Lake house vacation rentals in South Carolina
Find and book unique lake houses on Airbnb
Top-rated lake house rentals in South Carolina
Guests agree: these lake houses are highly rated for location, cleanliness, and more.
Vacation rentals for every style
Get the amount of space that is right for you.
Popular amenities for South Carolina lake house rentals
Waterfront lake house rentals
Home in Summerton
5 out of 5 average rating, 95 reviewsCheerful 3 bedroom home on the lake
Home in Chapin
4.94 out of 5 average rating, 82 reviewsLake Murray: Panoramic Views, Kayaks & Hot Tub
Home in Seneca
4.99 out of 5 average rating, 185 reviewsLakeside @ Lake Hartwell in Clemson, SC 🐟🌅🚤
Home in Chapin
5 out of 5 average rating, 8 reviewsFamily Ties Lakeside Retreat
Home in Pawleys Island
4.95 out of 5 average rating, 148 reviewsPawleys Island Family Retreat for any Season
Home in Summerton
4.9 out of 5 average rating, 39 reviewsThe Pointe at Goat Island W/Pool, boat ramp & Pier
Home in Camden
5 out of 5 average rating, 22 reviewsBig Water Sunset at Lake it Easy
Home in Irmo
4.87 out of 5 average rating, 104 reviewsLakefront w pool, dock and pool table, sleeps12
Pet-friendly lake house rentals
Home in Cross Hill
4.95 out of 5 average rating, 21 reviewsBlue Anchors.
Home in Anderson
4.96 out of 5 average rating, 82 reviewsSunset Point-Best view on Broadway - HOT TUB!
Home in Anderson
4.99 out of 5 average rating, 190 reviewsLake Escape
Home in Easley
4.91 out of 5 average rating, 144 reviewsLarge lake house - 15 min to Downtown Greenville
Home in Modoc
4.93 out of 5 average rating, 109 reviewsIvy’s Escape (water front) at Lake Thurmond
Home in Bluffton
4.98 out of 5 average rating, 147 reviewsOld Town Bluffton Cottage + FREE Golf Cart!
Home in Waterloo
4.98 out of 5 average rating, 81 reviewsLakefront Home with Hot Tub! Kayaks,SUP's,Fireplace! King beds, PingPong, CornHole!
Home in Hilton Head Island
4.87 out of 5 average rating, 115 reviewsBlue Sky Villa: Beach/pets/golf/tennis/pickleball
Private lake house rentals
Home in Gilbert
5 out of 5 average rating, 13 reviewsTranquility
Home in Ninety Six
5 out of 5 average rating, 41 reviewsLakefront Retreat
Home in Moncks Corner
4.84 out of 5 average rating, 45 reviewsCozy Little Nook
Home in Seneca
4.85 out of 5 average rating, 13 reviewsCozy Clemson Lake Getaway with Dock Access
Home in Cross Hill
5 out of 5 average rating, 28 reviewsKristen's Lakeside Retreat with hot tub!
Home in Eutawville
5 out of 5 average rating, 18 reviewsQuiet, Private lake front home, kayaking/fishing
Home in Lexington
5 out of 5 average rating, 18 reviewsSunrise and Sunset on the Lake
Home in Eutawville
4.94 out of 5 average rating, 52 reviewsHeated Indoor Pool/Lake Front and Dock
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