Guesthouse vacation rentals in Mount Pleasant

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Top-rated guesthouses in Mount Pleasant

Guests agree: these guesthouses are highly rated for location, cleanliness, and more.

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Guest favourite

Guesthouse in Mount Pleasant

4.97 out of 5 average rating, 222 reviews

Cozy Apartment in Mount Pleasant

Our place is a cozy and bright garage apartment. It has one bedroom, living room with sleeper sofa, a full bath with tub and fully equipped kitchen. We hope this provides that home away from home feel in a relaxed, yet inviting setting. It is close to dining, the beach and a ten minute ride across the bridge to Charleston. You’ll love our place because of the coziness and the location. Our place is good for couples, solo adventurers, and business travelers. STRPermit# ST240232 SCBUSLIC#20122393

Mar. 12 – 19

$227 CAD per night

Guest favourite

Guesthouse in Mount Pleasant

4.98 out of 5 average rating, 258 reviews

#1 SC AIRBNB IN MT. PLEASANT OLD VILLAGE. BEACHES!

#1 VOTED by AirBnB '21/'23! Newly built in 2018 fully furnished apartment. 700 sq ft one br w/Queen bed & walk-in closet. Spacious Living rm w/full size Futon. One bath w/shower & tub. Washer & dryer, full kitchen w/ stainless steel appliances. Modern amenities, WIFI, Netflix, all soaps, hair dryer, iron, luggage stands & a whole lot more. Private drive up parking! Our place in the Old Village is within stone's throw to Folly Beach, Downtown Charleston, and Sullivan's Island/Isle of Palms.

Jul. 16 – 23

$287 CAD per night

Guest favourite

Guesthouse in Mount Pleasant

4.98 out of 5 average rating, 181 reviews

Charleston Guest House

Conveniently nestled in the heart of Mt. Pleasant and only a short car ride from the best that Charleston has to offer. Minutes away from historic sites such as Boone Hall Plantation, Palmetto Island County Park, Belle Hall shopping center and many other attractions. Centrally located between Isle of Palms/Sullivan's beaches and downtown Charleston. Located in a peaceful, family friendly community reminiscent of old country living. Sit back and enjoy the quietness of your home away from home.

Aug. 28 – Sep. 4

$319 CAD per night

Guest favourite

Guesthouse in Mount Pleasant

4.99 out of 5 average rating, 248 reviews

Upscale Couple's Escape | Beach & Downtown CHS

Perfect getaway for anyone looking to relax and enjoy the beautiful Charleston beaches. We maintain the highest standards for luxury - including curated interior design touches to make you forget reality and enjoy some much needed R&R time. The Pump House is the ideal place to escape to and enjoy the outdoors, local restaurants, breweries, parks, and, of course, beaches! Our reviews speak for themselves - Always 5 stars and many return guests! Permit #ST230013 | Business License #20103454

Jul. 5 – 12

$443 CAD per night

Guest favourite

Guesthouse in Mount Pleasant

4.98 out of 5 average rating, 436 reviews

Old Mt. Pleasant/Shem Creek close to Sullivans/DT

This 1 bed/1 bath bungalow sits among the Old Mt. Pleasant neighborhood off Coleman Blvd, which is only 3 mi. to Sullivans Island Beach, <1 mi. to Shem Creek! A quick ride will land you in bustling downtown Charleston. Walk or Bike to the stunning Pitt St Bridge and watch the sunset. Walk popular Coleman Blvd which boasts restaurants, shops, boutiques and fitness venues alike, only 1 block away. 3 grocery stores <1 mi. Quiet, clean, and quaint! STR Permit #ST230005 MP Bus Lic #20115373

Nov. 2 – 9

$323 CAD per night

Guest favourite

Guesthouse in Mount Pleasant

4.99 out of 5 average rating, 299 reviews

Ocean Inspired Village Hideaway Old MP

STR PERMIT # ST240238 BUS. LIC.# 20123492 Kick back on a sofa in a light blue living room amid oceanic coastal decor. This gem is only 3 miles from Sullivans Island beach and 7 miles to downtown Charleston. After a day at the beach, take a stroll down to the Pitt Street bridge and watch a beautiful sunset on the water. Come experience this cute coastal cottage escape, tucked away in Old Mount Pleasant. One of the oldest and most charming neighborhoods east of the cooper.

