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Apartment vacation rentals in Panama

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Top-rated apartment rentals in Panama

Guests agree: these apartments are highly rated for location, cleanliness, and more.

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Top guest favourite
A comfortable seating area features a wooden couch adorned with light-colored pillows. Large windows provide a view of the lush greenery outside, while a warm light fixture adds a soft glow to the room. The space is complemented by a simple wooden table and concrete flooring.
Apartment in Provincia de Veraguas
4.94 out of 5 average rating, 122 reviews

Casa Melina Torio Cozy upscale 2b jungle apartment

Stylish jungle two bedroom apartment near all major Torio attractions: waterfall, jungle trails, Torio River, Playa Torio & Morrillo Surf break. The apartment is fully equipped with everything you need & want (Hot water, AC, WiFi & TV). Perfect for a couple/family seeking to blend work and play. Casa Melina was designed so our guests can fully experience our Torio culture. Cook with local fresh ingredients, discover Torio on foot & return to rest in the coziest rental you have ever experienced.

Guest favourite
A spacious outdoor area features wooden dining tables surrounded by potted plants. The space includes a plunge pool, comfortable seating, and a hammock for relaxation, with views of the nearby structures and the sky above.
Apartment in Panamá
4.87 out of 5 average rating, 369 reviews

Casco Viejo 360° View Old Tower Penthouse

Located in one of the oldest buildings in Panama and set over 3 stories with unrivaled panoramic views over the historical Casco Viejo, the skyline of Panama City and views of the causeway, our gorgeous penthouse is the ideal space to take in the local sights, sounds, art, culture, socialize with your friends and family, or simply relax in a cozy love nest! Top speed wifi, excellent location, and fully equipped with all the home comforts, the penthouse is the perfect spot to explore Panama.

Top guest favourite
Apartment in Veracruz
5 out of 5 average rating, 8 reviews

On the beach. Entire floor with oceanfront terrace

On the beach with direct access to the sea. Open space studio for 2 people. Living room / kitchen / bedroom 1 (Queen) / sofa / armchair / bathroom with shower, dedicated work space. Large, spectacular terrace on the gulf with bathtub convertible into a sofa. Comfortable, elegant, quiet, and safe. Large and fresh tree-lined garden with tropical fauna and flora. Hummingbirds, iguanas, sometimes monkeys and sloths etc ... Gym equipment, small pool. Perfect for recharging your batteries.

Guest favourite
A serene pool area is set against a clear sky, featuring a spacious swimming pool and lounge chairs arranged around it. Lush green plants add a natural element, enhancing the atmosphere. The backdrop includes a glimpse of the city and distant landscape.
Apartment in Panamá
4.77 out of 5 average rating, 111 reviews

Ocean View private Studio Apartment

The Sands Avenida Balboa, diseñado y pensando en el Viajero activo y aventurero, The Sand Avenida Balboa cuenta con apartamentos tipo estudio amueblado y con acabados, cada apartamento cuenta con una pequeña cocina, baño privado, armario y muebles cómodos; incluyen ventanas de piso a techo. The Sand Avenida Balboa está idealmente ubicado en el corazón de la ciudad de Panamá, Avenida Balboa con fácil acceso al centro, al Casco Antiguo y a menos de 5 minutos de Causeway y el Biomuseo.

Top guest favourite
A communal rooftop space is revealed, showcasing several white-accented chairs and small tables arranged amidst potted plants. The backdrop features a panoramic view of the Panama City skyline against a clear blue sky.
Apartment in Panamá
5 out of 5 average rating, 57 reviews

Tropicool Loft w/rooftop steps from Casco

This historic 1941 loft is located at the entrance of Casco Viejo where you’re steps from the fish market and all the cool cafés, rooftops, and trendy restaurants that make up the neighborhood. Fully equipped kitchen, washer/dryer combo, 1.5 bath, bedroom on 2nd floor, 2 balconies + communal rooftop, projector w/Netflix, fast internet, and great AC. You’re also directly in front of the Cinta Costera park for running, biking, tennis courts. Near local airport for flights to Bocas!

Guest favourite
A hammock sways gently between posts, overlooking calm waters that reflect a clear blue sky. In the distance, a lush island is visible, providing a picturesque backdrop. The green grass leads up to the water's edge, creating a serene outdoor space.
Apartment in Juan Gallego
4.86 out of 5 average rating, 139 reviews

Pebos Reef, apt #2, Amazing views !!

