
Vacation rentals in Panama City
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Top-rated vacation rentals in Panama City
Guests agree: these stays are highly rated for location, cleanliness, and more.
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Vacation rentals for every style
Get the amount of space that is right for you.
Popular amenities for Panama City vacation rentals
Other great vacation rentals in Panama City
Guest favourite

Apartment in Panamá
4.96 out of 5 average rating, 47 reviewsNuevo apartamento tipo estudio frente al Mar
Superhost

Apartment in Marbella
5 out of 5 average rating, 5 reviewsYoo Panama -Lujoso y confortable
Top guest favourite

Home in Panamá
5 out of 5 average rating, 5 reviewsLa Casa de la Cascada
Top guest favourite

Apartment in Costa del Este
5 out of 5 average rating, 17 reviewsElegante Apt en Costa del Este. Amenidades Premium
Guest favourite

Apartment in Marbella
5 out of 5 average rating, 12 reviewsLuxury 2BR w/Ocean Views – 27th Fl, Wanders YOO
Top guest favourite

Apartment in Panamá
5 out of 5 average rating, 76 reviewsApartamento Nuevo en calle 50
Top guest favourite

Apartment in Marbella
4.97 out of 5 average rating, 34 reviewsUnique Luxury 3-story Loft at the Yoo
Top guest favourite

Apartment in Ciudad de Panama
5 out of 5 average rating, 8 reviewsYOO Panama · Luxury signature ocean view. 57th fl
Quick stats about vacation rentals in Panama City
Total rentals
4.7K properties
Nightly prices starting at
$14 CAD before taxes and fees
Total number of reviews
108K reviews
Family-friendly rentals
1.5K properties are a good fit for families
Pet-friendly rentals
1.6K properties allow pets
Rentals with a pool
2.6K properties have a pool
Destinations to explore
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- Rentals with outdoor seating Panama City
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- Rentals with a fireplace Panama City
- Rentals with a home theater Panama City
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- Rentals with pools Panama City
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- Bed and breakfasts Panama City
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- Rentals with an accessible height bed Panama City
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- Hotel rentals Panama City
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- Things to do Panama City
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- Things to do Panamá Province
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- Nature and outdoors Panamá Province
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- Food and drink Panamá Province
- Sightseeing Panamá Province
- Things to do Panama
- Nature and outdoors Panama
- Sightseeing Panama
- Sports activities Panama
- Tours Panama
- Entertainment Panama
- Art and culture Panama
- Food and drink Panama