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Vacation rentals in Los Santos Province

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Top-rated vacation rentals in Los Santos Province

Guests agree: these stays are highly rated for location, cleanliness, and more.

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Guest favourite
A tranquil exterior view of a private terrace featuring two wooden chairs with colorful stripes. A small side table is positioned between them, and the space is framed by lush greenery and a canopy roof. The entrance includes large glass doors opening to the interior.
Cabin in Playa Guánico Abajo
4.93 out of 5 average rating, 27 reviews

Guanico Beach Cabin

Ideal room for two people a few steps from Guanico beach. Relax in this quiet and bright space. Room with double bed, air conditioning and ceiling fan. They have a terrace with chairs and hammocks. Outdoor sanitary block with shower and private bathroom. We don't have wifi/Starlink in our accommodations because the signal is bad in the area. The most recommended option is to buy a MOBILE CHIP (costs $1.50) and its $6 recharge that allows you to have unlimited wifi on your cell phone for 7 days

Top guest favourite
The rustic wooden cabaña is nestled among trees, featuring a sloped roof and a cozy porch illuminated by warm lights. A vibrant hammock is draped beneath the porch, surrounded by lush greenery and a gravel path, showcasing a tranquil outdoor atmosphere.
Cabin in Cambutal
4.93 out of 5 average rating, 60 reviews

Charming Cabaña on the beach

If you're looking for a place to relax and experience the magic of Cambutal with its lush jungle and stunning beaches, look no further. Nestled amongst the trees and overlooking one of the best swimming bays around, this rustic wooden cabaña has everything you need to make your stay unforgettable. Wake up to the sounds of the ocean on your doorstep, spend your days swimming in the warm ocean, or try other exciting activities, such as horse riding, hiking, yoga, surfing, diving and snorkelling.

Top guest favourite
A beachfront house features a thatched roof and is elevated on stilts, surrounded by lush greenery and palm trees. The structure showcases a spacious porch with wooden railings, offering a shaded area for relaxation and enjoying the natural landscape.
Home in Cambutal
5 out of 5 average rating, 15 reviews

Beachfront Gem w/ Ocean Views & Prime Surf Access

Welcome to your slice of beachfront paradise! Our home sits right on Cambutal's beautiful shoreline. Gorgeous ocean views greet you from every window, while the gentle rhythm of waves creates the perfect soundtrack for your stay. We've equipped the house with Starlink WiFi and a large dining table that doubles as an ideal workspace, making this a perfect retreat for both vacationers and remote workers. The house feels like a real home – comfortable, clean, and ready for your beach memories.

Superhost
A shaded patio area features comfortable seating arrangements with dark wicker chairs and a matching table. An oceanfront saltwater pool is visible with loungers arranged beside it. Lush palm trees sway gently in the background against a clear blue sky.
Villa in Cambutal
4.86 out of 5 average rating, 7 reviews

Casa Almendra

A 3-bedroom luxury villa located on the pristine beaches of Cambutal, Panama. This beachfront paradise offers everything you need for a truly unforgettable stay... A spacious and elegantly designed living area, an open-concept kitchen, fully equipped with top-of-the-line appliances and breathtaking ocean views, and an oceanfront saltwater pool surrounded by comfortable loungers. Entirely off-grid with a state-of-the-art solar power system, your stay is not only luxurious but eco-friendly.

Guest favourite
A modern tropical home is set amid lush greenery, featuring an expansive deck that connects to a serene pool. Large glass doors provide a view of the inviting interior and allow natural light to fill the space. Mountains and trees frame the backdrop.
Home in Playa Venao
4.97 out of 5 average rating, 59 reviews

Casa Samambaia - sea view tropical paradise w pool

With a modern tropical design, this home features a cozy living room and a stylish kitchen at the center of the social area. Open the glass doors to immerse yourself in open-concept living, seamlessly blending the indoors with the main terrace and the pool, all oriented towards the ocean view. With two en-suite bedrooms with AC and fans, the house is immersed in nature, green mountains, and a lovely garden, everything 5 minutes from the beach center.

