Hotel vacation rentals in South Carolina

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Top-rated hotels in South Carolina

Guests agree: these hotels are highly rated for location, cleanliness, and more.

Guest favourite
Resort in Myrtle Beach
1st Floor/King Bed & Starbucks Grand Cayman Resort
STARBUCKS ON SITE!!😎 There's no waiting for elevators😎 with a Ground floor unit located @ Grand Cayman Oceanfront Resort & beautifully decorated sleeps 4 with a comfy 🫅king bed and 👸queen sofa sleeper, a south side ocean view and an efficiency kitchen. It is a spacious studio condo. Indoor parking😎 just steps from the room. The resort has a 4 story waterslide, lazy river, hot tubs, pools, tiki bar.😎 The famous River City Bar & Grill next to the resort voted best hamburgers on the beach!
Nov. 16 – 23
$191 CAD per night
4.79 out of 5 average rating, 204 reviews
Guest favourite
Resort in Myrtle Beach
Ocean View, Private Balcony, Renovated Suite
Ocean front, one bedroom suite within the Carolina Winds Resort. Enjoy a beautiful ocean view from your private balcony. Guests will have access to 2 pools (one indoor), 3 hot-tubs, a lazy river and a kiddie-pool. The resort offers direct beach access, seasonal on-site bar/restaurant & Snack Shack. The property is smoke-free, with coin operated laundry & free parking. This newly renovated unit is equipped with a full kitchen, Queen Beds, a Murphy Bed, 2 Smart TVs, a full bath, and free WiFi.
Nov. 8 – 15
$145 CAD per night
4.95 out of 5 average rating, 108 reviews
Guest favourite
Boutique hotel in Charleston
INDIGO room at Pinckney
Welcome to the INDIGO room. This historic INN boasts 5 charming rooms with exterior access at the heart of the market and stables. Please click our bio photo to view all rooms, rates & reviews. You will enjoy a King bed, private bath, wifi, TV and a Fireplace in cooler months. Complimentary snacks, pastries and beverages. INDIGO is located on the second floor, you will need to climb stairs. We do not offer onsite parking but convenient parking lots are all within 1-2 blocks. $20-30 per night.
Dec. 27 – Jan. 3
$464 CAD per night
4.94 out of 5 average rating, 134 reviews

Popular amenities for South Carolina hotels

Family-friendly hotels

Guest favourite
Hotel room in Edisto Island
Wyndham Ocean Ridge - Edisto Island ** 1 Bedroom
Jan. 6 – 13
$583 CAD per night
5.0 out of 5 average rating, 12 reviews
Resort in Hilton Head Island
Oceanfront, Brand new Luxury Suite!!
Apr. 6 – 13
$467 CAD per night
5.0 out of 5 average rating, 4 reviews
Resort in Myrtle Beach
2 Bdrm - South Beach Resort - Myrtle Beach, SC
May 2 – 7
$383 CAD per night
New place to stay
Resort in Myrtle Beach
Myrtle Beach, Ocean Front Apt, July 7- July 14
Jan. 19 – 26
$289 CAD per night
New place to stay
Guest favourite
Hotel room in Clemson
Two private rooms with bathroom
Apr. 21 – 28
$493 CAD per night
5.0 out of 5 average rating, 7 reviews
Superhost
Resort in Myrtle Beach
1 bdrm condo, South Beach Resort, Beach Access
Nov. 10 – 17
$584 CAD per night
5.0 out of 5 average rating, 4 reviews
Superhost
Resort in Myrtle Beach
Harbour Lights- 2 bedrooms
New place to stay
Hostel in Charleston
The Goldman Room @ The Annex
Feb. 16 – 23
$142 CAD per night
4.71 out of 5 average rating, 371 reviews
Hotel room in Charleston
Charleston's Most Charming Historic Inn
Aug. 1 – 8
$441 CAD per night
4.66 out of 5 average rating, 271 reviews
Resort in Myrtle Beach
Oceanfront 2 Bedroom-Sandy Beach 1612 - Sleeps 8!
Aug. 5 – 12
$939 CAD per night
4.43 out of 5 average rating, 49 reviews
Hotel in Myrtle Beach
Serendipity King Room w/ Kitchen
Apr. 14 – 21
$198 CAD per night
4.5 out of 5 average rating, 4 reviews
Hotel in North Charleston
Apartment Style Living
Aug. 5 – 12
$124 CAD per night
New place to stay

