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Villa vacation rentals in Panama City

Find and book unique villas on Airbnb

Top-rated villa rentals in Panama City

Guests agree: these villas are highly rated for location, cleanliness, and more.

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Superhost
Villa in Coronado
4.85 out of 5 average rating, 39 reviews

Beachfront Sanctuary: Nature, Serenity, And Peace

Modern beachfront house with direct ocean access, fire pit & BBQ area. 3 bedrooms for 6-8 guests, master suite with private ocean-view balcony. Gourmet kitchen with stunning onyx stone counters, therapeutic Kohler showers, organic garden. 3 parking spaces in secure gated community with 24/7 security, Olympic pool, kids pool, tennis court, playgrounds. Walk to famous Luna Rossa Italian restaurant, Picasso bar & local shops. Your private beachfront paradise where every weekend feels like vacation!

Superhost
A welcoming private villa is surrounded by tall trees, showcasing a spacious layout. A swimming pool and trampoline are visible in the backyard, and the exterior features large windows allowing natural light. A green pathway leads to the entrance, emphasizing the serene, forested environment.
Villa in Panamá
4.79 out of 5 average rating, 24 reviews

Spacious Mountain Getaway in Paradise Cloud Forest

Private Villa located at Chagres National Park; a rainforest reserve only 30 minutes away from the airport and 50 minutes from Panama City. At 1,007 meters altitude, you will enjoy the perfect climate, bird watching, beautiful river walks, waterfalls, and many hiking trails full of wildlife, enjoy our mountain's pure air or simply relax in Nature. Bring the whole family to this great place with lots of room for fun. Bring your pets our land is completely fenced, they can run free in a vast space

Guest favourite
A tranquil beachfront scene features several hammocks strung between palm trees on soft sand. Blue lounge chairs are positioned alongside the water, with gentle waves lapping at the shore under a clear sky.
Villa in Chame District
4.86 out of 5 average rating, 233 reviews

Surf Relax Play Pacific Ocean View Villa

White sand, surf-able waves, or just a comfortable chill vibe to enjoy the tropical weather of Panama. Playa Caracol is about an hour and 10 minutes drive from the city. This spacious, 2 bedroom, 2 bath villa with it's Pacific Ocean front location is the perfect place for you to enjoy an unforgettable family vacation. Walk out to the beach just steps from the villa, swim in the pool next to this villa or enjoy the resort pools and amenities. Or hike the nearby mountains with a local guide. PET

Guest favourite
A spacious swimming pool is framed by lounge chairs, with a bright pink float positioned in the water. The villa's exterior is visible in the background, showcasing a large parking area and covered terrace with a red roof, surrounded by greenery.
Villa in Portobelo
4.92 out of 5 average rating, 25 reviews

Villa con piscina, cancha de fútbol y arroyo

Tranquila y espaciosa villa en Portobelo, Buenaventura. Disfrute de una villa con un gigante jardín, rio, cancha de fútbol, piscina con cascada y tobogán , 2 bohíos, áreas de barbacoa, terraza. 1 recámara principal con cama king y baño privado. 2 recamaras con 2 camas full. 1 baño en la sala. 1 baño en el área de la piscina y ducha externa. Sala, Comedor. Televisor por cable. Cocina equipada. Hamacas. * la casa está equipada con camas para 10 personas, llevar colchones inflables con sábanas.

Superhost
The outdoor area features a swimming pool with sun loungers arranged around it. Umbrellas provide shade, and the surrounding greenery enhances the space. In the background, the ocean and sky create a scenic backdrop, with the villa positioned to the left.
Villa in Chame
4.82 out of 5 average rating, 114 reviews

Ocean Pergola Villa (C10-PBB) 2 bed, 2 bath

Unique place steps away from the ocean and fully furnished ground floor unit 2 bed/2 bath apt has an open concept living, dining & kitchen space and an outside pergola area. (4 guests). This is a unique villa apartment over looking the picturesque Playa Caracol coast with ocean front and majestic mountain views. Playa Caracol is located on the beach of Chame and is a newly developed area with expansion for the property and amenities. 1km of beach to offer you the best beach experience around.

Guest favourite
Large sliding glass doors open to reveal a view of the serene garden and swimming pool, complemented by lush greenery. A cozy corner with a comfortable sofa and decorative plants adds to the relaxed indoor ambiance.
Villa in Panamá
4.86 out of 5 average rating, 147 reviews

Bonita casa con piscina a pasos de la playa

Relájate con toda la familia en muestro Rincón de Flavio, un lugar tranquilo para quedarse el fin de semana o tanto tiempo como necesites. Tres recamaras con dos baños. Plenamente equipada y decorada con estilo tropical. AHORA SI QUE TENEMOS AIRE ACONDICIONADO EN TODOS LOS CUARTOS. Con todo lo que necesitas para disfrutar y relajarte. A 5 minutos caminando de la playa de Coronado y cerca de restaurantes y supermercados. Amplio Jardín, ping pong, piscina y cómodo patio con barbacoa.

Guest favourite
A multi-story mansion is showcased overlooking a vibrant swimming pool, adorned with inflatable toys including a pink flamingo and a whale. Bright umbrellas provide shade over red loungers, all set against a backdrop of lush greenery and a partially cloudy sky.
Villa in Panamá
4.97 out of 5 average rating, 60 reviews

Breathtaking Views Mansion w/King Beds

Book your next thrilling Panama City vacation at our dreamy 11,500 sq. foot multi-story family mansion, superbly located on a hilltop high above the metropolis in this affluent neighborhood. Ideal for longer stays. Discover the vibrant buzz of Cinta Costera or explore the UNESCO world heritage sites at Casco Viejo – all under 5 km away from your doorstep. Enjoy a refreshing dip into the swimming pool and admire the sublime views of the Panama City Skyline from our unique roof terrace.

