modern, minimalistic, rustic, Scandinavian experience. Decorated with original wood accents, this adorable studio guesthouse is perfect for a romantic getaway, business trip or a peaceful place to unwind. It's ideally located between the well-desired cities of Greenville and Greer, SC. Foodies and adventurers alike will fall in love with this region and are sure to return.

Superhost

Guesthouse in Greenville

4.81 out of 5 average rating, 308 reviews

1950's Cottage- Close to Downtown & Furman

My 50's cottage is charming and cozy, very clean and convenient to downtown, Traveler's Rest & Furman University. Located in a quiet space with parking right beside the cottage. We are a straight shot to downtown Greenville in about 7 minutes. I listen to my awesome guests and have made a few recent updates: new electrical outlets in bathroom, new larger hot water heater for longer showers!

Top guest favourite

Guesthouse in Greenville

5 out of 5 average rating, 122 reviews

Sally's Cottage

Couples retreat located 6 miles from downtown Greenville and the Swamp Rabbit Trail in a comfortable country setting. Wake up to a beautiful woods view through a large bay window and wildlife that surrounds the cottage (deer, birds and squirrels). Experience the beauty of the country in the city! Enjoy the eclectic collection of art and design in this cute little cottage.