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Boutique hotel vacation rentals in Panama

Find and book unique boutique hotels on Airbnb

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Popular amenities for Panama boutique hotels

Family-friendly boutique hotels

Guest favourite
Hotel room in Playa Venao
5 out of 5 average rating, 12 reviews

Brisa - Ocean Views, Calm Vibes, King/Twin beds

KristinaRating, 5 stars1 month ago
El Sitio exceeded our expectations. The staff are warm, helpful, and professional. We arrived late and the staff were wonderful at checking us in and getting us settled. The suite was beyond the pictures. The hotel is right on the beach, perfect for us as we were surfing. The restaurant on site was equally amazing, exceeded expectations, and reasonably priced. The bar and restaurant staff were fantastic. In the late afternoon each day a dj would spin until after sunset. The only thing we wished was that we could have stayed longer. Whether for a relaxing trip, surf and sun, family, romance or a friends trip, we highly recommend visiting Playa Venao and staying with the folks at El Sitio. It is truly a magical place!
Hotel room in isla contadora.
4.75 out of 5 average rating, 8 reviews

Beautiful B&B with unbeatable customer care!!!

Alma RosaRating, 5 stars36 months ago
The beach is very close by walking, but in the heat it is difficult to walk long distances. It is considerable to rent a cart early to ensure availability
Guest favourite
Hotel room in PA
4.91 out of 5 average rating, 34 reviews

Villa Coco King Room

JuliRating, 5 stars2 months ago
We thoroughly enjoyed our stay. There is nothing that could have been better. A beautiful place that we would book again at any time. Highly recommend!
Hotel room in San Carlos
4.75 out of 5 average rating, 32 reviews

B&B Cabanas los hummingbirds

ShelleyRating, 5 stars15 months ago
Magali was a gracious host who cares for both the accommodations and her guests. The cabana is peaceful and well equipped. I will return on my next trip to Panama. The breakfast is delicious. Warmly, Shelley
Hotel room in Punta Chame
5 out of 5 average rating, 9 reviews

Pink Palace Panama

AlejandroRating, 5 stars10 months ago
Great experience at Peggy's place, a top-notch hostess! Sweet, attentive and very helpful. Important that they know that they have 3 dogs, they are very friendly. The house is facing the sea, just steps walking to the shore.
Hotel room in Playa Morillo, Mariato
4.94 out of 5 average rating, 36 reviews

Double room IXORA with partial ocean view balcony

NathanRating, 5 stars3 months ago
Gabriele’s place is a true hidden gem! The views are incredible (even though it was cloudy the entire time we were there, they were still stunning - I am sure on a clearer afternoon the sunset is spectacular), the accommodations are clean, comfortable and spacious, and the food offered (breakfast, lunch and dinner can be ordered onsite - menu changes daily) was really, really delicious - she even has a very nice wine list as well! The main road off the interamericana is in beautiful shape - the 6km road/driveway to get to the property is dirt but is passable with a normal car as long as you take it slow. Gabriele was a great host - accommodating, responsive, and caring. If you are looking for a peaceful and relaxing retreat, give her place a try!!
Hotel room in Boquete
4.73 out of 5 average rating, 62 reviews

Villa San Miguel | Cabin #5 | Boquete

IstvánRating, 5 stars3 months ago
We had a wonderful stay there! The garden is just amazing!

Boutique hotels with a patio

Guest favourite
Hotel room in Boquete
4.88 out of 5 average rating, 26 reviews

La Residencia - Colibri Room

SamanthaRating, 5 stars4 months ago
Perfect location for leisurely walk to downtown Boquete, which is in easy reach: enjoy its hustle & bustle, then return to peace & tranquility at the Residence, which is surrounded by pure raw nature. The garden lends itself to tropical trees & plants & receives frequent visits from an assortment of birds and butterflies. The topography landscape view in, around & from the Property is spectacular. The surrounding mountains with their tops partially hidden behind steams of mists & clouds is mesmerising: picture perfect! The Property was always clean & tidy. The communal seating is spacious: the kitchen fully functional & fitting with high quality electrical appliances & an assortment of cooking implements. The staff were professional, friendly & always greeted with a warm smile: someone was always on hand to assist with my queries. I thank all the staff whom I had encountered, for their kindness, assistance & for making me feel at home & yes, I will surely visit again.
Hotel room in Lagartero
4.73 out of 5 average rating, 15 reviews

Charming 1-Bedroom Beachfront Hotel With Pool

AlexanderRating, 5 stars1 month ago
The hotel, with its various houses, is a true paradise! We received a warm welcome and a guided tour of the beautiful property. The beachfront house is definitely a highlight – modernly equipped and offering breathtaking views. Falling asleep to the sound of the ocean at night was simply magical. Mike was always friendly and helpful. An unforgettable stay – highly recommended!
Hotel room in Soná District
4.5 out of 5 average rating, 6 reviews

Garden View Double Bedroom at Nativo

AlanRating, 5 stars26 months ago
Peaceful stay. We were able to enjoy the wonderful view and cocktails offered by the hotel. We will not excite advising this location for our friends if they owe in Santa Catalina.
Guest favourite
Hotel room in Boca Chica
4.89 out of 5 average rating, 9 reviews

Tranquil Ocean View Cottage At Seagull Cove Resort

HannahRating, 5 stars12 months ago
Great place to stay! The views from our room and restaurant were amazing, our room was comfortable and clean. The restaurant was really good, the breakfast selection is fresh with a different fresh juice of the day, for lunch or dinner I definitely recommend the bruschetta starter and either of the tacos. So with great location, tasty food, comfortable room my favourite part was actually the staff as they were so friendly and helpful, from the front of house to the gardener and housekeeper, they are a great team and made our stay extra special.
Hotel room in Panamá
5 out of 5 average rating, 3 reviews

Eshel Panama Suites, Atlantic suite 04

ChanochRating, 5 stars10 months ago
Great host, beautiful place, great location! Enjoyed the stay!
Hotel room in Bocas del Toro
4.65 out of 5 average rating, 20 reviews

Over the Sea Turtle Mini Cabin with Veranda

SandyRating, 5 stars2 months ago
Cute place. Liked the over-the-water bungalows.
Superhost
Hotel room in Cambutal
4.91 out of 5 average rating, 11 reviews

Boutique Inn_The Hill 3_Private Entry_Sea View_16+

FernandoRating, 5 stars8 months ago
My room was decorated with excellent taste (the photos are accurate), very confortable and the bed, huge and relaxingly firm. The view over the garden and the sea from inside as well as from its private terrace are one of its best features. The internet connection is fast, which allowed me to work from there and have conf calls without any problem. The kitchen, gravity center of the Hill, is beautiful and perfectly equipped. The common areas are very well designed - as befits the house - and actually make you want to stay there all day. But there's so much to do in Cambutal. On top of hanging out on its black sand beach set against the tropical greenery, there's good surfing spots, hikes in the jungle, swimming in cascade pools...Stephan had very good advice and helped me organize all these activities. I had such a great time there that I extended my stay and would have stayed more if I could.
Top guest favourite
Hotel room in Cambutal
5 out of 5 average rating, 10 reviews

Boutique Inn_The Hill 4_Private Entry_16+

MajaRating, 5 stars4 months ago
I can wholeheartedly recommend Stephan and Duy’s place. The house and surroundings are stunning, and the hosts are warm, friendly and helpful. The only backside of our stay was that we needed to work (which is totally feasible thanks to good WiFi, desk etc). We hope to return soon. Thanks again Stephan and Duy 😊

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