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Boutique hotel vacation rentals in Panama

Find and book unique boutique hotels on Airbnb

Top-rated boutique hotels in Panama

Guests agree: these boutique hotel rentals are highly rated for location, cleanliness, and more.

Superhost
Boutique hotel in Bajo Boquete
Villa Alejandro - Tastefully Furnished Room
Just 5 minutes walk to centre, calmly situated and close to town located in an extraordinary mansion. Lovely furnished bedroom (King-Size/Orthopedic mattress) with private bathroom and walk-in closet . Affectionately decorated living room with spectacular view to the Boquete valley by large windows and large, full equipped kitchen can be shared with other guests. Lot of space for dining/reading in the living room. Lovely garden and terrace can be used. Gated carport. Fast WiFi, CableTV, Netflix
Jun. 20 – 27
$126 CAD per night
4.91 out of 5 average rating, 105 reviews
Superhost
Boutique hotel in PA
Rancho Cabaña- Private Porch, Loft, 1 min to beach
No detail left unnoticed…our boutique cabañas are nestled in jungle gardens with private porches overlooking the Pacific, hammocks for lounging, indoor/outdoor concept bathrooms, stunning hardwood floors, and custom-made furniture. Each of our three cabañas has its own unique charm where comfort meets luxury. We are steps from the beach and minutes from consistent surf breaks and community yoga classes. A shared kitchen is on site, with individual cooking utensils provided for each room.
Jul. 12 – 19
$115 CAD per night
4.84 out of 5 average rating, 43 reviews
Superhost
Boutique hotel in PA
Villa Coco King Room
Villa Coco is a beautiful boutique hotel in Santa Catalina, only footsteps away of the world known surf break “La Punta” and Unesco world heritage Coiba island. The carefully designed cabañas, provide a space of tranquility and a sense of timelessness. Unwind in the hammocks and canvas chairs on your private terrace, dwell on reading your favorite book or sip on a cool drink from the bar. Our Restaurant “Ai Mamita” offers different kinds of meat, fresh seafood and other tasty delights.
Jul. 10 – 17
$234 CAD per night
4.89 out of 5 average rating, 28 reviews

Popular amenities for Panama boutique hotels

Family-friendly boutique hotels

Boutique hotel in San Carlos
B) Beach, surf and Relax with King size bed
Jun. 5 – 12
$94 CAD per night
4.83 out of 5 average rating, 84 reviews
Guest favourite
Boutique hotel in Copecito
B&B Cabanas los hummingbirds
Jan. 27 – Feb. 3
$132 CAD per night
4.79 out of 5 average rating, 29 reviews
Boutique hotel in Playa Morillo, Mariato
Double room IXORA with partial ocean view balcony
Oct. 27 – Nov. 3
$157 CAD per night
4.97 out of 5 average rating, 33 reviews
Guest favourite
Boutique hotel in Punta Chame
Pink Palace Panama
Aug. 2 – 9
$144 CAD per night
5.0 out of 5 average rating, 7 reviews
Boutique hotel in Playa Venao
Marea - Ocean View Room with King Sized Bed
Mar. 3 – 10
$236 CAD per night
4.86 out of 5 average rating, 7 reviews
Boutique hotel in Boquete
Cabañas Villa San Miguel #5 / Boquete.
Dec. 21 – 28
$107 CAD per night
4.76 out of 5 average rating, 58 reviews
Hotel room in Puerto Armuelles
Beachfront Ocean Suite with Swiming Pool
Mar. 5 – 12
$142 CAD per night
4.53 out of 5 average rating, 19 reviews
Boutique hotel in isla contadora.
Beautiful B&B with unbeatable customer care!!!
Sep. 6 – 13
$247 CAD per night
4.75 out of 5 average rating, 8 reviews
Boutique hotel in Portobelo
Beachfront Boutique Hotel and Restaurant Portobelo
Jul. 28 – Aug. 4
$154 CAD per night
New place to stay
Superhost
Boutique hotel in Soná
Villa Coco Twin Room
May 10 – 17
$202 CAD per night
5.0 out of 5 average rating, 4 reviews
Superhost
Boutique hotel in Soná
Villa Coco Jungle Villa
Dec. 2 – 9
$410 CAD per night
New place to stay
Boutique hotel in San Carlos
D) just a walk to the beach (Manglar Lodge)
Jun. 18 – 25
$97 CAD per night
4.8 out of 5 average rating, 56 reviews

