
House vacation rentals in James Island
Find and book unique houses on Airbnb
Top-rated house rentals in James Island
Guests agree: these houses are highly rated for location, cleanliness, and more.
Vacation rentals for every style
Get the amount of space that is right for you.
Popular amenities for James Island house rentals
House rentals with a pool

SullyChic 5 Bedroom | Private Lux Pool Park Circl

Share-in Dipity Refined 4 bedrooms pool not heated

2500SF Downtown 1849 home w/ pool!

Private Entrance Suite w/ pool, 5 min from beach

Beautiful 2BD/2BA Seabrook Island Villa

Pristine Townhouse - Beach, Charleston, Pool, Fun

Family Retreat | Pool | Game Room | Fenced Yard

Family Friendly House in Charleston’s Park Circle
Weekly house rentals

Quirky/Charleston location cozy Folly lg fenced yd

Heron House circa 1950 - steps to beach & town!

The Blue Bungalow- Central Park Circle

Waterfront Home 5 minutes From Downtown Charleston

Boho Bungalow | Private Oasis - Sleeps 4!

Charming 2BR | Near Downtown, Airport & Beaches

Modern four-bedroom home centrally located

Petite Maison- guesthouse, Downtown Charleston
Private house rentals

Charming Charleston home

Waterfront Modern Luxury Design & Chef's Kitchen

Charming 2 Bed/2Bath Newly Renovated-Location!

Red Sunsets | 2 Master Bedrooms | Heated Pool

Luxe Pool Retreat | Between Folly + Downtown CHS

Hemingway | Jungle Hideaway

Santorini Cottage

James Island Creek Retreat | On the Water |
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- Family-friendly rentals James Island
- Rentals with beach access James Island
- Rentals with a patio James Island
- Rentals with breakfast James Island
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- Rentals with pools James Island
- Villa rentals James Island
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- Townhouse rentals James Island
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- Rentals with lake access James Island
- Private suite rentals James Island
- Bed and breakfasts James Island
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- Apartment rentals James Island
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- Guesthouse rentals James Island
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- Rentals with a washer and dryer James Island
- House rentals Charleston County
- House rentals South Carolina
- House rentals United States
- Park Circle
- Hunting Island State Park Beach
- Sullivan's Island Beach
- Bulls Island
- Middleton Place
- James Island County Park
- Waterfront Park
- The Golf Club at Wescott Plantation
- Shem Creek Park
- Angel Oak Tree
- Hampton Park
- Harbor Island Beach
- Secession Golf Club
- The Charleston Museum
- Bull Point Beach
- Driftwood Beach
- Morris Island Lighthouse
- Isle of Palms Beach
- Seabrook Island Beach
- Hunting Island Beach
- Charleston Aqua Park
- The Beach Club
- Gibbes Museum of Art
- White Point Garden
- Things to do James Island
- Sightseeing James Island
- Food and drink James Island
- Tours James Island
- Nature and outdoors James Island
- Sports activities James Island
- Things to do Charleston County
- Nature and outdoors Charleston County
- Tours Charleston County
- Sports activities Charleston County
- Food and drink Charleston County
- Art and culture Charleston County
- Sightseeing Charleston County
- Things to do South Carolina
- Art and culture South Carolina
- Food and drink South Carolina
- Tours South Carolina
- Sports activities South Carolina
- Nature and outdoors South Carolina
- Entertainment South Carolina
- Sightseeing South Carolina
- Wellness South Carolina
- Things to do United States
- Entertainment United States
- Tours United States
- Nature and outdoors United States
- Art and culture United States
- Wellness United States
- Food and drink United States
- Sightseeing United States
- Sports activities United States