Guesthouse vacation rentals in Charleston
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Top-rated guesthouses in Charleston
Guests agree: these guesthouses are highly rated for location, cleanliness, and more.
Vacation rentals for every style
Get the amount of space that is right for you.
Popular amenities for Charleston guesthouses
Family-friendly guesthouses
Guesthouse in North Charleston
5.0 out of 5 average rating, 110 reviewsThe Park Circle Clerestory Studio Guest House
Jun. 20 – 27
Guesthouse in Charleston
4.95 out of 5 average rating, 331 reviewsThe White House of Avondale
Oct. 8 – 15
Guesthouse in Ridgeville
4.82 out of 5 average rating, 212 reviewsPond House Bungalow at Natural Gathering Grounds
Nov. 5 – 12
Guesthouse in Charleston
4.91 out of 5 average rating, 647 reviewsIsland Oasis—Near Downtown
Oct. 21 – 28
Guesthouse in North Charleston
4.86 out of 5 average rating, 441 reviewsPark Circle Jungalow Loft
Aug. 7 – 14
Guesthouse in Johns Island
4.98 out of 5 average rating, 238 reviewsPrivate waterfront apt in the oaks
Dec. 28 – Jan. 4
Guesthouse in Summerville
4.94 out of 5 average rating, 211 reviewsNina's Cottage -Historic Downtown Summerville
Mar. 16 – 23
Guesthouse in Summerville
4.87 out of 5 average rating, 747 reviewsNew Loft in Historic Summerville
Feb. 4 – 11
Guesthouses with a patio
Guesthouse in Johns Island
4.91 out of 5 average rating, 104 reviewsCozy Cottage! 5 mins from Kiawah!
Oct. 7 – 14
Guesthouse in Charleston
4.98 out of 5 average rating, 120 reviewsPrivate Backyard With Fire Pit, 15 Min to Downtown
Sep. 12 – 19
Guesthouse in Charleston
4.97 out of 5 average rating, 125 reviewsStudio Apartment Minutes to Downtown Charleston
Apr. 13 – 20
Guesthouse in Hanahan
4.99 out of 5 average rating, 76 reviewsThe Violet Villa w/ no cleaning fee
Aug. 5 – 12
Guesthouse in Charleston
4.98 out of 5 average rating, 45 reviewsCountry in the City, "The Outback"
Apr. 16 – 23
Guesthouse in Charleston
4.94 out of 5 average rating, 78 reviewsSpacious 1 bedroom cottage in Avondale
Mar. 27 – Apr. 3
Guesthouse in Goose Creek
4.96 out of 5 average rating, 49 reviewsThe Blue Secret
Jun. 18 – 25
Guesthouse in Mount Pleasant
5.0 out of 5 average rating, 25 reviewsCoastal Charm: Village Hideaway
Dec. 14 – 21
Guesthouse rentals with a washer and dryer
Guesthouse in Charleston
4.98 out of 5 average rating, 244 reviewsDetached Guest Suite
Jan. 23 – 30
Guesthouse in North Charleston
4.94 out of 5 average rating, 111 reviewsNewly Renovated Studio in Park Circle
Jun. 2 – 9
Guesthouse in Charleston
5.0 out of 5 average rating, 216 reviewsJames Island "La Casita" Nestled btw Beach & City
Oct. 2 – 9
Guesthouse in Mount Pleasant
4.98 out of 5 average rating, 434 reviewsOld Mt. Pleasant/Shem Creek close to Sullivans/DT
Sep. 30 – Oct. 7
Guesthouse in Charleston
4.99 out of 5 average rating, 204 reviewsRedesigned suite! 12min to city, pet-friendly
Dec. 11 – 18
Guesthouse in Charleston
4.99 out of 5 average rating, 140 reviewsLarge Guesthouse with Private Dock & Marsh Views
Sep. 2 – 9
Guesthouse in Mount Pleasant
4.99 out of 5 average rating, 247 reviewsUpscale Couple's Escape | Beach & Downtown CHS
Jul. 5 – 12
Guesthouse in Mount Pleasant
4.98 out of 5 average rating, 116 reviewsBeach, downtown, Alhambra Hall weddings so close!
Jul. 28 – Aug. 4
Quick stats about guesthouse rentals in Charleston
Total rentals
230 properties
Rentals with dedicated workspaces
100 properties have a dedicated workspace
Rentals with a pool
10 properties have a pool
Pet-friendly rentals
50 properties allow pets
Family-friendly rentals
40 properties are a good fit for families
Total number of reviews
23K reviews
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