Guesthouse vacation rentals in Charleston

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Top-rated guesthouses in Charleston

Guests agree: these guesthouses are highly rated for location, cleanliness, and more.

Guest favourite
Guesthouse in Summerville
★Delightful guest house near historic plantations★
Nestled in the Historic Plantation District between Summerville & Charleston, our timberframe "bunkhouse" offers privacy, comfort & convenience. This 850+ sq ft retreat includes full kitchen & bath, 2 dbl beds, twin bed & plenty of living space. There's a private entrance, so come & go as you please (we're right next door if you need us). We're minutes from Middleton Place, Drayton Hall & Magnolia Gardens, an easy drive to downtown Charleston, historic Summerville, beaches & golf courses.
Sep. 4 – 11
$253 CAD per night
4.98 out of 5 average rating, 628 reviews
Guest favourite
Guesthouse in Charleston
Charleston's Coolest Neighborhood
You can't beat the location! You'll be 5-10 minutes from downtown Charleston, but with free off-street parking, AND you can walk to dozens of bars, restaurants, coffee shops, etc. Avondale is Central to all parts of Charleston, and its a cinch to drive to everywhere from here. This studio apartment is private, modern, and newly renovated. You'll have a kitchenette, grill, outdoor seating, and access to beach equipment. Also only a 5 minute walk to the West Ashley Greenway for biking/jogging!
Aug. 5 – 12
$243 CAD per night
4.93 out of 5 average rating, 697 reviews
Guest favourite
Guesthouse in Charleston
Riverland Terrace Guesthouse
Private and quiet guest suite perfect for nature lovers. Our guest house is tucked up against a small marshy area in our backyard on James Island. Located about 5 minutes to downtown Charleston, 5 minutes to John's Island and 15 minutes to Folly Beach. Five minute walk to the Pour House and all terrace area restaurants and the terrace theater. We are a very laid back couple looking for laid back guests who need a quiet and peaceful place to use as their base while exploring Charleston.
May 23 – 30
$178 CAD per night
4.91 out of 5 average rating, 166 reviews

Popular amenities for Charleston guesthouses

Family-friendly guesthouses

Guest favourite
Guesthouse in Ridgeville
Pond House Bungalow at Natural Gathering Grounds
Nov. 16 – 23
$106 CAD per night
4.82 out of 5 average rating, 207 reviews
Guest favourite
Guesthouse in North Charleston
Cozy Park Circle, Charleston Guest House
Jul. 31 – Aug. 7
$157 CAD per night
4.93 out of 5 average rating, 337 reviews
Guest favourite
Guesthouse in Charleston
Mother in Law in James Island Riverland Terrace
Aug. 26 – Sep. 2
$185 CAD per night
4.92 out of 5 average rating, 291 reviews
Guest favourite
Guesthouse in Mount Pleasant
Bungalow Under The Oaks
Jul. 11 – 18
$250 CAD per night
4.98 out of 5 average rating, 209 reviews
Guest favourite
Guesthouse in North Charleston
The Park Circle Clerestory Studio Guest House
May 20 – 27
$256 CAD per night
5.0 out of 5 average rating, 102 reviews
Guest favourite
Guesthouse in Johns Island
Private waterfront apt in the oaks
Nov. 16 – 23
$310 CAD per night
4.98 out of 5 average rating, 231 reviews
Guest favourite
Guesthouse in Charleston
The White House of Avondale
Aug. 20 – 27
$247 CAD per night
4.95 out of 5 average rating, 318 reviews
Superhost
Guesthouse in North Charleston
Park Circle Bungalow Loft
Jul. 27 – Aug. 3
$296 CAD per night
4.86 out of 5 average rating, 434 reviews
Guest favourite
Guesthouse in Charleston
Island Oasis—Near Downtown
May 23 – 30
$339 CAD per night
4.91 out of 5 average rating, 636 reviews
Guest favourite
Guesthouse in Mount Pleasant
Green Garden Studio @greengardenstudio2017
Jun. 10 – 17
$270 CAD per night
4.95 out of 5 average rating, 214 reviews
Guest favourite
Guesthouse in Charleston
Cozy Island Cottage
Jun. 24 – Jul. 1
$543 CAD per night
4.93 out of 5 average rating, 312 reviews
Guest favourite
Guesthouse in Mount Pleasant
Close to beach , downtown and Shem creek
Nov. 23 – 30
$320 CAD per night
4.85 out of 5 average rating, 215 reviews