Boutique hotels with a patio

Guest favourite
Boutique hotel in El Valle de Antón
Suite medievale natura & arte
Mar. 6 – 13
$133 CAD per night
4.38 out of 5 average rating, 8 reviews
Boutique hotel in Pedasi
Room in Boutique Hostel; Private Bathroom
Mar. 11 – 18
$75 CAD per night
4.83 out of 5 average rating, 12 reviews
Boutique hotel in Boca Chica
Tranquil Ocean View Cottage At Seagull Cove Resort
Sep. 8 – 15
$235 CAD per night
4.75 out of 5 average rating, 4 reviews
Boutique hotel in Bocas del Toro
Over the Sea Turtle Mini Cabin with Veranda
Apr. 8 – 15
$147 CAD per night
4.71 out of 5 average rating, 14 reviews
Boutique hotel in Soná District
Garden View Double Bedroom at Nativo
Jul. 5 – 12
$122 CAD per night
4.5 out of 5 average rating, 6 reviews
Boutique hotel in San Carlos
La Maracuyá Panama_ splendid large Room in Nature
Jun. 17 – 24
$136 CAD per night
5.0 out of 5 average rating, 3 reviews
Boutique hotel in Cambutal
Oceanfront Healing Sanctuary & Spa sunset
Mar. 20 – 27
$221 CAD per night
New place to stay
Boutique hotel in Panamá
Eshel suites Panama , Suite Kingston 02
Jul. 30 – Aug. 6
$183 CAD per night
New place to stay
Boutique hotel in PA
Vida Lotus King Room with Hot Tub, Desk, and TV
Aug. 28 – Sep. 4
$185 CAD per night
New place to stay
Boutique hotel in Panamá
Charming Hotel in Casco Viejo Santa Ana Deluxe
Jan. 3 – 10
$380 CAD per night
New place to stay
Boutique hotel in Panamá
Beautiful Private Apartment in Old Town
Apr. 9 – 16
$228 CAD per night
New place to stay
Guest favourite
Boutique hotel in Bajo Boquete
The Residence - Colibri Room
Aug. 26 – Sep. 2
$94 CAD per night
5.0 out of 5 average rating, 16 reviews

Monthly boutique hotel rentals

Hotel room in Bajo Boquete
Buena Vista Boquete Quadruple Room
Apr. 25 – May 23
$1,302 CAD per month
4.77 out of 5 average rating, 62 reviews
Boutique hotel in El Valle de Antón
HOSTAL EL MAJO DEL VALLE II
May 7 – Jun. 4
$1,196 CAD per month
4.56 out of 5 average rating, 93 reviews
Boutique hotel in Bocas del Toro
Private Double Room With Private Bathroom A/C WiFi
Nov. 25 – Dec. 23
$908 CAD per month
4.19 out of 5 average rating, 16 reviews
Shared hotel room in Las Escobas del Venado
Selina Playa Venao - Bed in Dorm
Jul. 2 – 30
$1,211 CAD per month
New place to stay
Shared hotel room in Bocas del Toro
Selina Bocas del Toro - Bed in Small Dorm
Jul. 28 – Aug. 25
$1,157 CAD per month
New place to stay
Shared hotel room in Bastimentos Island
Selina Bocas del Toro Red Frog - Bed in Small Dorm
Jun. 30 – Jul. 28
$1,128 CAD per month
New place to stay
Boutique hotel in Panamá
Hotel san Roque
Mar. 4 – Apr. 1
$1,272 CAD per month
New place to stay
Boutique hotel in David
Near bus station and downtown in David, Chiriqui
Feb. 15 – Mar. 15
$1,168 CAD per month
New place to stay
Shared hotel room in Bocas del Toro
Selina Bocas del Toro - Bed in Large Dorm
Oct. 24 – Nov. 21
$1,108 CAD per month
4.23 out of 5 average rating, 13 reviews

Destinations to explore