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Hotel vacation rentals in Panama City

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Popular amenities for Panama City hotels

Family-friendly hotels

Hotel room in isla contadora.
4.75 out of 5 average rating, 8 reviews

Beautiful B&B with unbeatable customer care!!!

Alma RosaRating, 5 stars37 months ago
The beach is very close by walking, but in the heat it is difficult to walk long distances. It is considerable to rent a cart early to ensure availability
Private room in Punta Chame
4.8 out of 5 average rating, 51 reviews

Tanti 2, room in house on beachfront terrain

CatherineRating, 5 stars27 months ago
I highly recommend you to spend your vacation there. Francisco is an extraordinary welcome! We have dinner with him and his family. People with a big heart!! The beach and on-site facilities are worth a visit. The only negative point ( said with lots of love ) is that when booking we can't choose the room and the number of people. I could just book for one person. I was told that there would be an extra charge for the 2nd person. (my friend) At the end of my stay, I was charged double the price. I admit to being surprised and paying 2 x the price to be 2 in the room instead of one person. I may have had to inquire about the extra price when booking because it changes a hotel room budget… All of you, Francisco, and the people who work for him, of exceptional kindness:)
Superhost
Private room in Taboga Island
4.69 out of 5 average rating, 51 reviews

Eco Lodge Garden Room 4, Oceanview Plunge Pool

ScottRating, 5 stars3 months ago
way better than described. authentic island feel, covered hammock area, literally against the jungle.beautiful
Hotel room in Punta Chame
5 out of 5 average rating, 9 reviews

Pink Palace Panama

AlejandroRating, 5 stars10 months ago
Great experience at Peggy's place, a top-notch hostess! Sweet, attentive and very helpful. Important that they know that they have 3 dogs, they are very friendly. The house is facing the sea, just steps walking to the shore.
Private room in Panamá
4.33 out of 5 average rating, 3 reviews

Private Room #4. 3 people

RobertoRating, 5 stars25 months ago
Comfortable place and quite focused for backpackers. The photographs match the place. A good price.
Top guest favourite
Private room in Panamá
4.99 out of 5 average rating, 103 reviews

Casa Momote Loma Limon

AndreaRating, 5 stars5 days ago
A hidden gem between trees and affection We had an unforgettable weekend in this corner of peace in Panama. From the first moment, Fernando and Mariel welcomed us as if we were old friends. Their warmth, their life stories, and the love with which they have built this space are felt in every corner of the place. The nearby river, the song of the birds and the tranquility of the environment make this place a true refuge from the daily noise. But what really makes this experience special is the energy that they have sown over the years: a mixture of hospitality, simplicity and soul. More than a home, it's a human experience. We were recharged, smiling, and full heart. Thank you so much Fernando and Mariel. This will not be our last meeting.
Hotel room in PA
4.66 out of 5 average rating, 68 reviews

double room, island counter

IngridRating, 5 stars3 weeks ago
We enjoyed our stay. The staff is always welcoming and super friendly. The service and the Food is delicious. We have stayed at Geralds mutiple times and we always enjoy it!

Hotels with a pool

Hotel room in Marbella
4.68 out of 5 average rating, 65 reviews

Your second home in Panama.

MarlenRating, 5 stars2 weeks ago
The truth is that I really liked it, I recommend it and I would return the clean facilities have the option of restaurants nearby, pool, the quiet area at night you can rest well, the only thing that gave the client the option to put if they want or not the daily cleaning in the room, otherwise all excellent.
Hotel room in Veracruz
4.43 out of 5 average rating, 7 reviews

Double room in Cosy pool hotel near Veracruz beach

Sara AlmudenaRating, 5 stars13 months ago
The hotel facilities are very well, renovated and cared for and clean. Very friendly with the animals, we are very grateful for that.
Hotel room in Panamá
4.25 out of 5 average rating, 4 reviews

Jr. Suite Rm #3- Cerro Azul

CarolinaRating, 5 stars42 months ago
It was a great visit. I like how pet friendly La Semilla Ecolodge is. I hope the staff also were happy for hosting my mom, my pets, and me. It was a very relaxing experience and we loved the food! - The cook is one of the reasons I always come back :)
Hotel room in Panamá
4.44 out of 5 average rating, 18 reviews

Rainforest Suite with Breakfast! 15 min from city

RogelioRating, 5 stars13 months ago
peacefully and beautiful place...
Hotel room in El Cangrejo
4.75 out of 5 average rating, 12 reviews

Double Suite-Apartment Hotel Príncipe

DiegoRating, 5 stars25 months ago
Super attention and check-in
Hotel room in Marbella
New place to stay

In the heart of the city.

CristinaRating, 5 stars2 weeks ago
My stay at Hotel Mío in Panama City was wonderful. The place is simply unbeatable - it's incredibly located, right in front of the city's most iconic skyscrapers and buildings, offering a spectacular view. The pool on the rooftop is beautiful and perfect for relaxing. Also, breakfast is included and is delicious. The hotel itself is beautiful, modern and cozy; I would definitely always come back to stay here every time I visit Panama. I want to make a special mention to Josué, from the restaurant area, whose attention was excellent and really made my experience even better. I highly recommend this hotel!
Hotel room in Panamá
3.33 out of 5 average rating, 3 reviews

Hotel Room with one full bed

RobertoRating, 5 stars3 months ago
Excellent

Quick stats about hotel rentals in Panama City

  • Total rentals

    120 properties

  • Nightly prices starting at

    $14 CAD before taxes and fees

  • Total number of reviews

    2.8K reviews

  • Pet-friendly rentals

    20 properties allow pets

  • Rentals with a pool

    30 properties have a pool

  • Rentals with dedicated workspaces

    90 properties have a dedicated workspace

Destinations to explore

  1. Airbnb
  2. Panama
  3. Panama City
  4. Hotel rentals