Guest favourite
The private outdoor pool is set against a backdrop of lush greenery and the home's elegant architecture. Comfortable seating arrangements are positioned nearby on the pool deck, inviting relaxation. Large windows reflect natural light, enhancing the spaciousness of the surrounding area.
Villa in Punta Paitilla
4.98 out of 5 average rating, 93 reviews

Beautiful House in Panama w/ King Beds + Pool

Welcome to our stunning home located in the heart of Punta Paitilla, Panama. This beautiful property boasts 4 bedrooms, 3.5 bathrooms, 7 beds, and can comfortably accommodate up to 11 guests, making it the perfect choice for families or groups of friends. This property also features a private outdoor pool, where you can soak up the sun and cool off on hot days. For those who like to stay active, there is a gym on-site where you can work out and stay in shape during your stay.

Guest favourite
A table is set outdoors, featuring two glasses and a bottle of wine. In the background, a pool with clear water reflects the lush greenery of palm trees and tropical plants. Natural light enhances the scene, providing a serene and inviting atmosphere.
Villa in Maria Chiquita
4.96 out of 5 average rating, 25 reviews

Bella Villa en Playa Escondida

Descubre el encanto de Playa Escondida Resort & Marina en la Provincia de Colón, María Chiquita. Arena blanca, aguas cristalinas y jardines tropicales te esperan. Piscinas, hamacas, bohíos y áreas de juego para niños. Canchas deportivas y naturaleza para los amantes del deporte. A una hora de Ciudad de Panamá, una hermosa Villa a estrenar junto a una laguna con terraza, jacuzzi privado y bbq te esperan. Naturaleza y lujo se fusionan para un refugio sofisticado e inolvidable.

Top guest favourite
A serene swimming pool is depicted surrounded by lush palm trees, with the tranquil sea visible in the background. The water's clear blue tiles reflect the sky and nearby greenery, while the gentle curvature of the pool edge invites relaxation.
Villa in Portobelo
5 out of 5 average rating, 74 reviews

Entire Villa with pool in front of beach!

Beautiful spacious 4 bedroom villa right in front of the sea. Enjoy the swimming pool with your family, then take a dip into the sea only steps away. Very pet friendly! Take a boat trip for the day with a local certified tour guide from portobelo town. Every room has full AC, including the living room - but please be conscious of the environment when using ACs. Excellent WiFi ! Open Kitchen, with breakfast included. We can also arrange for lunch - fresh lobster!

Top guest favourite
The image shows a bright outdoor area featuring a clear blue swimming pool bordered by light stone paths and lush green grass. A tall palm tree provides shade in the foreground, while the backyard includes a single-story house and an open patio area under a roof.
Villa in Santa Cruz De Chinina
4.97 out of 5 average rating, 133 reviews

Beach House with Pool/Gazebo in Punta Chame!

"Disconnect from the routine and enjoy a sunny environment. Just breathe fresh air in a different surroundings. Enjoy a few days in the pool, relaxed in a hammock and of course steps from a spectacular beach with views of the city and islands. The house has 4 bedrooms, 3.5 bathrooms, electric plant and all the facilities to enjoy and rest. Close to restaurants and the best beach to do and see kitesurfing adventures, fish, SUP, etc. Only 90 minutes from the city"

Top guest favourite
An inviting infinity pool overlooks a stunning coastal view. A spacious seating area, featuring colorful cushions, complements the serene atmosphere. Natural light fills the space, enhancing the connection to the outdoors, while the blue waters of the pool blend seamlessly with the distant ocean.
Villa in Cacique
5 out of 5 average rating, 44 reviews

CARA AL MAR Cacique (Parque de Portobello)

Au beau milieu du Parque National de Portobello (accès uniquement en 4x4, AWD 4 roues motrices) blotti au sommet de la colline, entre ciel et mer, à l'abri de tout regard, aux premières loges, un petit nid d'amour douillet très privé pour se reposer et se déconnecter (en couple ou entre amis), confortable, lumineux (grandes et hautes baies vitrées), spacieux, frais (clim centrale), témoin d'un spectacle grandiose qui vous attend...!

Popular amenities for Panama City villa rentals

Quick stats about villa rentals in Panama City

  • Total vacation rentals

    Explore 10 vacation rentals in Panama City

  • Nightly prices starting at

    Panama City vacation rentals start at $112 CAD per night before taxes and fees

  • Verified guest reviews

    Over 340 verified reviews to help you choose

  • Family-friendly vacation rentals

    10 properties offer extra space and kid-friendly amenities

  • Pet-friendly vacation rentals

    Find 10 rentals that welcome pets

  • Vacation rentals with a pool

    10 properties feature pools

  • Rentals with dedicated workspaces

    10 properties have a dedicated workspace

  • Wifi availability

    10 of Panama City vacation rentals include wifi access

  • Popular amenities for guests

    Guests love Kitchen, Wifi, and Pool across Panama City rentals

  • 4.7 Average rating

    Panama City stays receive an average rating of 4.7 out of 5 from guests

  • Nearby attractions

    Panama City’s top spots, include Miraflores Locks, Museo de Arte Contemporáneo, and Santo Tomas (Panama Metro)

Destinations to explore

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