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Apartment vacation rentals in Panama City

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Top-rated apartment rentals in Panama City

Guests agree: these apartments are highly rated for location, cleanliness, and more.

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Apartment in Panamá

4.86 out of 5 average rating, 267 reviews

Casco Viejo 360° View Old Tower Penthouse

Located in one of the oldest buildings in Panama and set over 3 stories with unrivaled panoramic views over the historical Casco Viejo, the skyline of Panama City and views of the causeway, our gorgeous penthouse is the ideal space to take in the local sights, sounds, art, culture, socialize with your friends and family, or simply relax in a cozy love nest! Top speed wifi, excellent location, and fully equipped with all the home comforts, the penthouse is the perfect spot to explore Panama.

Apr. 10 – 17

$518 CAD per night

Guest favourite

Apartment in Panamá

4.9 out of 5 average rating, 360 reviews

Chic Studio in Casco Antiguo - View to Main Plaza

Located in trendy Casco Antiguo, this studio apartment is walking distance of restaurants, cafes, supermarkets, pharmacies and the overall life of Casco. The building has recently been renovated and has a beautiful view of Plaza Catedral. Note: As seen on previous comments, there used to be a bar club in the rooftop and at the bottom of the building. Good news, there are no more bars in the building and the studio has soundproof doors as Casco is an area with the best nightlife in Panama.

Oct. 7 – 14

$169 CAD per night

Guest favourite

Apartment in Panamá

5.0 out of 5 average rating, 28 reviews

Amazing experience in Casco Viejo with ocean views

Disfruta la cultura panameña desde el centro de Casco Viejo, donde conocerás la arquitectura colonial, podrás visitar los mejores restaurantes, sitios nocturnos y rooftops característicos de la zona. Apartamento tranquilo y confortable. Cuenta con una cama queen, 1.5 baños, armario, aire acondicionado, cocina equipada, comedor, sala, acceso a WiFi de 500 mbps, espacio de trabajo, balcón y comedor al aire libre. ¡Te ofrecemos todo lo que necesitas para vivir la mejor experiencia local!

Dec. 27 – Jan. 3

$180 CAD per night

Guest favourite

Apartment in Panama City

5.0 out of 5 average rating, 23 reviews

Luxury Mid-Century Apartment In Casco Viejo

Luxury mid-century one bedroom Boutiqe 72 m2 apartment. Step into the elegant, functional and comfortable place that we offer with love. The apartment located within a beautiful two-floors antique building in the heart of Casco Viejo. The apartment includes a well equipped brand new kitchen, a dining area and a spacious living room, also a balcony with a view of the lively streets below. The tranquil bedroom has an ensuite bathroom and a walking closet that fitting perfectly to your needs.

Jun. 17 – 24

$191 CAD per night

Guest favourite

Apartment in Panamá

4.96 out of 5 average rating, 219 reviews

Mola Studio | By Paradox

If you're looking to get sumerged into real Panama and live among the real locals. This is the right place to be. We must clarify that we are NOT located in Casco Viejo specifically. We are located on the historic Central Avenue better known as La Peatonal, a few blocks from Casco Viejo. It has all the necessary amenities like a full kitchen, hot shower and A/C. Close to pharmacies, supermarkets, Subway/Bus stations, banks/ATMs, private parking lots, and a wide range of restaurants.

Dec. 2 – 9

$74 CAD per night

Guest favourite

Apartment in Panamá

4.98 out of 5 average rating, 110 reviews

Ocre Studio | By Paradox

If you're looking to get sumerged into real Panama and live among the real locals. This is the right place to be. We must clarify that we are NOT located in Casco Viejo specifically. We are located on the historic Central Avenue better known as La Peatonal, a few blocks from Casco Viejo. It has all the necessary amenities like a full kitchen, hot shower and A/C. Close to pharmacies, supermarkets, Subway/Bus stations, banks/ATMs, private parking lots, and a wide range of restaurants.