Guesthouses with a patio

Guest favourite
Guesthouse in Charleston
Quaint Cottage Studio in Ashley Forest (Avondale)
Feb. 15 – 22
$209 CAD per night
4.93 out of 5 average rating, 157 reviews
Guest favourite
Guesthouse in Charleston
Private Backyard With Fire Pit, 15 Min to Downtown
Dec. 10 – 17
$282 CAD per night
4.98 out of 5 average rating, 110 reviews
Guest favourite
Guesthouse in Charleston
Studio Apartment Minutes to Downtown Charleston
Oct. 11 – 18
$311 CAD per night
4.97 out of 5 average rating, 115 reviews
Guest favourite
Guesthouse in Goose Creek
The Blue Secret
Apr. 24 – May 1
$166 CAD per night
5.0 out of 5 average rating, 41 reviews
Guest favourite
Guesthouse in Hanahan
The Violet Villa w/ no cleaning fee
Jun. 9 – 16
$198 CAD per night
4.98 out of 5 average rating, 60 reviews
Guest favourite
Guesthouse in Charleston
BoHo styled casita in adorable neighborhood...
Jul. 24 – 31
$287 CAD per night
4.95 out of 5 average rating, 81 reviews
Guest favourite
Guesthouse in Charleston
Spacious 1 bedroom cottage in Avondale
Jun. 5 – 12
$232 CAD per night
4.94 out of 5 average rating, 67 reviews
Superhost
Guesthouse in Johns Island
Cozy Cottage! 5 mins from Kiawah!
Jul. 24 – 31
$293 CAD per night
4.9 out of 5 average rating, 87 reviews
Guest favourite
Guesthouse in Johns Island
Driftwood Cottage
Aug. 29 – Sep. 5
$281 CAD per night
5.0 out of 5 average rating, 37 reviews
Guest favourite
Guesthouse in Mount Pleasant
Coastal Charm: Village Hideaway
Jun. 16 – 23
$527 CAD per night
5.0 out of 5 average rating, 17 reviews
Guest favourite
Guesthouse in Charleston
The James: “Tiny” Home b/w Downtown & Folly
Nov. 20 – 27
$473 CAD per night
4.98 out of 5 average rating, 51 reviews
Guest favourite
Guesthouse in Charleston
1/1 sleeps 3 ADU Modern+Amazing!
Mar. 27 – Apr. 3
$276 CAD per night
5.0 out of 5 average rating, 14 reviews

Guesthouse rentals with a washer and dryer

Guest favourite
Guesthouse in Mount Pleasant
Cozy Apartment in Mount Pleasant
Sep. 23 – 30
$209 CAD per night
4.97 out of 5 average rating, 216 reviews
Guest favourite
Guesthouse in Charleston
Large Guesthouse with Private Dock & Marsh Views
Oct. 18 – 25
$386 CAD per night
4.98 out of 5 average rating, 132 reviews
Guest favourite
Guesthouse in Charleston
Cute, Cozy, Charleston Cottage
Jul. 25 – Aug. 1
$255 CAD per night
4.9 out of 5 average rating, 533 reviews
Guest favourite
Guesthouse in Mount Pleasant
Old Mt. Pleasant/Shem Creek close to Sullivans/DT
Oct. 18 – 25
$321 CAD per night
4.98 out of 5 average rating, 420 reviews
Guest favourite
Guesthouse in Charleston
James Island "La Casita" Nestled btw Beach & City
Aug. 8 – 15
$302 CAD per night
5.0 out of 5 average rating, 209 reviews
Guest favourite
Guesthouse in Mount Pleasant
#1 SC AIRBNB IN MT. PLEASANT OLD VILLAGE. BEACHES!
Apr. 14 – 19
$349 CAD per night
4.98 out of 5 average rating, 252 reviews
Guest favourite
Guesthouse in Mount Pleasant
Upscale Couple's Escape | Beach & Downtown CHS
Dec. 16 – 23
$474 CAD per night
4.99 out of 5 average rating, 238 reviews
Guest favourite
Guesthouse in Charleston
Redesigned suite! 12min to city, pet-friendly
Aug. 1 – 8
$250 CAD per night
4.98 out of 5 average rating, 192 reviews
Guest favourite
Guesthouse in Charleston
Detached Guest Suite
Nov. 23 – 30
$221 CAD per night
4.98 out of 5 average rating, 243 reviews
Guest favourite
Guesthouse in Summerville
Tiny Oak Cottage in Historic Downtown Summerville
Sep. 13 – 20
$154 CAD per night
4.97 out of 5 average rating, 207 reviews
Guest favourite
Guesthouse in Mount Pleasant
Shem Creek Bungalow: Coastal Comfort Redefined
Jun. 13 – 20
$462 CAD per night
4.97 out of 5 average rating, 246 reviews
Superhost
Guesthouse in Charleston
The Haven Home | Blocks From King St.
May 11 – 18
$533 CAD per night
4.84 out of 5 average rating, 161 reviews

Quick stats about guesthouse rentals in Charleston

Total rentals

220 properties

Rentals with dedicated workspaces

90 properties have a dedicated workspace

Rentals with a pool

10 properties have a pool

Pet-friendly rentals

40 properties allow pets

Family-friendly rentals

40 properties are a good fit for families

Total number of reviews

23K reviews

Destinations to explore