Oct. 13 – 20

$498 CAD per night

Guest favourite

Guesthouse in Mount Pleasant

4.98 out of 5 average rating, 214 reviews

Bungalow Under The Oaks

Small guest house in the heart of Mount Pleasant! Ideally located to both Isle of Palms and Sullivan's Island beaches (both 7 minutes) and only 15 minutes to the heart of historic downtown Charleston. Our private guest bungalow is a perfect launching spot for all your exploring. End the day relaxing under the shade of our mature live oak. The house has its own entrance and separate yard that is fully fenced in. LHR Permit: ZSTR-02-21-00318, License: LIC-3-21-252314.

Sep. 21 – 28

$260 CAD per night

Guest favourite

Guesthouse in Charleston

4.97 out of 5 average rating, 334 reviews

Daniel Island Getaway

Welcome to your home away from home near Center Park on Daniel Island, located within 20 minutes from Downtown Charleston, Sullivan’s Island and Isle of Palms. This almost 600sqft above garage guest house has a separate bedroom and full bathroom in addition to a spacious living room with a Queen sofa bed and a kitchen area that will meet all of your basic needs. The kitchen includes a Keurig, microwave and griddle. There is even an outdoor shower for guests to use.

Jan. 14 – 21

$236 CAD per night

Guest favourite

Guesthouse in Mount Pleasant

4.98 out of 5 average rating, 116 reviews

Beach, downtown, Alhambra Hall weddings so close!

Quiet location close to everything Charleston has to offer! Located in historic Old Village we are less than 2 blocks from Alhambra hall (with playground) and 10 minutes walking to Pitt street bridge recreational area. Sullivan's Island beach is 3 miles away, with a bike path or sidewalk the entire way! After a day of exploring, relax for a few then go downtown Charleston (10 minutes away) or to the Shem Creek district (minutes away)! Cable/Wi-Fi are provided.

Aug. 25 – Sep. 1

$274 CAD per night

Guest favourite

Guesthouse in North Charleston

4.93 out of 5 average rating, 723 reviews

Boho Converted Garage Apt. - Cozy & Convenient!

Stay in centrally located Park Circle for a charming Charleston experience you won't get downtown! * 1-2 minute walk to Park Circle restaurants and bars * 10-minute drive from the Charleston International Airport * 10-20 minute drive to Historic Downtown Charleston * 30-minute drive to local beaches - Drives times are assuming traffic isn't awful! It can get bad during peak seasons, but the point is, we are very centrally located in the Charleston area!

Aug. 12 – 19

$174 CAD per night

Guest favourite

Guesthouse in Mount Pleasant

4.97 out of 5 average rating, 407 reviews

Guesthouse Convenient to Charleston, Shem Creek, and Beaches

Relax in this separate guest home nestled in a well-established Lowcountry neighborhood. The ‘treehouse’ has an open-plan design with vaulted notched board ceilings, creating a feeling of light and space, with elegant furnishings throughout. The well-equipped kitchen and grill on the porch encourages intimate home cooking. We lived in this space before we moved into the main house, so we can attest to it being comfortable, and well maintained.

Feb. 1 – 8

$269 CAD per night

Guest favourite

Guesthouse in Mount Pleasant

4.95 out of 5 average rating, 220 reviews

Green Garden Studio @greengardenstudio2017

Studio apartment with a king bed, full pull out couch, and kitchen. Kitchen has fridge, microwave, skillet, and toaster oven. Set back from the house. Privacy. Very quiet neighborhood. We provide sheets and towels for the apartment but we do not have towels for the beach. Check us out at @greengardenstudio2017 Mount Pleasant STR Permit # ST240273 and BL# 20123435

Sep. 18 – 25

$197 CAD per night