Guest favourite
The modern house is surrounded by lush greenery, featuring a spacious wooden deck with lounge chairs and a private pool. Sliding glass doors enhance the connection with nature, while a covered terrace provides shaded seating areas for relaxation.
Home in Playa Venao
4.93 out of 5 average rating, 54 reviews

Casa Pelicano - Tropical house w pool and seaview

Welcome to Casa Pelicano! Indulge yourself in a retreat with breathtaking views of the ocean and mountains from every corner. Unwind in the private refreshing pool, where the turquoise waters seem to blend seamlessly with the horizon. The stylish interior features open-plan living spaces, perfect for entertaining or relaxing. Whether you're soaking up the sun or gazing at the moonlit ocean under the stars, this home is your ultimate escape.

Top guest favourite
A small bungalow stands between palm trees, featuring a spacious terrace with hammocks. The exterior showcases a surfboard mounted on the wall, and large glass doors offer views into the interior. The warm light of sunset illuminates the scene.
Bungalow in Guánico Abajo
5 out of 5 average rating, 16 reviews

Surfside Bungalows - No. 3.

Beautiful small bungalow right on the beach with a unique location between the ocean and the river. The house comes with a private kitchenette and bathroom and a nice terrace at the front. A ladder leads up to the comfortable queen size loft bed which offers a beautiful view into the surrounding palmtrees and the sunrise over the ocean. For those who need to work, there is Starlink internet available.

Top guest favourite
The two-story house is framed by lush greenery, featuring large glass doors that open to a spacious patio. Comfortable seating areas are provided, accompanied by tropical plants. Warm outdoor lighting hangs above, enhancing the inviting ambiance, while views of the sea are visible through the glass.
Home in Cambutal
5 out of 5 average rating, 22 reviews

Beach side stay at Casa Blanca

This beautiful two bedroom, double-storey house sits in one of the best locations around, nestled amongst the trees and overlooking a stunning swimming bay in the tropical paradise of Cambutal. Perfectly situated, you will have the warm Pacific Ocean literally on your doorstep, as well as easy access to the highlights of a beach holiday - surfing, swimming, sunsets and more.

Guest favourite
Villa in El Ciruelo
4.92 out of 5 average rating, 13 reviews

Villa Almanglar - Tropical Home with Pool and View

Escape to 'Al Manglar', where tranquility meets luxury. Enjoy breathtaking views of the mangroves, beach, and ocean from your private infinity pool. This spacious 2-bedroom villa offers king beds, private bathrooms, and a fully equipped kitchen. Perfect for remote work with a dedicated co-working space. Just 7 minutes from Playa Venao, this is your ultimate coastal getaway.

Guest favourite
A spacious sleeping area features a large bed with a white comforter, flanked by two woven pendant lights. Natural wood accents are present in the furniture, including a slatted wooden ceiling and a wall-mounted television, with large windows allowing ample natural light.
Cabin in Playa Venao
4.91 out of 5 average rating, 34 reviews

Dos Mares Venao Village - Cabin

Desconecta de tu rutina y disfruta de la naturaleza. Nuestras Cabañas son amplias, cómodas, con mucho estilo y de alta calidad. La cama king invita a descansar. Además tenemos doble lavado, televisión, ducha y baño separado y una terraza amplia. En nuestro bar puedes disfrutar de los mejores desayunos. Si deseas también te lo llevamos directo a tu cabaña - como lo deseas!

Guest favourite
The villa is nestled within a lush tropical garden, featuring a private pool with clear, inviting water. Lounge chairs are positioned beside the pool, surrounded by greenery. Large windows illuminate the house, which offers views of the serene outdoor environment.
Villa in Pedasí District
4.86 out of 5 average rating, 177 reviews

Charming beach villa Pedasi, Panama

Villa in the Destiladeros Beach Pedasi (3min walk), private garden and private pool only for the guests of the villa. Very quiet place, secure. For people who are looking for a hidden place, far from the crowd but with all the commodities around (markets in Pedasi village 10min driving, several beaches , little restaurants...). Just to enjoy nature with all the comfort.

Top guest favourite
A bright bedroom is displayed, featuring a spacious bed covered with a textured white blanket. A television is mounted on the wall opposite the bed. Natural light floods through large windows, accompanied by sheer curtains. A cozy orange chair and potted plant add a touch of warmth.
Tiny homes in Playa El Jobo
4.92 out of 5 average rating, 13 reviews

Little home near to the beach -Las Tablas

10 min drive- Las Tablas Get away from it all when you stay under the stars. A room very close to the sea, with an open kitchen that will allow you to disconnect and enjoy the view and nature in Las Tablas. You can plan to visit nearby beaches or take a walk through Pedasí, 30 minutes from Las Tablas.

Popular amenities for Los Santos Province vacation rentals