We’re sorry, some parts of the Airbnb website don’t work properly without JavaScript enabled.

Some info has been automatically translated. Show original language

Airbnb your place

House vacation rentals in Panama

Find and book unique houses on Airbnb

Top-rated house rentals in Panama

Guests agree: these houses are highly rated for location, cleanliness, and more.

0 of 0 items showing

1 of 3 pages

Home in Bocas del Toro

4.85 out of 5 average rating, 136 reviews

Architectural Waterfront Home- "Casa Sur"

As seen on the leading modern architecture site, Dwell! Casa Sur is half of Casa Comunal, a rustic home on the Caribbean beachfront. It shares a roof & entryway room w/ Casa Norte, our other listing, but separated by 2 sliding walls for total privacy. Lush gardens, fruit bearing trees, designed for surfers, snorkelers, yogis, with a massive deck & private sand beach. Mid-Century interior designs handcrafted by local artisans, stunning textiles, a sustainable rainwater catchment system & more.

Guest favourite

Home in Costa Esmeralda

4.97 out of 5 average rating, 127 reviews

Beach House-Amazing Pool, Surf & Pet Friendly

Majestic Sands! Come relax with the whole family at this piece of paradise. Majestic Sands is located in a private beach community in Costa Esmeralda, San Carlos District, Panama. It is located a few minutes from the Pan-American highway and a few minutes from other local beaches such as Gorgona, Santa Clara and Coronado. It is a 5-minute walk to our beach, or if you prefer you can go by car. The home includes an amazing saltwater pool and hot tub with hammocks with views of amazing palm trees.

Home in Bastimentos

4.81 out of 5 average rating, 105 reviews

Spacious, Over the Water Home with Plunge Pool

Perched over the water in Bastimentos Bay, this well-appointed four bedroom and three bath single family home combines classic Caribbean architecture with modern sensabilities. With over 2,000 sq ft of comfortably furnished spaces, there’s room enough for eight adults to spend time together - or apart - in any weather. BBQ poolside, stargaze from the hammocks, fish off the dock, walk to grab a drink, or flag down a water taxi from your private boat dock for the ten minute trip to Bocastown.

Guest favourite

Home in Los Algarrobos

4.99 out of 5 average rating, 133 reviews

New house! 5 min from David on the Boquete highway

It’s a new house (Oct 2019) just outside David in Los Algarrobos. Close to the airport, Boquete, Volcan and only 3.5km from the huge new Federal Mall in David. Evening security guards in the subdivision all year. Mountain views, covered parking, seconds from the boquete highway. This immaculate house has all new appliances and furniture, 5G internet, cable tv and Netflix. Your bilingual hosts live next door, the co-host (Grethel) is Panamanian, a lawyer and knows everything about Panama.

Guest favourite

Home in Pedasí

4.95 out of 5 average rating, 141 reviews

3 min to Pedasi, 5 min to the Beach, Private Pool!

Your family will be close to everything when you stay at this centrally-located place. Outfitted with room to sleep 6 and a fenced yard for your dog, Casa Catch and Relax has it all! Look us up online, Casa Catch and Relax You'll Love - Beach access a short drive or walk away (3 min drive, 10 min walk) - Central to town and local restaurants - Private, fenced outdoor space with pool - Cool days and nights with A/C in every room - Fully equipped kitchen and tons of sleeping space - Wifi

Guest favourite

Home in Los Algarrobos

4.97 out of 5 average rating, 106 reviews

Cozy and relaxing house with terrace

Relax with the whole family in this quiet place, 10 minutes from the center of David and 25 minutes from the tourist Boquete, very close to shopping centers, restaurants, but away from the hustle and bustle of the city. Very safe place and full of amenities. The house has three bedrooms, 2 bathrooms, a living room, a dining room, a fully equipped kitchen and a beautiful terrace with TV, piano, a bar among other amenities. All spaces have aires conditioned, hot water and TV with 222 channels.

Guest favourite

Home in Bocas del Toro District

4.92 out of 5 average rating, 208 reviews

Orange House - Over The Water Rentals

Enjoy golden sunsets across the bay from the Orange House at Over The Water Rentals. Home away from home in a tropical paradise. Relax on your outdoor lounge or explore the bay. The house has snorkel gear, SUP's & kayaks for guests to use for free. Located close to town & airport in a quiet local neighborhood. The house features a king size master bedroom & queen guest room, spacious hot water shower, handmade organic toiletries, fully equipped kitchen & high speed wifi

Guest favourite

Home in Taboga Island

4.97 out of 5 average rating, 156 reviews

Casa Rosie - Dream Home on Tabogá Island

Casa Rosie is a gorgeous villa on Taboga island with an intimate vibe and spectacular views of the ocean. The perfect place for couples, small groups, and families to unwind and make magical memories! . With great wifi, fully equipped kitchen, 3 inviting bedrooms, and a spacious yet personal feel… Casa Rosie is your home away from home. Included in every stay is free pick up and drop off to the ferry terminal - please let us know the details of your arrival.

