
House vacation rentals in Los Santos Province
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Top-rated house rentals in Los Santos Province
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Seaside Sanctuary • Steps to Surf • Fast Internet
Wake up to the rhythmic sounds of waves steps from your bed in this intimate beachfront paradise. Our charming one-bedroom home sits directly on Cambutal's pristine shoreline, offering ocean views and instant beach access. Relax on your private terrace with morning coffee as the sun rises, cook meals in the fully-equipped kitchen, and fall asleep to the soothing sounds of the surf. With Starlink internet, you can stay connected while experiencing the perfect blend of seclusion and convenience.

3 min to Pedasi, 5 min to the Beach, Private Pool!
Your family will be close to everything when you stay at this centrally-located place. Outfitted with room to sleep 6 and a fenced yard for your dog, Casa Catch and Relax has it all! Look us up online, Casa Catch and Relax You'll Love - Beach access a short drive or walk away (3 min drive, 10 min walk) - Central to town and local restaurants - Private, fenced outdoor space with pool - Cool days and nights with A/C in every room - Fully equipped kitchen and tons of sleeping space - Wifi

Casa - Domaine De La Rose
Welcome to paradise ! Beautiful home with private pool and a large yard - amazing for entertaining family/ friends 1 master bedroom with full bath with jacuzzi, french doors to terrace 1 queen bed with full bath -1 double/ single bunk bed with full bath Open dining , kitchen and living room Full access to Andromeda Beach Club Full restaurant & bar - always something to do! Massive infinity pool with steps to the Pacific Ocean !! Beach is very beautiful and private and miles to explorer

Peaceful Pedasi
Peaceful Pedasi. Get completely away from the city and forget the rest of the world exists. Pedasí is a town and corregimiento situated on the south-eastern tip of the Azuero Peninsula on Panama’s Pacific coast. And although remote enough to feel protected from the stresses of life, Pedasi offers wonderful dining and shopping. Our home offers a full functioning kitchen, large dining space, 5 Bedrooms, 4 Bathrooms, 2 car garage, private pool, and cabana with your own view of the ocean.

NinaHouse, spacious and cool house in Chitré.
House just for you, now with a water tank! Up to 7 people, spacious and in one of the best areas of Chitré, quiet and family-friendly, access to the pool in the social area, parks and courts, close to everything: supermarkets, casino, bus; come to Chitre and enjoy typical meals, crafts; plan your walks and visit the best beaches: Pedasi, Venao, Isla Iguana, you can work from NinaHouse with fast internet. We now have air conditioning in the living room for your comfort.

Pedasí, Los Destiladeros Beach / Casa Serena
❤ Welcome to Casa Serena, escape to our stunning 3-bedroom ocean view house, perfectly located in Playa Los Destiladeros, an area of beautiful beaches in Pedasí. This unique retreat offers a blend of modern luxury and coastal charm, ensuring an unforgettable vacation experience for you and your loved ones. Book your stay today and experience the magic of Casa Serena. Create lasting memories with your family and friends in this perfect ocean view escape.

Casa Gerard
A stylish, modern beach house perched above the Pacific Ocean and a large stylish pool. Ample space with 3 bedrooms with en-suite bathrooms, large open living space with a fully equipped kitchen, giving onto a large wooden deck. A beach house with a pool in a modern style located on the hill overlooking the Pacific Ocean. It has 3 bedrooms, each with its own bathroom. It has an open living room and a well-equipped kitchen. It has a large deck to enjoy.

Casa Samambaia - sea view tropical paradise w pool
With a modern tropical design, this home features a cozy living room and a stylish kitchen at the center of the social area. Open the glass doors to immerse yourself in open-concept living, seamlessly blending the indoors with the main terrace and the pool, all oriented towards the ocean view. With two en-suite bedrooms with AC and fans, the house is immersed in nature, green mountains, and a lovely garden, everything 5 minutes from the beach center.