Hotels with a pool

Guest favourite
Boutique hotel in Murrells Inlet
The Inlet Cottage Guests Suite
Jan. 18 – 25
$108 CAD per night
4.96 out of 5 average rating, 114 reviews
Guest favourite
Resort in Myrtle Beach
Full condo with a million dollar view of the ocean
Oct. 14 – 21
$141 CAD per night
4.87 out of 5 average rating, 61 reviews
Superhost
Hotel in Myrtle Beach
Ocean View Suite w. Rooftop Pool
Jan. 9 – 16
$180 CAD per night
4.76 out of 5 average rating, 17 reviews
Guest favourite
Resort in Myrtle Beach
Beachfront condo ! Ocean Front !
Apr. 19 – 26
$201 CAD per night
4.93 out of 5 average rating, 29 reviews
Guest favourite
Resort in Myrtle Beach
Beautiful Ocean front Unit.
Oct. 10 – 17
$192 CAD per night
4.88 out of 5 average rating, 65 reviews
Guest favourite
Resort in Myrtle Beach
Ocean view condo @ The Palace
Apr. 26 – May 3
$217 CAD per night
4.79 out of 5 average rating, 29 reviews
Superhost
Resort in Myrtle Beach
Charming condo in Landmark hotel-Sleeps 4
Jan. 27 – Feb. 3
$134 CAD per night
4.76 out of 5 average rating, 67 reviews
Guest favourite
Resort in Myrtle Beach
Amazing Ocean views! Pool, lazy river, hot tub
Apr. 12 – 19
$318 CAD per night
5.0 out of 5 average rating, 20 reviews
Superhost
Resort in Myrtle Beach
Oceanfront Resort with a View - Freshly Renovated
Jul. 5 – 12
$367 CAD per night
4.63 out of 5 average rating, 38 reviews
Superhost
Resort in North Myrtle Beach
Tilghman Beach and Golf Resort 3 bed, 3 full bath
Feb. 17 – 24
$370 CAD per night
4.86 out of 5 average rating, 49 reviews
Guest favourite
Resort in Myrtle Beach
Beach Hideaway - Grande Cayman Resort MB *King bed
Jan. 13 – 20
$204 CAD per night
5.0 out of 5 average rating, 17 reviews
Guest favourite
Resort in Myrtle Beach
Beautiful 2 bedroom resort at Myrtle Beach
Jan. 12 – 19
$851 CAD per night
5.0 out of 5 average rating, 11 reviews

Hotels with a patio

Hotel room in Travelers Rest
Trailside Wedge
Apr. 22 – 29
$378 CAD per night
New place to stay
Superhost
Boutique hotel in Sunset
"Muskrat" room at Wilderness Retreat Center
Mar. 18 – 25
$74 CAD per night
4.56 out of 5 average rating, 9 reviews
Guest favourite
Room in Spartanburg
Lovely 1 br/1 private bath.
Jan. 19 – 26
$117 CAD per night
4.95 out of 5 average rating, 22 reviews
Guest favourite
Resort in Myrtle Beach
2bd 2ba ocean view condo
Jun. 22 – 29
$526 CAD per night
4.92 out of 5 average rating, 26 reviews
Superhost
Hotel in Hilton Head Island
Oceanfront suite at Surf Watch
New place to stay
Superhost
Hotel in North Myrtle Beach
2 BDR condo @ Ocean BLVD Wyndham
New place to stay
Superhost
Hotel in North Myrtle Beach
Westwinds Resort - 2BR Unit
Feb. 4 – 11
$380 CAD per night
New place to stay
Superhost
Hotel in Myrtle Beach
Sheraton Broadway Resort - 2BD
May 14 – 21
$505 CAD per night
New place to stay
Superhost
Hotel in Myrtle Beach
2 BR @ Ocean Watch Grand Dunnes
Jul. 13 – 20
$1,276 CAD per night
New place to stay
Guest favourite
Hotel in North Myrtle Beach
1 bedroom King bed North MB 441
Feb. 18 – 25
$112 CAD per night
5.0 out of 5 average rating, 9 reviews
Resort in Pawleys Island
Bubbles Up at Litchfield By The Sea
Sep. 5 – 12
$162 CAD per night
4.75 out of 5 average rating, 4 reviews
Resort in Myrtle Beach
Oceanfront Family Suite
Oct. 9 – 16
$214 CAD per night
4.76 out of 5 average rating, 25 reviews

Destinations to explore