Home in Vista Mar Golf, Beach & Marina

4.88 out of 5 average rating, 234 reviews

Luxurious Beach House - Private Pool Golf & Marina

Vista Mar Golf, Beach & Marina is a gated community with private security, with direct access to a state of the art golf course designed by J. Michael Poellot. It also has marina, heliport, tennis courts, direct private beach access, bars and restaurants. The house comes with an outdoor private pool & hot tub, also a amazing private outdoor kitchen, and an amazing sea view with spectacular sunrises and sunsets. any inquiry please contact 66168596

Guest favourite

Home in Las Colinas de Caceres de Arraijan

4.98 out of 5 average rating, 198 reviews

Tropical Haven with Yoga Platform

Tropical "open-concept" Airbnb, with a private pool and yoga/meditation platform, located in a typical village, 20 minutes outside the hustle of Panama City, Panama - Central America. This modern contemporary tropical home is located in the hills of Caceres on a 5 acre finca full of tropical trees, birds, and a manicured grounds. Outdoor gas and charcoal barbecue off of back patio with vertical herb garden for perfect relaxation retreat.

Guest favourite

Home in Río Hato

4.98 out of 5 average rating, 111 reviews

Renewed / Make yourself at Home / Enjoy

Cozy & comfy villa with great illumination and natural ventilation located in the Playa Blanca Beach & Lagoon complex in Rio Hato, Cocle just 10 minutes away from Scarlett Martinez International Airport and 90 minutes from Panama City. Playa Blanca is an exclusive tourist residential beach complex with villas, apartments, big lush green areas, the largest pool in Central America, beach club, Playa Blanca Hotel Resort and much more.

Guest favourite

Home in El Valle de Antón

4.94 out of 5 average rating, 131 reviews

Rustic family mountain home - 5 min walk to town!

Rustic family home with exquisitely landscaped garden complete with bridge over natural stream. Outdoor chill out space with barbecue and terrace under roof with hammocks on one side of the house, and a pergola with lounge area and gas grill on opposite side of the house. Centrally located to main attractions, only a 7 minute walk to the main market. Peaceful, relaxing refuge surrounded by views of nature and the cloud forest.

Vacation rentals for every style

Get the amount of space that is right for you.

Chalets

Adventure-ready homes with après-ski style

Cottages

Quaint homes, peaceful surroundings

Apartments

Convenient locations with everyday essentials

Popular amenities for Panama house rentals

Free parking on premises

Air conditioning

House rentals with a pool

Guest favourite

Home in Panama

4.96 out of 5 average rating, 140 reviews

Villa Isabella in Coronado Beach Panama

Home in Provincia de Panamá Oeste

4.84 out of 5 average rating, 25 reviews

Luxurious beach front home in Veracruz

Guest favourite

Home in Bocas Del Toro

4.96 out of 5 average rating, 97 reviews

Wiona of Villa Paraiso | Beachfront Villa & Pool

Guest favourite

Home in Playa Venao

5 out of 5 average rating, 16 reviews

Nearly Oceanfront: Blue 3 Bedroom Spacious Villa

Guest favourite

Home in Playa Hermosa

5 out of 5 average rating, 27 reviews

Entire house with private pool facing beach !

Guest favourite

Home in Bocas del Toro Province

5 out of 5 average rating, 24 reviews

The Pool House, Beach House on Paunch Beach

Guest favourite

Home in Río Hato

4.96 out of 5 average rating, 25 reviews

Villa Santorini | Playa Blanca

Guest favourite

Home in Playa Coronado

5 out of 5 average rating, 13 reviews

The Dream of Playa Coronado

Weekly house rentals

Guest favourite

Home in Bajo Boquete

4.99 out of 5 average rating, 67 reviews

Beautiful new house in Boquete

Guest favourite

Home in Santa Catalina

4.95 out of 5 average rating, 41 reviews

Casa Colibrí - modern house in the green

Home in Gamboa

4.87 out of 5 average rating, 91 reviews

BirdHouse@ Gamboa Panamá Canal

Guest favourite

Home in Isla Carenero

5 out of 5 average rating, 14 reviews

Casa Blanca-Sea Views/outdoor living/walk to surf

Guest favourite

Home in Bastimento

4.85 out of 5 average rating, 47 reviews

Bay Of The Floating Palms - Beach Front Home

Guest favourite

Home in Bocas del Toro

5 out of 5 average rating, 19 reviews

Open Living, Lush Garden, 3 Min to Beach, AC&TV

Guest favourite

Home in Bocas del Toro

5 out of 5 average rating, 32 reviews

Tropical Paradise, Oceanfront Home in the Jungle

Guest favourite

Home in Jaramillo Arriba

5 out of 5 average rating, 13 reviews

House in Boquete w/ King Beds, A/C & Hot Tub

Private house rentals

Guest favourite

Home in Altos del Maria

5 out of 5 average rating, 24 reviews

Portazul - A Mountain Retreat

Guest favourite

Home in Punta Chame

4.89 out of 5 average rating, 9 reviews

Casa Divi Divi Punta Chame

Guest favourite

Home in Río Hato

4.88 out of 5 average rating, 75 reviews

Poolside Paradise in Santa Clara

Home in Panama City

4.86 out of 5 average rating, 14 reviews

Casa AcoModo @Casco Viejo (4Bdr Historic Mansion)

Guest favourite

Home in Torio

5 out of 5 average rating, 14 reviews

Ideal Creative Retreat Immersed in Forest

Guest favourite

Home in Santa Catalina

5 out of 5 average rating, 17 reviews

Casa Tropical- Private Home in Santa Catalina

Guest favourite

Home in Jaramillo

4.92 out of 5 average rating, 13 reviews

Castle in the Sky

Guest favourite

Home in Santa Fe

4.94 out of 5 average rating, 17 reviews

Santa Fe House with an amazing view

Destinations to explore