Sep. 26 – Oct. 3

$74 CAD per night

Guest favourite

Apartment in Panamá

4.92 out of 5 average rating, 153 reviews

TINY HOUSE WITH PRIVATE ENTRANCE AND PARKING

A PRIVATE AND UNIQUE PLACE TO STAY One bedroom mini house (whit an extra sof bed in the living room) spacious and very comfortable. Great area just meters walking from the famous CINTA COSTERA of Av. Balboa Around are Supermarket, restaurants, banks, gym, car rental. PLUS: LAUNDRY center available at home. Less than 2km from the best shopping ceter MULTIPLAZA Mini 1 bedroom house plus sofa bed in the living room, walking meters from the famous Cinta Costera, has a washer/dryer

Oct. 7 – 14

$78 CAD per night

Apartment in Panamá

4.82 out of 5 average rating, 136 reviews

Deluxe rooftop with pool Ab4

**Update: Newly renovated with anti-noise windows for a perfect rest** Apartment recently renovated and decorated by an international designer, on the main avenue of Casco Viejo (nocturnal silence area) with views of the church and the most beautiful existing ruins. In addition to a 180º rooftop with an infinity pool. One bedroom apartment with King bed, living room, dining room, kitchen, beautiful bathroom, 55" Smart Tv, private balcony with views of the Church, etc.

Dec. 8 – 15

$221 CAD per night

Guest favourite

Apartment in Panamá

4.97 out of 5 average rating, 33 reviews

Entire home with parking

Bienvenidos to our entire modern and central one-bedroom apartment! Stylishly decorated and equipped with everything you need for your stay, this space is perfect for those looking for comfort and convenience in the city center. With a king bed, a living room with a sofa and a TV, and a full kitchen, you'll feel right at home. In addition, the location in the center and is close to public transportation. Make this apartment your home during your city visit!

Dec. 8 – 15

$100 CAD per night

Guest favourite

Apartment in Panamá

4.94 out of 5 average rating, 33 reviews

Apart from full luxury studio in Panama.

Located in San Francisco, one of the quintessential exclusive areas in Panama, where gastronomy, history, modernity and entertainment are magically combined. Wonderful location close to must-see destinations, gym, swimming pool, coworking, pet spa and terrace. The parking lot is charged. Modern and functional, this apartment features a queen bed room, fully equipped kitchen, Wifi, TV, a spectacular balcony with ocean views, laundry center and sofa bed.

Apr. 16 – 23

$113 CAD per night

Apartment in Panamá

4.82 out of 5 average rating, 33 reviews

Beautiful apartment in Casco Viejo

Located in the heart of Casco Viejo. It has a button service that takes your luggage to the apartment, it has a rooftop where you can watch the sunset with the view of the city, the canal and the majestic sea. The building's ground floor is home to La Cuadra Market where there are a variety of renowned restaurants with different styles of food, as well as a bar. Close to everything, you can walk around everything and enjoy every place it offers you.

Feb. 18 – 25

$121 CAD per night

Guest favourite

Apartment in Panama City

4.98 out of 5 average rating, 40 reviews

Stunning views from the clouds!

*** Internet 500Mbps Wifi Pro *** *** Netflix, Prime Video, HBOmax, Youtube Premium *** Cozy and spectacular apartment all dressed in white. You will enjoy daily incredible views of the symbols of Panama: the islands, Causeway, Old Town, Canal, Metropolitan park. In this bubble over the bay, you will feel like in the clouds! Place of inspiration and relaxation, strategically located, you will have the whole city at your feet!

Aug. 10 – 17

$260 CAD per night

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Popular amenities for Panama City apartment rentals

