
Hotel vacation rentals in Panama City
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Top-rated hotels in Panama City
Guests agree: these hotels are highly rated for location, cleanliness, and more.
Vacation rentals for every style
Get the amount of space that is right for you.
Popular amenities for Panama City hotels
Family-friendly hotels

Double Room / Room two beds

Your second home in Panama.

Room for 2 people with a private bathroom

Single Triple Family Room

Room with private bathroom in downtown Panama

El Tornillo semi-private space.

The Bridge

Entire place Sofia's B&B Hostal Boutique
Hotels with a pool

Jr. Suite Rm #3- Cerro Azul

Rainforest Suite with Breakfast! 15 min from city

Double Suite-Apartment Hotel Príncipe

Double Studio - Traveler Hostels

Excellent private room

The Canal

Tropical Tranquility - Coconut Lodge

Hacienda El Edén
Hotels with a patio

Harpy Eagle Room in Treehouse

Suite Room in the ORHO Hotel

Kakún Room 12, Cable TV, Refrigerator, Air Conditioning.

Eshel Panama Suites, Atlantic suite 04

Charming Studio w Two Double Beds

Private Twin | Shared Bathroom

La Husseyenda- Birdwatcher Haven

Charming Hotel in Casco Viejo San Felipe Jr Suite
Quick stats about hotel rentals in Panama City
Total rentals
120 properties
Nightly prices starting at
$14 CAD before taxes and fees
Total number of reviews
3.2K reviews
Family-friendly rentals
10 properties are a good fit for families
Pet-friendly rentals
20 properties allow pets
Rentals with a pool
30 properties have a pool
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- Hotel rentals Panamá Province
- Hotel rentals Panama
- Things to do Panama City
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- Art and culture Panama City
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- Things to do Panamá Province
- Tours Panamá Province
- Sports activities Panamá Province
- Nature and outdoors Panamá Province
- Food and drink Panamá Province
- Sightseeing Panamá Province
- Art and culture Panamá Province
- Things to do Panama
- Food and drink Panama
- Nature and outdoors Panama
- Tours Panama
- Sports activities Panama
- Art and culture Panama
- Sightseeing Panama