
Guesthouse vacation rentals in Charleston
Find and book unique guesthouse rentals on Airbnb
Top-rated guesthouses in Charleston
Guests agree: these guesthouses are highly rated for location, cleanliness, and more.
Vacation rentals for every style
Get the amount of space that is right for you.
Popular amenities for Charleston guesthouses
Family-friendly guesthouses

Little Turtle

Private Coastal Cottage-Near Beaches & Charleston!

Charming Charleston StudioOne!

Riverland Terrace Guesthouse

Cottage apartment near beach and downtown

Liz Lane Cottage- entire guesthouse

Creekside Cottage (Tiny Home)

Olde Village Loft - Unique Park Circle Experience
Guesthouses with a patio

Quaint Cottage Studio in Ashley Forest (Avondale).

Spacious 1 bedroom cottage in Avondale

Driftwood Cottage

My Happy Place

The Violet Villa w/no cleaning fee

Cozy Cottage! 5 mins from Kiawah!

5 Star Private Guest House • Heart of Park Circle

Luxury Loft (2 miles from Folly Beach)
Guesthouse rentals with a washer and dryer

Peaceful Garden Cottage Retreat

Island Oasis Hideaway | Easy Beach & City Access

Beach, downtown, Alhambra Hall weddings so close!

Cozy Park Circle, Charleston Guest House

Serene Location - Next to Hampton Park: Haven Hom

The Guesthouse at Old Orchard

Shem Creek Bungalow: Coastal Comfort Redefined

Old Mt. Pleasant/Shem Creek close to Sullivans/DT
Quick stats about guesthouse rentals in Charleston
Total rentals
220 properties
Total number of reviews
26K reviews
Family-friendly rentals
30 properties are a good fit for families
Pet-friendly rentals
50 properties allow pets
Rentals with a pool
10 properties have a pool
Rentals with dedicated workspaces
100 properties have a dedicated workspace
Destinations to explore
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- Rentals with a firepit Charleston
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- Guesthouse rentals Charleston County
- Guesthouse rentals South Carolina
- Guesthouse rentals United States
- Park Circle
- Hunting Island State Park Beach
- Sullivan's Island Beach
- Bulls Island
- Middleton Place
- The Golf Club at Wescott Plantation
- Waterfront Park
- Shem Creek Park
- James Island County Park
- Harbor Island Beach
- Angel Oak Tree
- Hampton Park
- The Charleston Museum
- Secession Golf Club
- Driftwood Beach
- Morris Island Lighthouse
- Sandy Point Beach
- Isle of Palms Beach
- The Beach Club
- Seabrook Island Beach
- White Point Garden
- Hunting Island Beach
- Edingsville Beach
- Seabrook Beach
- Things to do Charleston
- Nature and outdoors Charleston
- Sightseeing Charleston
- Sports activities Charleston
- Food and drink Charleston
- Tours Charleston
- Art and culture Charleston
- Things to do Charleston County
- Art and culture Charleston County
- Food and drink Charleston County
- Sports activities Charleston County
- Tours Charleston County
- Sightseeing Charleston County
- Nature and outdoors Charleston County
- Things to do South Carolina
- Nature and outdoors South Carolina
- Sports activities South Carolina
- Art and culture South Carolina
- Sightseeing South Carolina
- Entertainment South Carolina
- Wellness South Carolina
- Tours South Carolina
- Food and drink South Carolina
- Things to do United States
- Tours United States
- Nature and outdoors United States
- Sightseeing United States
- Art and culture United States
- Food and drink United States
- Sports activities United States
- Entertainment United States
- Wellness United States