Free parking on premises

Air conditioning

Weekly apartment rentals

Guest favourite

Apartment in Panamá

5.0 out of 5 average rating, 19 reviews

Luxury Apartment Panama Centro, Banking Area

Dec. 2 – 9

$79 CAD per night

Guest favourite

Apartment in Panamá

4.92 out of 5 average rating, 39 reviews

Beautiful apartment in Casco Viejo ST. George D

Jun. 1 – 8

$205 CAD per night

Guest favourite

Apartment in Panamá

4.97 out of 5 average rating, 63 reviews

Superb Apartment In The Center Of Panama City

Jul. 25 – Aug. 1

$111 CAD per night

Guest favourite

Apartment in Panamá

5.0 out of 5 average rating, 48 reviews

City center apartment with pool and ocean view

May 27 – Jun. 3

$136 CAD per night

Apartment in Panama City

4.85 out of 5 average rating, 66 reviews

Best Location-Fancy Apartment in CascoViejo

Jul. 20 – 27

$165 CAD per night

Apartment in Panamá

4.94 out of 5 average rating, 18 reviews

The Sands Infinity pool Ave. Balboa vista al mar

Nov. 6 – 13

$170 CAD per night

Guest favourite

Apartment in Panamá

4.97 out of 5 average rating, 29 reviews

New Apartment in Panama City

Sep. 3 – 10

$115 CAD per night

Guest favourite

Apartment in Panama City

5.0 out of 5 average rating, 15 reviews

BEST VIEW in Old Town, Panama (Casco Viejo)

Oct. 8 – 15

$159 CAD per night

Private apartment rentals

Apartment in Panamá

4.8 out of 5 average rating, 106 reviews

Best View In Panama! Best Located Unique Full Apt.

Mar. 27 – Apr. 3

$149 CAD per night

Guest favourite

Apartment in El Cangrejo

5.0 out of 5 average rating, 15 reviews

Spacious Executive High-Floor Quiet Apt w/Balcony

Jun. 19 – 26

$143 CAD per night

Guest favourite

Apartment in Panama City

4.85 out of 5 average rating, 33 reviews

Centrally-located, one bedroom apartment in Casco

May 8 – 15

$108 CAD per night

Guest favourite

Apartment in Panamá

4.97 out of 5 average rating, 37 reviews

Beautiful apartment in Casco Viejo, Apt #4

May 10 – 17

$200 CAD per night

Guest favourite

Apartment in Panamá

4.96 out of 5 average rating, 68 reviews

Beautiful boutique apartment in Avenida Balboa

Jun. 7 – 14

$163 CAD per night

Guest favourite

Apartment in Panamá

5.0 out of 5 average rating, 16 reviews

Yoo tower Ocean View apt in the heart of panama

Mar. 12 – 19

$247 CAD per night

Guest favourite

Apartment in Panamá

4.91 out of 5 average rating, 74 reviews

Cozy apartment near Casco Viejo

Sep. 29 – Oct. 6

$107 CAD per night

Guest favourite

Apartment in Panama City

5.0 out of 5 average rating, 6 reviews

Amazing Ocean Front Apt With Infinity Pool

Jul. 1 – 8

$111 CAD per night

Apartment rentals with a hot tub

Apartment in Panamá

4.84 out of 5 average rating, 114 reviews

Your apartment in Panama! with a nice view of the city

Oct. 23 – 30

$107 CAD per night

Guest favourite

Apartment in Panamá

4.94 out of 5 average rating, 18 reviews

King Bed Suite / 280 Degree View / 500mbs WiFi

Feb. 2 – 9

$461 CAD per night

Guest favourite

Apartment in Panama City

5.0 out of 5 average rating, 7 reviews

NEW Poolside Luxury Living - Monthly Discount$

May 29 – Jun. 5

$153 CAD per night

Guest favourite

Apartment in Panama City

4.98 out of 5 average rating, 47 reviews

5A - Boutique Apartment ! High end furnished! 4BR

Mar. 16 – 23

$260 CAD per night

Apartment in Panamá

4.83 out of 5 average rating, 24 reviews

Hotel with free breakfast Gym Pool Jacuzzi

Aug. 3 – 10

$136 CAD per night

Apartment in Panama City

5.0 out of 5 average rating, 5 reviews

Amazing Ocean View 1bed Suite

Sep. 24 – Oct. 1

$119 CAD per night

Guest favourite

Apartment in Panamá

5.0 out of 5 average rating, 12 reviews

Oceanview Apt Near Panama City w/ King Bed & More

Aug. 19 – 26

$374 CAD per night

Apartment in Panama City

4.88 out of 5 average rating, 24 reviews

3 bedroom penthouse with spectacular views!

Dec. 29 – Jan. 5

$378 CAD per night

Quick stats about apartment rentals in Panama City

Total rentals
2.2K properties
Rentals with a pool
1.4K properties have a pool
Pet-friendly rentals
730 properties allow pets
Family-friendly rentals
750 properties are a good fit for families
Total number of reviews
44K reviews
Nightly prices starting at
$14 CAD before taxes and fees

Destinations to explore