
Vacation home accommodations in South Carolina
Find and book unique vacation houses on Airbnb
Top-rated vacation houses in South Carolina
Guests agree: these vacation houses are highly rated for location, cleanliness, and more.

Secluded Treehouse Overlooking Saltwater Marsh
Relax, decompress, and unwind up in the trees at the edge of the Atlantic in our secluded Treehouse overlooking the saltwater marsh. Panoramic floor to ceiling windows wrap around the entirety of this unique treehouse. 2 Bedroom 2 Bathroom Treehouse with 3 decks. Watch the sunrise from the comfort of the couch, nap in the comfy rope hammock, or take a cruise in the brand new golf cart included with your stay. Just a short 5 min golf cart ride to the beach. Secluded paradise is waiting for you

City Dream Spacious 2BR/2BA Walk the Heart of GVL
Enjoy a last minute city escape to GVL! Enjoy 2 FULL BATHROOMS. Prime location by Main St. to walk,trolley,bike downtown or to trail. This gem is 5 min walk to Bcycle/trolley @Fluor Field.12 min walk to Falls.Uber friendly.See shops-art galleries-museums-tours-eateries-breweries-outdoor activities.Newly remodeled spacious historic bldg w 10’ ceilings, wood floors & new baths.1300 sq.ft entire 1st floor.1 King &1 Queen bed.Large private patio,full kitchen/living/dining. Games & records.PARK FREE

The Parlor #1
After family used this unit for several years, we are back in Airbnb mode as of 12/25! Updated pics coming soon! Come relax and enjoy life in the country! Our apartment is an actual renovated milking parlor! While the dairy is no longer in operation, we have beef cattle that you may see as you sit and enjoy your coffee on the front porch! There is a one queen bed but we are ok with a couple children on floor beds or couches. Just ask! We are 6 minutes from Abbeville and 12 minutes from Due We

Patriot Point B, an inviting studio apartment
This patriot themed studio apartment sleeps 5. The apartment includes a queen, pull out queen sofa bed, optional roll out full bed, a full kitchen, 1 bathroom, full laundry area, with areas for relaxing, bonfire and a gas grill. The apartment offers cozy patriotic decor including several historic homes in the area. It's charming and includes a large room with designated areas for the bed and living area, a kitchen and separate bath. We are minutes from downtown Spartanburg. Kerri & Brian

Lake House and Dock Upscale and Immaculate
Our immaculate 2020 built water-themed home is a luxury furnished lakefront 1.1 acre property on Lake Hartwell with a large boat dock. Our house enjoys amazing lake views and is perfect for the tournament fisherman, the boating enthusiast, golfers, families and those just needing to relax. We are down the street from Stonecreek Cove Golf Course in a countryside atmosphere and are comfortably close to the renowned Green Pond Landing, host to many national fishing tournaments.

Oceanfront Balcony Penthouse @ Myrtle Beach Resort
Oceanfront penthouse (top floor) in Myrtle Beach Resort. Sleeps 7+infant (pack-n-play), 6 pools (oceanfront, indoor, 4 outdoor, some closed for winter), splash park, 6 hot tubs, pickleball, basketball, tennis, cornhole, volley ball, general store/snack shop, steamrooms, saunas, fitness centers, playground, onsite laundry, beach bar, gated entrance, free cable, private high-speed Internet, keyless entry, 8 min to airport and golf, 15 min to Broadway, tons of attractions!

Cozy House - Just a Short Walk to the Beach!
Relax with the whole family at this peaceful house located only a few blocks away from the beach with mini golf course in its back yard. Take an early morning walk to enjoy the sunrise over the ocean. The house is freshly painted with the gated pool across the street. Located a walking distance away from one of the most unique & popular shopping, dining & entertainment destinations Barefoot Landing as well as one of the biggest attractions Alligator Adventure.

Lakefront Paradise W/Pool/hot tub/outdoor kitchen
Brand new heated saltwater pool, hot tub and outdoor kitchen area. This upgraded home is ready to host your family or large group! Enjoy breathtaking sunsets year round from your private beach directly on the big waters of Lake Marion. Spends evenings out on the dock fishing or pull your boat right up to the beach. Ping pong and bumper pool tables, fast wifi and big screen tv's make for the perfect entertaining space for large groups.

Hippie Hideaway-The Betsy awaits your arrival.
Just steps away from the beach, The Betsy Surf shack is a unique beach home in Windy hill. Windy hill is a quaint little hideaway in North Myrtle Beach. Our home has a lovely front porch for reading and relaxing. This home hosts two bedrooms and is pet friendly. Our back yard has a large area to enjoy sitting at the picnic table or by the fire pit. If you need a getaway with a sweet home near the beach. The Betsy Surf shack is waiting.

Pirate Oak Bunkhouse
Bunkhouse with large deck under a Live Oak in Murrells Inlet. Small manufactured home with two bedrooms, full bath and furnished kitchen. There is room to bring your pop-up camper or tent and enjoy the large lot with a camp fire pit to create family memories. Wacca Wache Marina on the Intercoastal Waterway is ten minutes away, enjoy the Marshwalk in Murrells Inlet just 3.5 miles away and we are located 15 miles south of Myrtle Beach.

Peaceful, Pet-Friendly Treehouse w/Bikes included
Escape to our unique, pet-friendly waterfront treehouse on Seabrook Island! This updated 2-bed, 2-bath retreat offers serene lagoon views and a swing bed at the water's edge. Surrounded by nature, it's perfect for a relaxing getaway. Enjoy a short walk to the beach, community pool, and gym. Ideal for small groups or families seeking a tranquil island experience. Your private, elevated nature retreat awaits!

Downtown 4BR + Backyard Oasis | 2 Parking Spots
Experience Charleston in style at this brand-new 4BR/3BA retreat on Spring Street! Perfect for groups with a rare downtown perk: 2 dedicated parking spots plus a private outdoor lounge. Enjoy bright, modern interiors, a spacious kitchen & dining setup, and walkable access to King Street dining, nightlife, shopping, and historic Charleston charm.
Popular amenities for South Carolina vacation houses
Family-friendly vacation houses

Cozy Lake Hartwell Home 25 Minutes from Clemson

Ocean Palms Villa @Westin with Amenities included!

Clemson/Anderson Lake Hartwell

Oceanfront, 50 yds from the beach and pool

Cheerful two bedroom home 1 1/2 miles from beach.

Resort Studio for July 4th Fireworks

Cozy Designer Home in Downtown Aiken, Walkable!

Luxury 4 Bdr Beachfront in Hilton Head- DC Breeze
Vacation home rentals with a patio

Studio in the heart of Greenville

Cozy-Modern Retreat with outdoor entertainment

Charleston Meets Paris Villa!

The Two Buoys. Steps to the Beach and Local shops!

4BR/ 3BA Oceanview Home in Ocean Lakes

1 Bedroom Ocean Villa Hilton Head

Cyprus Inn - Hot Tub - Pool - Walk to Beach

Surfside-Garden City Beach With Golf Cart
Vacation home rentals with a washer and dryer

Pet friendly beach cottage

Lakefront Hartwell Home w/NEW Dock + NEW Fire Pit

Walking distance to stadium with 4 parking spots!

Getaway house in a Golf Community

Beach Getaway

Coastal compound by the beach | 3 units all yours

The Byrd House

Golfer's Paradise Beachaholic North Myrtle Beach
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