
Boutique hotel vacation rentals in Panama City
Find and book unique boutique hotels on Airbnb
Top-rated boutique hotels in Panama City
Guests agree: these boutique hotel rentals are highly rated for location, cleanliness, and more.
Vacation rentals for every style
Get the amount of space that is right for you.
Popular amenities for Panama City boutique hotels
Family-friendly boutique hotels

Charming Hotel in Casco Viejo Santa Ana Deluxe

Private rooms Sofia's B&B Hostal Boutique

Suite Room in the ORHO Hotel

Beautiful loft #5 - kingsize bed

Blue Room in the ORHO Hotel

Eshel Panama Suites, Atlantic suite 04

Pool side, Family suite, two bedroom one bath.

Entire place Sofia's B&B Hostal Boutique
Boutique hotels with a patio

Eshel Panama Suites, Crown suite 07

Shangai Room in the ORHO Hotel

Eshel suites Panama , Suite Kingston 02

Taboga Palace Hotel. Beach front English Bouquet

Sky Room in the ORHO Hotel
Other boutique hotel vacation rentals

Charming Hotel in Casco Viejo Santa Ana Deluxe

Private rooms Sofia's B&B Hostal Boutique

Suite Room in the ORHO Hotel

Beautiful loft #5 - kingsize bed

The Corner Suite #110 | La Résidence Panamá

Eshel Panama Suites, Atlantic suite 04

Pool side, Family suite, two bedroom one bath.

Entire place Sofia's B&B Hostal Boutique
Quick stats about boutique hotel rentals in Panama City
Total rentals
20 properties
Nightly prices starting at
$42 CAD before taxes and fees
Total number of reviews
280 reviews
Rentals with dedicated workspaces
10 properties have a dedicated workspace
Wifi availability
20 properties include access to wifi
Popular amenities
Kitchen, Wifi, and Pool
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- Things to do Panama City
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- Things to do Panama
- Sports activities Panama
- Food and drink Panama
- Nature and outdoors Panama
- Entertainment Panama
- Sightseeing Panama
- Tours Panama
- Art and culture Panama