This spectacular beachfront property is ideally situated with an incredible view of neighboring islands, fishing friendly waters, and mesmerizing snorkeling spots for children and adults to enjoy. Monkey greetings from the jungle adjacent, octopus and colorful native fish inhabited waters, and lazy bear sloth sightings are all part of your daily experiences here at Pebos Reef! If you are lucky you will even see dolphins from the terrace ! A terrace on the sea is all you need.

Guest favourite
An open living space features a large gray sectional sofa paired with a round wooden coffee table. A patterned rug lies beneath, complementing the light wooden flooring. The kitchen area is visible in the background, showcasing modern appliances and a breakfast bar with stools.
Apartment in Panamá
4.94 out of 5 average rating, 164 reviews

Cozy 2 Bedroom w/ Splash Pool

Our place is a 3-story apartment located on the quiet side of Casco Viejo. It has a very private feel to it, which allows for an incredible afternoon of sunbathing or bbqing on our private rooftop. The splash pool allows for a refresh and fits 2 people at a time. This place has so much character from with original exposed stone walls, to the sweeping view of the Arto Chato ruins. It also has a great work space, all the necessities to stay in and cook, watch a movie, etc.

Top guest favourite
Apartment in Panamá
4.95 out of 5 average rating, 19 reviews

Gorgeous Flat in the best location in Casco Viejo

This cute and stylish studio is perfectly located in the heart of Casco Viejo, Panama City’s most charming historic district. Recently renovated, it combines modern comfort with classic charm inside a beautiful colonial building—just steps from top restaurants, bars, monuments, and attractions. The space includes a comfortable sofa bed, making it ideal for a couple or a small family looking to enjoy the vibrant atmosphere of Casco right outside their door.

Top guest favourite
Apartment in Panamá
4.98 out of 5 average rating, 163 reviews

The apartment of a legendary Panamanian footballer

Location is everything – just steps away from the city’s best restaurants, bars, stunning churches, and fascinating museums. Explore the historic district on foot while enjoying the comfort of a stylish apartment featuring: • A spectacular balcony with beautiful views • A fully equipped kitchen • 1.5 bathrooms • Cozy beds that make you feel right at home • Surrounded by iconic calicanto stone walls that reflect the charm of Panama’s colonial past.

Top guest favourite
Apartment in Panama City
4.97 out of 5 average rating, 95 reviews

Amazing loft with an iconic view of Casco Viejo

Enjoy a unique experience, in this elegant and centrally-located loft. Fully remodeled 1 bedroom apartment, in a central location in Casco Viejo (the old city). You will be just steps away from many restaurants, cafes, museums, and the existing night life casco has to offer. Located in “Jeronimo,” this restored- colonial building was built in the year 1850, and features unique crafted wall décor, as well as some of the original "calicanto" walls.

Superhost
Apartment in Panamá
5 out of 5 average rating, 5 reviews

Cozy Studio in Cinta Costera with Home Vibes

✨ Live the "Cinta Costera Vibes" experience 🌴 from this modern studio apartment with a panoramic view of the Bay and the vibrant Balboa Avenue. Perfect for travelers looking for comfort, style, and a premium location. Enjoy the pool, restaurant, gym, and rooftop with the best sunset in Panama 🌅. Ideal for short or long stays — your home with home warmth and a 5⭐ touch. Save it as a favorite and live the Host Up experience!

Guest favourite
A spacious studio is bathed in natural light from large windows, offering sweeping views of surrounding mountains and greenery. A comfortable king bed is positioned nearby, while a desk and chair, along with a television, provide a functional work area. A well-equipped kitchen is visible in the foreground.
Apartment in Boquete
4.93 out of 5 average rating, 138 reviews

OMG View from Well Equipped Studio

At CASA EJECUTIVA, this work-ready studio offers comfort and practicality for remote work. Enjoy spectacular views from the king bed, relax, and take in the sights of the town. A comfortable desk, fast internet, solar panels, a battery bank, and backup water ensure you stay connected and powered during outages. The fully equipped kitchen completes the space, providing everything needed for both work and leisure.

Popular amenities for Panama apartment rentals

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