
Guesthouse vacation rentals in Mount Pleasant
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Top-rated guesthouses in Mount Pleasant
Guests agree: these guesthouses are highly rated for location, cleanliness, and more.
Vacation rentals for every style
Get the amount of space that is right for you.
Popular amenities for Mount Pleasant guesthouses
Family-friendly guesthouses

Salt of the Island Retreat w/ Pool on the Lake

Cozy Cottage w Games, Firepit, Grill, and More!

Riverland Terrace Guesthouse

Charming Charleston StudioOne!

Cottage apartment near beach and downtown

Creekside Cottage (Tiny Home)

Private waterfront apt in the oaks

Urban Oasis, West of the Ashley
Guesthouses with a patio

Quaint Cottage Studio in Ashley Forest (Avondale).

Farm Stay w Gardens, Cute Animals, Firepit + Porch

Spacious 1 bedroom cottage in Avondale

Driftwood Cottage

My Happy Place

The Violet Villa w/no cleaning fee

The James: “Tiny” Home b/w Downtown & Folly

5 Star Private Guest House • Heart of Park Circle
Guesthouse rentals with a washer and dryer

Island Oasis Hideaway | Easy Beach & City Access

Cozy Apartment in Mount Pleasant

Private Coastal Cottage-Near Beaches & Charleston!

James Island "La Casita" Nestled btw Beach & City

Cozy Park Circle, Charleston Guest House

Charming Guest Cottage in Old Mount Pleasant, SC

Serene Location - Next to Hampton Park: Haven Hom

The Guesthouse at Old Orchard
Quick stats about guesthouse rentals in Mount Pleasant
Total rentals
50 properties
Total number of reviews
6.6K reviews
Family-friendly rentals
10 properties are a good fit for families
Pet-friendly rentals
10 properties allow pets
Rentals with dedicated workspaces
20 properties have a dedicated workspace
Wifi availability
50 properties include access to wifi
Destinations to explore
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- Rentals with outdoor seating Mount Pleasant
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- Rentals with beach access Mount Pleasant
- Guesthouse rentals Charleston County
- Guesthouse rentals South Carolina
- Guesthouse rentals United States
- Park Circle
- Hunting Island State Park Beach
- Sullivan's Island Beach
- Bulls Island
- Middleton Place
- The Golf Club at Wescott Plantation
- James Island County Park
- Waterfront Park
- Shem Creek Park
- Harbor Island Beach
- Hampton Park
- The Charleston Museum
- Angel Oak Tree
- Driftwood Beach
- Isle of Palms Beach
- Morris Island Lighthouse
- Hunting Island Beach
- Seabrook Island Beach
- The Beach Club
- Charleston Aqua Park
- White Point Garden
- Seabrook Beach
- Whirlin' Waters Adventure Waterpark
- Gibbes Museum of Art
- Things to do Mount Pleasant
- Nature and outdoors Mount Pleasant
- Things to do Charleston County
- Tours Charleston County
- Food and drink Charleston County
- Nature and outdoors Charleston County
- Sports activities Charleston County
- Art and culture Charleston County
- Sightseeing Charleston County
- Things to do South Carolina
- Sports activities South Carolina
- Sightseeing South Carolina
- Art and culture South Carolina
- Food and drink South Carolina
- Entertainment South Carolina
- Wellness South Carolina
- Nature and outdoors South Carolina
- Tours South Carolina
- Things to do United States
- Tours United States
- Nature and outdoors United States
- Sightseeing United States
- Art and culture United States
- Food and drink United States
- Wellness United States
- Entertainment United States
- Sports activities United States