Casa Pelicano - Tropical house w pool and seaview
Welcome to Casa Pelicano! Indulge yourself in a retreat with breathtaking views of the ocean and mountains from every corner. Unwind in the private refreshing pool, where the turquoise waters seem to blend seamlessly with the horizon. The stylish interior features open-plan living spaces, perfect for entertaining or relaxing. Whether you're soaking up the sun or gazing at the moonlit ocean under the stars, this home is your ultimate escape.

Country House Like in the City / La Casita
Casa fresca, con árboles, naturaleza y portales p/ descansar, cámaras de seguridad afuera Ubicación céntrica, cerca de malls, restaurantes, buses y ciclovía. Entrada privada, estacionamientos, cocina completa, mobiliario completo, baño, TV HD con cable, AC en recámara, agua caliente y Wi-Fi. ENG, PORT, FRAN and ITA Spoken! Contamos con un pozo de agua y sistema de purificación de agua por ósmosis inversa: agua segura, potable y purificada!

Villa La Jungla featuring a New Pool
Escape to this serene, private retreat just minutes from Pedasí, Playa Venao, and stunning beaches. Perfect for 4–8 guests, the home features spacious en-suite bedrooms with quality linens, a fully equipped kitchen, and a newly resurfaced infinity pool. Enjoy total privacy, comfort, and easy access to local adventures. Whether you're here to surf, explore, or relax, this is your ideal home base for a peaceful and memorable stay.

A minimalist Casita in Pedasi
Imagine a peaceful casita with ocean views and a nearby pool house boasting an edgeless pool overlooking the ocean. Plus, you have your own private beach. Inside, you will find an open-concept living space adorned with simple yet stylish furnishings, designed for relaxation and comfort. It's the perfect blend of tranquility, peaceful seclusion and breathtaking natural beauty. Gated community, 24 hour security
Popular amenities for Los Santos Province house rentals
House rentals with a pool

Modern Beach Home with pool and hot tub

Yellowfin Casa 3

Beachfront home on Playa Venao + private pool

Nearly Oceanfront: Blue 3 Bedroom Spacious Villa

Casa Maitri: Panoramic Ocean View, Pool, Near Surf

Oceanfront Loft with Private Beach & Pool

Casa Del Amor in Pedasi, Panama Oceanfront paradise

Pedasí: Andromeda Boroda 4-6 p. Beach, swimming pool
Weekly house rentals

House "Las Marias" / Renewed bathroom

Beautiful House in Chitre with Pool

House for groups/Perfect for Local Parties

Pedasí, Earth House Casa Alegre / 3BR

Yayo's Place

Beautiful House for Rent in Downtown Chitré

Concha House at Luna Negra

Cozy house available for rent – Las Tablas
Private house rentals

Casa Amarilla-Cozy 2Bed/1Bath/Pocri, Las Tablas

Ocean View, Ocean View El Ciruelo

Dorado Retreat Estate in Cañas

Casa Iguana 2 - 2 queen beds, 2 sets bunk beds

CASA ROSA 49' - Venao Beach

Casa Luna 2 bdrm 2 bath walk to square!

Elegance and comfort in one place

Charming Accommodation in Las Tablas
Destinations to explore
- Smoking-friendly rentals Los Santos Province
- Pet-friendly rentals Los Santos Province
- Waterfront rentals Los Santos Province
- Rentals with beach access Los Santos Province
- Rentals with a washer and dryer Los Santos Province
- Bed and breakfasts Los Santos Province
- Rentals with a hot tub Los Santos Province
- Villa rentals Los Santos Province
- Rentals with an accessible height bed Los Santos Province
- Rentals with pools Los Santos Province
- Condo rentals Los Santos Province
- Hotel rooms Los Santos Province
- Family-friendly rentals Los Santos Province
- Rentals with a patio Los Santos Province
- Beachfront rentals Los Santos Province
- Rentals with outdoor seating Los Santos Province
- Guesthouse rentals Los Santos Province
- Rentals with a firepit Los Santos Province
- Boutique hotels Los Santos Province
- Apartment rentals Los Santos Province
- House rentals Panama





